{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T17:42:47Z","timestamp":1777398167527,"version":"3.51.4"},"publisher-location":"Boston, MA","reference-count":115,"publisher":"Springer US","isbn-type":[{"value":"9780387771021","type":"print"},{"value":"9780387771038","type":"electronic"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2009]]},"DOI":"10.1007\/b109924_13","type":"book-chapter","created":{"date-parts":[[2009,10,15]],"date-time":"2009-10-15T14:02:01Z","timestamp":1255615321000},"page":"195-213","source":"Crossref","is-referenced-by-count":12,"title":["Auditory Late Effects of Chemotherapy"],"prefix":"10.1007","author":[{"given":"Anna K.","family":"Meyer","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nancy M.","family":"Young","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2009,6,29]]},"reference":[{"key":"13_CR1","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1002\/1097-0142(19840115)53:2<224::AID-CNCR2820530207>3.0.CO;2-D","volume":"53","author":"SA Fausti","year":"1984","unstructured":"Fausti SA, Schechter MA, Rappaport BZ, et al. Early detection of cisplatin ototoxicity. Selected case reports. Cancer. 1984;53:224 231.","journal-title":"Cancer"},{"key":"13_CR2","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1097\/01.mph.0000141348.62532.73","volume":"26","author":"P Bertolini","year":"2004","unstructured":"Bertolini P, Lassalle M, Mercier G, et al. Platinum compound-related ototoxicity in children: long-term follow-up reveals continuous worsening of hearing loss. J Pediatr Hematol Oncol. 2004;26:649 655.","journal-title":"J Pediatr Hematol Oncol"},{"key":"13_CR3","doi-asserted-by":"crossref","first-page":"1191","DOI":"10.1200\/JCO.1990.8.7.1191","volume":"8","author":"CS Kretschmar","year":"1990","unstructured":"Kretschmar CS, Warren MP, Lavally BL, et al. Ototoxicity of preradiation cisplatin for children with central nervous system tumors. J Clin Oncol. 1990;8:1191 1198.","journal-title":"J Clin Oncol"},{"key":"13_CR4","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1002\/cncr.22004","volume":"107","author":"BH Kushner","year":"2006","unstructured":"Kushner BH, Budnick A, Kramer K, et al. Ototoxicity from high-dose use of platinum compounds in patients with neuroblastoma. Cancer. 2006;107:417 422.","journal-title":"Cancer"},{"key":"13_CR5","doi-asserted-by":"crossref","first-page":"2445","DOI":"10.1016\/j.ejca.2003.08.009","volume":"40","author":"Y Li","year":"2004","unstructured":"Li Y, Womer RB, Silber JH. Predicting cisplatin ototoxicity in children: the influence of age and the cumulative dose. Eur J Cancer. 2004;40:2445 2451.","journal-title":"Eur J Cancer"},{"key":"13_CR6","doi-asserted-by":"crossref","first-page":"927","DOI":"10.1038\/bjc.1990.208","volume":"61","author":"R Skinner","year":"1990","unstructured":"Skinner R, Pearson AD, Amineddine HA, et al. Ototoxicity of cisplatinum in children and adolescents. Br J Cancer. 1990;61:927 931.","journal-title":"Br J Cancer"},{"key":"13_CR7","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1177\/019459989310900302","volume":"109","author":"BW Blakley","year":"1993","unstructured":"Blakley BW, Myers SF. Patterns of hearing loss resulting from cis-platinum therapy. Otolaryngol Head Neck Surg. 1993;109:385 391.","journal-title":"Otolaryngol Head Neck Surg."},{"key":"13_CR8","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1002\/mpo.2950190415","volume":"19","author":"PR Brock","year":"1991","unstructured":"Brock PR, Bellman SC, Yeomans EC, et al. Cisplatin ototoxicity in children: a practical grading system. Med Pediatr Oncol. 1991;19:295 300.","journal-title":"Med Pediatr Oncol."},{"key":"13_CR9","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1002\/(SICI)1096-911X(199607)27:1<26::AID-MPO6>3.0.CO;2-W","volume":"27","author":"I Ilveskoski","year":"1996","unstructured":"Ilveskoski I, Saarinen UM, Wiklund T, et al. Ototoxicity in children with malignant brain tumors treated with the \u201c8 in 1\u201d chemotherapy protocol. Med Pediatr Oncol. 1996;27:26 31.","journal-title":"Med Pediatr Oncol."},{"key":"13_CR10","first-page":"14","volume":"22","author":"M Montaguti","year":"2002","unstructured":"Montaguti M, Brandolini C, Ferri GG, et al.[Cisplatin and carboplatin-induced ototoxicity in children: clinical aspects and perspectives for prevention]. Acta Otorhinolaryngol Ital. 2002;22:14 18.","journal-title":"Acta Otorhinolaryngol Ital."},{"key":"13_CR11","doi-asserted-by":"crossref","first-page":"1355","DOI":"10.1038\/bjc.1998.226","volume":"77","author":"C Bokemeyer","year":"1998","unstructured":"Bokemeyer C, Berger CC, Hartmann JT, et al. Analysis of risk factors for cisplatin-induced ototoxicity in patients with testicular cancer. Br J Cancer. 1998;77:1355 1362.","journal-title":"Br J Cancer"},{"key":"13_CR12","doi-asserted-by":"crossref","first-page":"669","DOI":"10.1038\/sj.bmt.1701391","volume":"22","author":"SK Parsons","year":"1998","unstructured":"Parsons SK, Neault MW, Lehmann LE, et al. Severe ototoxicity following carboplatin-containing conditioning regimen for autologous marrow transplantation for neuroblastoma. Bone Marrow Transplant. 1998;22:669 674.","journal-title":"Bone Marrow Transplant."