{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,14]],"date-time":"2026-07-14T12:09:36Z","timestamp":1784030976672,"version":"3.55.0"},"reference-count":54,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[1992,8,1]],"date-time":"1992-08-01T00:00:00Z","timestamp":712627200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Calcif Tissue Int"],"published-print":{"date-parts":[[1992,8]]},"DOI":"10.1007\/bf00298497","type":"journal-article","created":{"date-parts":[[2004,10,26]],"date-time":"2004-10-26T13:58:36Z","timestamp":1098799116000},"page":"105-110","source":"Crossref","is-referenced-by-count":272,"title":["Annual injection of vitamin D and fractures of aged bones"],"prefix":"10.1007","volume":"51","author":[{"given":"Rauno Juhani","family":"Heikinheimo","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jukka Antero","family":"Inkovaara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Esko Juhani","family":"Harju","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matti Verner","family":"Haavisto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Riitta Helena","family":"Kaarela","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jorma Matti","family":"Kataja","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aino Marja-Liisa","family":"Kokko","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leena Anneli","family":"Kolho","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sulo Antero","family":"Rajala","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"CR1","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1079\/NRR19900008","volume":"3","author":"C Shortt","year":"1990","unstructured":"Shortt C, Flynn A (1990) Sodium-calcium interrelationships with specific reference to osteoporosis. Nutr Res Rev 3:101?115","journal-title":"Nutr Res Rev"},{"key":"CR2","first-page":"2321","volume":"82","author":"C Zetterberg","year":"1985","unstructured":"Zetterberg C (1985) Fordubbling av h\u00f6ftfrakturer att v\u00e4nta. Icke-\u00bbldersrelaterade \u00f6kningen forts\u00e4tter. L\u00e4kartidningen 82: 2321","journal-title":"L\u00e4kartidningen"},{"key":"CR3","first-page":"1562","volume":"83","author":"S Ljunghall","year":"1986","unstructured":"Ljunghall S, Hansson T, Johnell O, Mellstr\u00f6m D, Persson I (1986) Bensk\u00f6rhet hos \u00e4ldre. L\u00e4kartidningen 83:1562?1563","journal-title":"L\u00e4kartidningen"},{"key":"CR4","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1136\/bmj.1.6163.589","volume":"1","author":"MR Baker","year":"1979","unstructured":"Baker MR, McDonnell H, Peacock M, Nordin BEC (1979) Plasma 25-hydroxy vitamin D concentrations in patients with fractures of the femoral neck. Br Med J 1:589","journal-title":"Br Med J"},{"key":"CR5","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1093\/ageing\/15.1.35","volume":"15","author":"IR Reid","year":"1986","unstructured":"Reid IR, Gallagher DJA, Bosworth J (1986) Prophylaxis against vitamin D deficiency in the elderly by regular sunlight exposure. Age Ageing 15:35?40","journal-title":"Age Ageing"},{"key":"CR6","doi-asserted-by":"crossref","first-page":"514","DOI":"10.1136\/bmj.295.6597.514","volume":"295","author":"C Bulstrode","year":"1987","unstructured":"Bulstrode C (1987) Keeping up with orthopaedic epidemics. Br Med J 295:514","journal-title":"Br Med J"},{"key":"CR7","first-page":"63","volume":"1","author":"AR Gaby","year":"1990","unstructured":"Gaby AR, Wright JV (1990) Nutrients and osteoporosis. J Nutr Med 1:63?72","journal-title":"J Nutr Med"},{"key":"CR8","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1136\/bmj.3.5975.73","volume":"3","author":"J Inkovaara","year":"1975","unstructured":"Inkovaara J, Heikinheimo R, J\u00e4rvinen K, Kasurinen U, Hanhij\u00e4rvi H, Iisalo E (1975) Prophylactic fluoride treatment and aged bones. Br Med J 3:73?74","journal-title":"Br Med J"},{"key":"CR9","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1093\/ageing\/12.2.124","volume":"12","author":"J Inkovaara","year":"1983","unstructured":"Inkovaara J, Gothoni G, Halttula R, Heikinheimo R, Tokola O (1983) Calcium, vitamin D and anabolic steroid in treatment of aged bones: double-blind placebo-controlled long-term clinical trial. Age Ageing 12:124?130","journal-title":"Age Ageing"},{"key":"CR10","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1136\/bmj.294.6568.329","volume":"294","author":"R Smith","year":"1987","unstructured":"Smith R (1987) Osteoporosis: cause and management. Br Med J 294:329","journal-title":"Br Med J"},{"key":"CR11","doi-asserted-by":"crossref","first-page":"701","DOI":"10.1136\/bmj.294.6573.701-b","volume":"294","author":"AW Fowler","year":"1987","unstructured":"Fowler AW (1987) Osteoporosis: cause and management. Br Med J 294:701?702","journal-title":"Br Med J"},{"key":"CR12","doi-asserted-by":"crossref","first-page":"702","DOI":"10.1136\/bmj.294.6573.702-a","volume":"294","author":"RM Francis","year":"1987","unstructured":"Francis RM, Selby PL (1987) Osteoporosis: cause and management. Br Med J 294:702","journal-title":"Br Med J"},{"key":"CR13","doi-asserted-by":"crossref","first-page":"702","DOI":"10.1136\/bmj.294.6573.702-b","volume":"294","author":"ARP Walker","year":"1987","unstructured":"Walker ARP, Walker BF (1987) Osteoporosis: cause and management. Br Med J 294:702?703","journal-title":"Br Med J"},{"key":"CR14","doi-asserted-by":"crossref","first-page":"452","DOI":"10.1136\/bmj.301.6750.452","volume":"301","author":"R Smith","year":"1990","unstructured":"Smith R (1990) Osteoporosis after 60. Br Med J 301:452?453","journal-title":"Br Med J"},{"key":"CR15","doi-asserted-by":"crossref","first-page":"1047","DOI":"10.1136\/bmj.301.6759.1047-a","volume":"301","author":"M Davie","year":"1990","unstructured":"Davie M (1990) Osteoporosis after 60. Br Med J 301:1047","journal-title":"Br Med J"},{"key":"CR16","doi-asserted-by":"crossref","first-page":"1668","DOI":"10.1172\/JCI111373","volume":"73","author":"K-S Tsai","year":"1984","unstructured":"Tsai K-S, Heath H, Kumar R, Riggs BL (1984) Impaired vitamin D metabolism with aging in women. J Clin Invest 73:1668?1672","journal-title":"J Clin Invest"},{"key":"CR17","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1159\/000176796","volume":"28","author":"C Lamberg-Allardt","year":"1984","unstructured":"Lamberg-Allardt C (1984) Serum 25-hydroxy-vitamin D concentration and vitamin D intake. (Dissert Helsinki) Ann Nutr Metab 28:144?150","journal-title":"Ann Nutr Metab"},{"key":"CR18","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1016\/0009-8981(82)90078-X","volume":"120","author":"H Turnbull","year":"1982","unstructured":"Turnbull H, Trafford DJH, Makin HLJ (1982) A rapid and simple method for the measurement of plasma 25-hydroxyvitamin D2 and 25-hydroxyvitamin D3 using SepPak C18 cartridges and a single high performance liquid chromatographic step. Clin Chim Acta 120:65?76","journal-title":"Clin Chim Acta"},{"key":"CR19","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1016\/0009-8981(81)90396-X","volume":"114","author":"MT Parviainen","year":"1981","unstructured":"Parviainen MT, Savolainen KE, Korhonen PH, Alhava EM, Visakorpi JK (1981) An improved method for routine determination of vitamin D and its hydroxylated metabolites in serum from children and adults. Clin Chim Acta 114:233","journal-title":"Clin Chim Acta"},{"key":"CR20","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1210\/jcem-58-1-91","volume":"58","author":"TA Reinhardt","year":"1984","unstructured":"Reinhardt TA, Horst RL, Orf