{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T22:29:14Z","timestamp":1785536954583,"version":"3.56.0"},"reference-count":34,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[1992,1,1]],"date-time":"1992-01-01T00:00:00Z","timestamp":694224000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diabetologia"],"published-print":{"date-parts":[[1992,1]]},"DOI":"10.1007\/bf00400848","type":"journal-article","created":{"date-parts":[[2004,11,9]],"date-time":"2004-11-09T18:06:20Z","timestamp":1100023580000},"page":"26-31","source":"Crossref","is-referenced-by-count":50,"title":["Human islet amyloid polypeptide at pharmacological levels inhibits insulin and phorbol ester-stimulated glucose transport in in vitro incubated human muscle strips"],"prefix":"10.1007","volume":"35","author":[{"given":"J. R.","family":"Zierath","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.","family":"Galuska","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"\ufffd.","family":"Engstr\ufffdm","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K. H.","family":"Johnson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Betsholtz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.","family":"Westermark","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H.","family":"Wallberg-Henriksson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"CR1","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1007\/BF01219652","volume":"15","author":"P Westermark","year":"1978","unstructured":"Westermark P, Wilander E (1978) The influence of amyloid deposits on the islet volume in maturity onset diabetes mellitus. Diabetologia 15: 417?421","journal-title":"Diabetologia"},{"key":"CR2","doi-asserted-by":"crossref","first-page":"3881","DOI":"10.1073\/pnas.84.11.3881","volume":"84","author":"P Westermark","year":"1987","unstructured":"Westermark P, Wernstedt C, Wilander E, Hayden DW, O'Brien TD, Johnson KH (1987) Amyloid fibrils in human insulinoma and islets of Langerhans of the diabetic cat are derived from a neuropeptide-like protein also present in normal islet cells. Proc Natl Acad Sci USA 84: 3881?3885","journal-title":"Proc Natl Acad Sci USA"},{"key":"CR3","doi-asserted-by":"crossref","first-page":"8628","DOI":"10.1073\/pnas.84.23.8628","volume":"84","author":"GJS Cooper","year":"1987","unstructured":"Cooper GJS, Willis AC, Clark A, Turner RC, Sim RB, Reid KBM (1987) Purification and characterization of a peptide from amyloid-rich pancreases of type 2 diabetic patients. Proc Natl Acad Sci USA 84: 8628?8632","journal-title":"Proc Natl Acad Sci USA"},{"key":"CR4","doi-asserted-by":"crossref","first-page":"7763","DOI":"10.1073\/pnas.85.20.7763","volume":"85","author":"GJS Cooper","year":"1988","unstructured":"Cooper GJS, Leighton B, Dimitriadis BD et al. (1988) Amylin found in amyloid deposits in human type 2 diabetes mellitus may be a hormone that regulates glycogen metabolism in skeletal muscle. Proc Natl Acad Sci USA 85: 7763?7766","journal-title":"Proc Natl Acad Sci USA"},{"key":"CR5","doi-asserted-by":"crossref","first-page":"632","DOI":"10.1038\/335632a0","volume":"335","author":"B Leighton","year":"1988","unstructured":"Leighton B, Cooper GJS (1988) Pancreatic amylin and calcitonin gene-related peptide cause resistance to insulin in skeletal muscle in vitro. Nature (Lond) 335: 632?635","journal-title":"Nature (Lond)"},{"key":"CR6","doi-asserted-by":"crossref","first-page":"260","DOI":"10.2337\/diab.39.2.260","volume":"39","author":"JM Molina","year":"1990","unstructured":"Molina JM, Cooper GJS, Leighton B, Olefsky JM (1990) Induction of insulin resistance in vivo by amylin and calcitonin gene-related