},{"key":"13_CR13","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1016\/0090-8258(83)90100-2","volume":"16","author":"RL Brown","year":"1983","unstructured":"Brown RL, Nuss RC, Patterson R, et al. Audiometric monitoring of cis-platinum ototoxicity. Gynecol Oncol. 1983;16:254 262.","journal-title":"Gynecol Oncol."},{"key":"13_CR14","doi-asserted-by":"crossref","first-page":"1934","DOI":"10.1002\/1097-0142(19851015)56:8<1934::AID-CNCR2820560807>3.0.CO;2-F","volume":"56","author":"SD Schaefer","year":"1985","unstructured":"Schaefer SD, Post JD, Close LG, et al. Ototoxicity of low- and moderate-dose cisplatin. Cancer. 1985;56:1934 1939.","journal-title":"Cancer"},{"key":"13_CR15","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1002\/jso.2930160203","volume":"16","author":"NV Aguilar-Markulis","year":"1981","unstructured":"Aguilar-Markulis NV, Beckley S, Priore R, et al. Auditory toxicity effects of long-term cis-dichlorodiammineplatinum II therapy in genitourinary cancer patients. J Surg Oncol. 1981;16:111 123.","journal-title":"J Surg Oncol."},{"key":"13_CR16","doi-asserted-by":"crossref","first-page":"1631","DOI":"10.1016\/j.ijporl.2007.06.021","volume":"71","author":"MT Truong","year":"2007","unstructured":"Truong MT, Winzelberg J, Chang KW. Recovery from cisplatin-induced ototoxicity: a case report and review. Int J Pediatr Otorhinolaryngol. 2007;71:1631 1638.","journal-title":"Int J Pediatr Otorhinolaryngol."},{"key":"13_CR17","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1159\/000120545","volume":"16","author":"BH Cohen","year":"1990","unstructured":"Cohen BH, Zweidler P, Goldwein JW, et al. Ototoxic effect of cisplatin in children with brain tumors. Pediatr Neurosurg. 1990;16:292 296.","journal-title":"Pediatr Neurosurg."},{"key":"13_CR18","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1002\/(SICI)1096-911X(199602)26:2<95::AID-MPO5>3.0.CO;2-P","volume":"26","author":"RJ Freilich","year":"1996","unstructured":"Freilich RJ, Kraus DH, Budnick AS, et al. Hearing loss in children with brain tumors treated with cisplatin and carboplatin-based high-dose chemotherapy with autologous bone marrow rescue. Med Pediatr Oncol. 1996;26:95 100.","journal-title":"Med Pediatr Oncol."},{"key":"13_CR19","doi-asserted-by":"crossref","first-page":"90","DOI":"10.3109\/00016489709124092","volume":"529","author":"S Miettinen","year":"1997","unstructured":"Miettinen S, Laurikainen E, Johansson R, et al. Radiotherapy enhanced ototoxicity of cisplatin in children. Acta Otolaryngol Suppl. 1997;529:90 94.","journal-title":"Acta Otolaryngol Suppl."},{"key":"13_CR20","doi-asserted-by":"crossref","first-page":"754","DOI":"10.1200\/JCO.1989.7.6.754","volume":"7","author":"MJ Schell","year":"1989","unstructured":"Schell MJ, McHaney VA, Green AA, et al. Hearing loss in children and young adults receiving cisplatin with or without prior cranial irradiation. J Clin Oncol. 1989;7:754 760.","journal-title":"J Clin Oncol."},{"key":"13_CR21","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1055\/s-2002-33179","volume":"214","author":"T Simon","year":"2002","unstructured":"Simon T, Hero B, Dupuis W, et al. The incidence of hearing impairment after successful treatment of neuroblastoma. Klin Padiatr. 2002;214:149 152.","journal-title":"Klin Padiatr."},{"key":"13_CR22","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/0305-7372(85)90027-1","volume":"12 Suppl A","author":"R Canetta","year":"1985","unstructured":"Canetta R, Rozencweig M, Carter SK. Carboplatin: the clinical spectrum to date. Cancer Treat Rev. 1985;12 Suppl A:125 136.","journal-title":"Cancer Treat Rev."},{"key":"13_CR23","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1200\/JCO.1989.7.2.173","volume":"7","author":"FJ Meyers","year":"1989","unstructured":"Meyers FJ, Welborn J, Lewis JP, et al. Infusion carboplatin treatment of relapsed and refractory acute leukemia: evidence of efficacy with minimal extramedullary toxicity at intermediate doses. J Clin Oncol. 1989;7:173 178.","journal-title":"J Clin Oncol."},{"key":"13_CR24","doi-asserted-by":"crossref","first-page":"1297","DOI":"10.1002\/1097-0142(19940215)73:4<1297::AID-CNCR2820730427>3.0.CO;2-#","volume":"73","author":"LJ Ettinger","year":"1994","unstructured":"Ettinger LJ, Gaynon PS, Krailo MD, et al. A phase II study of carboplatin in children with recurrent or progressive solid tumors. A report from the Children\u2019s Cancer Group. Cancer. 1994;73:1297 1301.","journal-title":"Cancer."},{"key":"13_CR25","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1002\/pbc.21155","volume":"50","author":"MP Lambert","year":"2008","unstructured":"Lambert MP, Shields C, Meadows AT. A retrospective review of hearing in children with retinoblastoma treated with carboplatin-based chemotherapy. Pediatr Blood Cancer. 2008;50:223 226.","journal-title":"Pediatr Blood Cancer"},{"key":"13_CR26","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1002\/mpo.10134","volume":"39","author":"JW Stern","year":"2002","unstructured":"Stern JW, Bunin N. Prospective study of carboplatin-based chemotherapy for pediatric germ cell tumors. Med Pediatr Oncol. 2002;39:163 167.","journal-title":"Med Pediatr Oncol."},{"key":"13_CR27","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1007\/BF02897206","volume":"26","author":"IC Kennedy","year":"1990","unstructured":"Kennedy IC, Fitzharris BM, Colls BM, et al. Carboplatin is ototoxic. Cancer Chemother Pharmacol. 