JW, Hollis BW (1984) A microassay for 1,25-dihydroxyvitamin D not requiring high performance liquid chromatography: application to clinical studies. J Clin Endocrinol Metab 58:91?98","journal-title":"J Clin Endocrinol Metab"},{"key":"CR21","unstructured":"World Health Organisation (1977) Manual of the International Statistical Classification of Diseases, Injuries and Causes of Health. Geneva"},{"key":"CR22","doi-asserted-by":"crossref","unstructured":"Heikinheimo RJ, Haavisto MV, Harju EJ, Inkovaara JA, Kaarela RH, Kolho LA, Rajala SA (1991) Serum vitamin D level after an annual intramuscular injection of ergocalciferol. Calcif Tissue Int (suppl)49:S87","DOI":"10.1007\/BF02555102"},{"key":"CR23","doi-asserted-by":"crossref","first-page":"1276","DOI":"10.1136\/bmj.295.6608.1276-a","volume":"295","author":"BEC Nordin","year":"1987","unstructured":"Nordin BEC, Need AG, Morris HA, Horowitz M (1987) Consensus on preventing osteoporosis. Br Med J 295:1276?1277","journal-title":"Br Med J"},{"key":"CR24","doi-asserted-by":"crossref","first-page":"906","DOI":"10.1210\/jcem-48-6-906","volume":"48","author":"MP Whyte","year":"1979","unstructured":"Whyte MP, Haddad JG, Walters DD, Stamp TCB (1979) Vitamin D bioavailability: serum 25-hydroxyvitamin D levels in man after oral, subcutaneous, intramuscular, and intravenous vitamin D administration. J Clin Endocrinol Metab 48:906?911","journal-title":"J Clin Endocrinol Metab"},{"key":"CR25","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1093\/ageing\/14.6.349","volume":"14","author":"M Davies","year":"1985","unstructured":"Davies M, Mawer EB, Hann JT, Stephens WP, Taylor JL (1985) Vitamin D prophylaxis in the elderly: a simple effective method suitable for large populations. Age Ageing 14:349?354","journal-title":"Age Ageing"},{"key":"CR26","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1136\/bmj.290.6464.281-a","volume":"290","author":"J Burns","year":"1985","unstructured":"Burns J, Paterson CR (1985) Single dose vitamin D treatment for osteomalacia in the elderly. Br Med J 290:281?282","journal-title":"Br Med J"},{"key":"CR27","first-page":"93","volume":"41","author":"Y Weisman","year":"1986","unstructured":"Weisman Y, Schen RJ, Eisenberg Z (1986) Vitamin D deficiency: one-dose prophylaxis for the elderly. Geriatrics 41:93","journal-title":"Geriatrics"},{"key":"CR28","unstructured":"(editorial) (1987) Vitamin D supplementation in the elderly. Lancet 1:306?307"},{"key":"CR29","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1111\/j.0954-6820.1982.tb01901.x","volume":"211","author":"GF Jensen","year":"1982","unstructured":"Jensen GF, Christiansen C, Transbol I (1982) 1,25(OH)2D3 and renal function. Acta Med Scand 211:51?54","journal-title":"Acta Med Scand"},{"key":"CR30","doi-asserted-by":"crossref","first-page":"267","DOI":"10.7326\/0003-4819-110-4-267","volume":"110","author":"SM Ott","year":"1989","unstructured":"Ott SM, Chesnut CH (1989) Calcitriol treatment is not effective in postmenopausal osteoporosis. Ann Int Med 110:267?274","journal-title":"Ann Int Med"},{"key":"CR31","first-page":"95","volume":"87","author":"GD Whedon","year":"1974","unstructured":"Whedon GD, Lutwak L, Reid J, Rambaut P, Whittle M, Smith M, Leach C (1974) Mineral and nitrogen metabolic studies on Skylab orbital space flights. Trans Assoc Am Physicians 87:95?110","journal-title":"Trans Assoc Am Physicians"},{"key":"CR32","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1016\/S0140-6736(74)92545-8","volume":"1","author":"JE Aaron","year":"1974","unstructured":"Aaron JE, Gallagher JC, Anderson J, Stasiak L, Longton EB, Nordin BEC, Nicholson M (1974) Frequency of osteomalacia and osteoporosis in fractures of the proximal femur. Lancet 