{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,23]],"date-time":"2026-06-23T04:02:08Z","timestamp":1782187328444,"version":"3.54.5"},"reference-count":33,"publisher":"Springer Science and Business Media LLC","issue":"S1","license":[{"start":{"date-parts":[[1981,3,1]],"date-time":"1981-03-01T00:00:00Z","timestamp":352252800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diabetologia"],"published-print":{"date-parts":[[1981,3]]},"DOI":"10.1007\/bf00254511","type":"journal-article","created":{"date-parts":[[2004,9,16]],"date-time":"2004-09-16T08:07:13Z","timestamp":1095322033000},"page":"417-425","source":"Crossref","is-referenced-by-count":42,"title":["CNS modulation of pancreatic endocrine function"],"prefix":"10.1007","volume":"20","author":[{"given":"D. A.","family":"Bereiter","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F.","family":"Rohner-Jeanrenaud","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H. -R.","family":"Berthoud","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B.","family":"Jeanrenaud","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[1981,3,1]]},"reference":[{"key":"BF00254511_CR1","first-page":"123","volume":"24","author":"BK Anand","year":"1951","unstructured":"Anand BK, Brobeck JR (1951) Hypothalamic control of food intake in rats and cats. Yale J Biol Med 24: 123\u2013140","journal-title":"Yale J Biol Med"},{"key":"BF00254511_CR2","doi-asserted-by":"publisher","first-page":"455","DOI":"10.1002\/cne.901840303","volume":"184","author":"RM Beckstead","year":"1979","unstructured":"Beckstead RM, Norgren R (1979) An autoradiographic examination of the central distribution of the trigeminal, facial, glossopharyngeal and vagus nerves in the monkey. J Comp Neurol 184: 455\u2013472","journal-title":"J Comp Neurol"},{"key":"BF00254511_CR3","doi-asserted-by":"publisher","first-page":"249","DOI":"10.1016\/0006-8993(79)90557-2","volume":"165","author":"DA Bereiter","year":"1979","unstructured":"Bereiter DA, Jeanrenaud B (1979) Altered neuroanatomical organization in the central nervous system of the genetically obese (ob\/ob) mouse. Brain Res 165: 249\u2013260","journal-title":"Brain Res"},{"key":"BF00254511_CR4","doi-asserted-by":"publisher","first-page":"201","DOI":"10.1016\/S0006-8993(80)80046-1","volume":"202","author":"DA Bereiter","year":"1980","unstructured":"Bereiter DA, Jeanrenaud B (1980) Altered dendritic orientation of hypothalamic neurons from genetically obese (ob\/ob) mice. Brain Res 202: 201\u2013206","journal-title":"Brain Res"},{"key":"BF00254511_CR5","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1152\/ajplegacy.1973.225.2.481","volume":"225","author":"RN Bergman","year":"1973","unstructured":"Bergman RN, Miller RE (1973) Direct enhancement of insulin secretion by vagal stimulation of the isolated pancreas. Am J Physiol 225: 481\u2013486","journal-title":"Am J Physiol"},{"key":"BF00254511_CR6","doi-asserted-by":"publisher","first-page":"183","DOI":"10.1016\/0165-1838(80)90044-2","volume":"2","author":"H-R Berthoud","year":"1980","unstructured":"Berthoud H-R, Bereiter DA, Jeanrenaud B (1980) Role of the autonomic nervous system in the mediation of LHA electrical stimulation \u2014 induced effects on insulinemia and glycemia. J Autonomic Nerv Sys 2: 183\u2013198","journal-title":"J Autonomic Nerv Sys"},{"key":"BF00254511_CR7","doi-asserted-by":"publisher","first-page":"393","DOI":"10.1007\/BF00254508","volume":"20","author":"H-R