{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,17]],"date-time":"2025-12-17T08:34:30Z","timestamp":1765960470890},"reference-count":34,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[1990,8,1]],"date-time":"1990-08-01T00:00:00Z","timestamp":649468800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Naunyn-Schmiedeberg's Arch Pharmacol"],"published-print":{"date-parts":[[1990,8]]},"DOI":"10.1007\/bf00166960","type":"journal-article","created":{"date-parts":[[2004,11,6]],"date-time":"2004-11-06T05:52:23Z","timestamp":1099720343000},"page":"171-176","source":"Crossref","is-referenced-by-count":57,"title":["Central, naloxone-reversible antinociception by diclofenac in the rat"],"prefix":"10.1007","volume":"342","author":[{"given":"R.","family":"Bj\ufffdrkman","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Hedner","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T.","family":"Hedner","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Henning","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"CR1","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1016\/0304-3959(86)90161-2","volume":"27","author":"KH Carlsson","year":"1986","unstructured":"Carlsson KH, Helmreich J, Jurna I (1986) Activation of inhibition from periaqueductal grey matter mediates central analgesic effect of metamizol (Dipyrone). Pain 27:373?390","journal-title":"Pain"},{"key":"CR2","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1016\/0304-3959(88)90043-7","volume":"32","author":"KH Carlsson","year":"1988","unstructured":"Carlsson KH, Monzel W and Jurna I (1988) Depression by morphine and the non-opioid analgesic agents metamizol (Dipyrone), lysine acetylate and paracetamol, of activity in rat thalamus neurons evoked by electrical stimulation of nociceptive afferents. Pain 32:313?326","journal-title":"Pain"},{"key":"CR3","first-page":"74","volume":"72","author":"FE D'Amour","year":"1941","unstructured":"D'Amour FE, Smith DL (1941) A method for determining loss of pain sensation. J Pharm Exp Ther 72:74?79","journal-title":"J Pharm Exp Ther"},{"key":"CR4","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/0014-2999(80)90377-5","volume":"61","author":"R Deraedt","year":"1980","unstructured":"Deraedt R, Jonquey S, Delevall\u00e9e F, Flahaut M (1980) Release of ] prostaglandins E and F in an algogenic reaction and its inhibition. Eur J Pharmacol 61:17?24","journal-title":"Eur J Pharmacol"},{"key":"CR5","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/0014-2999(78)90265-0","volume":"53","author":"SH Ferreira","year":"1978","unstructured":"Ferreira SH, Lorenzetti BB, Corr\u00e9a FMA (1978) Central and peripheral antialgesic action of aspirin-like drugs. Eur J Pharmacol 53:39?48","journal-title":"Eur J Pharmacol"},{"key":"CR6","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1111\/j.2042-7158.1978.tb13342.x","volume":"30","author":"JA Garcia-Sevilla","year":"1978","unstructured":"Garcia-Sevilla JA, Ahtee L, Magnusson T, Carlsson A (1978) Opiate-receptor mediated changes in monoamine synthesis in rat brain. J Pharm Pharmcol 30:613?621","journal-title":"J Pharm Pharmcol"},{"key":"CR7","first-page":"459","volume":"66","author":"G Gerra","year":"1985","unstructured":"Gerra G, Ceresini, Rastelli G, Butturini L, Vescovi PP (1985) Effect of diclofenac on the opiate withdrawal syndrome. G Clin Med 66:459?465","journal-title":"G Clin Med"},{"key":"CR8","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/0014-2999(73)90115-5","volume":"24","author":"W Grossmann","year":"1973","unstructured":"Grossmann W, Jurna I, Nell T, Theres C (1973) The dependence of the anti-nociceptive effect of morphine and other analgesic agents on spinal motor activity after central monoamine depletion. Eur J Pharmacol 24:67?77","journal-title":"Eur J Pharmacol"},{"key":"CR9","first-page":"237","volume":"125","author":"LC Hendershot","year":"1959","unstructured":"Hendershot LC, Forsaith J (1959) Antagonism of the frequency of phenylquinone-induced writhing in the mouse by weak analgesics and nonanalgesics. J Pharmacol Exp Ther 125:237?240","journal-title":"J Pharmacol Exp Ther"},{"key":"CR10","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1007\/BF00508784","volume":"334","author":"M Holmgren","year":"1986","unstructured":"Holmgren M, Hedner J, Mellstrand T, Nordberg G, Hedner T (1986) Characterization of the antinociceptive effects of some adenosine analogues in the rat. Naunyn-Schmiedeberg's