1990;26:232 234.","journal-title":"Cancer Chemother Pharmacol"},{"key":"13_CR28","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/0037-0738(88)90002-4","volume":"58","author":"JRL. Allen","year":"1988","unstructured":"Allen JRL. Modern-period muddy sediments in the severn estuary (Southwestern UK) A pollutant-based model for dating and correlation. Sedimentary Geol. 1988;58:1.","journal-title":"Sedimentary Geol"},{"key":"13_CR29","first-page":"151","volume":"23","author":"MR Macdonald","year":"1994","unstructured":"Macdonald MR, Harrison RV, Wake M, et al. Ototoxicity of carboplatin: comparing animal and clinical models at the Hospital for Sick Children. J Otolaryngol. 1994;23:151 159.","journal-title":"J Otolaryngol"},{"key":"13_CR30","first-page":"493","volume":"7","author":"ND Doolittle","year":"2001","unstructured":"Doolittle ND, Muldoon LL, Brummett RE, et al. Delayed sodium thiosulfate as an otoprotectant against carboplatin-induced hearing loss in patients with malignant brain tumors. Clin Cancer Res. 2001;7:493 500.","journal-title":"Clin Cancer Res"},{"key":"13_CR31","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1227\/00006123-199507000-00003","volume":"37","author":"PC Williams","year":"1995","unstructured":"Williams PC, Henner WD, Roman-Goldstein S, et al. Toxicity and efficacy of carboplatin and etoposide in conjunction with disruption of the blood-brain tumor barrier in the treatment of intracranial neoplasms. Neurosurgery. 1995;37:17 27; discussion -8.","journal-title":"Neurosurgery"},{"key":"13_CR32","doi-asserted-by":"crossref","first-page":"320","DOI":"10.1007\/BF01732887","volume":"61","author":"G Lugassy","year":"1990","unstructured":"Lugassy G, Shapira A. Sensorineural hearing loss associated with vincristine treatment. Blut. 1990;61:320 321.","journal-title":"Blut"},{"key":"13_CR33","doi-asserted-by":"crossref","first-page":"530","DOI":"10.1179\/joc.2000.12.6.530","volume":"12","author":"I Aydogdu","year":"2000","unstructured":"Aydogdu I, Ozturan O, Kuku I, et al. Bilateral transient hearing loss associated with vincristine therapy: case report. J Chemother. 2000;12:530 532.","journal-title":"J Chemother."},{"key":"13_CR34","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/j.ijporl.2006.09.001","volume":"71","author":"M Riga","year":"2007","unstructured":"Riga M, Psarommatis I, Korres S, et al. Neurotoxicity of vincristine on the medial olivocochlear bundle. Int J Pediatr Otorhinolaryngol. 2007;71:63 69.","journal-title":"Int J Pediatr Otorhinolaryngol"},{"key":"13_CR35","first-page":"365","volume":"12","author":"MJ Moroso","year":"1983","unstructured":"Moroso MJ, Blair RL. A review of cis-platinum ototoxicity. J Otolaryngol. 1983;12:365 369.","journal-title":"J Otolaryngol"},{"key":"13_CR36","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/BF00464398","volume":"242","author":"K Boheim","year":"1985","unstructured":"Boheim K, Bichler E. Cisplatin-induced ototoxicity: audiometric findings and experimental cochlear pathology. Arch Otorhinolaryngol. 1985;242:1 6.","journal-title":"Arch Otorhinolaryngol"},{"key":"13_CR37","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1177\/019459988108900226","volume":"89","author":"S Komune","year":"1981","unstructured":"Komune S, Asakuma S, Snow JB, Jr. Pathophysiology of the ototoxicity of cis-diamminedichloroplatinum. Otolaryngol Head Neck Surg. 1981;89:275 282.","journal-title":"Otolaryngol Head Neck Surg"},{"key":"13_CR38","doi-asserted-by":"crossref","first-page":"825","DOI":"10.1016\/S0194-5998(98)70276-1","volume":"118","author":"DL Hoistad","year":"1998","unstructured":"Hoistad DL, Ondrey FG, Mutlu C, et al. Histopathology of human temporal bone after cis-platinum, radiation, or both. Otolaryngol Head Neck Surg. 1998;118:825 832.","journal-title":"Otolaryngol Head Neck Surg"},{"key":"13_CR39","first-page":"731","volume":"16","author":"R Hinojosa","year":"1995","unstructured":"Hinojosa R, Riggs LC, Strauss M, et al. Temporal bone histopathology of cisplatin ototoxicity. Am J Otol. 1995;16:731 740.","journal-title":"Am J Otol"},{"key":"13_CR40","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1006\/taap.2001.9171","volume":"174","author":"N Dehne","year":"2001","unstructured":"Dehne N, Lautermann J, Petrat F, et al. Cisplatin ototoxicity: involvement of iron and enhanced formation of superoxide anion radicals. Toxicol Appl Pharmacol. 2001;174:27 34.","journal-title":"Toxicol Appl Pharmacol"},{"key":"13_CR41","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/0378-5955(94)90060-4","volume":"75","author":"S Takeno","year":"1994","unstructured":"Takeno S, Harrison RV, Ibrahim D, et al. Cochlear function after selective inner hair cell degeneration induced by carboplatin. Hear Res. 1994;75:93 102.","journal-title":"Hear Res"},{"key":"13_CR42","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1016\/S0360-3016(96)00302-1","volume":"36","author":"DL Kwong","year":"1996","unstructured":"Kwong DL, Wei WI, Sham JS, et al. Sensorineural hearing loss in patients treated for nasopharyngeal carcinoma: a prospective study of the effect of radiation and cisplatin treatment. Int J Radiat Oncol Biol Phys.1996;36:281 289.","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"13_CR43","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1002\/mpo.2950170110","volume":"17","author":"DA Walker","year":"1989","unstructured":"Walker DA, Pillow J, Waters KD, et al. Enhanced cis-platinum ototoxicity in children with brain tumours who have received simultaneous or prior cranial irradiation. Med Pediatr Oncol. 