Berthoud","year":"1981","unstructured":"Berthoud H-R, Bereiter DA, Trimble ER, Siegel EG, Jeanrenaud B (1981) Cephalic phase, reflex insulin secretion: Neuroanatomical and physiological characterization. Diabetologia 20 [Suppl]: 393\u2013401","journal-title":"Diabetologia"},{"key":"BF00254511_CR8","doi-asserted-by":"publisher","first-page":"146","DOI":"10.1210\/endo-105-1-146","volume":"105","author":"H-R Berthoud","year":"1979","unstructured":"Berthoud H-R, Jeanrenaud B (1979) Acute hyperinsulinemia and its reversal by vagotomy after lesions of the ventromedial hypothalamus in anesthetized rats. Endocrinology 105: 146\u2013151","journal-title":"Endocrinology"},{"key":"BF00254511_CR9","doi-asserted-by":"crossref","first-page":"719","DOI":"10.1152\/physrev.1979.59.3.719","volume":"59","author":"GA Bray","year":"1979","unstructured":"Bray GA, York DA (1979) Hypothalamic and genetic obesity in experimental animals: an autonomic and endocrine hypothesis. Physiol Rev 59: 719\u2013809","journal-title":"Physiol Rev"},{"key":"BF00254511_CR10","doi-asserted-by":"publisher","first-page":"203","DOI":"10.1016\/0165-1838(79)90017-1","volume":"1","author":"JD Coil","year":"1979","unstructured":"Coil JD, Norgren R (1979) Cells of origin of motor axons in the subdiaphragmatic vagus of the rat. J Autonomic Nerv Sys 1: 203\u2013210","journal-title":"J Autonomic Nerv Sys"},{"key":"BF00254511_CR11","doi-asserted-by":"publisher","first-page":"443","DOI":"10.2337\/diab.16.7.443","volume":"16","author":"LA Frohman","year":"1967","unstructured":"Frohman LA, Ezdinli JR (1967) Effect of vagotomy and vagal stimulation on insulin release. Diabetes 16: 443\u2013448","journal-title":"Diabetes"},{"key":"BF00254511_CR12","doi-asserted-by":"publisher","first-page":"488","DOI":"10.1126\/science.182.4111.488","volume":"182","author":"RM Gold","year":"1973","unstructured":"Gold RM (1973) Hypothalamic obesity: the myth of the ventromedial nucleus. Science 182: 488\u2013490","journal-title":"Science"},{"key":"BF00254511_CR13","doi-asserted-by":"publisher","first-page":"1111","DOI":"10.1016\/0031-9384(77)90019-1","volume":"18","author":"RM Gold","year":"1977","unstructured":"Gold RM, Jones AP, Sawchenko PE, Kapatos G (1977) Paraventricular area: Critical focus of a longitudinal neurocircuitry mediating food intake. Physiol Behav 18: 1111\u20131119","journal-title":"Physiol Behav"},{"key":"BF00254511_CR14","doi-asserted-by":"crossref","first-page":"769","DOI":"10.1152\/ajplegacy.1970.218.3.769","volume":"218","author":"PW Han","year":"1970","unstructured":"Han PW, Yu Y-K, Chow SL (1970) Enlarged pancreatic islets of tube-fed hypophysectomized rats bearing hypothalamic lesions. Am J Physiol 218: 769\u2013771","journal-title":"Am J Physiol"},{"key":"BF00254511_CR15","doi-asserted-by":"publisher","first-page":"726","DOI":"10.2337\/diab.26.8.726","volume":"26","author":"DE Hill","year":"1977","unstructured":"Hill DE, Mayes S, Di Battista D, Lockhart-Ewart R, Martin JM (1977) Hypothalamic regulation of insulin release in rhesus monkeys. Diabetes 26: 726\u2013731","journal-title":"Diabetes"},{"key":"BF00254511_CR16","doi-asserted-by":"publisher","first-page":"601","DOI":"10.1677\/joe.0.0510601","volume":"51","author":"LA Idahl","year":"1971","unstructured":"Idahl LA, Martin JM (1971) Stimulation of insulin release by a ventrolateral hypothalamic factor. J Endocrinol 51: 601\u2013602","journal-title":"J