{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,11]],"date-time":"2025-11-11T12:40:20Z","timestamp":1762864820691},"reference-count":31,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[1992,4,1]],"date-time":"1992-04-01T00:00:00Z","timestamp":702086400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Urol. Res."],"published-print":{"date-parts":[[1992,4]]},"DOI":"10.1007\/bf00299716","type":"journal-article","created":{"date-parts":[[2004,10,8]],"date-time":"2004-10-08T16:05:19Z","timestamp":1097251519000},"page":"193-197","source":"Crossref","is-referenced-by-count":16,"title":["Differential sensitivity of hormone-responsive and unresponsive human prostate cancer cells (LNCaP) to tumor necrosis factor"],"prefix":"10.1007","volume":"20","author":[{"given":"X.","family":"Zhao","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G. J.","family":"van Steenbrugge","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F. H.","family":"Schr\u00f6der","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"CR1","first-page":"6389","volume":"50","author":"H Baisch","year":"1990","unstructured":"Baisch H, Otto U, Kl\u00f6ppel G (1990) Antiproliferative and cytotoxic effects of single and combined treatment with tumor necrosis factor ? and\/or ? interferon on a human renal cell carcinoma xenotransplanted into nu\/nu mice: cell kinetic studies. Cancer Res 50:6389","journal-title":"Cancer Res"},{"key":"CR2","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1007\/BF00263641","volume":"16","author":"AJMC Beniers","year":"1988","unstructured":"Beniers AJMC Peelen WP, Hendriks BT, Schalken JA, Romijn JC, Debruyne FMJ (1988) In vitro antiproliferative efficacy of interferon-alpha,-gamma and tumor necrosis factor on two human renal tumor xenografts. Urol Res 16: 309","journal-title":"Urol Res"},{"key":"CR3","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1007\/BF00368183","volume":"19","author":"AJMC Beniers","year":"1991","unstructured":"Beniers AJMC, Moorselaar RJA van, Peelen WP, Debruyne FMJ, Schalken JA (1991) Differential sensitivity of renal cell carcinoma xenografts towards therapy with interferon-alpha, interferon-gamma, tumor necrosis factor and their combinations. Urol Res 19: 91","journal-title":"Urol Res"},{"key":"CR4","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1002\/pros.2990090305","volume":"9","author":"EMJJ Berns","year":"1986","unstructured":"Berns EMJJ, Boer W de, Mulder M (1986) Androgen dependent growth regulation of and the release of specific protein (s) by the androgen receptor containing human prostate tumor cell line LNCaP. Prostate 9: 247","journal-title":"Prostate"},{"key":"CR5","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1042\/bj1330529","volume":"133","author":"AE Bolton","year":"1973","unstructured":"Bolton AE, Hunter WM (1973) The labelling of proteins to high specific radioactivities by conjugation to a 125I-containing acylating agent: application to the radio-immunoassay. Biochem J 133: 529","journal-title":"Biochem J"},{"key":"CR6","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1016\/S0039-128X(75)80023-7","volume":"26","author":"C Bonne","year":"1976","unstructured":"Bonne C, Raynaud JP (1976) Methyltrienolone, a specific ligand for cellular androgen receptors. Steroids 26: 227","journal-title":"Steroids"},{"key":"CR7","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1182\/blood.V74.2.565.565","volume":"74","author":"LM Budel","year":"1989","unstructured":"Budel LM, Touw JP, Delwel R, Clark SC, L\u00f6wenberg B (1989) Interleukin-3 and granulocyte-monocyte colony-stimulating factor receptors on human acute myelocytic leukemia cells and relationship to the proliferative response. Blood 74: 565","journal-title":"Blood"},{"key":"CR8","first-page":"209","volume":"16","author":"JM Connolly","year":"1990","unstructured":"Connolly JM, Rose DP (1990) Production of epidermal growth factor and transforming growth factor-? by the androgen-responsive LNCaP human prostate cancer cell line. Proctate 16: 209","journal-title":"Proctate"},{"key":"CR9","first-page":"56","volume":"32","author":"NJ Donato","year":"1991","unstructured":"Donato NJ, Vijjeswarapu D, Rosenblum MG (1991) Expression and rapid phosphorylation of EGF receptor