{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T06:27:13Z","timestamp":1790922433124,"version":"4.1.0"},"reference-count":36,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[1987,1,1]],"date-time":"1987-01-01T00:00:00Z","timestamp":536457600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int. Arch Occup Environ Heath"],"published-print":{"date-parts":[[1987,1]]},"DOI":"10.1007\/bf00377675","type":"journal-article","created":{"date-parts":[[2004,11,6]],"date-time":"2004-11-06T08:29:41Z","timestamp":1099729781000},"page":"21-30","source":"Crossref","is-referenced-by-count":73,"title":["Mechanism for bone disease found in inhabitants environmentally exposed to cadmium: decreased serum 1?, 25-dihydroxyvitamin D level"],"prefix":"10.1007","volume":"59","author":[{"given":"K\ufffdji","family":"Nogawa","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ikiko","family":"Tsuritani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ternhiko","family":"Kido","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ryumon","family":"Honda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuichi","family":"Yamada","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masao","family":"Ishizaki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"CR1","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1016\/S0006-291X(80)80222-1","volume":"94","author":"T Akiba","year":"1980","unstructured":"Akiba T, Endou H, Koseki C, Sakai F (1980) Localization of 25-hydroxyvitamin D3-1?-hydroxylase activity in the mammalian kidney. Biochem Biophys Res Commun 94:313?318","journal-title":"Biochem Biophys Res Commun"},{"key":"CR2","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1016\/0041-008X(81)90350-1","volume":"61","author":"M Ando","year":"1981","unstructured":"Ando M, Shimizu M, Sayato Y, Tanimura A, Tobe M (1981) The inhibition of vitamin D-stimulated intestinal calcium transport in rats after continuous oral administration of cadmium. Toxicol Appl Pharmacol 61:297?301","journal-title":"Toxicol Appl Pharmacol"},{"key":"CR3","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1001\/archpedi.1980.02130140014005","volume":"134","author":"TW Chesney","year":"1980","unstructured":"Chesney TW, Rosen JF, Hamstra AJ, Deluca HF (1980) Serum 1,25-dihydroxyvitamin D levels in normal children and in vitamin D disorders. Am J Dis Child 134:135?139","journal-title":"Am J Dis Child"},{"key":"CR4","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1016\/0003-9861(76)90161-2","volume":"176","author":"JA Eisman","year":"1976","unstructured":"Eisman JA, Hamstra AJ, Kream BE, Deluca HF (1976) A sensitive, precise and convenient method for determination of 1,25-dihydroxyvitamin D in human plasma. Arch Biochem Biophys 176:235?243","journal-title":"Arch Biochem Biophys"},{"key":"CR5","first-page":"251","volume":"8","author":"SL Feldman","year":"1973","unstructured":"Feldman SL, Cousins RJ (1973) Influence of cadmium on the metabolism of 25-hydroxycholecalciferol in chicks. Nutr Rep Int 8:251?259","journal-title":"Nutr Rep Int"},{"key":"CR6","volume-title":"Cadmium in the environment","author":"L Friberg","year":"1974","unstructured":"Friberg L, Piscator M, Nordberg GF, Kjellstr\u00f6m T (1974) Cadmium in the environment, 2nd ed. CRC Press, Cleveland, Ohio","edition":"2nd ed."},{"key":"CR7","doi-asserted-by":"crossref","first-page":"386","DOI":"10.1016\/0013-9351(80)90150-4","volume":"22","author":"CS Fullmer","year":"1980","unstructured":"Fullmer CS, Oku T, Wasserman RH (1980) Effect of cadmium administration on intestinal absorption and vitamin D-dependent calcium-binding protein. Environ Res 22:386?399","journal-title":"Environ Res"},{"key":"CR8","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1016\/0041-008X(82)90109-0","volume":"62","author":"H Iguchi","year":"1982","unstructured":"Iguchi H, Sano S (1982) Effect of cadmium on the collagen metabolism of rat. Toxicol Appl Pharmacol 62:126?136","journal-title":"Toxicol Appl Pharmacol"},{"key":"CR9","first-page":"271","volume":"23","author":"A Ishizaki","year":"1968","unstructured":"Ishizaki A, Fukushima M (1968) Studies on itai-itai disease (review). Jpn J Hyg 23:271?285 (in Japanese)","journal-title":"Jpn J Hyg"},{"key":"CR10","first-page":"309","volume":"83","author":"K Kajikawa","year":"1974","unstructured":"Kajikawa K, Kitagawa M, Nakanishi I, Ueshima H, Katsuda S, Kuroda K (1974) A pathological study of itai-itai disease. J Juzen Med Soc 83:309?347 (in Japanese)","journal-title":"J Juzen Med Soc"},{"key":"CR11","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1159\/000181202","volume":"20","author":"J Kawamura","year":"1978","unstructured":"Kawamura