{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T17:06:06Z","timestamp":1760979966491},"reference-count":26,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[1982,1,1]],"date-time":"1982-01-01T00:00:00Z","timestamp":378691200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cancer Chemother. Pharmacol."],"published-print":{"date-parts":[[1982]]},"DOI":"10.1007\/bf00265387","type":"journal-article","created":{"date-parts":[[2004,11,20]],"date-time":"2004-11-20T17:16:39Z","timestamp":1100970999000},"page":"97-102","source":"Crossref","is-referenced-by-count":40,"title":["A phase I study of human lymphoblastoid interferon administered by continuous intravenous infusion"],"prefix":"10.1007","volume":"9","author":[{"given":"A. Z. S.","family":"Rohatiner","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F. R.","family":"Balkwill","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D. B.","family":"Griffin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. S.","family":"Malpas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T. A.","family":"Lister","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"CR1","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1007\/BF00205403","volume":"7","author":"FR Balkwill","year":"1979","unstructured":"Balkwill FR (1979) Interferons as cell-regulatory molecules. Cancer Immunol Immunother 7:7?14","journal-title":"Cancer Immunol Immunother"},{"key":"CR2","doi-asserted-by":"crossref","first-page":"500","DOI":"10.1002\/ijc.2910200405","volume":"20","author":"F Balkwill","year":"1977","unstructured":"Balkwill F, Oliver RTD (1977) Growth inhibitory effect of interferon on normal and malignant human haemopoeitic cells. Int J Cancer 20:500?505","journal-title":"Int J Cancer"},{"key":"CR3","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1099\/00222615-3-2-251","volume":"3","author":"JG Christofinis","year":"1971","unstructured":"Christofinis JG (1971) Biological characteristics of a cell line GL-V3 derived from the kidney of a vervet monkey:Ceropithecus aethiops. J Med Microbiol 3:251?258","journal-title":"J Med Microbiol"},{"key":"CR4","first-page":"1045","volume":"54","author":"G Emodi","year":"1975","unstructured":"Emodi G, Just M, Hernandez R, Hirt HR (1975) Circulating interferon in man after administration of exogenous human leukocyte interferon. J Natl Cancer Inst 54:1045?1049","journal-title":"J Natl Cancer Inst"},{"key":"CR5","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1056\/NEJM197609022951001","volume":"295","author":"HB Greenberg","year":"1976","unstructured":"Greenberg HB, Pollard RB, Lutwick LI, Gregory PB, Robinson WS, Merigan TC (1976) Effect of human leukocyte interferon on hepatitis B virus infection in patients with chronic active hepatitis. N Engl J Med 295:517?522","journal-title":"N Engl J Med"},{"key":"CR6","doi-asserted-by":"crossref","first-page":"1052","DOI":"10.1073\/pnas.66.4.1052","volume":"66","author":"I Gresser","year":"1970","unstructured":"Gresser I, Brouty-Boye D, Thomas M-I, Macieira-Coelho A (1970) Interferon and cell division. I. Inhibition of the multiplication of mouse leukaemia L 1210 cells in vitro by interferon-preparations. Proc Natl Acad Sci USA 66:1052","journal-title":"Proc Natl Acad Sci USA"},{"key":"CR7","first-page":"4172","volume":"38","author":"EF Grollman","year":"1978","unstructured":"Grollman EF, Lee G, Ramos S, Lazo PS, Kaback HR, Friedman RM, Kohn LD (1978) Relationships of the structure and function of the interferon receptor to hormone receptors and establishment of the antiviral state. Cancer Res 38:4172?4175","journal-title":"Cancer Res"},{"key":"CR8","doi-asserted-by":"crossref","first-page":"388","DOI":"10.7326\/0003-4819-93-3-399","volume":"93","author":"JU Gutterman","year":"1980","unstructured":"Gutterman JU, Blumenschein GR, Alexanian R, Yap H-Y, Buzdar AU, Cabanillas F, Hortobagyi GN, Hersh EM, Rasmussen SL, Harmon M, Kramer M, Pestka S (1980) Leukocyte interferon-induced tumor regression in human metastatic breast cancer, multiple myeloma and malignant lymphoma. Ann Intern Med 93:388?406","journal-title":"Ann Intern Med"},{"key":"CR9","first-page":"67","volume":"8","author":"NO Hill","year":"1978","unstructured":"Hill NO, Loeb E, Pardue A, Khan A, Dorn GL, Comparini S, Hill JM (1978) Leukocyte interferon production and its effectiveness in acute lymphatic leukaemia. J Clin Hematol Oncol 8:67?82","journal-title":"J Clin Hematol Oncol"},{"key":"CR10","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1002\/mpo.2950090102","volume":"9","author":"NO Hill","year":"1981","unstructured":"Hill NO, Pardue A, Khan A, Aleman D, Hill JM (1981) High-dose human leukocyte interferon trials in leukemia and cancer. Med Pediatr Oncol 9:1","journal-title":"Med Pediatr Oncol"},{"key":"CR11","doi-asserted-by":"crossref","unstructured":"Horning SJ, Levine JF, Miller RA, Merigan TC (1982) Clinical and immunologic effects of recombinant leukocyte A interferon in eight patients with advanced cancer. Lancet (in press)","DOI":"10.1001\/jama.247.12.1718"},{"key":"CR12","doi-asserted-by":"crossref","first-page":"560","DOI":"10.1093\/infdis\/140.4.560","volume":"140","author":"S Ingimarsson","year":"1979","unstructured":"Ingimarsson S, Cantell K, Strander H (1979) Side effects of long-term treatment with human leukocyte interferon. J Infect