{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,6,27]],"date-time":"2025-06-27T22:22:00Z","timestamp":1751062920136},"reference-count":19,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[1988,6,1]],"date-time":"1988-06-01T00:00:00Z","timestamp":581126400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Hum Genet"],"published-print":{"date-parts":[[1988,6]]},"DOI":"10.1007\/bf00280555","type":"journal-article","created":{"date-parts":[[2004,10,3]],"date-time":"2004-10-03T21:36:54Z","timestamp":1096839414000},"page":"151-156","source":"Crossref","is-referenced-by-count":13,"title":["Chromosome abnormalities in tuberous sclerosis"],"prefix":"10.1007","volume":"79","author":[{"given":"Susi","family":"Scappaticci","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.","family":"Cerimele","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Tondi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rossella","family":"Vivarelli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Fois","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Fraccaro","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"CR1","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1016\/0165-4608(86)90093-2","volume":"20","author":"R Bamezai","year":"1986","unstructured":"Bamezai R, Shiraishi Y, Taguchi H (1986) Centromere spreading in a case of megaloblastic anemia ?cured? under Tc 199 culture condition. Cancer Genet Cytogenet 20:341?343","journal-title":"Cancer Genet Cytogenet"},{"key":"CR2","doi-asserted-by":"crossref","first-page":"1275","DOI":"10.1016\/S0140-6736(86)92697-8","volume":"I","author":"JM Connor","year":"1986","unstructured":"Connor JM, Stephenson JBP, Hadley MDM (1986) Non-penetrance in tuberous sclerosis. Lancet I:1275","journal-title":"Lancet"},{"key":"CR3","doi-asserted-by":"crossref","first-page":"544","DOI":"10.1136\/jmg.24.9.544","volume":"24","author":"JM Connor","year":"1987","unstructured":"Connor JM, Pirrit LA, Yates JRW, Fryer AE, Ferguson-Smith MA (1987) Linkage of the tuberous sclerosis locus to a DNA polymorphism detected by v-abl. J Med Genet 24:544?546","journal-title":"J Med Genet"},{"key":"CR4","first-page":"569","volume":"II","author":"CL Dietrich","year":"1986","unstructured":"Dietrich CL, Krone W, Hesse G (1986) Chromosomal anomalies in cell cultures derived from angiofibromas of patients with tuberous sclerosis. 7th International Congress of Human Genetics, Berlin, 1986, vol II, pp 569?570 (abstr)","journal-title":"7th International Congress of Human Genetics, Berlin, 1986"},{"key":"CR5","first-page":"569","volume":"I","author":"AE Fryer","year":"1987","unstructured":"Fryer AE, Connor JM, Povey S, Yates JRW, Chalmers A, Fraser I, Yates AD, Osborne JP (1987) Evidence that the gene for tuberous sclerosis is on chromosome 9. Lancet I:569?660","journal-title":"Lancet"},{"key":"CR6","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1159\/000132299","volume":"43","author":"J Gabarron","year":"1986","unstructured":"Gabarron J, Jimenez A, Glover G (1986) Premature centromere division dominantly inherited in a subfertile family. Cytogenet Cell Genet 43:69?71","journal-title":"Cytogenet Cell Genet"},{"key":"CR7","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/0165-4608(84)90121-3","volume":"12","author":"JH Gallo","year":"1984","unstructured":"Gallo JH, Masawa S, Testa R (1984) Centromere spreading in acute nonlymphocytic leukemia. Cancer Genet Cytogenet 12:105?109","journal-title":"Cancer Genet Cytogenet"},{"key":"CR8","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1111\/j.1399-0004.1979.tb01354.x","volume":"16","author":"J German","year":"1979","unstructured":"German J (1979) Roberts' syndrome. I. Cytological evidence for a disturbance in chromatid pairing. Clin Genet 16:441?447","journal-title":"Clin Genet"},{"key":"CR9","doi-asserted-by":"crossref","first-page":"800","DOI":"10.1182\/blood.V27.6.800.800","volume":"27","author":"CW Heath","year":"1966","unstructured":"Heath CW (1966) Cytogenetic observation in vitamin B12 and folate deficiency. Blood 27:800?815","journal-title":"Blood"},{"key":"CR10","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1136\/jmg.21.4.272","volume":"21","author":"A