{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,8]],"date-time":"2026-04-08T16:09:06Z","timestamp":1775664546267,"version":"3.50.1"},"reference-count":36,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[1992,2,1]],"date-time":"1992-02-01T00:00:00Z","timestamp":696902400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Urol. Res."],"published-print":{"date-parts":[[1992,2]]},"DOI":"10.1007\/bf00296521","type":"journal-article","created":{"date-parts":[[2004,10,6]],"date-time":"2004-10-06T10:23:23Z","timestamp":1097058203000},"page":"111-115","source":"Crossref","is-referenced-by-count":22,"title":["Renin-producing renal cell carcinomas?clinical and experimental investigations on a special form of renal hypertension"],"prefix":"10.1007","volume":"20","author":[{"given":"J.","family":"Steffens","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"Bock","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H. U.","family":"Braedel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.","family":"Isenberg","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C. P.","family":"B\ufffdhrle","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Ziegler","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"CR1","doi-asserted-by":"crossref","first-page":"554","DOI":"10.1136\/bmj.2.6035.554","volume":"2","author":"G Berglund","year":"1976","unstructured":"Berglund G, Andersson O, Wilhelmsen L (1976) Prevalence or primary and secondary hypertension: studies in a random population sample. Br Med J 2:554?559","journal-title":"Br Med J"},{"key":"CR2","first-page":"212","volume":"115","author":"M Cantin","year":"1984","unstructured":"Cantin M, Gutkowska J, Lacasse J, Ballak S, Ledoux S, Inagami T, Bcuzeron J, Genest J (1984) Ultrastructural immunocytochemical localization of renin and angiotensin II in the juxtaglo-merular cells of the ischemic kidney in experimental renal hypertension. Am J Pathol 115:212?224","journal-title":"Am J Pathol"},{"key":"CR3","doi-asserted-by":"crossref","first-page":"682","DOI":"10.1001\/archinte.1972.03650050016004","volume":"130","author":"JW Conn","year":"1972","unstructured":"Conn JW, Cohen EL, Lucas CP, McDonald WJ, Mayor GH, Blough WM, Eveland WC, Bookstein JJ, Lapides J (1972) Primary reninism. Hypertension, hyperreninemia and secondar hyperaldosteronism due to renin-producing juxtaglomerular cell tumors, Arch Intern Med 130:682?696","journal-title":"Arch Intern Med"},{"key":"CR4","doi-asserted-by":"crossref","first-page":"835","DOI":"10.7326\/0003-4819-79-6-835","volume":"79","author":"A Ganguly","year":"1973","unstructured":"Ganguly A, Gribble J, Tune B, Kemson RL, Luetscher JA (1973) Renin-secreting Wilms tumour with severe hypertension. Ann Intern Med 79:835?837","journal-title":"Ann Intern Med"},{"key":"CR5","first-page":"605","volume":"107","author":"P Greminger","year":"1977","unstructured":"Greminger P, Vetter W, Zimmermann K, Beckerhoff R, Siegenthaler W (1977) Prim\u00e4re und sekund\u00e4re Hypertonie in einem poliklinischen Patientengut. Schweiz Med Wochenschr 107:605","journal-title":"Schweiz Med Wochenschr"},{"key":"CR6","first-page":"62","volume-title":"Enzymatic release of vasoactive peptides","author":"E Hackenthal","year":"1980","unstructured":"Hackenthal E, Poulsen K, Taugner Ch, Taugner R (1980) Localization of renin in mouse kidney by the peroxidase-antiperoxidase technique. In: Gross F, Vogel G (eds) Enzymatic release of vasoactive peptides. Raven, New York, pp 