{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T09:32:08Z","timestamp":1790415128266,"version":"4.1.0"},"reference-count":27,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[1988,4,1]],"date-time":"1988-04-01T00:00:00Z","timestamp":575856000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arch Toxicol"],"published-print":{"date-parts":[[1988,4]]},"DOI":"10.1007\/bf00334616","type":"journal-article","created":{"date-parts":[[2004,10,26]],"date-time":"2004-10-26T09:56:25Z","timestamp":1098784585000},"page":"359-365","source":"Crossref","is-referenced-by-count":19,"title":["Nephrotoxicity of butylated hydroxytoluene in phenobarbital-pretreated male rats"],"prefix":"10.1007","volume":"61","author":[{"given":"Yoshio","family":"Nakagawa","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kiniaki","family":"Tayama","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"CR1","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1016\/0003-2697(76)90527-3","volume":"72","author":"M Bradford","year":"1976","unstructured":"Bradford M (1976) A rapid and sensitive method form the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72: 248?254","journal-title":"Anal Biochem"},{"key":"CR2","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1152\/ajplegacy.1950.161.1.181","volume":"161","author":"RJ Cross","year":"1950","unstructured":"Cross RJ, Taggart VJ (1950) Renal tubular transport: Accumulation of p-aminohippurate by rabbit kidney slices. Am J Physiol 161: 181?190","journal-title":"Am J Physiol"},{"key":"CR3","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1016\/S0015-6264(65)80128-6","volume":"3","author":"JW Daniel","year":"1965","unstructured":"Daniel JW, Gage JC (1965) The absorption and excretion of butylated hydroxytoluene (BHT) in the rat. Food Cosmet Toxicol 3: 405?415","journal-title":"Food Cosmet Toxicol"},{"key":"CR4","doi-asserted-by":"crossref","first-page":"783","DOI":"10.1042\/bj1060783","volume":"106","author":"JW Daniel","year":"1968","unstructured":"Daniel JW, Gage JC, Jones DI (1968) The metabolism of 3,5-ditert-butyl-4-hydroxytoluene in the rat and in the man. Biochem J 106: 783?790","journal-title":"Biochem J"},{"key":"CR5","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1136\/jcp.13.2.156","volume":"13","author":"JK Fawcett","year":"1960","unstructured":"Fawcett JK, Scott JE (1960) A rapid and precise method for the determination of urea. J Clin Pathol 13: 156?159","journal-title":"J Clin Pathol"},{"key":"CR6","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/0015-6264(80)90005-X","volume":"18","author":"SM Ford","year":"1980","unstructured":"Ford SM, Hook JB, Bond JT (1980) The effects of butylated hydroxyanisole and butylated hydroxytoluene on renal function in the rat. II Effects on organic acid and base transport. Food Cosmet Toxicol 18: 21?26","journal-title":"Food Cosmet Toxicol"},{"key":"CR7","first-page":"259","volume-title":"Ann Rev Pharmacol Toxicol 26","author":"TE Gram","year":"1986","unstructured":"Gram TE, Okine LK, Gram RA (1986) The metabolism of xenobiotics by certain extrahepatic organs and its relation to toxicity. In: George R, Okun R, Cho AK (eds) Ann Rev Pharmacol Toxicol 26. Annual Reviews Inc, California, pp 259?291"},{"key":"CR8","doi-asserted-by":"crossref","first-page":"1180","DOI":"10.1093\/clinchem\/27.7.1180","volume":"27","author":"E Horak","year":"1981","unstructured":"Horak E, Hopfer SM, Sunderman FW (1981) Spectrophotometric assay for urinary N-acetyl-?