Hunt","year":"1984","unstructured":"Hunt A, Lindenbaum RH (1984) Tuberous sclerosis: a new estimate of prevalence within the Oxford region. J Med Genet 21:272?277","journal-title":"J Med Genet"},{"key":"CR11","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1111\/j.1346-8138.1984.tb01472.x","volume":"11","author":"Y Ishibashi","year":"1984","unstructured":"Ishibashi Y, Inoue Y, Takehara K, Furue M, Kukita A (1984a) Disturbed mitotic processes of stroma cells in a patient with tuberous sclerosis. J Dermatol (Tokyo) 11:236?252","journal-title":"J Dermatol (Tokyo)"},{"key":"CR12","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1111\/j.1346-8138.1984.tb01455.x","volume":"11","author":"Y Ishibashi","year":"1984","unstructured":"Ishibashi Y, Indue Y, Takehara K, Kukita A, Murakami Y, Hanoaka F, Yamada M (1984b) Abnormal and unstable patterns of the DNA of stroma cells in a patient with tuberous sclerosis. J Dermatol (Tokyo) 11:139?147","journal-title":"J Dermatol (Tokyo)"},{"key":"CR13","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/0165-4608(85)90003-2","volume":"16","author":"LG Littlefield","year":"1985","unstructured":"Littlefield LG, Joiner EE, Sayer AM (1985) Premature separation of centromeres in marrow chromosomes from an untreated patient with acute myelogenous leukemia. Cancer Genet Cytogenet 16: 109?116","journal-title":"Cancer Genet Cytogenet"},{"key":"CR14","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1007\/BF00272391","volume":"77","author":"K Madan","year":"1987","unstructured":"Madan K, Lindhout D, Palan A (1987) Premature centromere division (PCD): a dominantly inherited cytogenetic anomaly. Hum Genet 77:193?196","journal-title":"Hum Genet"},{"key":"CR15","volume-title":"The biology of mental defect","author":"LS Penrose","year":"1963","unstructured":"Penrose LS (1963) The biology of mental defect, 3rd edn. Sidgwick and Jackson, London","edition":"3rd edn."},{"key":"CR16","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1007\/BF00286646","volume":"65","author":"NL Rudd","year":"1983","unstructured":"Rudd NL, Teshima I, Martin RH, Sisken JE, Weksberg R (1983) A dominantly inherited cytogenetic anomaly: a possible cell division mutant. Hum Genet 65:117?121","journal-title":"Hum Genet"},{"key":"CR17","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1111\/1523-1747.ep12506550","volume":"78","author":"DA Scudiero","year":"1981","unstructured":"Scudiero DA, Moshell A, Scarpinato R, Meyer S, Clatterbuck B, Tarone R, Robbins J (1981) Lymphoblastoid lines and skin fibroblasts from patients with tuberous sclerosis are abnormally sensitive to ionizing radiation and to a radiomimetic chemical. J Invest Dermatol 78:234?238","journal-title":"J Invest Dermatol"},{"key":"CR18","first-page":"247","volume":"57","author":"BK Vig","year":"1981","unstructured":"Vig BK (1981) Sequence of centromere separation: analysis of mitotic chromosomes in man. Hum Genet 57:247?252","journal-title":"Hum Genet"},{"key":"CR19","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1016\/0165-4608(86)90180-9","volume":"23","author":"S Zhang","year":"1986","unstructured":"Zhang S (1986) Centromere spreading and out-of-phase chromatid separation in Burkitt's lymphoma and nasopharyngeal carcinoma. Cancer Genet Cytogenet 23:211?217","journal-title":"Cancer Genet Cytogenet"}],"container-title":["Human Genetics"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF00280555.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/BF00280555\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF00280555","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,4,3]],"date-time":"2020-04-03T07:48:43Z","timestamp":1585900123000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/BF00280555"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1988,6]]},"references-count":19,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1988,6]]}},"alternative-id":["BF00280555"],"URL":"https:\/\/doi.org\/10.1007\/bf00280555","relation":{},"ISSN":["0340-6717","1432-1203"],"issn-type":[{"value":"0340-6717","type":"print"},{"value":"1432-1203","type":"electronic"}],"subject":[],"published":{"date-parts":[[1988,6]]}}}