1989;17:48 52.","journal-title":"Med Pediatr Oncol"},{"key":"13_CR44","doi-asserted-by":"crossref","first-page":"8588","DOI":"10.1200\/JCO.2004.00.5355","volume":"23","author":"KR Knight","year":"2005","unstructured":"Knight KR, Kraemer DF, Neuwelt EA. Ototoxicity in children receiving platinum chemotherapy: underestimating a commonly occurring toxicity that may influence academic and social development. J Clin Oncol. 2005;23:8588 8596.","journal-title":"J Clin Oncol"},{"key":"13_CR45","doi-asserted-by":"crossref","first-page":"599","DOI":"10.1016\/S0360-3016(01)02641-4","volume":"52","author":"E Huang","year":"2002","unstructured":"Huang E, Teh BS, Strother DR, et al. Intensity-modulated radiation therapy for pediatric medulloblastoma: early report on the reduction of ototoxicity. Int J Radiat Oncol Biol Phys. 2002;52:599 605.","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"13_CR46","doi-asserted-by":"crossref","first-page":"917","DOI":"10.1288\/00005537-199109000-00001","volume":"101","author":"RA Weatherly","year":"1991","unstructured":"Weatherly RA, Owens JJ, Catlin FI, et al. Cis-platinum ototoxicity in children. Laryngoscope. 1991;101:917 924.","journal-title":"Laryngoscope"},{"key":"13_CR47","first-page":"314","volume":"83","author":"TG McHaney VA","year":"1983","unstructured":"McHaney VA TG, Hayes FA. Hearing loss in children receiving cisplatin chemotherapy. K Pediatr. 1983;83:314 317.","journal-title":"K Pediatr"},{"key":"13_CR48","doi-asserted-by":"crossref","first-page":"985","DOI":"10.1288\/00005537-199109000-00010","volume":"101","author":"TR Pasic","year":"1991","unstructured":"Pasic TR, Dobie RA. Cis-platinum ototoxicity in children. Laryngoscope. 1991;101:985 991.","journal-title":"Laryngoscope"},{"key":"13_CR49","doi-asserted-by":"crossref","first-page":"918","DOI":"10.1200\/JCO.2006.10.077","volume":"24","author":"JM Rademaker-Lakhai","year":"2006","unstructured":"Rademaker-Lakhai JM, Crul M, Zuur L, et al. Relationship between cisplatin administration and the development of ototoxicity. J Clin Oncol. 2006;24:918 924.","journal-title":"J Clin Oncol"},{"key":"13_CR50","doi-asserted-by":"crossref","first-page":"1748","DOI":"10.1200\/JCO.1989.7.11.1748","volume":"7","author":"AH Calvert","year":"1989","unstructured":"Calvert AH, Newell DR, Gumbrell LA, et al. Carboplatin dosage: prospective evaluation of a simple formula based on renal function. J Clin Oncol. 1989;7:1748 1756.","journal-title":"J Clin Oncol"},{"key":"13_CR51","doi-asserted-by":"crossref","first-page":"1823","DOI":"10.1016\/S0959-8049(97)00341-9","volume":"33","author":"B Peng","year":"1997","unstructured":"Peng B, English MW, Boddy AV, et al. Cisplatin pharmacokinetics in children with cancer. Eur J Cancer. 1997;33:1823 1828.","journal-title":"Eur J Cancer"},{"key":"13_CR52","first-page":"2279","volume":"14","author":"B BA Peng","year":"1994","unstructured":"Peng B BA, English MW, et al. The comparative pharmacokinetics and pharmacodynamics of cisplatin and carboplatin in paediatric patients: a review. Anticancer Res. 1994;14:2279 2283.","journal-title":"Anticancer Res"},{"key":"13_CR53","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1002\/1097-0142(19870101)59:1<15::AID-CNCR2820590107>3.0.CO;2-Q","volume":"59","author":"MR Posner","year":"1987","unstructured":"Posner MR, Ferrari L, Belliveau JF, et al. A phase I trial of continuous infusion cisplatin. Cancer. 1987;59:15 18.","journal-title":"Cancer"},{"key":"13_CR54","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1007\/s002280100319","volume":"57","author":"B Erdlenbruch","year":"2001","unstructured":"Erdlenbruch B, Nier M, Kern W, et al. Pharmacokinetics of cisplatin and relation to nephrotoxicity in paediatric patients. Eur J Clin Pharmacol. 2001;57:393 402.","journal-title":"Eur J Clin Pharmacol"},{"key":"13_CR55","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1111\/j.1749-6632.1999.tb00278.x","volume":"884","author":"HD. Humes","year":"1999","unstructured":"Humes HD. Insights into ototoxicity. Analogies to nephrotoxicity. Ann N Y Acad Sci. 1999;884:15 18.","journal-title":"Ann N Y Acad Sci"},{"key":"13_CR56","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1200\/JCO.1989.7.1.100","volume":"7","author":"C Dominici","year":"1989","unstructured":"Dominici C, Petrucci F, Caroli S, et al. A pharmacokinetic study of high-dose continuous infusion cisplatin in children with solid tumors. J Clin Oncol. 1989;7:100 107.","journal-title":"J Clin Oncol"},{"key":"13_CR57","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1089\/sct.1990.6.145","volume":"6","author":"T Murakami","year":"1990","unstructured":"Murakami T, Inoue S, Sasaki K, et al. Studies on age-dependent plasma platinum pharmacokinetics and ototoxicity of cisplatin. Sel Cancer Ther. 1990;6:145 151.","journal-title":"Sel Cancer Ther"},{"key":"13_CR58","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1097\/01.mph.0000199586.98926.8e","volume":"28","author":"AA Gupta","year":"2006","unstructured":"Gupta AA, Capra M, Papaioannou V, et al. Low incidence of ototoxicity with continuous infusion of cisplatin in the treatment of pediatric germ cell tumors. J Pediatr Hematol Oncol. 