{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,5]],"date-time":"2026-08-05T04:50:18Z","timestamp":1785905418097,"version":"3.56.0"},"reference-count":39,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[1976,1,1]],"date-time":"1976-01-01T00:00:00Z","timestamp":189302400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Neurol."],"published-print":{"date-parts":[[1976]]},"DOI":"10.1007\/bf00313269","type":"journal-article","created":{"date-parts":[[2004,10,10]],"date-time":"2004-10-10T16:20:52Z","timestamp":1097425252000},"page":"79-85","source":"Crossref","is-referenced-by-count":6,"title":["Studies on the geographic clustering of multiple sclerosis and optic neuritis in Finland"],"prefix":"10.1007","volume":"213","author":[{"given":"Juhani","family":"Wikstr\ufffdm","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jorma","family":"Palo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"CR1","first-page":"3","volume-title":"The epidemiology of multiple sclerosis. A reappraisal","author":"E. D. Acheson","year":"1972","unstructured":"Acheson, E. D.: The epidemiology of multiple sclerosis. A reappraisal (eds. D. McAlpine, C. E. Lumsden, E. D. Acheson), 2nd ed., pp. 3?80. London: Churchill Livingstone 1972","edition":"2nd ed."},{"key":"CR2","doi-asserted-by":"crossref","first-page":"631","DOI":"10.1212\/WNL.23.6.631","volume":"23","author":"M. Alter","year":"1973","unstructured":"Alter, M., Good, J., Okihiro, M.: Optic neuritis in Orientals and Caucasians. Neurology (Minneap.) 23, 631?639 (1973)","journal-title":"Neurology"},{"key":"CR3","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1159\/000114414","volume":"7","author":"J. Bertrams","year":"1972","unstructured":"Bertrams, J., Kuwert, E.: HL-A antigen frequencies in multiple sclerosis. Significant increase of HL-A3, HL-A10 and W5, and decrease of HL-A12. Europ. Neurol. 7, 74?78 (1972)","journal-title":"Europ. Neurol."},{"key":"CR4","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1136\/jnnp.31.1.10","volume":"31","author":"W. G. Bradley","year":"1968","unstructured":"Bradley, W. G., Whitty, C. W. M.: Acute optic neuritis: prognosis for development of multiple sclerosis. J. Neurol. Neurosurg. Psychiat. 31, 10?18 (1968)","journal-title":"J. Neurol. Neurosurg. Psychiat."},{"key":"CR5","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1111\/j.1600-0404.1973.tb01338.x","volume":"49","author":"H. Dassel","year":"1973","unstructured":"Dassel, H.: The mortality from multiple sclerosis in the Netherlands. Acta neurol. scand. 49, 659?674 (1973)","journal-title":"Acta neurol. scand."},{"key":"CR6","first-page":"197","volume-title":"On the risk of multiple sclerosis according to age at immigration. Multiple sclerosis. Progress in research","author":"G. Dean","year":"1972","unstructured":"Dean, G.: On the risk of multiple sclerosis according to age at immigration. Multiple sclerosis. Progress in research (eds. E. J. Field, T. M. Bell, P. R. Carnegie), pp. 197?203. Amsterdam: North-Holland Publ. Co. 1972"},{"issue":"130","key":"CR7","first-page":"7","volume":"31","author":"T. O. Diener","year":"1973","unstructured":"Diener, T. O.: Similarities between the scrapie agent and the agent of the potato spindle tuber disease. Scand. J. clin. Lab. Invest. 31, Suppl. 130, 7 (1973)","journal-title":"Scand. J. clin. Lab. Invest."},{"issue":"25","key":"CR8","first-page":"1","volume":"46","author":"T. Fog","year":"1970","unstructured":"Fog, T., Linneman, F.: The course of multiple sclerosis. Acta neurol. scand. 46, Suppl. 25, 1?175 (1970)","journal-title":"Acta neurol. scand."},{"issue":"147","key":"CR9","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1111\/j.1600-0447.1960.tb08666.x","volume":"42","author":"F. Georgi","year":"1960","unstructured":"Georgi, F., Hall, P.: Studies on multiple sclerosis frequency in Switzerland and East Africa. Acta psychiat. neurol. scand. 