1:229?233","journal-title":"Lancet"},{"key":"CR33","doi-asserted-by":"crossref","first-page":"1089","DOI":"10.1016\/S0140-6736(76)90060-X","volume":"i","author":"JM Faccini","year":"1976","unstructured":"Faccini JM, Exton-Smith AN, Boyde A (1976) Disorders of bone and fracture of the femoral neck. Lancet i:1089?1092","journal-title":"Lancet"},{"key":"CR34","doi-asserted-by":"crossref","first-page":"255","DOI":"10.3109\/17453678208992212","volume":"53","author":"V Hoikka","year":"1982","unstructured":"Hoikka V, Alhava EM, Savolainen K, Parviainen M (1982) Osteomalacia in fractures of the proximal femur. Acta Orthop Scand 53:255?260","journal-title":"Acta Orthop Scand"},{"key":"CR35","first-page":"45","volume":"16","author":"PJ Cook","year":"1982","unstructured":"Cook PJ, Exton-Smith AN, Brocklehurst JB, Lempert-Barber SM (1982) Fractured femurs, falls and bone disorders. JR Coll Physicians (London) 16:45?49","journal-title":"JR Coll Physicians (London)"},{"key":"CR36","doi-asserted-by":"crossref","first-page":"408","DOI":"10.1007\/BF00435450","volume":"103","author":"E Harju","year":"1985","unstructured":"Harju E, Sotaniemi E, Puranen J, Lahti R (1985) High incidence of low serum vitamin D concentration in patients with hip fracture. Arch Orthop Trauma Surg 103:408?416","journal-title":"Arch Orthop Trauma Surg"},{"key":"CR37","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1177\/030006058901700305","volume":"17","author":"E Harju","year":"1989","unstructured":"Harju E, Punnonen R, Tuimala R, Salmi J, Paronen I (1989) Vitamin D and calcitonin treatment in patients with femoral neck fracture: a prospective controlled clinical study. J Int Med Res 17:226?242","journal-title":"J Int Med Res"},{"key":"CR38","first-page":"67","volume":"42","author":"BEC Nordin","year":"1986","unstructured":"Nordin BEC (1986) Calcium. J Food Nutr 42:67?82","journal-title":"J Food Nutr"},{"key":"CR39","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1093\/ageing\/13.6.344","volume":"13","author":"TRO Beringer","year":"1984","unstructured":"Beringer TRO, MsSherry DMG, Taggart H McA (1984) A microcomputer-based audit of fracture of the proximal femur in the elderly. Age Ageing 13:344?348","journal-title":"Age Ageing"},{"key":"CR40","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1136\/bmj.288.6417.597","volume":"288","author":"JM Aitken","year":"1984","unstructured":"Aitken JM (1984) Relevance of osteoporosis in women with fracture of the femoral neck. Br Med J 288:597?601","journal-title":"Br Med J"},{"key":"CR41","doi-asserted-by":"crossref","first-page":"1084","DOI":"10.1136\/bmj.288.6423.1084-b","volume":"288","author":"JM Aitken","year":"1984","unstructured":"Aitken JM (1984) Relevance of osteoporosis in women with fracture of the femoral neck. Br Med J 288:1084?1085","journal-title":"Br Med J"},{"key":"CR42","doi-asserted-by":"crossref","first-page":"1083","DOI":"10.1136\/bmj.288.6423.1083-a","volume":"288","author":"J Grimley Evans","year":"1984","unstructured":"Grimley Evans J (1984) Relevance of osteoporosis in women with fracture of the femoral neck. Br Med J 288:1083","journal-title":"Br Med J"},{"key":"CR43","doi-asserted-by":"crossref","first-page":"1084","DOI":"10.1136\/bmj.288.6423.1084","volume":"288","author":"JL Sher","year":"1984","unstructured":"Sher JL, Stevens J, Aird EGA (1984) Relevance of osteoporosis in women with fracture of the femoral neck. Br Med J 288:1084","journal-title":"Br Med J"},{"key":"CR44","doi-asserted-by":"crossref","first-page":"1084","DOI":"10.1136\/bmj.288.6423.1084-a","volume":"288","author":"BEC Nordin","year":"1984","unstructured":"Nordin BEC (1984) Relevance of osteoporosis in women with fracture of the femoral neck. Br Med J 288:1084","journal-title":"Br Med