{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T03:46:31Z","timestamp":1791085591587,"version":"4.1.0"},"reference-count":26,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[1991,8,1]],"date-time":"1991-08-01T00:00:00Z","timestamp":681004800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Naunyn-Schmiedeberg's Arch Pharmacol"],"published-print":{"date-parts":[[1991,8]]},"DOI":"10.1007\/bf00167212","type":"journal-article","created":{"date-parts":[[2004,11,8]],"date-time":"2004-11-08T12:57:16Z","timestamp":1099918636000},"page":"150-159","source":"Crossref","is-referenced-by-count":89,"title":["A 5-HT4-like receptor in human right atrium"],"prefix":"10.1007","volume":"344","author":[{"given":"Alberto J.","family":"Kaumann","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Louise","family":"Sanders","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anthony M.","family":"Brown","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kenneth J.","family":"Murray","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Morris J.","family":"Brown","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"CR1","first-page":"48","volume":"14","author":"O Arunlakshana","year":"1959","unstructured":"Arunlakshana O, Schild HO (1959) Some quantitative uses of drug antagonism. Br J Pharmacol 14:48?58","journal-title":"Br J Pharmacol"},{"key":"CR2","unstructured":"Baxter GS, Clarke DE (1990) Putative 5-HT4 receptors mediate relaxation of rat oesophagus. Proceedings of the 2nd IUPHAR Satellite Meeting on Serotonin, Basel, Switzerland, July 11?13, abstract no. P85"},{"key":"CR3","doi-asserted-by":"crossref","first-page":"755","DOI":"10.1152\/jappl.1965.20.4.755","volume":"20","author":"JR Blinks","year":"1965","unstructured":"Blinks JR (1965) Convenient apparatus for recording contractions of isolated muscle. J Appl Physiol 20:755?757","journal-title":"J Appl Physiol"},{"key":"CR4","first-page":"408","volume":"37","author":"J Bockaert","year":"1990","unstructured":"Bockaert J, Sebben M, Dumuis A (1990a) Pharmacological characterisation of 5-hydroxytryptamine4 (5-HT4) receptors positively coupled to adenylate cyclase in adult guinea pig hippocampal membranes: Effect of substituted benzamide derivatives. Mol Pharmacol 37:408?411","journal-title":"Mol Pharmacol"},{"key":"CR5","unstructured":"Bockaert J, Sebben M, Dumuis A (1990b) Inter-relationship between the interactions of 5-HT and benzamide derivatives on 5-HT4 receptors in brain. Second IUPHAR satellite meeting on serotonin, Basel, Switzerland, July 11?13, abstract 64"},{"key":"CR6","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1016\/0003-2697(76)90527-3","volume":"72","author":"MM Bradford","year":"1976","unstructured":"Bradford MM (1976) A rapid sensitive method for quantification of microgram quantities of protein utilising the principle of protein-dye binding. Anal Biochem 72:248?254","journal-title":"Anal Biochem"},{"key":"CR7","first-page":"1378","volume":"252","author":"DA Craig","year":"1990","unstructured":"Craig DA, Clark DE (1990) Pharmacological characterisation of a neuronal receptor for 5-hydroxytryptamine in guinea pig ileum with properties similar to the 5-hydroxytryptamine4 receptor. J Pharmacol Exp Ther 252:1378?1386","journal-title":"J Pharmacol Exp Ther"},{"key":"CR8","first-page":"880","volume":"34","author":"A Dumuis","year":"1988","unstructured":"Dumuis A, Bouhelal R, Sebben M, Cory R, Bockaert J (1988a) A nonclassical 5-hydroxytryptamine receptor positively coupled with adenylate cyclase in the central nervous system. Mol Pharmacol 34:880?887","journal-title":"Mol