{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,9,15]],"date-time":"2024-09-15T14:52:53Z","timestamp":1726411973055},"reference-count":25,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[1994,9,1]],"date-time":"1994-09-01T00:00:00Z","timestamp":778377600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["World j. surg."],"published-print":{"date-parts":[[1994,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>A group of 1127 patients who underwent sclerotherapy for esophageal varices were compared for outcome in terms of age: over and ander age 70 years. Esophageal varices were completely eradicated in 81 of 110 patients &gt;70 years (73.6%) and in 791 of 1017 patients &lt;70 years (77.8%). Gastrointestinal bleeding after sclerotherapy occurred in 9 patients &gt;70 years (8.2%) and in 84 of those &lt;70 years (8.3%). Complications occurred in 16 patients &gt;70 years (14.5%) and in 141 &lt;70 years (13.9%). Liver failure and hepatoma accounted for more than 80% of the causes of death in both groups (80.3% versus 83.8%). The 5\u2010year cumulative survival rates in patients with bleeding esophageal varices (bleeders) without hepatoma were 21.8% in those &gt;70 years and 58.7% in those &lt;70 years (<jats:italic>p<\/jats:italic>&lt;0.01), the relative survivals being 25.3% versus 66.6%. Patients without hepatoma and treated by prophylactic sclerotherapy accounted for 66.2% of patients &gt;70 years and 61.7% of those &lt;70 years, the relative survivals being 75.9% versus 71.9%. As analyzed by the Cox proportional\u2010hazards model, age &gt;70 years was a prognostic factor in the bleeders (<jats:italic>p<\/jats:italic>&lt;0.01) but not in the nonbleeders. We recommend that elderly patients with esophageal varices be given prophylactic sclerotherapy, as the outcome for these patients is poor once bleeding has occurred.<\/jats:p>","DOI":"10.1007\/bf00298925","type":"journal-article","created":{"date-parts":[[2004,10,9]],"date-time":"2004-10-09T21:34:54Z","timestamp":1097357694000},"page":"764-768","source":"Crossref","is-referenced-by-count":1,"title":["Endoscopic injection sclerotherapy for esophageal varices in the elderly"],"prefix":"10.1002","volume":"18","author":[{"given":"Masayuki","family":"Ohta","sequence":"first","affiliation":[{"name":"Department of Surgery II Faculty of Medicine Kyushu University 3\u20101\u20101\u00a0Maidashi, Higashi\u2010ku 812 Fukuoka Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Makoto","family":"Hashizume","sequence":"additional","affiliation":[{"name":"Department of Surgery II Faculty of Medicine Kyushu University 3\u20101\u20101\u00a0Maidashi, Higashi\u2010ku 812 Fukuoka Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tatsuro","family":"Kamakura","sequence":"additional","affiliation":[{"name":"Department of Surgery II Faculty of Medicine Kyushu University 3\u20101\u20101\u00a0Maidashi, Higashi\u2010ku 812 Fukuoka Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kiichiro","family":"Ueno","sequence":"additional","affiliation":[{"name":"Department of Surgery II Faculty of Medicine Kyushu University 3\u20101\u20101\u00a0Maidashi, Higashi\u2010ku 812 Fukuoka Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Morimasa","family":"Tomikawa","sequence":"additional","affiliation":[{"name":"Department of Surgery II Faculty of Medicine Kyushu University 3\u20101\u20101\u00a0Maidashi, Higashi\u2010ku 812 Fukuoka Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kazuo","family":"Tanoue","sequence":"additional","affiliation":[{"name":"Department of Surgery II Faculty of Medicine Kyushu University 3\u20101\u20101\u00a0Maidashi, Higashi\u2010ku 812 Fukuoka Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Seigo","family":"Kitano","sequence":"additional","affiliation":[{"name":"Department of Surgery II Faculty of Medicine Kyushu University 3\u20101\u20101\u00a0Maidashi, Higashi\u2010ku 812 Fukuoka Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Keizo","family":"Sugimachi","sequence":"additional","affiliation":[{"name":"Department of Surgery II Faculty of Medicine Kyushu University 3\u20101\u20101\u00a0Maidashi, Higashi\u2010ku 812 Fukuoka Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[1994,9]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9610(81)90291-9"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-2007-1013010"},{"key":"e_1_2_1_4_1","first-page":"557","volume-title":"Textbook of Geriatric Medicine and Gastroenterology","author":"Hymas D.E.","year":"1985"},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.4.5785.473"},{"key":"e_1_2_1_6_1","first-page":"323","article-title":"Results in 100 consecutive patients with stapled esophageal transection for varices","volume":"160","author":"Spence R.A.J.","year":"1985","journal-title":"Surg. 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