J, Yoshida O, Nishio K, Itokawa Y (1978) Disturbances in kidney functions and calcium and phosphate metabolism in cadmium-poisoned rats. Nephron 20:101?110","journal-title":"Nephron"},{"key":"CR12","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1016\/0003-9861(74)90172-6","volume":"165","author":"M Kimura","year":"1974","unstructured":"Kimura M, Otaki N, Yoshiki S, Suzuki M, Horiuchi N, Suda T (1974) The isolation of metallothionein and its protective role in cadmium poisoning. Arch Biochem Biophys 165:340?348","journal-title":"Arch Biochem Biophys"},{"key":"CR13","first-page":"495","volume":"7","author":"SE Larsson","year":"1971","unstructured":"Larsson SE, Piscator M (1971) Effect of cadmium on skeletal tissue in normal and calcium-deficient rats. Isr J Med Sci 7:495?497","journal-title":"Isr J Med Sci"},{"key":"CR14","first-page":"559","volume":"30","author":"R Lorentzon","year":"1977","unstructured":"Lorentzon R, Larsson SE (1977) Vitamin D metabolism in adult rats at low and normal calcium intake and the effect of cadmium exposure. Clin Sci Mol Med 30:559?562","journal-title":"Clin Sci Mol Med"},{"key":"CR15","first-page":"287","volume":"42","author":"T Maehara","year":"1978","unstructured":"Maehara T (1978) Studies on the calcium metabolism of rat bone after long-term administration of heavy metal (cadmium). J Japan Orthopaedic Assoc 42:287?300 (in Japanese)","journal-title":"J Japan Orthopaedic Assoc"},{"key":"CR16","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1016\/0300-483X(75)90100-6","volume":"4","author":"Z Merali","year":"1975","unstructured":"Merali Z, Singhal RL (1975) Influence of chronic exposure to cadmium on hepatic and renal cyclic AMP-protein kinase system. Toxicology 4:207?214","journal-title":"Toxicology"},{"key":"CR17","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/0378-4274(80)90181-2","volume":"6","author":"T Miyahara","year":"1980","unstructured":"Miyahara T, Komurasaki T, Kozuka H (1980) Inhibitory effect of cadmium on collagenous peptide synthesis of embryonic chick bone in tissue culture. Toxicol Lett 6:137?139","journal-title":"Toxicol Lett"},{"key":"CR18","doi-asserted-by":"crossref","first-page":"761","DOI":"10.1265\/jjh.35.761","volume":"35","author":"A Mukawa","year":"1980","unstructured":"Mukawa A, Nogawa K, Hagino N (1980) Bone biopsy performed on women living in the cadmium-polluted Jinzu River basin. Jpn J Hyg 35:761?773 (in Japanese)","journal-title":"Jpn J Hyg"},{"key":"CR19","first-page":"1","volume":"56","author":"S Nakagawa","year":"1960","unstructured":"Nakagawa S (1960) A study of osteomalacia in Toyama Prefecture (so-called itai-itai disease). J Radiol Phys Ther Univ Kanazawa 56:1?51 (in Japanese)","journal-title":"J Radiol Phys Ther Univ Kanazawa"},{"key":"CR20","first-page":"595","volume":"55","author":"Y Nishi","year":"1981","unstructured":"Nishi Y, Nanjo M (1981) Method for assay of vitamin D; 3. Multiple assay of vitamin D and its metabolites. Vitamins (Japan) 55:595?605 (in Japanese)","journal-title":"Vitamins (Japan)"},{"key":"CR21","first-page":"1","volume-title":"Cadmium in the environment","author":"K Nogawa","year":"1981","unstructured":"Nogawa K (1981) Itai-itai disease and follow-up studies. In: Nriagu JO (ed) Cadmium in the environment. John Wiley & Son Inc, New York, pp 1?37"},{"key":"CR22","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1016\/0378-4274(83)90236-9","volume":"17","author":"K Nogawa","year":"1983","unstructured":"Nogawa K, Yamada Y, Honda R, Ishizaki M, Tsuritani I, Kawano S, Kato T (1983) The relationship between itai-itai disease among inhabitants of the Jinzu River basin and cadmium in rice. Toxicol Lett 17:263?266","journal-title":"Toxicol Lett"},{"key":"CR23","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1007\/BF00379048","volume":"54","author":"K Nogawa","year":"1984","unstructured":"Nogawa K, Kobayashi E, Yamada Y, Honda R, Kido T, Tsuritani I, Ishizaki M (1984) Parathyroid hormone concentration in the serum of people with cadmium-induced renal damage. Int Arch Occup Environ Health 54:187?193","journal-title":"Int Arch Occup Environ Health"},{"key":"CR24","first-page":"139","volume-title":"Cadmium-induced osteopathy","author":"H Saito","year":"1979","unstructured":"Saito H, Shitomi K (1979) Chronic cadmium poisoning, Fanconi syndrome and osteomalacia. In: Cadmium-induced osteopathy. Shigematsu I, Nomiyama K (eds) Tokyo: Japan Public Health Association, pp 139?143"},{"key":"CR25","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1042\/bj1820055","volume":"182","author":"RM Shepard","year":"1979","unstructured":"Shepard RM, Horst RL, Hamstra