correlate with TNF-responsiveness in human cervical carcinoma cells. Proc Am Assoc Cancer Res 32: 56","journal-title":"Proc Am Assoc Cancer Res"},{"key":"CR10","doi-asserted-by":"crossref","first-page":"1206","DOI":"10.1093\/jnci\/82.14.1206","volume":"82","author":"JP Fruehauf","year":"1990","unstructured":"Fruehauf JP, Myers CE, Sinha BK (1990) Synergistic activity of suramin with tumor necrosis factor ? and doxorubincin on human prostate cancer cell lines. Natl Cancer Inst 82: 1206","journal-title":"Natl Cancer Inst"},{"key":"CR11","first-page":"191","volume":"51","author":"K Haranaka","year":"1981","unstructured":"Haranaka K, Satomi N (1981) Cytotoxic activity of human necrosis factor (TNF) on human cancer cells in vitro. Jpn J Exp Med 51: 191","journal-title":"Jpn J Exp Med"},{"key":"CR12","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1002\/ijc.2910340219","volume":"34","author":"K Haranaka","year":"1984","unstructured":"Haranaka K, Satomi N, Sakurai A (1984) Antitumor activity o murine tumor necrosis factor (TNF) against transplanted murine tumors and heterotransplanted human tumors in nude mice. Int J Cancer 34: 263","journal-title":"Int J Cancer"},{"key":"CR13","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1002\/pros.2990070208","volume":"7","author":"M Hasenson","year":"1985","unstructured":"Hasenson M, Hartley-Asp B, Kihlfors C, Lundin A, Gustafsson J-\u00c5, Pousette \u00c5 (1985) Effect of hormones on growth and ATP content of a human prostatic carcinoma cell line, LNCaP-r. Prostate 7: 183","journal-title":"Prostate"},{"key":"CR14","first-page":"357","volume":"16","author":"M Hasenson","year":"1988","unstructured":"Hasenson M, Lundh B, Hartley-Asp B, Pousette \u00c5 (1988) Growth inhibiting effect of estramustine on two prostatic carcinoma cell lines, LNCaP and LNCaP-r. Urol Res 16: 357","journal-title":"Urol Res"},{"key":"CR15","first-page":"115","volume":"37","author":"JS Horoszewicz","year":"1980","unstructured":"Horoszewicz JS, Leong S, Chu T, Wajsman Z, Friedman M, Papsidero L, Kim U, Chiu L, Kakati S, Arya S, Sandberg A (1980) The LNCaP cell line?a new model for studies on human prostatic carcinoma. Prog Clin Biol Res 37: 115","journal-title":"Prog Clin Biol Res"},{"key":"CR16","first-page":"1809","volume":"43","author":"JS Horoszewicz","year":"1983","unstructured":"Horoszewicz JS, Leong S, Kawinski E, Karr J, Rosenthal H, Chu TM, Mirand EA, Murphy GP (1983) LNCaP model of huma prostatic carcinoma. Cancer Res 43: 1809","journal-title":"Cancer Res"},{"key":"CR17","first-page":"293","volume":"1","author":"C Huggins","year":"1941","unstructured":"Huggins C, Hodges CV (1941) Studies on prostatic cancer. I. The effect of castration, of estrogen and of androgen injection on serum phosphatases in metastatic carcinoma of the prostate. Cancer Res 1: 293","journal-title":"Cancer Res"},{"key":"CR18","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1007\/BF00254424","volume":"15","author":"JT Isaacs","year":"1987","unstructured":"Isaacs JT, Kyprianou N (1987) Development of androgenindependent tumor cells and their implantation for the treatment of prostatic cancer. Urol Res 15: 133","journal-title":"Urol Res"},{"key":"CR19","doi-asserted-by":"crossref","first-page":"231","DOI":"10.3109\/00365597709179957","volume":"11","author":"G J\u00f6nsson","year":"1977","unstructured":"J\u00f6nsson G, H\u00f6gberg B, Nilsson T (1977) Treatment of advanced prostatic carcinoma with estramustine phosphate. Scand Urol Nephrol 11: 231","journal-title":"Scand Urol Nephrol"},{"key":"CR20","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1007\/BF00262025","volume":"17","author":"JJ K\u00f6nig","year":"1989","unstructured":"K\u00f6nig JJ, Kamst E, Hagemeijer A, Romijn JC, Horoszewicz J, Schr\u00f6der FH (1989) Cytogenetic characterization of several androgen responsive and unresponsive sublines of the human prostatic carcinoma cell line LNCaP. Urol Res 17: 79","journal-title":"Urol Res"},{"key":"CR21","doi-asserted-by":"crossref","first-page":"552","DOI":"10.1210\/endo-122-2-552","volume":"122","author":"N Kyprianou","year":"1988","unstructured":"Kyprianou N, Isaacs JT (1988) Activation of programmed cell death in the rat ventral prostate after castration. Endocrinology 