Arch Pharmacol 334:290?293","journal-title":"Naunyn-Schmiedeberg's Arch Pharmacol"},{"key":"CR11","first-page":"1698","volume":"27","author":"R Jaques","year":"1977","unstructured":"Jaques R (1977) Antagonism of non-steroidal anti-inflammatory drugs and narcotic analgesics against etacrynic acid induced writhing. Arzneimittel Forschung 27:1698?1700","journal-title":"Arzneimittel Forschung"},{"key":"CR12","first-page":"119","volume-title":"Manifestations of pain in analgesic evaluation in animals and man","author":"RKS Lim","year":"1968","unstructured":"Lim RKS, Guzman F (1968) Manifestations of pain in analgesic evaluation in animals and man. Academic Press, London, pp 119?152"},{"key":"CR13","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1016\/0031-9384(81)90350-4","volume":"27","author":"RM Lopachin","year":"1981","unstructured":"Lopachin RM, Rudy TA, Yaksh TL (1981) An improved method for chronic catheterization of the rat spinal subarachnoid space. Physiol Behav 27:559?561","journal-title":"Physiol Behav"},{"key":"CR14","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1177\/030006058401200205","volume":"12","author":"A Martini","year":"1984","unstructured":"Martini A, Bondiolotti GP, Sacerdote P, Pierro L, Picotti GB, Panerai AE, Restelli L, Zancaner F, Monza G (1984) Diclofenac increases B-endorphin plasma concentrations. J Int Med Res 12:92?95","journal-title":"J Int Med Res"},{"key":"CR15","first-page":"181","volume":"4","author":"AD Martorano","year":"1984","unstructured":"Martorano AD, Di Chiara A, Speciale R, Palermo R, Luciano A, Di Stefano S (1984) Trattamento con diclofenac sodico nel dolore post-operatoria e oppioidi endogeni. Argomenti Di Chirurgia 4:181?187","journal-title":"Argomenti Di Chirurgia"},{"key":"CR16","doi-asserted-by":"crossref","first-page":"5","DOI":"10.3109\/03009747809097211","volume":"22","author":"R Menass\u00e9","year":"1978","unstructured":"Menass\u00e9 R, Hedwall PR, Kraetz J, Pericin C, Riesterer L, Sallmann A, Ziel R, Jaques R (1978) Pharmacological properties of diclofenac sodium and its metabolites. Scand J Rheumatol Suppl 22:5?16","journal-title":"Scand J Rheumatol Suppl"},{"key":"CR17","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1016\/0006-8993(88)91555-7","volume":"450","author":"TJ Ness","year":"1988","unstructured":"Ness TJ, Gebhart GF (1988) Colorectal distension as a noxious visceral stimulus: physiologic and pharmacologic characterization of pseudoaffective reflexes in the rat. Brain Res 450:153?169","journal-title":"Brain Res"},{"key":"CR18","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1254\/jjp.35.95","volume":"35","author":"S Okuyama","year":"1984","unstructured":"Okuyama S, Aihara H (1984) The mode of action of analgesic drugs in adjuvant arthritic rats as an experimental model of chronic inflammatory pain: Possible central analgesic action of acidic nonsteroidal anti-inflammatory drugs. Jpn J Pharmacol 35:95?103","journal-title":"Jpn J Pharmacol"},{"key":"CR19","doi-asserted-by":"crossref","first-page":"902","DOI":"10.1248\/bpb1978.9.902","volume":"9","author":"S Okuyama","year":"1986","unstructured":"Okuyama S, Aihara H (1986) Hyperalgesic action in mice of intracerebroventricularly administered arachidonic acid, PGE2, PGF2a and PGD2: Effects of analgesic drugs on hyperalgesia. J Pharmacobiodyn 9:902?908","journal-title":"J Pharmacobiodyn"},{"key":"CR20","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1016\/0031-6989(85)90085-2","volume":"17","author":"P Sacerdote","year":"1985","unstructured":"Sacerdote P, Monza G, Mantegazza P, Panerai AE (1985) Diclofenac and pirprofen modify pituitary and hypothalamic beta-endorphin concentrations. Pharmacol Res Commun 17:679?684","journal-title":"Pharmacol Res Commun"},{"key":"CR21","unstructured":"Shaligram SV, Nabar SD (1987) Sites of anti-writhing effect of salicylate. Xth Internat Congr Pharm, Sydney, Australia, poster 825"},{"key":"CR22","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1016\/0014-4886(84)90014-1","volume":"84","author":"KW Shyu","year":"1984","unstructured":"Shyu KW, Lin MT, Wu TC (1984) Possible role of central serotonergic neurons: in the development of dental pain and aspirin-induced analgesia in the monkey. Exp Neurol 84:179?187","journal-title":"Exp Neurol"},{"key":"CR23","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1007\/BF01252242","volume":"62","author":"KW Shyu","year":"1985","unstructured":"Shyu KW, Lin