-d-glucosaminidase activity. Clin Chem 27: 1180?1185","journal-title":"Clin Chem"},{"key":"CR9","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1172\/JCI103055","volume":"34","author":"A Karmen","year":"1955","unstructured":"Karmen A (1955) A note on the spectrophotometric assay of glutamic-oxalacetic transaminase in human blood serum. J Clin Invest 34: 131?133","journal-title":"J Clin Invest"},{"key":"CR10","first-page":"67","volume":"19","author":"IA Karplyuk","year":"1960","unstructured":"Karplyuk IA (1960) Elementary raw fats containing phenolic antioxidants. An elevation from the point of view of hygiene. Vopr Pitaniya 19: 67","journal-title":"Vopr Pitaniya"},{"key":"CR11","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1136\/jcp.7.4.322","volume":"7","author":"PPN Kind","year":"1954","unstructured":"Kind PPN, King EJ (1954) Estimation plasma phosphatase by determination of hydrolyzed phenol with aminoantipyrine. J Clin Path 7: 322?326","journal-title":"J Clin Path"},{"key":"CR12","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1111\/j.2042-7158.1967.tb09564.x","volume":"19","author":"LG Ladomery","year":"1967","unstructured":"Ladomery LG, Ryan AJ, Wright SE (1967) The excretion of (14C) butylated hydroxytoluene in the rat. J Pharm Pharmacol 19: 383?387","journal-title":"J Pharm Pharmacol"},{"key":"CR13","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1007\/978-3-642-66896-8_77","volume":"1","author":"O Meyer","year":"1978","unstructured":"Meyer O, Blom L, Olsen P (1978) Influence of diet and strain of rat on kidney damage observed in toxicity studies. Arch Toxicol suppl 1: 355?358","journal-title":"Arch Toxicol suppl"},{"key":"CR14","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1016\/0041-008X(87)90094-9","volume":"87","author":"T Mizutani","year":"1987","unstructured":"Mizutani T, Nomura H, Nakanishi K, Fujita S (1987) Hepatotoxicity of butylated hydroxytoluene and its analogs in mice depleted of hepatic glutathione. Toxicol Appl Pharmacol 87: 166?176","journal-title":"Toxicol Appl Pharmacol"},{"key":"CR15","doi-asserted-by":"crossref","first-page":"442","DOI":"10.1248\/cpb.27.442","volume":"27","author":"Y Nakagawa","year":"1979","unstructured":"Nakagawa Y, Hiraga K, Suga T (1979a) Biological fate of butylated hydroxytoluene (BHT); binding in vivo of BHT to macromolecules of rat liver. Chem Pharm Bull 27: 442?446","journal-title":"Chem Pharm Bull"},{"key":"CR16","doi-asserted-by":"crossref","first-page":"480","DOI":"10.1248\/cpb.27.480","volume":"27","author":"Y Nakagawa","year":"1979","unstructured":"Nakagawa Y, Hiraga K, Suga T (1979b) Biological fate of butylated hydroxytoluene (BHT); binding in vitro of BHT to liver microsomes. Chem Pharm Bull 27: 480?485","journal-title":"Chem Pharm Bull"},{"key":"CR17","doi-asserted-by":"crossref","first-page":"887","DOI":"10.1016\/S0006-2952(81)80012-3","volume":"30","author":"Y Nakagawa","year":"1981","unstructured":"Nakagawa Y, Hiraga K, Suga T (1981) Biological fate of butylated hydroxytoluene (BHT); binding of BHT metabolites to cysteine in vitro. Biochem Pharmacol 30: 887?890","journal-title":"Biochem Pharmacol"},{"key":"CR18","doi-asserted-by":"crossref","first-page":"1417","DOI":"10.1016\/0006-2952(83)90456-2","volume":"32","author":"Y Nakagawa","year":"1983","unstructured":"Nakagawa Y, Hiraga K, Suga T (1983) On the mechanism of covalent binding of butylated hydroxytoluene to microsomal protein. Biochem Pharmacol 32: 1417?1421","journal-title":"Biochem Pharmacol"},{"key":"CR19","doi-asserted-by":"crossref","first-page":"2669","DOI":"10.1016\/0006-2952(84)90643-9","volume":"33","author":"Y Nakagawa","year":"1984","unstructured":"Nakagawa Y, Tayama K, Nakao T, Hiraga K (1984) On the mechanism