42, Suppl. 147, 75?84 (1960)","journal-title":"Acta psychiat. neurol. scand."},{"key":"CR10","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1111\/j.1749-6632.1972.tb27853.x","volume":"203","author":"J. Green","year":"1972","unstructured":"Green, J.: Vitamin E and the biological antioxidant theory. Ann. N.Y. Acad. Sci. 203, 29?44 (1972)","journal-title":"Ann. N.Y. Acad. Sci."},{"key":"CR11","volume-title":"Disseminated sclerosis in Denmark. Prevalence and geographical distribution","author":"K. Hyllested","year":"1956","unstructured":"Hyllested, K.: Disseminated sclerosis in Denmark. Prevalence and geographical distribution. Dissertation, Copenhagen 1956"},{"key":"CR12","doi-asserted-by":"crossref","first-page":"1221","DOI":"10.1016\/S0140-6736(73)90970-7","volume":"II","author":"C. Jersild","year":"1973","unstructured":"Jersild, C., Fog, T., Hansen, G. S., Thomsen, M., Svejgaard, A., Dupont, B.: Histocompatibility determinants in multiple sclerosis with special reference to clinical course. Lancet 1973 II, 1221?1224","journal-title":"Lancet"},{"key":"CR13","doi-asserted-by":"crossref","unstructured":"Jokelainen, M., Palo, J., Wikstr\u00f6m, J.: The distribution of amyotrophic lateral sclerosis in Finland. J. neurol. Sci. 473?479 (1975)","DOI":"10.1016\/0022-510X(75)90266-X"},{"key":"CR14","doi-asserted-by":"crossref","first-page":"845","DOI":"10.1212\/WNL.25.9.845","volume":"25","author":"Y. Kuroiwa","year":"1975","unstructured":"Kuroiwa, Y., Igata, A., Itahara, K., Koshijima, S., Tsubaki, T., Toyokura, Y., Shibasaki, H.: Nationwide survey of multiple sclerosis in Japan. Clinical analysis of 1,084 cases. Neurology (Minneap.) 25, 845?851 (1975)","journal-title":"Neurology"},{"key":"CR15","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1111\/j.1600-0404.1965.tb04286.x","volume":"41","author":"J. F. Kurtzke","year":"1965","unstructured":"Kurtzke, J. F.: Familial incidence and geography in multiple sclerosis. Acta neurol. scand. 41, 127?139 (1965)","journal-title":"Acta neurol. scand."},{"issue":"19","key":"CR16","first-page":"91","volume":"42","author":"J. F. Kurtzke","year":"1966","unstructured":"Kurtzke, J. F.: An evaluation of the geographic distribution of multiple sclerosis. Acta neurol. scand. 42, Suppl. 19, 91?117 (1966)","journal-title":"Acta neurol. scand."},{"key":"CR17","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1111\/j.1600-0404.1967.tb05734.x","volume":"43","author":"J. F. Kurtzke","year":"1967","unstructured":"Kurtzke, J. F.: Further consideration of the geographic distribution of multiple sclerosis. Acta neurol. scand. 43, 283?298 (1967)","journal-title":"Acta neurol. scand."},{"key":"CR18","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1111\/j.1600-0404.1975.tb01364.x","volume":"51","author":"J. F. Kurtzke","year":"1975","unstructured":"Kurtzke, J. F.: A reassessment of the distribution of multiple sclerosis. Part One. Acta neurol. scand. 51, 110?136 (1975)","journal-title":"Part One. Acta neurol. scand."},{"key":"CR19","first-page":"179","volume-title":"Population studies of multiple sclerosis in Israel. Multiple sclerosis. Progress in research","author":"U. Leibowitz","year":"1972","unstructured":"Leibowitz, U., Kahana, E., Alter, M.: Population studies of multiple sclerosis in Israel. Multiple sclerosis. Progress in research (eds. E. J. Field, T. M. Bell, P. R. Carnegie), pp. 179?196. Amsterdam: North-Holland Publ. Co. 1972"},{"key":"CR20","first-page":"82","volume-title":"Some aspects of the natural history. Multiple sclerosis. A reappraisal","author":"D. McAlpine","year":"1972","unstructured":"McAlpine, D.: Some aspects of the natural history. Multiple sclerosis. A reappraisal (eds. D. McAlpine, C. E. Lumsden, E. D. Acheson), pp. 82?131. London: Churchill Livingstone 1972"},{"key":"CR21","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0140-6736(72)91273-1","volume":"II","author":"V. Meulen ter","year":"1972","unstructured":"ter Meulen, V., Koprowski, H., Iwasaki, Y., K\u00e4ckell, Y. N., M\u00fcller, D.: Fusion of cultured multiple-sclerosis brain cells with indicator cells: presence of nucleocapsids and virions and isolation of parainfluenza-type virus. Lancet 1972 II, 1?5","journal-title":"Lancet"},{"key":"CR22","doi-asserted-by":"crossref","first-page":"765","DOI":"10.1136\/bmj.1.5856.765","volume":"I","author":"J. H. D. Millar","year":"1973","unstructured":"Millar, J. H. D., Zilkha, K. J., Langman, M. J. S., Payling Wright, H., Smith, A. D., Belin, J., Thompson, R. H. S.: A double-blind trial of linoleate supplementation of the diet in multiple sclerosis. Brit. med. J. 1973 I, 765?768","journal-title":"Brit. med. J."},{"key":"CR23","doi-asserted-by":"crossref","first-page":"1147","DOI":"10.1016\/S0140-6736(67)90650-2","volume":"II","author":"P. R. Millard","year":"1967","unstructured":"Millard, P. R., Mitchinson, M. J.: Swayback and multiple sclerosis. Lancet 1967 II, 1147","journal-title":"Lancet"},{"key":"CR24","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1212\/WNL.24.7.673","volume":"24","author":"M. Morariu","year":"1974","unstructured":"Morariu, M., Alter, M., Harshe, M.: Multiple sclerosis in Transylvania: a zone of transition in frequency. Neurology (Minneap.) 24, 673?679 (1974)","journal-title":"Neurology"},{"key":"CR25","doi-asserted-by":"crossref","first-page":"690","DOI":"10.1111\/j.1600-0404.1974.tb02815.x","volume":"50","author":"E. Nikoskelainen","year":"1974","unstructured":"Nikoskelainen, E., Riekkinen, P.: Optic neuritis ? a sign of multiple sclerosis or other diseases of the central nervous system. A retrospective analysis of 116 patients. Acta neurol. scand. 50, 690?718 (1974)","journal-title":"Acta neurol. scand."},{"key":"CR26","first-page":"109","volume":"5","author":"R. Norio","year":"1973","unstructured":"Norio, R., Nevanlinna, H. R., Perheentupa, J.: Hereditary diseases in Finland; rare flora in rare soil. Ann. Clin. Res. 5, 109?141 (1973)","journal-title":"Ann. Clin. Res."},{"key":"CR27","unstructured":"Palo, J., Duchesne, J., Wikstr\u00f6m, J.: Malignant diseases among patients with multiple sclerosis. In preparation"},{"key":"CR28","doi-asserted-by":"crossref","first-page":"848","DOI":"10.1016\/S0140-6736(73)90892-1","volume":"II","author":"J. Palo","year":"1973","unstructured":"Palo, J., Wikstr\u00f6m, J., Kivalo, E.: Epidemiology of nutritional muscular dystrophy and multiple sclerosis. Letter to the editor. Lancet 1973 II, 848","journal-title":"Lancet"},{"issue":"39","key":"CR29","first-page":"1","volume":"45","author":"M. Panelius","year":"1969","unstructured":"Panelius, M.: Studies on epidemiological, clinical, and aetiological aspects of multiple sclerosis. Acta neurol. scand. 45, Suppl. 39, 1?82 (1969)","journal-title":"Acta neurol. scand."},{"key":"CR30","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1111\/j.1600-0404.1973.tb01281.x","volume":"49","author":"M. Panelius","year":"1973","unstructured":"Panelius, M., Salmi, A., Halonen, P. E., Kivalo, E., Rinne, U. K., Penttinen, K.: Virus antibodies in serum specimens from patients with multiple sclerosis, from siblings, and matched controls. A final report. Acta neurol. scand. 49, 85?107 (1973)","journal-title":"Acta neurol. scand."},{"key":"CR31","first-page":"218","volume":"28","author":"J. Prineas","year":"1972","unstructured":"Prineas, J.: Paramyxovirus-like particles associated with acute demyelination in chronic relapsing multiple sclerosis. J. Neurol. Neurosurg. Psychiat. 