J"},{"key":"CR45","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1136\/bmj.295.6589.13","volume":"295","author":"C Cooper","year":"1987","unstructured":"Cooper C, Barker DJP, Morris J, Briggs RSJ (1987) Osteoporosis, falls, and age in fracture of the proximal femur. Br Med J 295:13?15","journal-title":"Br Med J"},{"key":"CR46","doi-asserted-by":"crossref","unstructured":"Boyce WJ (1987) Osteoporosis, falls, and age in fracture of the proximal femur. Br Med J 295:","DOI":"10.1136\/bmj.295.6595.444-d"},{"key":"CR47","first-page":"M149","volume":"44","author":"JA Blumenthal","year":"1990","unstructured":"Blumenthal JA, Emery CF, Madden DJ, George LK, Coleman RE, Riddle MW, McKee DC, Reasoner, Williams RS (1990) Cardiovascular and behavioral effects of aerobic exercise training in healthy older men and women. J Gerontol 44:M149?154","journal-title":"J Gerontol"},{"key":"CR48","doi-asserted-by":"crossref","first-page":"859","DOI":"10.1136\/bmj.2.6091.859","volume":"2","author":"WJ MacLennan","year":"1977","unstructured":"MacLennan WJ, Hamilton JC (1977) Vitamin D supplements and 25-hydroxy vitamin D concentrations in the elderly. Br Med J 2:859?861","journal-title":"Br Med J"},{"key":"CR49","first-page":"24","volume":"10","author":"P Smith","year":"1984","unstructured":"Smith P, Barzel US (1984) Vitamin D deficiency osteomalacia in elderly persons. Compr Ther 10:24?32","journal-title":"Compr Ther"},{"key":"CR50","first-page":"91","volume":"24","author":"RP Heaney","year":"1985","unstructured":"Heaney RP, Barger-Lux MJ (1985) Calcium, bone metabolism, and structural failure. Triangle 24:91?100","journal-title":"Triangle"},{"key":"CR51","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1111\/j.1532-5415.1984.tb02050.x","volume":"32","author":"PJ Drinka","year":"1984","unstructured":"Drinka PJ, Nolten WE (1984) Hazards of treating osteoporosis and hypertension concurrently with calcium, vitamin D, and distal diuretics. J Am Geriatr Soc 32:405?407","journal-title":"J Am Geriatr Soc"},{"key":"CR52","unstructured":"Coles J, Hamdy R, Bocquet H, Stepehenson L, Downey L (1985) The treatment of biochemical osteomalacia (abstracts) XIII Intl Congr Gerontology, p 147 (New York)"},{"key":"CR53","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1016\/S0140-6736(85)91082-7","volume":"1","author":"C Garland","year":"1985","unstructured":"Garland C, Shekelle RB, Barrett-Connor E, Criqui MH, Rossof AH, Paul O (1985) Dietary vitamin D and calcium and risk of colorectal cancer: a 19-year prospective study in men. Lancet 1:307?309","journal-title":"Lancet"},{"key":"CR54","doi-asserted-by":"crossref","first-page":"1176","DOI":"10.1016\/S0140-6736(89)91789-3","volume":"2","author":"CF Garland","year":"1989","unstructured":"Garland CF, Comstock GW, Garland FC, Helsing KJ, Shaw EK, Gorham ED (1989) Serum 25-hydroxyvitamin D and colon cancer: eight-year prospective study. Lancet 2:1176?1178","journal-title":"Lancet"}],"container-title":["Calcified Tissue International"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF00298497.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/BF00298497\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF00298497","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,4,8]],"date-time":"2019-04-08T21:23:36Z","timestamp":1554758616000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/BF00298497"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1992,8]]},"references-count":54,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1992,8]]}},"alternative-id":["BF00298497"],"URL":"https:\/\/doi.org\/10.1007\/bf00298497","relation":{},"ISSN":["0171-967X","1432-0827"],"issn-type":[{"value":"0171-967X","type":"print"},{"value":"1432-0827","type":"electronic"}],"subject":[],"published":{"date-parts":[[1992,8]]}}}