{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,11,16]],"date-time":"2023-11-16T19:02:43Z","timestamp":1700161363460},"reference-count":33,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[1989,8,1]],"date-time":"1989-08-01T00:00:00Z","timestamp":617932800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Cancer Res Clin Oncol"],"published-print":{"date-parts":[[1989,8]]},"DOI":"10.1007\/bf00400964","type":"journal-article","created":{"date-parts":[[2004,10,20]],"date-time":"2004-10-20T14:10:13Z","timestamp":1098281413000},"page":"366-372","source":"Crossref","is-referenced-by-count":2,"title":["Inhibited methionine incorporation in human squamous carcinomas of the oral cavity as a measure for response to 5-fluorouracil"],"prefix":"10.1007","volume":"115","author":[{"given":"T.","family":"G\ufffdr\ufffdgh","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. E.","family":"Eickbohm","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"Ewers","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B.","family":"Lippert","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E. E.","family":"Holdener","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"CR1","first-page":"197","volume-title":"Cloning of human tumor stem cells","author":"DS Alberts","year":"1980","unstructured":"Alberts DS, Chen HSG, Salmon SE (1980) In vitro drug assay: pharmacologic considerations. In: Salmon S (ed) Cloning of human tumor stem cells. Academic Press, New York, pp 197?207"},{"key":"CR2","doi-asserted-by":"crossref","first-page":"803","DOI":"10.1038\/bjc.1982.131","volume":"45","author":"I Bertoncello","year":"1982","unstructured":"Bertoncello I, Bradley TR, Campbell JJ, Day AJ, McDonal IA, Quinn MA, Rome R, Hodgson GS (1982) Limitations of the clonal agar assay for the assassment of primary human ovarian tumour biopsies. Br J Cancer 45:803?811","journal-title":"Br J Cancer"},{"key":"CR3","first-page":"196","volume":"20","author":"RN Buick","year":"1979","unstructured":"Buick RN, Fry SE, Salmon SE, Stanisic TH (1979a) A colony assay for progenitor cells from transitional cell carcinoma of the bladder. Proc Am Assoc Cancer Res 20:196","journal-title":"Proc Am Assoc Cancer Res"},{"key":"CR4","first-page":"5051","volume":"39","author":"RN Buick","year":"1979","unstructured":"Buick RN, Stanisic TH, Fry SE, Salmon SE, Trent JM, Krasovic P (1979b) Development of an agar-methyl cellulose clonogenic assay for cells in transitional cell carcinoma of the human bladder. Cancer Res 39:5051?5056","journal-title":"Cancer Res"},{"key":"CR5","doi-asserted-by":"crossref","first-page":"2357","DOI":"10.1002\/1097-0142(19860615)57:12<2357::AID-CNCR2820571220>3.0.CO;2-N","volume":"57","author":"ML Citron","year":"1986","unstructured":"Citron ML, Jaffe ND, Hamburger BSAW, Lindblad AL, Banda FP, Yenson A, Nathan KA, Cohen MH (1986) Improvement of human tumor cloning assay by suspension of fibroblasts into the bottom layer of agarose. Cancer 57:2357?2362","journal-title":"Cancer"},{"key":"CR6","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1038\/bjc.1978.165","volume":"38","author":"VD Courtenay","year":"1977","unstructured":"Courtenay VD, Selby PJ, Smith IE, Mils J, Peckham MJ (1977) Growth of human tumour cell colonies from biopsies using two soft agar techniques. Br J Cancer 38:77?81","journal-title":"Br J Cancer"},{"key":"CR7","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/0014-2964(79)90210-X","volume":"15","author":"B Drewinko","year":"1979","unstructured":"Drewinko B, Roper PR, Barlogie B (1979) Patterns of cell survival following treatment with antitumor agents in vitro. Europ J Cancer 15:93?99","journal-title":"Europ J Cancer"},{"key":"CR8","first-page":"389","volume":"12","author":"T G\ufffdr\ufffdgh","year":"1988","unstructured":"G\ufffdr\ufffdgh T, Eickbohm JE, Ewers R, Lippert B (1988) Aspekte des in-vitro Verhaltens von Plattenepithelcarcinomzellen aus Tumoren der Mundh\ufffdhle. Dtsch Z Mund-Kiefer-Gesichtschirurgie 12:389?396","journal-title":"Dtsch Z Mund-Kiefer-Gesichtschirurgie"},{"key":"CR9","doi-asserted-by":"crossref","first-page":"846","DOI":"10.1172\/JCI108839","volume":"60","author":"AW Hamburger","year":"1977","unstructured":"Hamburger AW, Salmon SE (1977a) Primary bioassay of