Pharmacol"},{"key":"CR9","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/0014-2999(88)90503-1","volume":"146","author":"A Dumuis","year":"1988","unstructured":"Dumuis A, Bouhelal R, Sebben M, Bockaert J (1988b) A 5-HT receptor in the central nervous system positively coupled with adenylate cyclase is antagonized by ICS 205?930. Eur J Pharmacol 146:187?188","journal-title":"Eur J Pharmacol"},{"key":"CR10","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1007\/BF00167041","volume":"340","author":"A Dumuis","year":"1989","unstructured":"Dumuis A, Sebben M, Bockaert J (1989a) The gastrointestinal prokinetic benzamide derivatives are agonists at the non-classical 5-HT receptor (5-HT4) positively coupled to adenylate cyclase in neurons. Naunyn-Schmiedeberg's Arch Pharmacol 340:403?410","journal-title":"Naunyn-Schmiedeberg's Arch Pharmacol"},{"key":"CR11","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1016\/0014-2999(89)90304-X","volume":"162","author":"A Dumuis","year":"1989","unstructured":"Dumuis A, Sebben M, Bockaert J (1989b) BRL 24924: a potent agonist at a non-classical 5-HT receptor positively coupled with adenylate cyclase in colliculi neurons. Eur J Pharmacol 162:381?384","journal-title":"Eur J Pharmacol"},{"key":"CR12","unstructured":"Elswood CJ, Bunce KT, Humphrey PPA (1990) Identification of 5-HT4 receptors in guinea-pig ascending colon. Proceedings of the 2nd IUPHAR Satellite Meeting on Serotonin, Basel, July 11?13, abstract no. P86"},{"key":"CR13","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1007\/BF00498852","volume":"331","author":"E Gille","year":"1985","unstructured":"Gille E, Lemoine H, Ehle B, Kaumann AJ (1985) The affinity of (?)-propranolol for ?1- and ?2-adrenoceptors of human hearts. Differential antagonism of the positive inotropic effects and adenylate cyclase stimulation by (?)-noradrenaline and (?)-adrenaline. Naunyn-Schmiedeberg's Arch Pharmacol 331:60?70","journal-title":"Naunyn-Schmiedeberg's Arch Pharmacol"},{"key":"CR14","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1007\/BF00508086","volume":"273","author":"AJ Kaumann","year":"1972","unstructured":"Kaumann AJ (1972) Potentiation of the effects of isoprenaline and noradrenaline by hydrocortisone in cat heart muscle. Naunyn-Schmiedeberg's Arch Pharmacol 273:134?153","journal-title":"Naunyn-Schmiedeberg's Arch Pharmacol"},{"key":"CR15","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1007\/BF00169055","volume":"342","author":"AJ Kaumann","year":"1990","unstructured":"Kaumann AJ (1990) Piglet sinoatrial 5-HT receptors resemble human atrial 5-HT4-like receptors. Naunyn-Schmiedeberg's Arch Pharmacol 342:619?622","journal-title":"Naunyn-Schmiedeberg's Arch Pharmacol"},{"key":"CR16","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1111\/j.1476-5381.1986.tb11137.x","volume":"89","author":"AJ Kaumann","year":"1986","unstructured":"Kaumann AJ, Lobnig BM (1986) Mode of action of (?)-pindolol on feline and human myocardium. Br J Pharmacol 89:207?218","journal-title":"Br J Pharmacol"},{"key":"CR17","doi-asserted-by":"crossref","unstructured":"Kaumann AJ, Sanders L, Brown AM, Murray KJ, Brown MJ (1989) A receptor for 5-hydroxytryptamine in human atrium. Br J Pharmacol 98:664 P","DOI":"10.1111\/j.1476-5381.1990.tb14108.x"},{"key":"CR18","doi-asserted-by":"crossref","first-page":"879","DOI":"10.1111\/j.1476-5381.1990.tb14108.x","volume":"100","author":"AJ Kaumann","year":"1990","unstructured":"Kaumann AJ, Sanders L, Brown AM, Murray KJ, Brown MJ (1990a) A 5-hydroxytryptamine receptor in human atrium. Br J Pharmacol 100:879?885","journal-title":"Br J Pharmacol"},{"key":"CR19","unstructured":"Kaumann AJ, Sanders L, Brown AM, Murray KJ, Brown MJ (1990b) Human