Endocrinol"},{"key":"BF00254511_CR17","doi-asserted-by":"publisher","first-page":"108","DOI":"10.1210\/endo-100-1-108","volume":"100","author":"S Inoue","year":"1977","unstructured":"Inoue S, Bray GA (1977) The effects of subdiaphragmatic vagotomy in rats with ventromedial hypothalamic obesity. Endocrinology 100: 108\u2013114","journal-title":"Endocrinology"},{"key":"BF00254511_CR18","first-page":"E266","volume":"235","author":"S Inoue","year":"1978","unstructured":"Inoue S, Bray GA, Mullen YS (1978) Transplantation of pancreatic \u03b2-cells prevents development of hypothalamic obesity in rats. Am J Physiol 235: E266-E271","journal-title":"Am J Physiol"},{"key":"BF00254511_CR19","doi-asserted-by":"publisher","first-page":"2102","DOI":"10.1172\/JCI107395","volume":"52","author":"J Iversen","year":"1973","unstructured":"Iversen J (1973) Adrenergic receptors and the secretion of insulin and glucagon from the isolated, perfused canine pancreas. J Clin Invest 52: 2102\u20132116","journal-title":"J Clin Invest"},{"key":"BF00254511_CR20","doi-asserted-by":"publisher","first-page":"381","DOI":"10.2337\/diab.22.5.381","volume":"22","author":"J Iversen","year":"1973","unstructured":"Iversen J (1973) Effect of acetylocholine on the secretion of glucagon and insulin from the isolated, perfused canine pancreas. Diabetes 22: 381\u2013387","journal-title":"Diabetes"},{"key":"BF00254511_CR21","doi-asserted-by":"publisher","first-page":"188","DOI":"10.1111\/j.1748-1716.1978.tb06266.x","volume":"104","author":"J J\u00e4rhult","year":"1978","unstructured":"J\u00e4rhult J, Holst JJ (1978) Reflex adrenergic control of endocrine pancreas evoked by unloading of carotid baroreceptors in cats. Acta Physiol Scand 104: 188\u2013202","journal-title":"Acta Physiol Scand"},{"key":"BF00254511_CR22","doi-asserted-by":"publisher","first-page":"530","DOI":"10.1210\/endo-80-3-530","volume":"80","author":"A Kaneto","year":"1967","unstructured":"Kaneto A, Kosaka K, Nakao K (1967) Effects of stimulation of the vagus nerve on insulin secretion. Endocrinology 80: 530\u2013536","journal-title":"Endocrinology"},{"key":"BF00254511_CR23","first-page":"46","volume":"5","author":"W Laughton","year":"1979","unstructured":"Laughton W, Powley TL (1979) Four central nervous system sites project to the pancreas. Soc Neurosci Abstr 5: 46","journal-title":"Soc Neurosci Abstr"},{"key":"BF00254511_CR24","doi-asserted-by":"publisher","first-page":"421","DOI":"10.1002\/cne.901810211","volume":"181","author":"AD Loewy","year":"1978","unstructured":"Loewy AD, Burton H (1978) Nuclei of the solitary tract: efferent projections to the lower brain stem and spinal cord of the cat. J Comp Neurol 181: 421\u2013449","journal-title":"J Comp Neurol"},{"key":"BF00254511_CR25","doi-asserted-by":"publisher","first-page":"390","DOI":"10.1016\/0006-8993(75)90753-2","volume":"96","author":"JF Lorden","year":"1975","unstructured":"Lorden JF, Oltmans GA, Margules DL (1975) Central catecholamine levels in genetically obese mice (ob\/ob and db\/ db). Brain Res 96: 390\u2013394","journal-title":"Brain Res"},{"key":"BF00254511_CR26","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1152\/ajplegacy.1976.230.1.56","volume":"230","author":"J Louis-Sylvestre","year":"1976","unstructured":"Louis-Sylvestre J (1976) Preabsorptive insulin release and hypoglycemia in rats. Am J Physiol 230: 56\u201360","journal-title":"Am J Physiol"},{"key":"BF00254511_CR27","doi-asserted-by":"crossref","first-page":"1090","DOI":"10.1152\/ajplegacy.1976.230.4.1090","volume":"230","author":"RE