human myeloma stem cells. J Clin Invest 60:846?854","journal-title":"J Clin Invest"},{"key":"CR10","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1126\/science.560061","volume":"197","author":"AW Hamburger","year":"1977","unstructured":"Hamburger AW, Salmon SE (1977b) Primary bioassay of human tumor stem cells. Science 197:461?463","journal-title":"Science"},{"key":"CR11","first-page":"3438","volume":"38","author":"AW Hamburger","year":"1978","unstructured":"Hamburger AW, Salmon SE, Kim MB, Trent JM, Soehnlen BJ, Alberts DS, Schmidt HJ (1978) Direct cloning of human ovarian carcinoma cells in soft agar, Cancer Res 38:3438?3444","journal-title":"Cancer Res"},{"key":"CR12","doi-asserted-by":"crossref","first-page":"1027","DOI":"10.1016\/0002-9343(81)90859-7","volume":"70","author":"DD Hoff v.","year":"1981","unstructured":"v. Hoff DD, Casper J, Sandbach J, Jones D, Makuck R (1981) Association between human tumor colony-forming assay results and response of individual patients tumor to chemotherapy. Am J Med 70:1027?1032","journal-title":"Am J Med"},{"key":"CR13","first-page":"1926","volume":"43","author":"DD Hoff v.","year":"1983","unstructured":"v. Hoff DD, Casper J, Mattox DE, Page CP, Cruz AB, Sandbach JF, Clark GM, Stogdill BJ, Sarosdy MF, O'Brien MT (1983) Prospective clinical trial of a human tumor cloning system. Cancer Res 43:1926?1931","journal-title":"Cancer Res"},{"key":"CR14","first-page":"310","volume":"41","author":"CL Laboisse","year":"1981","unstructured":"Laboisse CL, Augeron C, Potet F (1981) Growth and differentiation of human gastrointestinal adenocarcinoma stem cells in soft agarose. Cancer Res 41:310?315","journal-title":"Cancer Res"},{"key":"CR15","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1016\/0002-9610(80)90205-6","volume":"10","author":"DE Mattox","year":"1980","unstructured":"Mattox DE, v. Hoff DD (1980) In vitro stem cell assay in head and neck squamous carcinoma. Am J Surg 10:527?530","journal-title":"Am J Surg"},{"key":"CR16","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1203\/00006450-196809000-00004","volume":"2","author":"RM McAllister","year":"1968","unstructured":"McAllister RM, Reed G (1968) Colonial growth in agar of cells derived from neoplastic and non-neoplastic tissues of children. Pediatr Res 2:356?360","journal-title":"Pediatr Res"},{"key":"CR17","first-page":"379","volume":"22","author":"FR McKintosh","year":"1981","unstructured":"McKintosh FR, Louie AC, Evans TL, Amylon MD, Sikic BI (1981) Clonal heterogeneity in a human ovarian adenocarcinoma. Proc Am Assoc Cancer Res Am Soc Clin Oncol 22:379","journal-title":"Proc Am Assoc Cancer Res Am Soc Clin Oncol"},{"key":"CR18","first-page":"1976","volume":"28","author":"JH Madoc","year":"1981","unstructured":"Madoc JH, Bruce WR (1981) On the mechanism of the lethal action of 5-fluorouracil on mouse l-cells. Cancer Res 28:1976?1981","journal-title":"Cancer Res"},{"key":"CR19","first-page":"372","volume":"48","author":"M Osborn","year":"1983","unstructured":"Osborn M, Weber K (1983) Biology of disease. Tumor diagnosis by intermediate filament typing: a noval tool for surgical pathology. Lab Invest 48:372?394","journal-title":"Lab Invest"},{"key":"CR20","first-page":"137","volume":"34","author":"M Osborn","year":"1984","unstructured":"Osborn M, Debus E, Weber K (1984) Monoclonal antibodies specific for vimentin. Eur J Cell Biol 34:137?143","journal-title":"Eur J Cell Biol"},{"key":"CR21","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1002\/jcp.1040760111","volume":"76","author":"B Pike","year":"1970","unstructured":"Pike B, Robinson W (1970) Human bone marrow colony growth in vitro. J Cell Physiol 76:77?81","journal-title":"J Cell Physiol"},{"key":"CR22","first-page":"235","volume":"22","author":"P Reichard","year":"1962","unstructured":"Reichard P, Sk\ufffdld O, Klein G, Revesz L, Magnusson PH (1962) Studies on resistance against 5-fluorouracil. I. Enzymes of the uracil pathway during development of resistance. Cancer 22:235?243","journal-title":"Cancer"},{"key":"CR23","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1016\/0309-1651(80)90035-1","volume":"4","author":"HT Rupniak","year":"1980","unstructured":"Rupniak HT, Hill BT (1980) The poor cloning ability in agar