{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T14:01:02Z","timestamp":1791900062424,"version":"4.3.4"},"reference-count":21,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[1987,10,1]],"date-time":"1987-10-01T00:00:00Z","timestamp":560044800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Hum Genet"],"published-print":{"date-parts":[[1987,10]]},"DOI":"10.1007\/bf00272390","type":"journal-article","created":{"date-parts":[[2004,10,5]],"date-time":"2004-10-05T13:14:44Z","timestamp":1096982084000},"page":"188-192","source":"Crossref","is-referenced-by-count":50,"title":["Follow-up 20 years later of 34 Klinefelter males with karyotype 47,XXY and 16 hypogonadal males with karyotype 46,XY"],"prefix":"10.1007","volume":"77","author":[{"given":"J.","family":"Nielsen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B.","family":"Pelsen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"CR1","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1111\/j.1600-0447.1970.tb02102.x","volume":"46","author":"A-L Annell","year":"1970","unstructured":"Annell A-L, Gustavson K-H, Tenstam J (1970) Symptomatology in schoolboys with positive sex chromatin (the Klinefelter syndrome). Acta Psychiatr Scand 46:71?80","journal-title":"Acta Psychiatr Scand"},{"key":"CR2","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1007\/978-3-642-69644-2_10","volume-title":"Klinefelter's syndrome","author":"R Breit","year":"1984","unstructured":"Breit R (1984) Lower leg ulcers in Klinefelter's syndrome. In: Bandmann H-J, Breit R (eds) Klinefelter's syndrome. Springer, Berlin Heidelberg New York, pp 71?79"},{"key":"CR3","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1016\/S0022-3476(72)80586-9","volume":"80","author":"PD Caldwell","year":"1972","unstructured":"Caldwell PD, Smith DW (1972) The XXY (Klinefelter's) syndrome in childhood: detection and treatment. J Pediatr 80:250?257","journal-title":"J Pediatr"},{"key":"CR4","first-page":"1","volume":"16","author":"A Fr\u00f8land","year":"1969","unstructured":"Fr\u00f8land A (1969) Klinefelter's syndrome. Dan Med Bull [Suppl] 16: pp 1?108","journal-title":"Dan Med Bull [Suppl]"},{"key":"CR5","first-page":"305","volume":"35","author":"M Fromantin","year":"1974","unstructured":"Fromantin M, Gautier D, Cuisinier JC, Belloir C (1974) Resultats de l'androg\u00e9noth\u00e9rapie dans le syndrome de Klinefelter de l'adolescent. Ann Endocrinol (Paris) 35:305?306","journal-title":"Ann Endocrinol (Paris)"},{"key":"CR6","series-title":"Birth Defects: Original Article Ser","volume-title":"Children with sex chromosome aneuploidy: follow-up studies","author":"M Higurashi","year":"1982","unstructured":"Higurashi M, Iijima K, Ikeda Y, Egi S, Ohzeki T (1982) An anthropometric study of cases with Turner syndrome and XYY. In: Stewart DA, Greene SC (eds) Children with sex chromosome aneuploidy: follow-up studies. Birth Defects: Original Article Ser 18, No. 4. The National Foundation, New York"},{"key":"CR7","first-page":"543","volume":"14","author":"CF Johnson","year":"1975","unstructured":"Johnson CF (1975) Management of Klinefelter's syndrome. Clin Pediatr (Phila) 14:543?549","journal-title":"Clin Pediatr (Phila)"},{"key":"CR8","series-title":"Birth Defects: Original Article Ser","volume-title":"Children with sex chromosome aneuploidy: follow-up studies","author":"MF Leonard","year":"1982","unstructured":"Leonard MF, Sparrow S, Schowalter JE (1982) Chromosome anomalies ? New Haven study III. The middle years. In: Stewart DA, Greene SC (eds) Children with sex chromosome aneuploidy: follow-up studies. Birth Defects: Original Article Ser 18, No 4. The National Foundation, New York"},{"key":"CR9","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1016\/S0140-6736(71)90779-3","volume":"I","author":"DJ Mantle","year":"1971","unstructured":"Mantle DJ, Pye C, Hardisty RM, Vessey MP (1971) Plasma factor-VIII concentrations in XXX women. Lancet I:58?61","journal-title":"Lancet"},{"key":"CR10","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1007\/BF00286848","volume":"33","author":"J Nielsen","year":"1976","unstructured":"Nielsen J, Sillesen I (1976) Follow-up till age 3?4 of unselected children with sex chromosome abnormalities. Hum Genet 33:241?257","journal-title":"Hum Genet"},{"key":"CR11","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1007\/978-3-642-69644-2_22","volume-title":"Klinefelter's syndrome","author":"J Nielsen","year":"1984","unstructured":"Nielsen J, S\u00f8rensen K (1984) The importance of early diagnosis of Klinefelter's syndrome. In: Bandmann H-J, Breit R (eds) Klinefelter's syndrome. Springer, Berlin Heidelberg New York, pp 170?187"},{"key":"CR12","volume-title":"A psychiatric-psychological study of 50 severely hypogonadal male patients, including 34 with Klinefelter's syndrome, 47,XXY","author":"J Neilsen","year":"1969","unstructured":"Neilsen J, S\u00f8rensen A, Theilgaard A, Fr\u00f8land A, Johnsen SG (1969) A psychiatric-psychological study of 50 severely hypogonadal male patients, including 34 with Klinefelter's syndrome, 