122: 552","journal-title":"Endocrinology"},{"key":"CR22","doi-asserted-by":"crossref","first-page":"3215","DOI":"10.1096\/fasebj.4.14.2172061","volume":"4","author":"JW Larrick","year":"1990","unstructured":"Larrick JW, Wright SC (1990) Cytotoxic mechanism of tumor necrosis factor-?. FASEB J 4: 3215","journal-title":"FASEB J"},{"key":"CR23","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1016\/S0022-5347(17)38350-7","volume":"145","author":"S Liu","year":"1991","unstructured":"Liu S, Ewing MW, Anglard P, Trahan E, La Rocca RV, Myers CE, Linehan WM (1991) The effect of suramin, tumor necrosis factor and interferon-? on human prostate carcinoma. J Urol 145: 389","journal-title":"J Urol"},{"key":"CR24","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/0022-1759(83)90303-4","volume":"65","author":"T Mosmann","year":"1983","unstructured":"Mosmann T (1983) Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J Immunol Methods 65: 55","journal-title":"J Immunol Methods"},{"key":"CR25","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1002\/pros.2990120112","volume":"12","author":"JC Romijn","year":"1988","unstructured":"Romijn JC, Verkoelen CF, Schroeder FH (1988) Application of the MTT assay to human prostate cancer cell lines in vitro: establishment of test conditions and assessment of hormone-stimulated growth and drug-induced cytostatic and cytotoxic effects. Prostate 12: 99","journal-title":"Prostate"},{"key":"CR26","first-page":"6006","volume":"48","author":"BY Rubin","year":"1988","unstructured":"Rubin BY, Smith LJ, Hellerman GR, Lunn RM, Richardson NK, Anderson SL (1988) A correlation between the anticellular and DNA fragmenting activities of tumor necrosis factor. Cancer Res 48: 6006","journal-title":"Cancer Res"},{"key":"CR27","first-page":"44","volume":"9","author":"ER Sherwood","year":"1990","unstructured":"Sherwood ER, Ford TR, Lee C, Kozlowski JM (1990) Therapeutic efficacy of recombinant tumor necrosis factor ? in an experimental model of human prostatic carcinoma. J Biol Response Mod 9: 44","journal-title":"J Biol Response Mod"},{"key":"CR28","first-page":"12","volume":"39","author":"E Silverberg","year":"1989","unstructured":"Silverberg E, Lubera A (1989) Cancer statistics, 1989. CA 39: 12","journal-title":"CA"},{"key":"CR29","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1007\/BF00262024","volume":"17","author":"GJ Steenbrugge van","year":"1989","unstructured":"Steenbrugge GJ van, Groen M, Dongen JW van, Bolt J, Korput H van der, Trapman J, Hasenson M, Horoszewicz J (1989) The human prostatic carcinoma cell line LNCaP and its derivatives: an overview. Urol Res 17: 71","journal-title":"Urol Res"},{"key":"CR30","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1016\/0960-0760(91)90184-7","volume":"40","author":"GJ Steenbrugge van","year":"1991","unstructured":"Steenbrugge GJ van, Uffelen CJC van, Bolt J, Schr\u00f6der FH (1991) The human prostatic cancer cell line LNCaP and its derived sublines: an in vitro model for the study of androgen-sensitivity. J Steroid Biochem Mol Biol 40: 207","journal-title":"J Steroid Biochem Mol Biol"},{"key":"CR31","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/S0094-0143(21)01062-4","volume":"2","author":"PC Walsh","year":"1975","unstructured":"Walsh PC (1975) Physiologic basis for hormonal therapy in carcinoma of the prostate. Urol Clin North Am 2: 125","journal-title":"Urol Clin North Am"}],"container-title":["Urological Research"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF00299716.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/BF00299716\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF00299716","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,6,26]],"date-time":"2021-06-26T08:46:38Z","timestamp":1624697198000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/BF00299716"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1992,4]]},"references-count":31,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1992,4]]}},"alternative-id":["BF00299716"],"URL":"https:\/\/doi.org\/10.1007\/bf00299716","relation":{},"ISSN":["0300-5623","1434-0879"],"issn-type":[{"value":"0300-5623","type":"print"},{"value":"1434-0879","type":"electronic"}],"subject":[],"published":{"date-parts":[[1992,4]]}}}