Dis 140:560?563","journal-title":"J Infect Dis"},{"key":"CR13","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1098\/rspb.1957.0048","volume":"147","author":"A Isaacs","year":"1975","unstructured":"Isaacs A, Lindenmann J (1975) Virus interference. I. The interferon. Proc R Soc Lond [B] 147:258?267","journal-title":"Proc R Soc Lond [B]"},{"key":"CR14","unstructured":"Karanes C, Wolfe SN, Herzig GP, Phillips GL, Lazarus HM, Herzig RH (1979) High-dose cytosine arabinoside (AraC) in the treatment of patients with acute non-lymphocytic leukaemia (ANLL). Blood Abstracts 504:191a"},{"key":"CR15","first-page":"1907","volume":"62","author":"AS Levine","year":"1978","unstructured":"Levine AS, Levy HB (1978) Phase I?II trials of poly IC stabilized with poly-l-lysine. Cancer Treat Rep 62:1907?1912","journal-title":"Cancer Treat Rep"},{"key":"CR16","doi-asserted-by":"crossref","first-page":"712","DOI":"10.1182\/blood.V58.4.712.712","volume":"58","author":"AC Louie","year":"1981","unstructured":"Louie AC, Gallagher JG, Sikora K, Levy R, Rosenberg SA, Merigan TC (1981) Follow-up observations on the effect of human leukocyte interferon in non-Hodgkin's lymphoma. Blood 58:712?718","journal-title":"Blood"},{"key":"CR17","doi-asserted-by":"crossref","first-page":"628","DOI":"10.1111\/j.1749-6632.1980.tb20690.x","volume":"350","author":"E Lundgren","year":"1980","unstructured":"Lundgren E, Hill\u00f6rn W, Holmberg D, Lenner P, Roos G (1980) Comparative study on the effects of fibroblast and leukocyte interferon on short term cultures of leukemic cells. Ann NY Acad Sci 350:628","journal-title":"Ann NY Acad Sci"},{"key":"CR18","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1016\/S0140-6736(79)90770-0","volume":"I","author":"H Mellstedt","year":"1979","unstructured":"Mellstedt H, Bjorkholm M, Johansson B, Ahre A, Holm G, Strander H (1979) Interferon therapy in myelomatosis. Lancet I:245?247","journal-title":"Lancet"},{"key":"CR19","first-page":"541","volume":"35","author":"TC Merigan","year":"1977","unstructured":"Merigan TC (1977) Pharmacokinetics and side effects of interferon in man. Tex Rep Biol Med 35:541?547","journal-title":"Tex Rep Biol Med"},{"key":"CR20","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1016\/S0140-6736(80)90004-5","volume":"II","author":"TJ Priestman","year":"1980","unstructured":"Priestman TJ (1980) Initial evaluation of human lymphoblastoid interferon inpatients with advanced malignant disease. Lancet II:113?118","journal-title":"Lancet"},{"key":"CR21","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1007\/978-3-642-67984-1_9","volume-title":"Modern trends in human leukaemia, vol IV","author":"AZS Rohatiner","year":"1981","unstructured":"Rohatiner AZS, Balkwill F, Malpas JS, Lister TA (1981) A Phase I study of human lymphoblastoid interferon in patients with haematological malignancies. In: Modern trends in human leukaemia, vol IV. Springer, Berlin Heidelberg New York, pp 63?67"},{"key":"CR22","volume-title":"Interferons and their applications","author":"AM Salazar","year":"1982","unstructured":"Salazar AM, Gibbs CJ, Gajdusek DC, Smith RA (1982) Clinical usage of interferons in central nervous system disorders. In: Came P, Carter W (eds) Interferons and their applications. Springer, Berlin Heidelberg New York, (in press)"},{"key":"CR23","doi-asserted-by":"crossref","first-page":"1345","DOI":"10.1136\/bmj.282.6273.1345","volume":"282","author":"GM Scott","year":"1981","unstructured":"Scott GM, Secher DS, Flowers D, Bate J, Cantell K, Tyrell DAJ (1981) Toxicity of interferon. Br Med J 282:1345?1348","journal-title":"Br Med J"},{"key":"CR24","doi-asserted-by":"crossref","first-page":"733","DOI":"10.1093\/jnci\/51.3.733","volume":"5","author":"H Strander","year":"1973","unstructured":"Strander H, Cantell K, Carlstrom G, Jakobsson PA (1973) Clinical and laboratory investigations on man: systemic administration of potent interferon to man. J Natl Cancer Inst 5:733?742","journal-title":"J Natl Cancer Inst"},{"key":"CR25","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1182\/blood.V56.3.549.549","volume":"56","author":"R Taetle","year":"1980","unstructured":"Taetle R, Buick RN, McCulloch EA (1980) Effect of interferon on colony formation in culture by blast cell progenitors in acute myeloblastic leukaemia. Blood 56:549?552","journal-title":"Blood"},{"key":"CR26","unstructured":"Taylor-Papadimitriou J (1980) Effects of interferons on cell growth and function. In: Interferon II, 13?46"}],"container-title":["Cancer Chemotherapy and Pharmacology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF00265387.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/BF00265387\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF00265387","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,4,4]],"date-time":"2020-04-04T06:34:37Z","timestamp":1585982077000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/BF00265387"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1982]]},"references-count":26,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1982]]}},"alternative-id":["BF00265387"],"URL":"https:\/\/doi.org\/10.1007\/bf00265387","relation":{},"ISSN":["0344-5704","1432-0843"],"issn-type":[{"value":"0344-5704","type":"print"},{"value":"1432-0843","type":"electronic"}],"subject":[],"published":{"date-parts":[[1982]]}}}