47,XXY. Munksgaard, Copenhagen"},{"key":"CR13","series-title":"Birth Defects: Original Article Ser","volume-title":"Sex chromosome aneuploidy: prospective studies on children","author":"J Nielsen","year":"1979","unstructured":"Nielsen J, Sillesen I, S\u00f8rensen AM, S\u00f8rensen K (1979) Follow-up till age 4?8 of 25 unselected children with sex chromosome abnormalities, compared with siblings and controls. In: Robinson A, Lubs HA, Bergsma D (eds) Sex chromosome aneuploidy: prospective studies on children. Birth Defects: Original Article Ser 15, No 1. The National Foundation, New York"},{"key":"CR14","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1017\/S0033291700044111","volume":"10","author":"J Nielsen","year":"1980","unstructured":"Nielsen J, Johnsen SG, S\u00f8rensen K (1980) Follow-up 10 years later of 34 Klinefelter males with karyotype 47,XXY and 16 hypogonadal males with karyotype 46,XY. Psychol Med 10:345?352","journal-title":"Psychol Med"},{"key":"CR15","series-title":"Birth Defects: Original Article Ser","volume-title":"Children with sex chromosome aneuploidy: follow-up studies","author":"J Nielsen","year":"1982","unstructured":"Nielsen J, S\u00f8rensen AM, S\u00f8rensen K (1982) Follow-up until age 7 to 11 of 25 unselected children with sex chromosome abnormalities. In: Stewart DA, Greene SC (eds) Children with sex chromosome aneuploidy: follow-up studies. Birth Defects: Original Article Ser 18, No 4. The National Foundation, New York"},{"key":"CR16","series-title":"Birth Defects: Original Article Ser","volume-title":"Children with sex chromosome aneuploidy: follow-up studies","author":"SG Ratcliffe","year":"1982","unstructured":"Ratcliffe SG, Tierney I, Nshaho J, Smith L, Springbett A, Callan S (1982) The Edinburgh study of growth and development of children with sex chromosome abnormalities. In: Stewart DA, Greene SC (eds) Children with sex chromosome aneuploidy: follow-up studies. Birth Defects: Original Article Ser 18, No 4. The National Foundation, New York"},{"key":"CR17","series-title":"Birth Defects: Original Article Ser","volume-title":"Children with sex chromosome aneuploidy: follow-up studies","author":"A Robinson","year":"1982","unstructured":"Robinson A, Bender B, Borelli J, Puck M, Salbenblatt J, Webber ML (1982) Sex chromosomal abnormalities (SCA): a prospective and longitudinal study of newborns identified in an unbiased manner. In: Stewart DA, Greene SC (eds) Children with sex chromosome aneuploidy: follow-up studies. Birth Defects: Original Article Ser 18, No 4. The National Foundation, New York"},{"key":"CR18","first-page":"45","volume-title":"Human behavior and genetics","author":"K S\u00f8rensen","year":"1981","unstructured":"S\u00f8rensen K, S\u00f8rensen AM, Nielsen J (1981) Social and psychological development of adolescents with Klinefelter's syndrome. In: Schmid W, Nielsen J (eds) Human behavior and genetics. Elsevier\/North-Holland, Amsterdam New York, pp 45?64"},{"key":"CR19","series-title":"Birth Defects: Original Article Ser","volume-title":"Children with sex chromosome aneuploidy: follow-up studies","author":"DA Stewart","year":"1982","unstructured":"Stewart DA, Netley CT, Park E (1982) Summary of clinical findings of children with 47,XXY, 47,XYY and 47,XXX karyotypes. In: Stewart DA, Greene SC (eds) Children with sex chromosome aneuploidy: follow-up studies. Birth Defects: Original Article Ser 18, No 4. The National Foundation, New York"},{"key":"CR20","volume-title":"A psychological-psychiatric study of patients with Klinefelter's syndrome, 47,XXY","author":"A Theilgaard","year":"1971","unstructured":"Theilgaard A, Nielsen J, S\u00f8rensen A, Fr\u00f8land A, Johnsen SG (1971) A psychological-psychiatric study of patients with Klinefelter's syndrome, 47,XXY. Munksgaard, Copenhagen"},{"key":"CR21","series-title":"Birth Defects: Original Article Ser","volume-title":"Children with sex chromosome aneuploidy: follow-up studies","author":"S Walzer","year":"1982","unstructured":"Walzer S, Graham JM, Bashir AS, Silbert AR (1982) Preliminary observations on language and learning in XXY boys. In: Stewart DA, Greene SC (eds) Children with sex chromosome aneuploidy: follow-up studies. Birth Defects: Original Article Ser 18, No 4. The National Foundation, New York"}],"container-title":["Human Genetics"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF00272390.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/BF00272390\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF00272390","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,4,3]],"date-time":"2019-04-03T19:22:33Z","timestamp":1554319353000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/BF00272390"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1987,10]]},"references-count":21,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1987,10]]}},"alternative-id":["BF00272390"],"URL":"https:\/\/doi.org\/10.1007\/bf00272390","relation":{},"ISSN":["0340-6717","1432-1203"],"issn-type":[{"value":"0340-6717","type":"print"},{"value":"1432-1203","type":"electronic"}],"subject":[],"published":{"date-parts":[[1987,10]]}}}