{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,12,21]],"date-time":"2024-12-21T07:10:01Z","timestamp":1734765001000,"version":"3.32.0"},"reference-count":33,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[1994,1,1]],"date-time":"1994-01-01T00:00:00Z","timestamp":757382400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["World j. surg."],"published-print":{"date-parts":[[1994,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>A solid gastric emptying study was conducted on 46 patients more than 1 year after highly selective vagotomy (HSV) and additional procedures for obstructing duodenal ulcer and on 21 patients after HSV alone for uncomplicated duodenal ulcer. The additional procedures included dilatation (<jats:italic>n<\/jats:italic>=14; HSV+D group), Holle pyloroplasty (<jats:italic>n<\/jats:italic>=14; HSV+P group), and Jaboulay gastroduodenostomy (<jats:italic>n<\/jats:italic>=18; HSV+GD group). The test meal consisted of two eggs labeled with<jats:sup>99m<\/jats:sup>Tc sulfur colloid, two slices of white bread toast, and 300\u00a0ml of organge juice (total 322 kcal). Gastric emptying curves and emptying parameters (t<jats:sup>1\/2<\/jats:sup>, half emptying time; lag phase, T<jats:sub>LAG<\/jats:sub>; emptying rate, k; and \u03b2 value) were compared with those of 17 healthy volunteers, the normal control group. The patients after HSV alone had an almost normal gastric emptying. The HSV+D group showed a significant delay from minute 45 to the end of the emptying curve, corresponding to a longer t<jats:sup>1\/2<\/jats:sup>(<jats:italic>p<\/jats:italic>=0.02), and a slower emptying rate (<jats:italic>p<\/jats:italic>=0.029). The HSV+P group approached a nearly normal emptying curve, corresponding to an insignificant difference in emptying parameters. The HSV+GD group had significantly faster emptying from minute 15 to the end of the emptying curve, corresponding to a faster t<jats:sup>1\/2<\/jats:sup>(<jats:italic>p<\/jats:italic>=0.0005), a shorter lag phase (<jats:italic>p<\/jats:italic>=0.027), and a faster emptying rate (<jats:italic>p<\/jats:italic>=0.021). Recurrent ulcerations were noted in one patient (4.8%) of the HSV alone group, five (35.7%) of the HSV+D group, one (7.1%) of the HSV+P group, and one (5.6%) of the HSV+GD group. This study indicates that HSV plus dilatation is not an adequate operation because of the high incidence of delayed gastric emptying and recurrence. Drainage is necessary for prevention of post\u2010operative delayed gastric emptying after HSV treatment for an obstructing duodenal ulcer. To achieve nearly normal gastric emptying, Holle pyloroplasty is the first choice for drainage. Because of a rare dumping syndrome in our patients, Jaboulay gastroduodenostomy is another choice, if the stenosis cannot be managed easily by Holle pyloroplasty.<\/jats:p>","DOI":"10.1007\/bf00348203","type":"journal-article","created":{"date-parts":[[2004,12,10]],"date-time":"2004-12-10T07:37:32Z","timestamp":1102664252000},"page":"131-137","source":"Crossref","is-referenced-by-count":4,"title":["Effects of highly selective vagotomy and additional procedures on gastric emptying in patients with obstructing duodenal ulcer"],"prefix":"10.1002","volume":"18","author":[{"given":"Chia\u2010Siu","family":"Wang","sequence":"first","affiliation":[{"name":"Department of Surgery Chang Gung Medical College 199, Tung Hwa North Road Taipei Taiwan Republic of China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kai\u2010Yuan","family":"Tzen","sequence":"additional","affiliation":[{"name":"Department of Nuclear Medicine Chang Gung Medical College 199, Tung Hwa North Road Taipei Taiwan Republic of China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pang\u2010Chi","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology Chang Gung Medical College 199, Tung Hwa North Road Taipei Taiwan Republic of China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Miin\u2010Fu","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Surgery Chang Gung Medical College 199, Tung Hwa North Road Taipei Taiwan Republic of China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[1994,1]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000658-198902000-00001"},{"key":"e_1_2_1_3_1","first-page":"101","article-title":"Proximal gastric vagotomy [symposium]","volume":"25","author":"Herrington J.L.","year":"1984","journal-title":"Contemp. 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