{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T05:09:03Z","timestamp":1791263343712,"version":"4.1.0"},"reference-count":29,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[1993,7,1]],"date-time":"1993-07-01T00:00:00Z","timestamp":741484800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cell Tissue Res"],"published-print":{"date-parts":[[1993,7]]},"DOI":"10.1007\/bf00304610","type":"journal-article","created":{"date-parts":[[2004,10,9]],"date-time":"2004-10-09T23:47:29Z","timestamp":1097365649000},"page":"41-52","source":"Crossref","is-referenced-by-count":53,"title":["The basement membranes of cryofixed or aldehyde-fixed, freeze-substituted tissues are composed of a lamina densa and do not contain a lamina lucida"],"prefix":"10.1007","volume":"273","author":[{"given":"Franky Leung","family":"Chan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sadayuki","family":"Inoue","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charles Philippe","family":"Leblond","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"CR1","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1002\/path.1711490402","volume":"149","author":"DR Abrahamson","year":"1986","unstructured":"Abrahamson DR (1986) Recent studies on the structure and pathology of basement membranes. J Pathol 149:257?278","journal-title":"J Pathol"},{"key":"CR2","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1002\/pros.2990140208","volume":"14","author":"FL Chan","year":"1989","unstructured":"Chan FL, Wong YC (1989) Ultrastructural localization of proteoglycans by cationic dyes in the epithelial-stroma interface of the guinea pig lateral prostate. Prostate 14:147?162","journal-title":"Prostate"},{"key":"CR3","doi-asserted-by":"crossref","first-page":"1807","DOI":"10.1177\/40.11.1431067","volume":"40","author":"FL Chan","year":"1992","unstructured":"Chan FL, Inoue S, Leblond CP (1992) Localization of heparan sulfate proteoglycan in basement membranes. J Histochem Cytochem 40:1807?1808","journal-title":"J Histochem Cytochem"},{"key":"CR4","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1002\/ar.1092350203","volume":"235","author":"FL Chan","year":"1993","unstructured":"Chan FL, Inoue S, Leblond CP (1993) Cryofixation of basement membranes followed by freeze substitution or freeze drying demonstrates that they are composed of a tridimensional network of irregular cords. Anat Rec 235:191?205","journal-title":"Anat Rec"},{"key":"CR5","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1083\/jcb.87.3.691","volume":"87","author":"PJ Courtoy","year":"1980","unstructured":"Courtoy PJ, Kanwar YS, Hynes RO, Farquhar MG (1980) Fibronectin localization in the rat glomerulus. J Cell Biol 87:691?696","journal-title":"J Cell Biol"},{"key":"CR6","first-page":"1","volume-title":"Techniques in immunocytochemistry, vol 4","author":"HY Elder","year":"1989","unstructured":"Elder HY (1989) Cryofixation. In: Bullock GR, Pretusz P (eds) Techniques in immunocytochemistry, vol 4. Academic Press, San Diego, pp 1?28"},{"key":"CR7","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1007\/978-1-4613-0881-2_12","volume-title":"Cell biology of the extracellular matrix","author":"MG Farquhar","year":"1981","unstructured":"Farquhar MG (1981) The glomerular basement membrane. A selective macromolecular filter. In: Hay ED (ed) Cell biology of the extracellular matrix. Plenum Press, New York, pp 335?378"},{"key":"CR8","first-page":"336","volume":"42","author":"JM Foidart","year":"1980","unstructured":"Foidart JM, Bere EW Jr, Yaar M, Rennard SI, Gullino M, Martin GR, Katz SI (1980) Distribution and immunoelectron microscopic localization of laminin, a noncollagenous basement membrane glycoprotein. Lab Invest 42:336?342","journal-title":"Lab Invest"},{"key":"CR9","first-page":"365","volume":"42","author":"M Goldberg","year":"1986","unstructured":"Goldberg M, Escaig-Haye