peptide. Diabetes 39: 260?265","journal-title":"Diabetes"},{"key":"CR7","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1007\/BF00401051","volume":"33","author":"R Sowa","year":"1990","unstructured":"Sowa R, Sanke T, Hirayama J et al. (1990) Islet amyloid polypeptide amide causes peripheral insulin resistance in vivo in dogs. Diabetologia 33: 118?120","journal-title":"Diabetologia"},{"key":"CR8","first-page":"E457","volume":"259","author":"DA Young","year":"1990","unstructured":"Young DA, Deems RO, Deacon RW, McIntosh RH, Foley JE (1990) Effects of amylin on glucose metabolism and glycogenolysis in vivo and in vitro. Am J Physiol 259 (Endocrinol Metab 22): E457-E461","journal-title":"Am J Physiol"},{"key":"CR9","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1016\/0006-291X(90)90352-N","volume":"169","author":"JS Hothersall","year":"1990","unstructured":"Hothersall JS, Muirhead RP, Wimalawansa S (1990) The effect of amylin and calcitonin gene-related peptide on insulin-stimulated glucose transport in the diaphram. Biochem Biophys Res Comm 169: 451?454","journal-title":"Biochem Biophys Res Comm"},{"key":"CR10","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1042\/bj2690019","volume":"269","author":"B Leighton","year":"1990","unstructured":"Leighton B, Foot E (1990) The effects of amylin on carbohydrate metabolism in skeletal muscle in vitro and in vivo. Biochem J 269: 19?23","journal-title":"Biochem J"},{"key":"CR11","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1007\/BF00401050","volume":"33","author":"D Bretherton-Watt","year":"1990","unstructured":"Bretherton-Watt D, Gilbey SG, Ghatei MA, Beacham J, Bloom SR (1990) Failure to establish islet amyloid polypeptide (amylin) as a circulating beta cell inhibiting hormone in man. Diabetologia 33: 115?117","journal-title":"Diabetologia"},{"key":"CR12","doi-asserted-by":"crossref","first-page":"486","DOI":"10.1172\/JCI113622","volume":"82","author":"GL Dohm","year":"1988","unstructured":"Dohm GL, Tapscott EB, Pories WJ et al. (1988) An in vitro human muscle preparation suitable for metabolic studies. J Clin Invest 82: 486?494","journal-title":"J Clin Invest"},{"key":"CR13","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1515\/bchm2.1932.210.1-2.33","volume":"210","author":"HA Krebs","year":"1932","unstructured":"Krebs HA, Henseleit K (1932) Untersuchungen \u00fcber die Harnstoffbildung im Tierk\u00f6rper. Hoppe-Seyler's Z Physiol Chem 210: 33?66","journal-title":"Hoppe-Seyler's Z Physiol Chem"},{"key":"CR14","doi-asserted-by":"crossref","first-page":"7665","DOI":"10.1016\/S0021-9258(18)47618-1","volume":"262","author":"H Wallberg-Henriksson","year":"1987","unstructured":"Wallberg-Henriksson H, Zetan N, Henriksson J (1987) Reversibility of decreased insulin-stimulated glucose transport capacity in diabetic muscle with in vitro incubation. J Biol Chem 262: 7665?7671","journal-title":"J Biol Chem"},{"key":"CR15","doi-asserted-by":"crossref","first-page":"2149","DOI":"10.1021\/ja00897a025","volume":"85","author":"RB Merrifield","year":"1963","unstructured":"Merrifield RB (1963) Solid phase peptide synthesis. I. The synthesis of a tetrapeptide. J Am Chem Soc 85: 2149?2154","journal-title":"J Am Chem Soc"},{"key":"CR16","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1002\/mas.1280040403","volume":"4","author":"B Sundqvist","year":"1985","unstructured":"Sundqvist B, MacFarlane RD (1985) 252Cf-Plasma desorption mass spectrometry. Mass Spectrom Rev 4: 421?460","journal-title":"Mass Spectrom Rev"},{"key":"CR17","volume-title":"A flexible system of enzymatic analysis","author":"OH Lowry","year":"1972","unstructured":"Lowry OH, Passonneau