62?72"},{"key":"CR7","doi-asserted-by":"crossref","first-page":"859","DOI":"10.1001\/archinte.1975.00330060103015","volume":"135","author":"JW Hillifield","year":"1977","unstructured":"Hillifield JW, Page DL, Smith C, Michelakis AM, Staab E, Rhamy R (1977) Renin-secreting clear cell carcinoma of the kidney. Arch Intern Med 135:859?864","journal-title":"Arch Intern Med"},{"key":"CR8","first-page":"351","volume-title":"Pathology annual","author":"T Kameya","year":"1980","unstructured":"Kameya T, Shimosata Y, Abe K, Takenchi T (1980) Morphologic and functional aspects of hormone-producing tumours. In: Sommers SC, Rosen PP (eds) Pathology annual. Appleton-Century Crofts, New York, pp 351?386"},{"key":"CR9","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1161\/01.RES.60.3.422","volume":"60","author":"J Kifor","year":"1987","unstructured":"Kifor J, Dzau VJ (1987) Endothelial renin-angiotensin pathway: evidence for intracellular synthesis and secretion of angiotensins. Circ Res 60:422?428","journal-title":"Circ Res"},{"key":"CR10","doi-asserted-by":"crossref","first-page":"1266","DOI":"10.1136\/bmj.285.6350.1266","volume":"285","author":"S Kumar","year":"1982","unstructured":"Kumar S, Winearls CG, Owen DL (1982) Facial palsy with severe hypertension due to renal tumor. Br Med J 285:1266?1269","journal-title":"Br Med J"},{"key":"CR11","doi-asserted-by":"crossref","first-page":"923","DOI":"10.1016\/S0022-5347(17)58250-6","volume":"118","author":"M Lebel","year":"1977","unstructured":"Lebel M, Talbot J, Grose J, Morin J (1977) Adenocarcinoma of the kidney and hypertension: report of two cases with special emphasis on renin. J Urol 118:923?927","journal-title":"J Urol"},{"key":"CR12","first-page":"159","volume":"55","author":"B Leckie","year":"1978","unstructured":"Leckie B, Brown JJ, Fraser R, Kyle K, Lever AF, Morton JJ, Robertson JIS (1978) A renal carcinoma secreting inactive renin. Clin Sci Mol Med 55:159?161","journal-title":"Clin Sci Mol Med"},{"key":"CR13","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1161\/01.RES.57.2.312","volume":"57","author":"LS Lilly","year":"1985","unstructured":"Lilly LS, Pratt RE, Alexander RW, Larson DM, Ellison KE, Gimbrone MA Jr, Dzau VJ (1985) Renin expression by vascular endothelial cells in culture. Circ Res 57:312?318","journal-title":"Circ Res"},{"key":"CR14","doi-asserted-by":"crossref","first-page":"498","DOI":"10.1007\/BF01740293","volume":"24\/25","author":"F Linder","year":"1947","unstructured":"Linder F (1947) \u00dcber blutdrucksteigernde Nierentumoren. Klin Wochenschr 24\/25:498?502","journal-title":"Klin Wochenschr"},{"key":"CR15","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1136\/jcp.37.1.27","volume":"37","author":"GBM Lindop","year":"1984","unstructured":"Lindop GBM, Fleming S (1984) Renin in renal cell carcinomaan immunocytochemical study using an antibody to pure human renin. J Clin Pathol 37:27?31","journal-title":"J Clin Pathol"},{"key":"CR16","doi-asserted-by":"crossref","first-page":"639","DOI":"10.1136\/jcp.36.6.639","volume":"36","author":"GBM Lindop","year":"1983","unstructured":"Lindop GBM, More IAR, Leckie B (1983) An ultrastructural and immunocytochemical study of a renal carcinoma secreting inactive renin. J Clin Pathol 36:639?645","journal-title":"J Clin Pathol"},{"key":"CR17","doi-asserted-by":"crossref","first-page":"738","DOI":"10.1136\/jcp.37.7.738","volume":"37","author":"GBM Lindop","year":"1984","unstructured":"Lindop GBM, Fleming S, Gibson AAM (1984) Immunocytochemical localization of renin in nephroblastoma. J Clin Pathol 37:738?742","journal-title":"J Clin Pathol"},{"key":"CR18","first-page":"123","volume":"20","author":"GJ Mast","year":"1981","unstructured":"Mast GJ, Isenberg E, Ziegler M, (1981) Renale Hypertonie als Folge urologischer Erkrankungen. Urologe [A] 20:123?129","journal-title":"Urologe [A]"},{"key":"CR19","first-page":"1034","volume-title":"Hypertension","author":"J Menard","year":"1983","unstructured":"Menard J, Soubrier F, Bariety J, Camilleri JP, Corvol P (1983) Hypertension. Primary reninism. In: Genest J (ed) Hypertension. McGraw Hill, New York, pp 1034?1040"},{"key":"CR20","first-page":"705","volume":"43","author":"AH Moss","year":"1982","unstructured":"Moss AH, Peterson LJ, Scott CW, Winter K, Olin DB, Garber RL (1982) Delayed diagnosis of juxtaglomerular cell tumour with hypertension. N C Med J 43:705?707","journal-title":"N C Med J"},{"key":"CR21","doi-asserted-by":"crossref","first-page":"907","DOI":"10.1016\/S0022-5347(17)52453-2","volume":"129","author":"AC Novick","year":"1983","unstructured":"Novick AC, Pohl MA, Schreiber M, Grifford RW Jr, Vidt DG (1983) Revascularization for preservation of renal function in patients with atherosclerotic renovascular disease. J Urol 129:907?912","journal-title":"J Urol"},{"key":"CR22","doi-asserted-by":"crossref","first-page":"963","DOI":"10.1016\/0002-9343(67)90256-2","volume":"43","author":"PW Robertson","year":"1967","unstructured":"Robertson PW, Klidjian A, Harding LK, Walters G, Lee MR, Robb-Smith AHT (1967) Hypertension due to a renin-secreting renal tumour. Am J Med 43:963?976","journal-title":"Am J Med"},{"key":"CR23","doi-asserted-by":"crossref","first-page":"820","DOI":"10.1001\/archinte.1987.00370050016004","volume":"147","author":"EJ Rocella","year":"1987","unstructured":"Rocella EJ and Working Group on Renovascular Hypertension (1987) Detection, evaluation and treatment of renovascular hypertension. Arch Intern Med 147:820?829","journal-title":"Arch Intern Med"},{"key":"CR24","doi-asserted-by":"crossref","first-page":"921","DOI":"10.1016\/S0022-3476(78)80361-8","volume":"92","author":"KJ Sheth","year":"1978","unstructured":"Sheth KJ, Tang JJ, Blaedel ME, Good TA (1978) Polydipsia, polyuria and hypertension associated with renin-secreting Wilm's tumour. J Pediatr 92:921?924","journal-title":"J Pediatr"},{"key":"CR25","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1016\/S0022-3468(81)80111-X","volume":"16","author":"J Spahr","year":"1981","unstructured":"Spahr J, Demers LM, Shochat SJ (1981) Renin producing Wilm's tumour. J Pediatr Surg 16:32?34","journal-title":"J Pediatr Surg"},{"key":"CR26","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1159\/000463868","volume":"18","author":"J Steffens","year":"1990","unstructured":"Steffens J, Bock R, Braedel HU, Isenberg E, B\u00fchrle CP, Ziegler M (1990) Renin producing renal cell carcinoma. Eur Urol 18:56","journal-title":"Eur Urol"},{"key":"CR27","doi-asserted-by":"crossref","first-page":"826","DOI":"10.1016\/S0022-5347(17)37932-6","volume":"146","author":"J Steffens","year":"1991","unstructured":"Steffens J, et al. (1991) Segmental renal hypoplasia of vascular origin causing renal hypertension in a 3-year-old girl. J Urol 146:826","journal-title":"J Urol"},{"key":"CR28","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1177\/18.5.315","volume":"18","author":"LA Sternberger","year":"1970","unstructured":"Sternberger LA, Hardy PH Jr, Cuculis