AJ (1979) Determination of vitamin D and its metabolites in plasma from normal and anephric man. Biochem J 182:55?69","journal-title":"Biochem J"},{"key":"CR26","first-page":"173","volume":"52","author":"F Shimura","year":"1978","unstructured":"Shimura F, Tamura M (1978) Application of normal hen intestinal cytosol for the radioreceptor assay of serum 1?,25-dihydroxycholecalciferol concentration. Vitamins (Japan) 52:173?181 (in Japanese)","journal-title":"Vitamins (Japan)"},{"key":"CR27","first-page":"67","volume":"50","author":"R Suda","year":"1984","unstructured":"Suda R, Shiina Y, Abe E (1984) The influence of nutritional factors and cadmium exposure on monkeys; 5. Plasma concentrations of vitamin D metabolites. Kankyo Hoken Report No 50:67?72 (in Japanese)","journal-title":"Kankyo Hoken Report"},{"key":"CR28","volume-title":"Vitamin D","author":"T Suda","year":"1982","unstructured":"Suda T, Ogata E, Ogura Y, Nishii Y (1982) Vitamin D. Tokyo, Kodansha (in Japanese)"},{"key":"CR29","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1265\/jjh.28.511","volume":"28","author":"Ch Sugawara","year":"1974","unstructured":"Sugawara Ch, Sugawara N (1974) Cadmium toxicity for rat intestine specially on the absorption of calcium and phosphorus. Jpn J Hyg 28:511?516 (in Japanese)","journal-title":"Jpn J Hyg"},{"key":"CR30","first-page":"63","volume":"3","author":"Y Sugimura","year":"1985","unstructured":"Sugimura Y, Higaki M (1985) Measurement of 1?,25-dihydroxyvitamin D in serum of healthy people using Amersham assay system. J Bone and Mineral Metab (Proceedings of the Third Conference of Japanese Society of Bone Metabolism Research) 3:63 (in Japanese)","journal-title":"J Bone and Mineral Metab (Proceedings of the Third Conference of Japanese Society of Bone Metabolism Research)"},{"key":"CR31","first-page":"124","volume-title":"Cadmium-induced osteopathy","author":"S Takebayashi","year":"1979","unstructured":"Takebayashi S (1979) First autopsy case, suspicious of cadmium intoxication, from the cadmium-polluted area in Tsushima, Nagasaki Prefecture. In: Shigematsu I, Nomiyama K (eds) Cadmium-induced osteopathy. Japan Public Health Association, Tokyo, pp 124?138"},{"key":"CR32","first-page":"207","volume":"49","author":"S Takebayashi","year":"1983","unstructured":"Takebayashi S (1983) Second case of osteomalacia found in women requiring observation in a cadmium-polluted area in Tsushima. Clinical and pathological findings. Kankyo Hoken Report No 49:207?211 (in Japanese)","journal-title":"Kankyo Hoken Report"},{"key":"CR33","first-page":"238","volume":"50","author":"S Takebayashi","year":"1984","unstructured":"Takebayashi S (1984) Third case of osteomalacia found in women requiring observation in a cadmium-polluted area in Tsushima. Clinical and pathological findings. Kankyo Hoken Report No 50:238?241 (in Japanese)","journal-title":"Kankyo Hoken Report"},{"key":"CR34","first-page":"7","volume":"11","author":"Y Yamamoto","year":"1972","unstructured":"Yamamoto Y (1972) Present status of environmental cadmium pollution. Kankyo Hoken Report No 11:7?12 (in Japanese)","journal-title":"Kankyo Hoken Report"},{"key":"CR35","first-page":"117","volume":"4","author":"M Yoneda","year":"1983","unstructured":"Yoneda M Tomita A, Uchikawa A, Takatsuki K (1983) Basic and clinical studies on human parathyroid hormone using the homologous radioimmunoassay kit ?Eiken?. Clin Endocrinol 4:117?121 (in Japanese)","journal-title":"Clin Endocrinol"},{"key":"CR36","first-page":"41","volume":"41","author":"S Yumita","year":"1983","unstructured":"Yumita S, Son T, Miura R, Furukawa Y (1983) The fundamental and clinical studies on human parathyroid hormone radioimmunoassay kit. Clin Endocrinol 41:41?46 (in Japanese)","journal-title":"Clin Endocrinol"}],"container-title":["International Archives of Occupational and Environmental Health"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF00377675.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/BF00377675\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF00377675","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,4,8]],"date-time":"2019-04-08T21:47:45Z","timestamp":1554760065000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/BF00377675"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1987,1]]},"references-count":36,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1987,1]]}},"alternative-id":["BF00377675"],"URL":"https:\/\/doi.org\/10.1007\/bf00377675","relation":{},"ISSN":["0340-0131","1432-1246"],"issn-type":[{"value":"0340-0131","type":"print"},{"value":"1432-1246","type":"electronic"}],"subject":[],"published":{"date-parts":[[1987,1]]}}}