2006;28:91 94.","journal-title":"J Pediatr Hematol Oncol"},{"key":"13_CR59","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1002\/pbc.20673","volume":"47","author":"C Lanvers-Kaminsky","year":"2006","unstructured":"Lanvers-Kaminsky C, Krefeld B, Dinnesen AG, et al. Continuous or repeated prolonged cisplatin infusions in children: a prospective study on ototoxicity, platinum concentrations, and standard serum parameters. Pediatr Blood Cancer. 2006;47:183 193.","journal-title":"Pediatr Blood Cancer"},{"key":"13_CR60","doi-asserted-by":"crossref","first-page":"708","DOI":"10.1200\/JCO.2006.08.9599","volume":"25","author":"J Oldenburg","year":"2007","unstructured":"Oldenburg J, Kraggerud SM, Cvancarova M, et al. Cisplatin-induced long-term hearing impairment is associated with specific glutathione s-transferase genotypes in testicular cancer survivors. J Clin Oncol. 2007;25:708 714.","journal-title":"J Clin Oncol"},{"key":"13_CR61","doi-asserted-by":"crossref","first-page":"639","DOI":"10.1097\/00001813-200009000-00007","volume":"11","author":"U Peters","year":"2000","unstructured":"Peters U, Preisler-Adams S, Hebeisen A, et al. Glutathione S-transferase genetic polymorphisms and individual sensitivity to the ototoxic effect of cisplatin. Anticancer Drugs. 2000;11:639 643.","journal-title":"Anticancer Drugs"},{"key":"13_CR62","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1097\/00005537-199703000-00029","volume":"107","author":"S Kohn","year":"1997","unstructured":"Kohn S, Fradis M, Podoshin L, et al. Ototoxicity resulting from combined administration of cisplatin and gentamicin. Laryngoscope. 1997;107:407 408.","journal-title":"Laryngoscope"},{"key":"13_CR63","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1097\/MPH.0b013e318059c220","volume":"29","author":"PP Coradini","year":"2007","unstructured":"Coradini PP, Cigana L, Selistre SG, et al. Ototoxicity from cisplatin therapy in childhood cancer. J Pediatr Hematol Oncol. 2007;29:355 360.","journal-title":"J Pediatr Hematol Oncol"},{"key":"13_CR64","first-page":"35","volume":"13","author":"RJ Hallmark","year":"1992","unstructured":"Hallmark RJ, Snyder JM, Jusenius K, et al. Factors influencing ototoxicity in ovarian cancer patients treated with Cis-platinum based chemotherapy. Eur J Gynaecol Oncol. 1992;13:35 44.","journal-title":"Eur J Gynaecol Oncol"},{"key":"13_CR65","first-page":"282","volume-title":"Pathology of Neoplasia in Children and Adults","author":"DL Gaegcnti","year":"1986","unstructured":"Gaegcnti DL. Childhood. In: Finegold M, Beningtion J, eds. Pathology of Neoplasia in Children and Adults. Philadelphia: WB Saunders. 1986:282 312."},{"key":"13_CR66","doi-asserted-by":"crossref","first-page":"145","DOI":"10.3109\/08880019009033384","volume":"7","author":"C Buhrer","year":"1990","unstructured":"Buhrer C, Weinel P, Sauter S, et al. Acute onset deafness in a 4 year-old girl after a single infusion of cis-platinum. Pediatr Hematol Oncol. 1990;7:145 148.","journal-title":"Pediatr Hematol Oncol"},{"key":"13_CR67","doi-asserted-by":"crossref","first-page":"1806","DOI":"10.1097\/00005537-199911000-00016","volume":"109","author":"AL Berg","year":"1999","unstructured":"Berg AL, Spitzer JB, Garvin JH, Jr. Ototoxic impact of cisplatin in pediatric oncology patients. Laryngoscope. 1999;109:1806 1814.","journal-title":"Laryngoscope"},{"key":"13_CR68","doi-asserted-by":"crossref","first-page":"2352","DOI":"10.1016\/j.ejca.2004.08.002","volume":"40","author":"R. Skinner","year":"2004","unstructured":"Skinner R. Best practice in assessing ototoxicity in children with cancer. Eur J Cancer. 2004;40:2352 2354.","journal-title":"Eur J Cancer"},{"key":"13_CR69","volume-title":"Hearing in Children","author":"JL Northern","year":"1991","unstructured":"Northern JL, Downs MP. Hearing in Children, ed. Baltimore, MD: Williams & Wilkins, 1991"},{"issue":"Suppl 12","key":"13_CR70","first-page":"11","volume":"35","author":"American Speech-Language-Hearing Association.","year":"2004","unstructured":"American Speech-Language-Hearing Association. Guidelines for the audiologic management of individuals receiving cochleotoxic drug therapy. ASHA. 2004;35(Suppl 12):11 19.","journal-title":"ASHA"},{"key":"13_CR71","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1097\/00003446-199810000-00001","volume":"19","author":"FH Bess","year":"1998","unstructured":"Bess FH, Dodd-Murphy J, Parker RA. Children with minimal sensorineural hearing loss: prevalence, educational performance, and functional status. Ear Hear. 1998;19:339 354.","journal-title":"Ear Hear"},{"issue":"4","key":"13_CR72","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1007\/s00106-005-1368-1","volume":"55","author":"CM Schmidt","year":"2007","unstructured":"Schmidt CM, Bartholom\u00e4us E, Deuster D, et al. The Muenster classification of high frequency hearing loss following cisplatin chemotherapy. HNO 2007;55(4):299 306.","journal-title":"HNO"},{"key":"13_CR73","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/S0165-5876(01)00455-4","volume":"59","author":"P Stavroulaki","year":"2001","unstructured":"Stavroulaki P, Apostolopoulos N, Segas J, et al. Evoked otoacoustic emissions an approach for monitoring cisplatin induced ototoxicity in children. Int J Pediatr Otorhinolaryngol. 