of human tumour cells from biopsies of primary tumours. Cell Biol Int Rep 4:479?486","journal-title":"Cell Biol Int Rep"},{"key":"CR24","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1002\/ijc.2910320103","volume":"32","author":"HT Rupniak","year":"1983","unstructured":"Rupniak HT, Whelan RDH, Hill BT (1983) Concentration and time-dependent inter-relationships for antitumor drug cytotoxicities against tumor cells in vitro. Int J Cancer 32:7?12","journal-title":"Int J Cancer"},{"key":"CR25","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1038\/253461a0","volume":"253","author":"WC Russel","year":"1975","unstructured":"Russel WC, Newman C, Williamson DH (1975) A simple cytochemical technique for demonstration of DNA in cells infected with mycoplasmas and viruses. Nature 253:461?462","journal-title":"Nature"},{"key":"CR26","first-page":"377","volume":"8","author":"SE Salmon","year":"1981","unstructured":"Salmon SE, v. Hoff DD (1981) In vitro evaluation of anticancer drugs with the human tumor stem cell assay. Semin Oncol 8:377?385","journal-title":"Semin Oncol"},{"key":"CR27","doi-asserted-by":"crossref","first-page":"1321","DOI":"10.1056\/NEJM197806152982401","volume":"298","author":"SE Salmon","year":"1978","unstructured":"Salmon SE, Hamburger AW, Soehnlein B, Durie BGM, Alberts DS, Moon TE (1978) Quantitation of differential sensitivity of human-tumor stem cells to auticancer drugs. N Engl J Med 298:1321?1327","journal-title":"N Engl J Med"},{"key":"CR28","first-page":"340","volume":"20","author":"SE Salmon","year":"1979","unstructured":"Salmon SE, Soehnlen BJ, Durie BGM, Alberts DS, Meyskens FL, Chen HSG, Moon TE (1979) Clinical correlations of drug sensitivity in tumor stem cell assay. Proc Am Assoc Cancer Res 20:340","journal-title":"Proc Am Assoc Cancer Res"},{"key":"CR29","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/0092-8674(75)90086-0","volume":"5","author":"FG Scott","year":"1975","unstructured":"Scott FG, Migeon BR (1975) d-valine as a selective agent for normal human and rodent epithelial cells in culture. Cell 5:11?17","journal-title":"Cell"},{"key":"CR30","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1056\/NEJM198301203080304","volume":"308","author":"P Selby","year":"1983","unstructured":"Selby P, Buick RN, Tannock I (1983) A critical appraisal of the ?human tumor stem-cell assay?. N Engl J Med 308:129?134","journal-title":"N Engl J Med"},{"key":"CR31","volume-title":"Ovarian carcinoma cells in culture: Assessment of drug sensitivity by clonogenic assay","author":"AP Simmonds","year":"1984","unstructured":"Simmonds AP, McDonald EC (1984) Ovarian carcinoma cells in culture: Assessment of drug sensitivity by clonogenic assay. Macmillan, London"},{"key":"CR32","first-page":"1226","volume":"22","author":"O Sk\ufffdld","year":"1962","unstructured":"Sk\ufffdld O, Magnusson PH, Revesz L (1962) Studies on resistance against 5-fluorouracil. III. Selective value of resistant uridinekinase-deficient tumor cells. Cancer Res 22:1226?1229","journal-title":"Cancer Res"},{"key":"CR33","doi-asserted-by":"crossref","first-page":"476","DOI":"10.1038\/bjc.1976.201","volume":"34","author":"IE Smith","year":"1976","unstructured":"Smith IE, Courtenay VD, Gordon MY (1976) A colony-forming assay or human tumour xenografts using agar in diffusion chambers. Br J Cancer 34:476?483","journal-title":"Br J Cancer"}],"container-title":["Journal of Cancer Research and Clinical Oncology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF00400964.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/BF00400964\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF00400964","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,4,3]],"date-time":"2019-04-03T22:17:28Z","timestamp":1554329848000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/BF00400964"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1989,8]]},"references-count":33,"journal-issue":{"issue":"4","published-print":{"date-parts":[[1989,8]]}},"alternative-id":["BF00400964"],"URL":"https:\/\/doi.org\/10.1007\/bf00400964","relation":{},"ISSN":["0171-5216","1432-1335"],"issn-type":[{"value":"0171-5216","type":"print"},{"value":"1432-1335","type":"electronic"}],"subject":[],"published":{"date-parts":[[1989,8]]}}}