JV (1972) A flexible system of enzymatic analysis. Academic Press, New York"},{"key":"CR18","doi-asserted-by":"crossref","first-page":"291","DOI":"10.3109\/00365517409082499","volume":"33","author":"R Keiding","year":"1974","unstructured":"Keiding R (1974) Recommended methods for the determination of four enzymes in blood. Scand J Clin Lab Invest 33: 291?306","journal-title":"Scand J Clin Lab Invest"},{"key":"CR19","first-page":"301","volume":"40","author":"Y Nishizuka","year":"1984","unstructured":"Nishizuka Y, Takai Y, Kishimoto A, Kikkawa U, Kaibuchi K (1984) Phospholipid turnover in hormone action. Rect Prog Horm Res 40: 301?345","journal-title":"Rect Prog Horm Res"},{"key":"CR20","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1111\/j.1748-1716.1991.tb09154.x","volume":"142","author":"K Andr\u00e9asson","year":"1991","unstructured":"Andr\u00e9asson K, Galuska D, Th\u00f6rne A, Sonnenfeld T, Wallberg-Henriksson H (1991) Decreased insulin-stimulated 3-0-methylglucose transport in in vitro incubated muscle strips from type II diabetic subjects. Acta Physiol Scan 142: 255?260","journal-title":"Acta Physiol Scan"},{"key":"CR21","doi-asserted-by":"crossref","first-page":"21536","DOI":"10.1016\/S0021-9258(20)88218-0","volume":"264","author":"EJ Henriksen","year":"1989","unstructured":"Henriksen EJ, Rodnick KJ, Holloszy JO (1989) Activation of glucose transport in skeletal muscle by phospholipase C and phorbol ester. J Biol Chem 264: 21536?21543","journal-title":"J Biol Chem"},{"key":"CR22","first-page":"1","volume":"564","author":"H Wallberg-Henriksson","year":"1987","unstructured":"Wallberg-Henriksson H (1987) Glucose transport into skeletal muscle: influence of contractile activity, insulin, catecholamines and diabetes mellitus. Acta Physiol Scan [Suppl] 564: 1?80","journal-title":"Acta Physiol Scan"},{"key":"CR23","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1042\/bj2250523","volume":"225","author":"G Werve Van de","year":"1985","unstructured":"Van de Werve G, Proietto J, Jeanrenaud B (1985) Tumour-promoting phorbol esters increase basal and inhibit insulin-stimulated lipogenesis in rat adipocytes without decreasing insulin binding. Biochem J 225: 523?527","journal-title":"Biochem J"},{"key":"CR24","doi-asserted-by":"crossref","first-page":"824","DOI":"10.1016\/0006-291X(85)90121-4","volume":"128","author":"D Kirsch","year":"1985","unstructured":"Kirsch D, Obermaier B, H\u00e4ring HU (1985) Phorbolesters enhance basal D-glucose transport but inhibit insulin stimulation of D-glucose transport and insulin binding in isolated rat adipocytes. Biochem Biophys Res Comm 128: 824?832","journal-title":"Biochem Biophys Res Comm"},{"key":"CR25","doi-asserted-by":"crossref","first-page":"2650","DOI":"10.1210\/endo-116-6-2650","volume":"116","author":"RV Farese","year":"1985","unstructured":"Farese RV, Standaert ML, Barnes DE, Davis JS, Pollet RJ (1985) Phorbol ester provokes insulin-like effects on glucose transport, amino acid uptake, and pyruvate dehydrogenase activity in BC3H-1 cultured myocytes. Endocrinology 116: 2650?2655","journal-title":"Endocrinology"},{"key":"CR26","doi-asserted-by":"crossref","first-page":"1759","DOI":"10.1210\/endo-118-5-1759","volume":"118","author":"G Cherqui","year":"1986","unstructured":"Cherqui G, Caron M, Wicek D, Lascols O, Capeau J, Picard J (1986) Insulin stimulation of glucose metabolism in rat adipocytes: possible implication of protein kinase C. Endocrinology 118: 1759?1769","journal-title":"Endocrinology"},{"key":"CR27","doi-asserted-by":"crossref","first-page":"752","DOI":"10.2337\/diab.39.6.752","volume":"39","author":"PC Butler","year":"1990","unstructured":"Butler