JJ, Meyer HG (1970) The unlabeled antibody enzyme method of immunohistochemistry. Preparation and properties of soluble antigen-antibody-complex (horseradish peroxidase-anti-horseradish-peroxidase) and its use in the identification of spirochetes. J Histochem Cytochem 18:315?333","journal-title":"J Histochem Cytochem"},{"key":"CR29","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1007\/BF00537003","volume":"62","author":"C Taugner","year":"1979","unstructured":"Taugner C, Poulsen K, Hackenthal E, Taugner R (1979) Immunohistochemical localization of renin in mouse kidney. Histochemistry 62:19?27","journal-title":"Histochemistry"},{"key":"CR30","first-page":"1163","volume":"5","author":"R Taugner","year":"1983","unstructured":"Taugner R, B\u00fchrle CP, Ganten D Hackenthal E, Hardegg C, Hardegg G, Nobiling R (1983) Immunohistochemistry of the tenin-angiotensin-system in the kidney. Clin Exp Hypertens [A] 5:1163?1177","journal-title":"Clin Exp Hypertens [A]"},{"key":"CR31","first-page":"55","volume":"4","author":"B Tetu","year":"1984","unstructured":"Tetu B, Totovic V, Bechtelsheimer H, Smend J (1984) Tumeur r\u00e9nale \u00e0 s\u00e9cr\u00e9tion de r\u00e9nine. Ann Pathol 4:55?59","journal-title":"Ann Pathol"},{"key":"CR32","first-page":"73","volume":"126","author":"T Tomita","year":"1987","unstructured":"Tomita T, Poisner A, Inagami T (1987) Immunohistochemical localization of renin in tumors. Am J Pathol 126:73?80","journal-title":"Am J Pathol"},{"key":"CR33","doi-asserted-by":"crossref","first-page":"911","DOI":"10.1016\/S0022-5347(17)41890-8","volume":"140","author":"KL Wise","year":"1988","unstructured":"Wise KL, McCann RL, Dunnick NR, Paulson DF (1988) Renovascular hypertension. J Urol 140:911?924","journal-title":"J Urol"},{"key":"CR34","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1016\/S0022-3468(88)80435-4","volume":"23","author":"K Yokomori","year":"1988","unstructured":"Yokomori K, Hori T, Takemura T, Tsuchida Y (1988) Demonstration of both primary and secondary reninism in renal tumors in children. J Pediatr Surg 23:403?409","journal-title":"J Pediatr Surg"},{"key":"CR35","volume-title":"Hypertension","author":"M Ziegler","year":"1986","unstructured":"Ziegler M, Mast GJ (1986) Experimentelle Grundlagen und Klinik der renalen Hypertonie unter urologischen Aspekten. In: Rosenthal J (ed) Hypertension, Springer, Berlin Heidelberg New York p 331"},{"key":"CR36","unstructured":"Ziegler M, Althoff J, Mitsche L, M\u00f6hring H, M\u00f6hring K, Krempien B (1971) Renin in renal carcinoma tissue (abstract). European Society for Clinical Investigation Fifth Annual Meeting, Scheveningen, p 96"}],"container-title":["Urological Research"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF00296521.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/BF00296521\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF00296521","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,4,8]],"date-time":"2019-04-08T20:12:40Z","timestamp":1554754360000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/BF00296521"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1992,2]]},"references-count":36,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1992,2]]}},"alternative-id":["BF00296521"],"URL":"https:\/\/doi.org\/10.1007\/bf00296521","relation":{},"ISSN":["0300-5623","1434-0879"],"issn-type":[{"value":"0300-5623","type":"print"},{"value":"1434-0879","type":"electronic"}],"subject":[],"published":{"date-parts":[[1992,2]]}}}