{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T14:08:11Z","timestamp":1791036491386,"version":"4.1.0"},"reference-count":13,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[1991,1,1]],"date-time":"1991-01-01T00:00:00Z","timestamp":662688000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Eur J Clin Pharmacol"],"published-print":{"date-parts":[[1991,1]]},"DOI":"10.1007\/bf00315138","type":"journal-article","created":{"date-parts":[[2004,10,19]],"date-time":"2004-10-19T11:26:54Z","timestamp":1098185214000},"page":"49-52","source":"Crossref","is-referenced-by-count":48,"title":["Disposition of oral quinine in acute falciparum malaria"],"prefix":"10.1007","volume":"40","author":[{"given":"W.","family":"Supanaranond","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T. M. E.","family":"Davis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Pukrittayakamee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K.","family":"Silamut","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Karbwang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.","family":"Molunto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.","family":"Chanond","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N. J.","family":"White","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"CR1","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1002\/cpt196910185","volume":"10","author":"MH Brooks","year":"1969","unstructured":"Brooks MH, Malloy JP, Bartelloni P, Sheehy TW, Barry KG (1969) Quinine pyrimethamine and sulphorthodimethoxine. Clinical response, plasma levels and urinary excretion during the initial attack of naturally acquired falciparum malaria. Clin Pharmacol Ther 10: 85?91","journal-title":"Clin Pharmacol Ther"},{"key":"CR2","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1016\/S0378-4347(00)84807-0","volume":"278","author":"M Edstein","year":"1983","unstructured":"Edstein M, Stace J, Shann F (1983) Quantification of quinine in human serum by high performance liquid chromatography. J Chromatogr 278: 445?451","journal-title":"J Chromatogr"},{"key":"CR3","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1016\/0035-9203(76)90064-X","volume":"70","author":"JC Garnham","year":"1976","unstructured":"Garnham JC, Raymond D, Shotton E, Turner P (1976) The bioavailability of quinine. J Trop Med Hyg 70: 264?269","journal-title":"J Trop Med Hyg"},{"key":"CR4","unstructured":"Hall AP, Hanchalay S, Doberstyn EB, Bumnetphund S (1975) Quinine dosage and serum levels in falciparum malaria. SEATO Annual Progress Report of the Research Laboratories, Bangkok, pp240?250"},{"key":"CR5","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1111\/j.1365-2125.1988.tb03299.x","volume":"25","author":"A Jamaludin","year":"1988","unstructured":"Jamaludin A, Mohamad M, Navaratnam V, Selliah K, Tan SC, Wernsdorfer WH, Yuen KH (1988) Relative bioavailability of the hydrochloride, sulphate and ethylcarbonate salts of quinine. Br J Clin Pharmacol 25: 261?263","journal-title":"Br J Clin Pharmacol"},{"key":"CR6","first-page":"55","volume":"20","author":"J Karbwang","year":"1989","unstructured":"Karbwang J, Molunto P, Na Bangchang K, Bunnag D (1989) Determination of quinine and quinidine in biological fluids by high performance liquid chromatography. Southeast Asian J Trop Med Public Health 20: 55?60","journal-title":"Southeast Asian J Trop Med Public Health"},{"key":"CR7","doi-asserted-by":"crossref","first-page":"506","DOI":"10.1016\/S0022-3476(85)80692-2","volume":"106","author":"F Shann","year":"1985","unstructured":"Shann F, Stace J, Edstein M (1985) Pharmacokinetics of quinine in children. J Pediatr 106: 506?510","journal-title":"J Pediatr"},{"key":"CR8","doi-asserted-by":"crossref","first-page":"681","DOI":"10.4269\/ajtmh.1985.34.681","volume":"34","author":"K Silamut","year":"1985","unstructured":"Silamut K, White NJ, Looareesuwan S, Warrell DA (1985) Binding of quinine to plasma proteins in falciparum malaria. Am J Trop Med Hyg 34: 681?686","journal-title":"Am J Trop Med Hyg"},{"key":"CR9","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1172\/JCI101977","volume":"27","author":"JV Taggart","year":"1948","unstructured":"Taggart JV, Earle DP, Berliner RW et al. (1948) Studies on the chemotherapy of the human malarias II. The physiological disposition and antimalarial activity of the cinchona alkaloids. J Clin Invest 27: 80?86","journal-title":"J Clin Invest"},{"key":"CR10","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1002\/cpt1976194459","volume":"19","author":"GM Trenholme","year":"1976","unstructured":"Trenholme GM, Williams RL, Rieckman KH, Frischer H, Carson PE (1976) Quinine disposition during malaria and during induced fever. Clin Pharmacol Ther 19: 459?467","journal-title":"Clin Pharmacol Ther"},{"key":"CR11","first-page":"65","volume":"55","author":"NJ White","year":"1987","unstructured":"White NJ (1987) The pharmacokinetics of quinine and quinidine in malaria. Acta Leidensia 55: 65?76","journal-title":"Acta Leidensia"},{"key":"CR12","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/BF01061409","volume":"34","author":"NJ White","year":"1988","unstructured":"White NJ (1988) Drug treatment and prevention of malaria. Eur J Clin Pharmacol 34: 1?14","journal-title":"Eur J Clin Pharmacol"},{"key":"CR13","doi-asserted-by":"crossref","first-page":"564","DOI":"10.1016\/0002-9343(82)90337-0","volume":"73","author":"NJ White","year":"1982","unstructured":"White NJ, Looareesuwan S, Warrell DA, Warrell MJ, Bunnag D, Harinasuta T (1982) Quinine pharmacokinetics and toxicity in cerebral and uncomplicated falciparum malaria. Am J Med 73: 564?672","journal-title":"Am J Med"}],"container-title":["European Journal of Clinical Pharmacology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF00315138.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/BF00315138\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF00315138","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,4,3]],"date-time":"2019-04-03T15:08:46Z","timestamp":1554304126000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/BF00315138"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1991,1]]},"references-count":13,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1991,1]]}},"alternative-id":["BF00315138"],"URL":"https:\/\/doi.org\/10.1007\/bf00315138","relation":{},"ISSN":["0031-6970","1432-1041"],"issn-type":[{"value":"0031-6970","type":"print"},{"value":"1432-1041","type":"electronic"}],"subject":[],"published":{"date-parts":[[1991,1]]}}}