of butylated hydroxytoluene-induced hepatic toxicity in rats. Biochem Pharmacol 33: 2669?2674","journal-title":"Biochem Pharmacol"},{"key":"CR20","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/0378-4274(85)90144-4","volume":"24","author":"Y Nakagawa","year":"1985","unstructured":"Nakagawa Y, Tayama K, Nakao T, Hiraga T (1985) Effect of cobaltous chloride on butylated hydroxytoluene-induced hepatic necrosis in rats. Toxicol Lett 24: 85?89","journal-title":"Toxicol Lett"},{"key":"CR21","doi-asserted-by":"crossref","first-page":"336","DOI":"10.1016\/0041-008X(82)90017-5","volume":"65","author":"JF Newton","year":"1982","unstructured":"Newton JF, Kuo CH, Gembory NW, Mudge GH, Hook JB (1982) Nephrotoxicity of p-aminophenol, a metabolite of acetaminophen, in the Fischer 344 rat. Toxicol Appl Pharmacol 65: 336?344","journal-title":"Toxicol Appl Pharmacol"},{"key":"CR22","doi-asserted-by":"crossref","first-page":"821","DOI":"10.1007\/BF01923152","volume":"28","author":"EE Ohnhaus","year":"1972","unstructured":"Ohnhaus EE (1972) Urinary excretion of chlorothiazide in rats before and after phenobarbitone administration. Experientia 28: 821?822","journal-title":"Experientia"},{"key":"CR23","first-page":"141","volume":"52","author":"EE Ohnhaus","year":"1974","unstructured":"Ohnhaus EE, Siegl H (1974) Changes in renal function following chronic phenobarbitone administration. Br J Pharmacol 52: 141","journal-title":"Br J Pharmacol"},{"key":"CR24","doi-asserted-by":"crossref","first-page":"1131","DOI":"10.1016\/0278-6915(86)90299-1","volume":"24","author":"CJ Powell","year":"1986","unstructured":"Powell CJ, Connelly JC, Jones SM, Grasso P, Bridges JW (1986) Hepatic responses to the administration of high doses of BHT to the rat: their relevance to hepatocarcinogenicity. Food Chem Toxicol 24: 1131?1143","journal-title":"Food Chem Toxicol"},{"key":"CR25","doi-asserted-by":"crossref","first-page":"388","DOI":"10.1172\/JCI101618","volume":"25","author":"HW Smith","year":"1945","unstructured":"Smith HW, Finkelstein N, Aliminosa L, Crawford B, Graber M (1945) The renal clearance of substituted hippuric acid derivatives and other aromatic acids in dog and man. J Clin Invest 25: 388?404","journal-title":"J Clin Invest"},{"key":"CR26","unstructured":"WHO Technical Report Series (1987) Evaluation of certain food additives and contaminants. Thirtieth Report of the Joint FAD\/WHO Expert Committee on Food Additives, Geneva, pp 12?52"},{"key":"CR27","doi-asserted-by":"crossref","first-page":"210","DOI":"10.3181\/00379727-90-21985","volume":"90","author":"F Wroblewski","year":"1955","unstructured":"Wroblewski F, LaDue JS (1955) Lactic dehydrogenase activity in blood. Proc Soc Exp Biol Med 90: 210?213","journal-title":"Proc Soc Exp Biol Med"}],"container-title":["Archives of Toxicology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF00334616.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/BF00334616\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF00334616","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,4,3]],"date-time":"2020-04-03T13:28:11Z","timestamp":1585920491000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/BF00334616"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1988,4]]},"references-count":27,"journal-issue":{"issue":"5","published-print":{"date-parts":[[1988,4]]}},"alternative-id":["BF00334616"],"URL":"https:\/\/doi.org\/10.1007\/bf00334616","relation":{},"ISSN":["0340-5761","1432-0738"],"issn-type":[{"value":"0340-5761","type":"print"},{"value":"1432-0738","type":"electronic"}],"subject":[],"published":{"date-parts":[[1988,4]]}}}