2001;59:47 57.","journal-title":"Int J Pediatr Otorhinolaryngol"},{"key":"13_CR74","first-page":"257","volume":"9","author":"TA Littman","year":"1998","unstructured":"Littman TA, Magruder A, Strother DR. Monitoring and predicting ototoxic damage using distortion-product otoacoustic emissions: pediatric case study. J Am Acad Audiol. 1998;9:257 262.","journal-title":"J Am Acad Audiol"},{"key":"13_CR75","unstructured":"Smith LJ, inventor Smith, L J (SMIT-Individual), assignee. Educational kit used for teaching paleontology to child. US. 1999 August 24."},{"key":"13_CR76","first-page":"521","volume":"21","author":"R Sockalingam","year":"2000","unstructured":"Sockalingam R, Freeman S, Cherny TL, et al. Effect of high-dose cisplatin on auditory brainstem responses and otoacoustic emissions in laboratory animals. Am J Otol. 2000;21:521 527.","journal-title":"Am J Otol"},{"key":"13_CR77","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1016\/S0188-4409(03)00022-5","volume":"34","author":"RM Toral","year":"2003","unstructured":"Toral RM, Skurovitch-Bialik P, Collado-Corona MA, et al. Distortion product otoacoustic emissions test is useful in children undergoing cisplatin treatment. Arch Med Res. 2003;34:205 208.","journal-title":"Arch Med Res"},{"key":"13_CR78","doi-asserted-by":"crossref","first-page":"1130","DOI":"10.1288\/00005537-199409000-00014","volume":"104","author":"MA Hotz","year":"1994","unstructured":"Hotz MA, Harris FP, Probst R. Otoacoustic emissions: an approach for monitoring aminoglycoside-induced ototoxicity. Laryngoscope. 1994;104:1130 1134.","journal-title":"Laryngoscope"},{"key":"13_CR79","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1016\/0378-5955(94)90188-0","volume":"74","author":"M Subramaniam","year":"1994","unstructured":"Subramaniam M, Salvi RJ, Spongr VP, et al. Changes in distortion product otoacoustic emissions and outer hair cells following interrupted noise exposures. Hear Res. 1994;74:204 216.","journal-title":"Hear Res"},{"key":"13_CR80","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1080\/14992020600582117","volume":"45","author":"I Dhooge","year":"2006","unstructured":"Dhooge I, Dhooge C, Geukens S, et al. Distortion product otoacoustic emissions: an objective technique for the screening of hearing loss in children treated with platin derivatives. Int J Audiol. 2006;45:337 343.","journal-title":"Int J Audiol"},{"key":"13_CR81","doi-asserted-by":"crossref","first-page":"157","DOI":"10.3766\/jaaa.14.3.2","volume":"14","author":"KC Campbell","year":"2003","unstructured":"Campbell KC, Kelly E, Targovnik N, et al. Audiologic monitoring for potential ototoxicity in a phase I clinical trial of a new glycopeptide antibiotic. J Am Acad Audiol. 2003;14:157 168; quiz 70 71.","journal-title":"J Am Acad Audiol"},{"key":"13_CR82","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1053\/hn.1999.v121.a101567","volume":"121","author":"BD Ress","year":"1999","unstructured":"Ress BD, Sridhar KS, Balkany TJ, et al. Effects of cis-platinum chemotherapy on otoacoustic emissions: the development of an objective screening protocol. Third place Resident Clinical Science Award. 1998. Otolaryngol Head Neck Surg. 1999;121:693 701.","journal-title":"Otolaryngol Head Neck Surg"},{"key":"13_CR83","doi-asserted-by":"crossref","first-page":"1190","DOI":"10.1200\/JCO.2006.07.9723","volume":"25","author":"KR Knight","year":"2007","unstructured":"Knight KR, Kraemer DF, Winter C, et al. Early changes in auditory function as a result of platinum chemotherapy: use of extended high-frequency audiometry and evoked distortion product otoacoustic emissions. J Clin Oncol. 2007;25:1190 1195.","journal-title":"J Clin Oncol"},{"key":"13_CR84","unstructured":"A. B. Room acoustics and speech perception. http:\/\/wwwwrohansdsuedu\/aboothro\/files\/RoomAcoustics\/Roomacousticsandspeechperceptionpdf , 2002."},{"key":"13_CR85","doi-asserted-by":"crossref","first-page":"556","DOI":"10.1001\/archotol.130.5.556","volume":"130","author":"PG Stelmachowicz","year":"2004","unstructured":"Stelmachowicz PG, Pittman AL, Hoover BM, et al. The importance of high-frequency audibility in the speech and language development of children with hearing loss. Arch Otolaryngol Head Neck Surg. 2004;130:556 562.","journal-title":"Arch Otolaryngol Head Neck Surg"},{"key":"13_CR86","doi-asserted-by":"crossref","first-page":"2183","DOI":"10.1121\/1.1400757","volume":"110","author":"PG Stelmachowicz","year":"2001","unstructured":"Stelmachowicz PG, Pittman AL, Hoover BM, et al. Effect of stimulus bandwidth on the perception of \/s\/ in normal- and hearing-impaired children and adults. J Acoust Soc Am. 2001;110:2183 2190.","journal-title":"J Acoust Soc Am"},{"key":"13_CR87","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1121\/1.1916407","volume":"19","author":"NR French","year":"1947","unstructured":"French NR, Steinberg J. Factors governing the intelligibility of speech sounds. J Acoust Soc Am. 1947;19:90 119.","journal-title":"J Acoust Soc Am"},{"key":"13_CR88","volume-title":"Introduction to the Handicap of Hearing Impairment: Auditory Impairment Versus Hearing Handicap","author":"J WT Katz","year":"1982","unstructured":"Katz J WT. Introduction to the Handicap of Hearing Impairment: Auditory Impairment Versus Hearing Handicap.San Diego, CA: Singular Publishing Group; 1982."