Miller","year":"1976","unstructured":"Miller RE, Waid TH, Joyce MP (1976) Direct neural inhibition of insulin secretion in response to systemic hypoglycemia. Am J Physiol 230: 1090\u20131094","journal-title":"Am J Physiol"},{"key":"BF00254511_CR28","doi-asserted-by":"publisher","first-page":"89","DOI":"10.1037\/0033-295X.84.1.89","volume":"84","author":"TL Powley","year":"1977","unstructured":"Powley TL (1977) The ventromedial hypothalamic syndrome, satiety, and a cephalic phase hypothesis. Psychol Rev 84: 89\u2013126","journal-title":"Psychol Rev"},{"key":"BF00254511_CR29","doi-asserted-by":"publisher","first-page":"902","DOI":"10.1172\/JCI109744","volume":"65","author":"F Rohner-Jeanrenaud","year":"1980","unstructured":"Rohner-Jeanrenaud F, Jeanrenaud B (1980) Consequences of ventromedial hypothalamic lesions upon insulin and glucagon secretion by subsequently isolated perfused pancreases in the rat. J Clin Invest 65: 902\u2013910","journal-title":"J Clin Invest"},{"key":"BF00254511_CR30","first-page":"333","volume-title":"Integrative functions of the autonomic nervous system","author":"CB Saper","year":"1979","unstructured":"Saper CB (1979) Anatomical substrates for the hypothalamic control of the autonomic nervous system. In: McBrooks C, Koizumi K, Sato A (eds) Integrative functions of the autonomic nervous system. Univ of Tokyo Press, Tokyo, p 333\u2013341"},{"key":"BF00254511_CR31","doi-asserted-by":"publisher","first-page":"346","DOI":"10.1016\/0006-8993(77)91000-9","volume":"128","author":"LW Swanson","year":"1977","unstructured":"Swanson LW (1977) Immunohistochemical evidence for a neurophysin-containing autonomic pathway arising in the paraventricular nucleus of the hypothalamus. Brain Res 128: 346\u2013353","journal-title":"Brain Res"},{"key":"BF00254511_CR32","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1111\/j.1365-201X.1971.tb10998.x","volume":"367","author":"U Ungerstedt","year":"1971","unstructured":"Ungerstedt U (1971) Stereotaxic mapping of the monoamine pathways in the rat brain. Acta Physiol Scand [Suppl] 367: 1\u201348","journal-title":"Acta Physiol Scand [Suppl]"},{"key":"BF00254511_CR33","doi-asserted-by":"crossref","first-page":"596","DOI":"10.1152\/physrev.1974.54.3.596","volume":"54","author":"SC Woods","year":"1974","unstructured":"Woods SC, Porte D Jr (1974) Neural control of the endocrine pancreas. Physiol Rev 54: 596\u2013619","journal-title":"Physiol Rev"}],"container-title":["Diabetologia"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF00254511.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/BF00254511\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF00254511","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF00254511.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,4,3]],"date-time":"2020-04-03T04:45:07Z","timestamp":1585889107000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/BF00254511"}},"subtitle":["Multiple modes of expression"],"short-title":[],"issued":{"date-parts":[[1981,3]]},"references-count":33,"journal-issue":{"issue":"S1","published-print":{"date-parts":[[1981,3]]}},"alternative-id":["BF00254511"],"URL":"https:\/\/doi.org\/10.1007\/bf00254511","relation":{},"ISSN":["0012-186X","1432-0428"],"issn-type":[{"value":"0012-186X","type":"print"},{"value":"1432-0428","type":"electronic"}],"subject":[],"published":{"date-parts":[[1981,3]]}}}