atrial 5-HT receptors: similarity to rodent neuronal 5-HT4 receptors. Br J Pharmacol 100:319 P"},{"key":"CR20","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1007\/978-94-009-1912-9_45","volume-title":"Serotonin: From cell biology to pharmacology and therapeutics","author":"AJ Kaumann","year":"1990","unstructured":"Kaumann AJ, Murray KJ, Brown AM, Frampton JE, Sanders L, Brown MJ (1990c) Heart 5-HT receptors. A novel 5-HT receptor in human atrium. In: Paoletti R, Vanhoutte P, Brunello N, Maggi FM (eds) Serotonin: From cell biology to pharmacology and therapeutics. Kluwers, Dordrecht, Boston, London, pp 347?354"},{"key":"CR21","doi-asserted-by":"crossref","unstructured":"Kaumann AJ, Brown AM, Raval P (1991) Putative 5-HT4-like receptors in piglet left atrium. Br J Pharmacol 102:98 P","DOI":"10.1007\/978-3-7091-9175-0_25"},{"key":"CR22","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1007\/BF00506313","volume":"320","author":"H Lemoine","year":"1982","unstructured":"Lemoine H, Kaumann AJ (1982) A novel analysis of concentration-dependence of partial agonism. Naunyn Schmiedeberg's Arch Pharmacol 320:130?144","journal-title":"Naunyn Schmiedeberg's Arch Pharmacol"},{"key":"CR23","first-page":"518","volume":"198","author":"M Marano","year":"1976","unstructured":"Marano M, Kaumann AJ (1976) On the statistics of drug-receptor constants for partial agonists. J Pharmacol Exp Ther 198:518?525","journal-title":"J Pharmacol Exp Ther"},{"key":"CR24","doi-asserted-by":"crossref","first-page":"703","DOI":"10.1042\/bj2670703","volume":"267","author":"KJ Murray","year":"1990","unstructured":"Murray KJ, England PJ, Lynham JA, Mills D, Schmitz-Pfeiffer C, Reeves ML (1990) Use of a synthetic dodecapeptide (malantide) to measure the cyclic AMP-dependent protein kinase activity ratio in a variety of tissues. Biochem J 267:703?708","journal-title":"Biochem J"},{"key":"CR25","doi-asserted-by":"crossref","first-page":"665","DOI":"10.1111\/j.1476-5381.1990.tb14073.x","volume":"100","author":"CM Villalon","year":"1990","unstructured":"Villalon CM, Den Boer MO, Heiligers JPC, Saxena PR (1990) Mediation of 5-hydroxytryptamine-induced tachycardia in the pig by the putative 5-HT4 receptor. Br J Pharmacol 100:665?667","journal-title":"Br J Pharmacol"},{"key":"CR26","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1111\/j.1476-5381.1991.tb12140.x","volume":"102","author":"CM Villalon","year":"1991","unstructured":"Villalon CM, Den Boer MO, Heiligers JPC, Saxena PR (1991) Further characterization, by use of tryptamine and benzamide derivatives, of the putative 5-HT4 receptor mediating tachycardia in the pig. Br J Pharmacol 102:107?112","journal-title":"Br J Pharmacol"}],"container-title":["Naunyn-Schmiedeberg's Archives of Pharmacology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/article\/10.1007\/BF00167212\/fulltext.html","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF00167212.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/BF00167212\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF00167212","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,30]],"date-time":"2023-04-30T01:28:09Z","timestamp":1682818089000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/BF00167212"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1991,8]]},"references-count":26,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1991,8]]}},"alternative-id":["BF00167212"],"URL":"https:\/\/doi.org\/10.1007\/bf00167212","relation":{},"ISSN":["0028-1298","1432-1912"],"issn-type":[{"value":"0028-1298","type":"print"},{"value":"1432-1912","type":"electronic"}],"subject":[],"published":{"date-parts":[[1991,8]]}}}