28, 218?222 (1972)","journal-title":"J. Neurol. Neurosurg. Psychiat."},{"key":"CR32","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1111\/j.1600-0404.1966.tb01191.x","volume":"42","author":"U. K. Rinne","year":"1966","unstructured":"Rinne, U. K., Panelius, M., Kivalo, E., Hokkanen, E., Palo, J.: Distribution of multiple sclerosis in Finland, with special reference to some geological factors. Acta neurol. scand. 42, 385?399 (1966)","journal-title":"Acta neurol. scand."},{"key":"CR33","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1093\/brain\/79.4.635","volume":"79","author":"J. M. Sutherland","year":"1956","unstructured":"Sutherland, J. M.: Observations on the prevalence of multiple sclerosis in northern Scotland. Brain 79, 635?654 (1956)","journal-title":"Brain"},{"key":"CR34","doi-asserted-by":"crossref","first-page":"721","DOI":"10.1056\/NEJM195205082461901","volume":"246","author":"R. L. Swank","year":"1952","unstructured":"Swank, R. L., Lerstad, O., Str\u00f6m, A., Backer, J.: Multiple sclerosis in rural Norway. Its geographic and occupational incidence in relation to nutrition. New Engl. J. Med. 246, 721?728 (1952)","journal-title":"New Engl. J. Med."},{"key":"CR35","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1111\/j.1600-0404.1975.tb07598.x","volume":"51","author":"J. Wikstr\u00f6m","year":"1975","unstructured":"Wikstr\u00f6m, J.: Studies on the clustering of multiple sclerosis in Finland. II: microepidemiology in one highrisk county with special reference to familial cases. Acta neurol. scand. 51, 173?183 (1975a)","journal-title":"Acta neurol. scand."},{"key":"CR36","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1111\/j.1600-0404.1975.tb05775.x","volume":"52","author":"J. Wikstr\u00f6m","year":"1975","unstructured":"Wikstr\u00f6m, J.: The epidemiology of multiple sclerosis and tuberculosis in Finland. A study based on mortality statistics. Acta neurol. scand. 52, 207?215 (1975b)","journal-title":"Acta neurol. scand."},{"key":"CR37","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1111\/j.1600-0404.1975.tb05774.x","volume":"52","author":"J. Wikstr\u00f6m","year":"1975","unstructured":"Wikstr\u00f6m, J.: The epidemiology of optic neuritis in Finland. Acta neurol. scand. 52, 196?206 (1975c)","journal-title":"Acta neurol. scand."},{"key":"CR38","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1111\/j.1600-0404.1975.tb01362.x","volume":"51","author":"J. Wikstr\u00f6m","year":"1975","unstructured":"Wikstr\u00f6m, J., Palo, J.: Studies on the clustering of multiple sclerosis in Finland. I: comparison between the domiciles and places of birth in selected subpopulations. Acta neurol. scand. 51, 85?98 (1975)","journal-title":"Acta neurol. scand."},{"key":"CR39","doi-asserted-by":"crossref","unstructured":"Wikstr\u00f6m, J., Westermarck, T., Palo, J.: Selenium, vitamin E and copper in multiple sclerosis. Acta neurol. scand. (in press)","DOI":"10.1111\/j.1600-0404.1976.tb04806.x"}],"container-title":["Journal of Neurology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF00313269.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/BF00313269\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF00313269","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,4,3]],"date-time":"2019-04-03T19:07:57Z","timestamp":1554318477000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/BF00313269"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1976]]},"references-count":39,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1976]]}},"alternative-id":["BF00313269"],"URL":"https:\/\/doi.org\/10.1007\/bf00313269","relation":{},"ISSN":["0340-5354","1432-1459"],"issn-type":[{"value":"0340-5354","type":"print"},{"value":"1432-1459","type":"electronic"}],"subject":[],"published":{"date-parts":[[1976]]}}}