F (1986) Is the lamina lucida of the basement membrane a fixation artefact? Eur J Cell Biol 42:365?368","journal-title":"Eur J Cell Biol"},{"key":"CR10","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1002\/aja.1001740403","volume":"174","author":"DS Grant","year":"1985","unstructured":"Grant DS, Kleinman HK, Leblond CP, Inoue S, Chung AE, Martin GR (1985) The basement-membrane-like matrix of the mouse EHS tumor. II. Immunohistochemical quantitation of six of its components. Am J Anat 174:387?398","journal-title":"Am J Anat"},{"key":"CR11","first-page":"2713","volume":"45","author":"PH Hand","year":"1985","unstructured":"Hand PH, Thor A, Schlom J, Rao CN, Liotta A (1985) Expression of laminin receptors in normal and carcinomatous human tissue as defined by a monoclonal antibody. Cancer Res 45:2713?2719","journal-title":"Cancer Res"},{"key":"CR12","volume-title":"Biology of Carbohydrates","author":"VC Hascall","year":"1981","unstructured":"Hascall VC (1981) Proteoglycan: structure and function. In: Ginsburg V (ed) Biology of Carbohydrates. Wiley, New York, p 1"},{"key":"CR13","first-page":"184","volume-title":"Principles and Techniques of Electron Microscopy. Biological Applications, vol 1","author":"MA Hayat","year":"1970","unstructured":"Hayat MA (1970) Principles and Techniques of Electron Microscopy. Biological Applications, vol 1. Van Nostrand Reinhold, New York, pp 184?189"},{"key":"CR14","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/S0074-7696(08)61334-0","volume":"117","author":"S Inoue","year":"1989","unstructured":"Inoue S (1989) Ultrastructure of basement membranes. Int Rev Cytol 117:57?98","journal-title":"Int Rev Cytol"},{"key":"CR15","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1002\/aja.1001810403","volume":"181","author":"S Inoue","year":"1988","unstructured":"Inoue S, Leblond CP (1988) Three-dimensional network of cords: the main component of basement membranes. Am J Anat 181:341?358","journal-title":"Am J Anat"},{"key":"CR16","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1083\/jcb.81.1.137","volume":"81","author":"YS Kanwar","year":"1979","unstructured":"Kanwar YS, Farquhar MG (1979) Anionic sites in the glomerular basement membrane. In vivo and in vitro localization to the lamina rara by cationic probes. J Cell Biol 81:137?153","journal-title":"J Cell Biol"},{"key":"CR17","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1016\/S0074-7696(08)61998-1","volume":"61","author":"NA Kefalides","year":"1979","unstructured":"Kefalides NA, Alper R, Clark CC (1979) Biochemistry and metabolism of basement membranes. Int Rev Cytol 61:167?228","journal-title":"Int Rev Cytol"},{"key":"CR18","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1002\/aja.1001690408","volume":"169","author":"GW Laurie","year":"1984","unstructured":"Laurie GW, Leblond CP, Inoue S, Martin GR, Chung A (1984) Fine structure of the glomerular basement membrane and immunolocalization of five basement membrane components to the lamina densa (basal lamina) and its extensions in both glomeruli and tubules of the rat kidney. Am J Anat 169:463?481","journal-title":"Am J Anat"},{"key":"CR19","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1002\/aja.1001850403","volume":"185","author":"CP Leblond","year":"1989","unstructured":"Leblond CP, Inoue S (1989) Structure, composition, and assembly of basement membrane. Am J Anat 185:367?390","journal-title":"Am J Anat"},{"key":"CR20","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/0014-4827(85)90266-6","volume":"156","author":"LA Liotta","year":"1985","unstructured":"Liotta LA, Hand PH, Rao CH, Bryant G, Barsky SH, Schlom J (1985) Monoclonal antibodies to the human laminin receptor recognize structurally distinct sites. Exp Cell Res 156:117?126","journal-title":"Exp Cell Res"},{"key":"CR21","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1002\/ar.1091710302","volume":"171","author":"JH