MT (1985) Hypothalamic monoaminergic mechanisms of aspirin-induced analgesia in monkeys. J Neural Transm 62:285?293","journal-title":"J Neural Transm"},{"key":"CR24","doi-asserted-by":"crossref","first-page":"729","DOI":"10.3181\/00379727-95-23345","volume":"95","author":"E Siegmund","year":"1957","unstructured":"Siegmund E, Cadmus R, Lu G (1957a) A method for evaluating both non-narcotic and narcotic analgesics. Proc Soc Exp Biol Med 95:729?731","journal-title":"Proc Soc Exp Biol Med"},{"key":"CR25","first-page":"184","volume":"119","author":"E Siegmund","year":"1957","unstructured":"Siegmund E, Cadmus R, Lu G (1957b) Screening of analgesics, including aspirin-type compounds, based upon the antagonism of chemically induced ?writhing? in mice. J Pharmacol Exp Ther 119:184","journal-title":"J Pharmacol Exp Ther"},{"key":"CR26","first-page":"779","volume":"36","author":"RJ Stephens","year":"1984","unstructured":"Stephens RJ (1984) Evidence for a pharmacokinetic interaction between ibuprofen and meptazinol in the mouse. J Pharmacol Exp Ther 36:779?781","journal-title":"J Pharmacol Exp Ther"},{"key":"CR27","first-page":"151","volume":"1","author":"P Vescovi","year":"1987","unstructured":"Vescovi P, Passeri M, Gerra G, Grossi E (1987) Naloxone inhibits the early phase of diclofenac analgesia in man. The Pain Clinic 1:151?155","journal-title":"The Pain Clinic"},{"key":"CR28","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/0304-3959(89)90065-1","volume":"38","author":"J-C Willer","year":"1989","unstructured":"Willer J-C, De Broucker T, Bussel B, Roby-Brami A, Harrewyn J-M (1989) Central analgesic effect of ketoprofen in humans: electrophysiological evidence for a supraspinal mechanism in a double-blind and cross-over study. Pain 38:1?7","journal-title":"Pain"},{"key":"CR29","first-page":"300","volume":"80","author":"G Woolfe","year":"1944","unstructured":"Woolfe G, MacDonald AD (1944) The evaluation of analgesic action of pethidine hydrochloride (Demerol). J Pharmacol Exp Ther 80:300?307","journal-title":"J Pharmacol Exp Ther"},{"key":"CR30","first-page":"178","volume-title":"Textbook of pain","author":"L Vyklicky","year":"1984","unstructured":"Vyklicky L (1984) Methods of testing pain mechanisms in animals. In: Wall PD, Melzack R (eds) Textbook of pain. Churchill Livingstone, Edinburgh London; Raven Press, New York, pp 178?185"},{"key":"CR31","doi-asserted-by":"crossref","first-page":"1031","DOI":"10.1016\/0031-9384(76)90029-9","volume":"17","author":"TL Yaksh","year":"1976","unstructured":"Yaksh TL (1976) Chronic catheterization of the spinal subarachnoid space. Physiol Behav 17:1031?1036","journal-title":"Physiol Behav"},{"key":"CR32","first-page":"137","volume-title":"Central and peripheral mechanisms for the antialgesic action of acetylsalicylic acid","author":"TL Yaksh","year":"1982","unstructured":"Yaksh TL (1982) Central and peripheral mechanisms for the antialgesic action of acetylsalicylic acid. Raven Press, New York, pp 137?151"},{"key":"CR33","first-page":"171","volume":"25","author":"TL Yaksh","year":"1984","unstructured":"Yaksh TL (1984a) Multiple opioid receptor systems in brain and spinal cord. Part I. Eur J Anaesthesiol 25:171?199","journal-title":"Eur J Anaesthesiol"},{"key":"CR34","first-page":"201","volume":"21","author":"TL Yaksh","year":"1984","unstructured":"Yaksh TL (1984b) Multiple opioid receptor systems in brain and spinal cord. Part 2. Eur J Anaesthesiol 21:201?243","journal-title":"Eur J Anaesthesiol"}],"container-title":["Naunyn-Schmiedeberg's Archives of Pharmacology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/article\/10.1007\/BF00166960\/fulltext.html","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF00166960.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/BF00166960\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF00166960","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,4,8]],"date-time":"2019-04-08T16:35:03Z","timestamp":1554741303000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/BF00166960"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1990,8]]},"references-count":34,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1990,8]]}},"alternative-id":["BF00166960"],"URL":"https:\/\/doi.org\/10.1007\/bf00166960","relation":{},"ISSN":["0028-1298","1432-1912"],"issn-type":[{"value":"0028-1298","type":"print"},{"value":"1432-1912","type":"electronic"}],"subject":[],"published":{"date-parts":[[1990,8]]}}}