PC, Chou J, Bradford Carter W et al. (1990) Effects of meal ingestion on plasma amylin concentration in NIDDM and nondiabetic humans. Diabetes 39: 752?756","journal-title":"Diabetes"},{"key":"CR28","doi-asserted-by":"crossref","first-page":"305","DOI":"10.2337\/diab.40.3.305","volume":"40","author":"DF Steiner","year":"1991","unstructured":"Steiner DF, Ohagi S, Nagamatsu S, Bell GI, Nishi M (1991) Is islet amyloid polypeptide a significant factor in pathogenesis or pathophysiology of diabetes? Diabetes 40: 305?309","journal-title":"Diabetes"},{"key":"CR29","doi-asserted-by":"crossref","first-page":"394","DOI":"10.1016\/0006-291X(89)91732-4","volume":"164","author":"M Nakazato","year":"1989","unstructured":"Nakazato M, Asai J, Kangawa K, Matsukura S, Matsuo H (1989) Establishment of radioimmunoassay for human islet amyloid polypeptide and its tissue content and plasma concentration. Biochem Biophys Res Commun 164: 394?399","journal-title":"Biochem Biophys Res Commun"},{"key":"CR30","doi-asserted-by":"crossref","first-page":"568","DOI":"10.2337\/diab.40.5.568","volume":"40","author":"S Frontoni","year":"1991","unstructured":"Frontoni S, Choi SB, Banduch D, Rossetti L (1991) In vivo insulin resistance induced by amylin primarily through inhibition of insulin-stimulated glycogen synthesis in skeletal muscle. Diabetes 40: 568?573","journal-title":"Diabetes"},{"key":"CR31","first-page":"434","volume":"52","author":"RD Fell","year":"1982","unstructured":"Fell RD, Terblanche SE, Ivy JL, Young JC, Holloszy JO (1982) Effect of muscle glycogen content on glucose uptake following exercise. J Appl Physiol (Respirat Environ Exercise Physiol) 52: 434?437","journal-title":"J Appl Physiol (Respirat Environ Exercise Physiol)"},{"key":"CR32","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1016\/0167-4889(84)90088-0","volume":"805","author":"JE Foley","year":"1984","unstructured":"Foley JE, Huecksteadt TP (1984) Glucose 6-phosphate effects on deoxyglucose, glucose, and methylglucose transport in rat adipocytes. Evidence for intracellular regulation of sugar transport by glucose metabolites. Biochem. Biophys Acta 805: 313?316","journal-title":"Biochem. Biophys Acta"},{"key":"CR33","doi-asserted-by":"crossref","first-page":"1183","DOI":"10.1016\/0026-0495(89)90157-1","volume":"38","author":"M Argyraki","year":"1989","unstructured":"Argyraki M, Wright PD, Venables CW, Proud G, Taylor R (1989) In vitro study of human skeletal muscle strips: Effect of nonesterified fatty acid supply on glucose storage. Metabolism 38: 1183?1187","journal-title":"Metabolism"},{"key":"CR34","volume-title":"Biochemistry for the medical sciences","author":"EA Newsholme","year":"1983","unstructured":"Newsholme EA, Leech AR (1983) Biochemistry for the medical sciences. John Wiley, Chichester New York"}],"container-title":["Diabetologia"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF00400848.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/BF00400848\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF00400848","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,6,28]],"date-time":"2021-06-28T01:38:51Z","timestamp":1624844331000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/BF00400848"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1992,1]]},"references-count":34,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1992,1]]}},"alternative-id":["BF00400848"],"URL":"https:\/\/doi.org\/10.1007\/bf00400848","relation":{},"ISSN":["0012-186X","1432-0428"],"issn-type":[{"value":"0012-186X","type":"print"},{"value":"1432-0428","type":"electronic"}],"subject":[],"published":{"date-parts":[[1992,1]]}}}