},{"key":"13_CR89","first-page":"3641","volume":"48","author":"GD Smoluk","year":"1988","unstructured":"Smoluk GD, Fahey RC, Calabro-Jones PM, et al. Radioprotection of cells in culture by WR-2721 and derivatives: form of the drug responsible for protection. Cancer Res. 1988;48:3641 3647.","journal-title":"Cancer Res"},{"key":"13_CR90","first-page":"78","volume":"23","author":"JH. Schiller","year":"1996","unstructured":"Schiller JH. High-dose cisplatin and vinblastine plus amifostine for metastatic non-small cell lung cancer. Semin Oncol. 1996;23:78 82.","journal-title":"Semin Oncol"},{"issue":"4","key":"13_CR91","doi-asserted-by":"crossref","first-page":"S40","DOI":"10.1016\/S0959-8049(96)00316-4","volume":"32","author":"LM. Schuchter","year":"1996","unstructured":"Schuchter LM. Exploration of platinum-based dose-intensive chemotherapy strategies with amifostine (Ethyol). Eur J Cancer. 1996;32A Suppl 4:S40 S42.","journal-title":"Eur J Cancer"},{"key":"13_CR92","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1038\/sj.bjc.6690404","volume":"80","author":"GA Hospers","year":"1999","unstructured":"Hospers GA, Eisenhauer EA, de Vries EG. The sulfhydryl containing compounds WR-2721 and glutathione as radio- and chemoprotective agents. A review, indications for use and prospects. Br J Cancer. 1999;80:629 638.","journal-title":"Br J Cancer"},{"key":"13_CR93","first-page":"325","volume":"4","author":"GC. Block KI","year":"2005","unstructured":"Block KI GC. Commentary: the pharmacological antioxidant amifostine implications of recent research for integrative cancer care. Integrative Cancer Therapies. 2005;4:325 351.","journal-title":"Integrative Cancer Therapies"},{"key":"13_CR94","doi-asserted-by":"crossref","first-page":"294","DOI":"10.2310\/7070.2003.11264","volume":"32","author":"AE Hussain","year":"2003","unstructured":"Hussain AE, Blakley BW, Nicolas M, et al. Assessment of the protective effects of amifostine against cisplatin-induced toxicity. J Otolaryngol. 2003;32:294 297.","journal-title":"J Otolaryngol"},{"key":"13_CR95","doi-asserted-by":"crossref","first-page":"1660","DOI":"10.1097\/00005537-200409000-00030","volume":"114","author":"A Ekborn","year":"2004","unstructured":"Ekborn A, Hansson J, Ehrsson H, et al. High-dose Cisplatin with amifostine: ototoxicity and pharmacokinetics. Laryngoscope. 2004;114:1660 1667.","journal-title":"Laryngoscope"},{"key":"13_CR96","doi-asserted-by":"crossref","first-page":"841","DOI":"10.1002\/cncr.21218","volume":"104","author":"N Marina","year":"2005","unstructured":"Marina N, Chang KW, Malogolowkin M, et al. Amifostine does not protect against the ototoxicity of high-dose cisplatin combined with etoposide and bleomycin in pediatric germ-cell tumors: a Children's Oncology Group study. Cancer. 2005;104:841 847.","journal-title":"Cancer"},{"key":"13_CR97","first-page":"2","volume":"23","author":"R. Capizzi","year":"1996","unstructured":"Capizzi R. Amifostine: the preclinical basis for broad-spectrum selective cytoprotection of normal tissues from cytotoxic therapies. Semin Oncol. 1996;23:2 17.","journal-title":"Semin Oncol"},{"key":"13_CR98","first-page":"706","volume":"56","author":"EA Neuwelt","year":"1996","unstructured":"Neuwelt EA, Brummett RE, Remsen LG, et al. In vitro and animal studies of sodium thiosulfate as a potential chemoprotectant against carboplatin-induced ototoxicity. Cancer Res. 1996;56:706 709.","journal-title":"Cancer Res"},{"key":"13_CR99","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/S0022-3565(24)37559-7","volume":"286","author":"EA Neuwelt","year":"1998","unstructured":"Neuwelt EA, Brummett RE, Doolittle ND, et al. First evidence of otoprotection against carboplatin-induced hearing loss with a two-compartment system in patients with central nervous system malignancy using sodium thiosulfate. J Pharmacol Exp Ther. 1998;286:77 84.","journal-title":"J Pharmacol Exp Ther"},{"key":"13_CR100","first-page":"98","volume":"18","author":"R Abe","year":"1986","unstructured":"Abe R, Akiyoshi T, Tsuji H, et al. Protection of antiproliferative effect of cis-diamminedichloroplatinum (II) by sodium thiosulfate. Cancer Chemother Pharmacol. 