{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,7]],"date-time":"2026-09-07T20:35:07Z","timestamp":1788813307347,"version":"build-2803163510"},"reference-count":10,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[1990,2,1]],"date-time":"1990-02-01T00:00:00Z","timestamp":633830400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diabetologia"],"published-print":{"date-parts":[[1990,2]]},"DOI":"10.1007\/bf00401050","type":"journal-article","created":{"date-parts":[[2004,10,20]],"date-time":"2004-10-20T10:42:13Z","timestamp":1098268933000},"page":"115-117","source":"Crossref","is-referenced-by-count":72,"title":["Failure to establish islet amyloid polypeptide (amylin) as a circulating beta cell inhibiting hormone in man"],"prefix":"10.1007","volume":"33","author":[{"given":"D.","family":"Bretherton-Watt","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S. G.","family":"Gilbey","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M. A.","family":"Ghatei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Beacham","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S. R.","family":"Bloom","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"CR1","doi-asserted-by":"crossref","first-page":"3881","DOI":"10.1073\/pnas.84.11.3881","volume":"84","author":"P Westermark","year":"1987","unstructured":"Westermark P, Wernstedt C, Wilander E, Hayden DW, O'Brien TD, Johnson KH (1987) Amyloid fibrils in human insulinoma and islets of Langerhans of the diabetic cat are derived from a neuropeptide-like protein also present in normal cells. Proc Natl Acad Sci USA 84: 3881?3885","journal-title":"Proc Natl Acad Sci USA"},{"key":"CR2","doi-asserted-by":"crossref","first-page":"8628","DOI":"10.1073\/pnas.84.23.8628","volume":"84","author":"GJ Cooper","year":"1987","unstructured":"Cooper GJ, Willis AC, Clark A, Turner RC, Sim RB, Reid KB (1987) Purification and characterisation of a peptide from amyloid-rich pancreases of type-2 diabetic patients. Proc Natl Acad Sci USA 84: 8628?8632","journal-title":"Proc Natl Acad Sci USA"},{"key":"CR3","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1007\/BF00285291","volume":"32","author":"A Lukinius","year":"1989","unstructured":"Lukinius A, Wilander E, Westermark GT, Engstrom U, Westermark P (1989) Co-localisation of islet amyloid polypeptide in the B cell secretory granules of human pancreatic islets. Diabetologia 32: 240?244","journal-title":"Diabetologia"},{"key":"CR4","doi-asserted-by":"crossref","first-page":"7763","DOI":"10.1073\/pnas.85.20.7763","volume":"85","author":"GJS Cooper","year":"1988","unstructured":"Cooper GJS, Leighton B, Dimitriadis GD, Parry-Billings M, Kowalchuk JM, Howland K, Rothbard JB, Willis AC, Reid KBM (1988) Amylin found in amyloid deposits in human type 2 diabetes mellitus may be a hormone that regulates glycogen metabolism in skeletal muscle. Proc Natl Acad Sci USA 85: 7763?7766","journal-title":"Proc Natl Acad Sci USA"},{"key":"CR5","doi-asserted-by":"crossref","first-page":"961","DOI":"10.1016\/0006-291X(89)92529-1","volume":"160","author":"H Ohsawa","year":"1989","unstructured":"Ohsawa H, Kanatsuka A, Yamaguchi T, Makino H, Yoshida S (1989) Islet amyloid polypeptide inhibits glucose-stimulated insulin secretion from isolated rat pancreatic islets. Biochem Biophys Res Commun 160: 961?967","journal-title":"Biochem Biophys Res Commun"},{"key":"CR6","doi-asserted-by":"crossref","first-page":"1507","DOI":"10.1136\/bmj.1.5291.1507","volume":"2","author":"K Lundbaek","year":"1962","unstructured":"Lundbaek K (1962) Intravenous glucose tolerance as a tool in definition and diagnosis of diabetes mellitus. Br Med J 2: 1507?1513","journal-title":"Br Med J"},{"key":"CR7","first-page":"311","volume-title":"Principles of drug action","author":"A Goldstein","year":"1974","unstructured":"Goldstein A, Aronow L, Kalman SM (1974) Principles of drug action, 2nd edn. John Wiley, New York, p 311","edition":"2nd edn"},{"key":"CR8","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1016\/0014-5793(88)80922-0","volume":"239","author":"S Mosselman","year":"1988","unstructured":"Mosselman S, Hoppener JWM, Zandberg J, van Mansfield ADM, Geurts van Kessel AHM, Lips CJM, Jansz HS (1988) Islet amyloid polypeptide: identification and chromosomal localisation of the human gene. FEBS Lett 239: 227?232","journal-title":"FEBS Lett"},{"key":"CR9","doi-asserted-by":"crossref","first-page":"876","DOI":"10.1016\/0006-291X(89)92391-7","volume":"162","author":"HK Datta","year":"1989","unstructured":"Datta HK, Zaidi M, Wimalawansa SI, Ghatei MA, Beacham JL, Bloom SR, MacIntyre I (1989) In vivo and in vitro effects of amylin and amylin-amide on calcium metabolism in the rabbit. Biochem Biophys Res Commun 162: 876?881","journal-title":"Biochem Biophys Res Commun"},{"key":"CR10","doi-asserted-by":"crossref","first-page":"1300","DOI":"10.1016\/S0140-6736(87)91194-9","volume":"II","author":"B Kreymann","year":"1987","unstructured":"Kreymann B, Ghatei MA, Williams G, Bloom SR (1987) Glucagon-like peptide-1 (7?36): a physiological incretin in man. Lancet II: 1300?1303","journal-title":"Lancet"}],"container-title":["Diabetologia"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF00401050.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/BF00401050\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF00401050","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,4,3]],"date-time":"2019-04-03T18:17:31Z","timestamp":1554315451000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/BF00401050"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1990,2]]},"references-count":10,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1990,2]]}},"alternative-id":["BF00401050"],"URL":"https:\/\/doi.org\/10.1007\/bf00401050","relation":{},"ISSN":["0012-186X","1432-0428"],"issn-type":[{"value":"0012-186X","type":"print"},{"value":"1432-0428","type":"electronic"}],"subject":[],"published":{"date-parts":[[1990,2]]}}}