Luft","year":"1971","unstructured":"Luft JH (1971) Ruthenium red and violet. I. Chemistry, purification, methods of use for electron microscopy and mechanism of action. Anat Rec 171:347?368","journal-title":"Anat Rec"},{"key":"CR22","doi-asserted-by":"crossref","first-page":"682","DOI":"10.1083\/jcb.86.2.682","volume":"86","author":"JA Madri","year":"1980","unstructured":"Madri JA, Roll J, Furthmayr H, Foidart JM (1980) Ultrastructural localization of fibronectin and laminin in the basement membrane of the murine kidney. J Cell Biol 86:682?687","journal-title":"J Cell Biol"},{"key":"CR23","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1083\/jcb.32.1.27","volume":"32","author":"A Rambourg","year":"1967","unstructured":"Rambourg A, Leblond CP (1967) Electron microscope observations on the carbohydrate-rich cell coat present at the surface of cells in the rat. J Cell Biol 32:27?53","journal-title":"J Cell Biol"},{"key":"CR24","first-page":"32","volume-title":"Hereditary Nephritis. Contrib Nephrol, vol 80","author":"E Reale","year":"1990","unstructured":"Reale E, Luciano L (1990) The laminae rarae of the glomerular basement membrane. Their manifestation depends on the histochemical and histological techniques. In: Sessa A, Meroni M, Battini G (eds) Hereditary Nephritis. Contrib Nephrol, vol 80. Karger, Basel, pp 32?40"},{"key":"CR25","doi-asserted-by":"crossref","first-page":"887","DOI":"10.1042\/bj1870887","volume":"187","author":"JE Scott","year":"1980","unstructured":"Scott JE (1980) Collage-proteoglycan interaction: localization of proteoglycan in tendon by electron microscopy. Biochem J 187:887?891","journal-title":"Biochem J"},{"key":"CR26","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1016\/S0174-173X(85)80008-X","volume":"5","author":"JE Scott","year":"1985","unstructured":"Scott JE (1985) Proteoglycan histochemistry ? a valuable tool for connective tissue biochemists. Collagen Rel Res 5:541?575","journal-title":"Collagen Rel Res"},{"key":"CR27","doi-asserted-by":"crossref","first-page":"815","DOI":"10.1083\/jcb.62.3.815","volume":"62","author":"RL Trelstad","year":"1974","unstructured":"Trelstad RL, Hayashi K, Toole BP (1974) Epithelial collagens and glycosaminoglycans in the embryonic cornea. Macromolecular order and morphogenesis in the basement membrane. J Cell Biol 62:815?830","journal-title":"J Cell Biol"},{"key":"CR28","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1111\/1523-1747.ep12541313","volume":"70","author":"H Yaoita","year":"1978","unstructured":"Yaoita H, Foidart JM, Katz SJ (1978) Localization of the collagenous component in skin basement membrane. J Invest Dermatol 70:191?193","journal-title":"J Invest Dermatol"},{"key":"CR29","doi-asserted-by":"crossref","first-page":"1577","DOI":"10.1096\/fasebj.4.6.2180767","volume":"4","author":"PD Yurchenco","year":"1990","unstructured":"Yurchenco PD, Schittny JC (1990) Molecular architecture of basement membranes. FASEB J 4:1577?1590","journal-title":"FASEB J"}],"container-title":["Cell and Tissue Research"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF00304610.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/BF00304610\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF00304610","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,4,8]],"date-time":"2019-04-08T16:51:27Z","timestamp":1554742287000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/BF00304610"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1993,7]]},"references-count":29,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1993,7]]}},"alternative-id":["BF00304610"],"URL":"https:\/\/doi.org\/10.1007\/bf00304610","relation":{},"ISSN":["0302-766X","1432-0878"],"issn-type":[{"value":"0302-766X","type":"print"},{"value":"1432-0878","type":"electronic"}],"subject":[],"published":{"date-parts":[[1993,7]]}}}