1986;18:98 100.","journal-title":"Cancer Chemother Pharmacol"},{"key":"13_CR101","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1093\/clinchem\/32.4.641","volume":"32","author":"F Elferink","year":"1986","unstructured":"Elferink F, van der Vijgh WJ, Klein I, et al. Interaction of cisplatin and carboplatin with sodium thiosulfate: reaction rates and protein binding. Clin Chem. 1986;32:641 645.","journal-title":"Clin Chem"},{"key":"13_CR102","doi-asserted-by":"crossref","first-page":"1052","DOI":"10.1124\/jpet.105.087601","volume":"314","author":"DT Dickey","year":"2005","unstructured":"Dickey DT, Wu YJ, Muldoon LL, et al. Protection against cisplatin-induced toxicities by N-acetylcysteine and sodium thiosulfate as assessed at the molecular, cellular, and in vivo levels. J Pharmacol Exp Ther. 2005;314:1052 1058.","journal-title":"J Pharmacol Exp Ther"},{"key":"13_CR103","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1016\/S0378-5955(96)00152-9","volume":"102","author":"KC Campbell","year":"1996","unstructured":"Campbell KC, Rybak LP, Meech RP, et al. D-methionine provides excellent protection from cisplatin ototoxicity in the rat. Hear Res. 1996;102:90 98.","journal-title":"Hear Res"},{"key":"13_CR104","first-page":"731","volume":"20","author":"D Reser","year":"1999","unstructured":"Reser D, Rho M, Dewan D, et al. L- and D- methionine provide equivalent long term protection against CDDP-induced ototoxicity in vivo, with partial in vitro and in vivo retention of antineoplastic activity. Neurotoxicology. 1999;20:731 748.","journal-title":"Neurotoxicology"},{"key":"13_CR105","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1067\/mhn.2002.125299","volume":"126","author":"KD Korver","year":"2002","unstructured":"Korver KD, Rybak LP, Whitworth C, et al. Round window application of D-methionine provides complete cisplatin otoprotection. Otolaryngol Head Neck Surg. 2002;126:683 689.","journal-title":"Otolaryngol Head Neck Surg"},{"key":"13_CR106","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/S0378-5955(99)00142-2","volume":"138","author":"KC Campbell","year":"1999","unstructured":"Campbell KC, Meech RP, Rybak LP, et al. D-Methionine protects against cisplatin damage to the stria vascularis. Hear Res. 1999;138:13 28.","journal-title":"Hear Res"},{"key":"13_CR107","unstructured":"Sequoia Ecosystem and Recreation Preserve Act of 1999. In. 106th Congress ed; 1999."},{"key":"13_CR108","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1097\/00129492-200401000-00007","volume":"25","author":"C Wimmer","year":"2004","unstructured":"Wimmer C, Mees K, Stumpf P, et al. Round window application of D-methionine, sodium thiosulfate, brain-derived neurotrophic factor, and fibroblast growth factor-2 in cisplatin-induced ototoxicity. Otol Neurotol. 2004;25:33 40.","journal-title":"Otol Neurotol"},{"key":"13_CR109","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1016\/0378-5955(95)00066-D","volume":"86","author":"MW Church","year":"1995","unstructured":"Church MW, Kaltenbach JA, Blakley BW, et al. The comparative effects of sodium thiosulfate, diethyldithiocarbamate, fosfomycin and WR-2721 on ameliorating cisplatin-induced ototoxicity. Hear Res. 1995;86:195 203.","journal-title":"Hear Res"},{"key":"13_CR110","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1016\/S0194-5998(97)70020-2","volume":"117","author":"JA Kaltenbach","year":"1997","unstructured":"Kaltenbach JA, Church MW, Blakley BW, et al. Comparison of five agents in protecting the cochlea against the ototoxic effects of cisplatin in the hamster. Otolaryngol Head Neck Surg. 1997;117:493 500.","journal-title":"Otolaryngol Head Neck Surg"},{"key":"13_CR111","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1146\/annurev.med.55.091902.105251","volume":"55","author":"BJ Copeland","year":"2004","unstructured":"Copeland BJ, Pillsbury HC, 3rd. Cochlear implantation for the treatment of deafness. Annu Rev Med. 2004;55:157 167.","journal-title":"Annu Rev Med"},{"key":"13_CR112","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1002\/mpo.2950160517","volume":"16","author":"P Brock","year":"1988","unstructured":"Brock P, Pritchard J, Bellman S, Pinkerton CR. Ototoxicity of high-dose cisplatinum in children. Med Pediatr Oncol.1988;16:368 369.","journal-title":"Med Pediatr Oncol"},{"key":"13_CR113","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1038\/bjc.1991.35","volume":"63","author":"P Brock","year":"1991","unstructured":"Brock P, Bellman S, Pritchard J. Ototoxicity of cisplatinum Br J Cancer.1991;63:159 161.","journal-title":"Br J Cancer"},{"key":"13_CR114","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1002\/mpo.2950190415","volume":"19","author":"PR Brock","year":"1991","unstructured":"Brock PR, Bellman SC, Yeomans EC, Pinkerton CR, Pritchard J. Cisplatin ototoxicity in children; a practical grading system. Med Pediatr Oncol.1991;19:295 300.","journal-title":"Med Pediatr Oncol"},{"key":"13_CR115","first-page":"S36","volume":"66:Suppl XVIII","author":"P Brock","year":"1992","unstructured":"Brock P, Yeomans E, Bellman S, Pritchard J. Cisplatin therapy in infants: short and long-term morbidity. Br J Cancer. 1992;66:Suppl XVIII:S36 S40.","journal-title":"Br J Cancer"}],"container-title":["Cancer Treatment and Research","Late Effects of Treatment for Brain Tumors"],"original-title":[],"link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/b109924_13.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,2,12]],"date-time":"2025-02-12T19:42:06Z","timestamp":1739389326000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/b109924_13"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009]]},"ISBN":["9780387771021","9780387771038"],"references-count":115,"URL":"https:\/\/doi.org\/10.1007\/b109924_13","relation":{},"ISSN":["0927-3042"],"issn-type":[{"value":"0927-3042","type":"print"}],"subject":[],"published":{"date-parts":[[2009]]}}}