{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,16]],"date-time":"2026-01-16T10:23:52Z","timestamp":1768559032740,"version":"3.49.0"},"reference-count":17,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[1970,1,1]],"date-time":"1970-01-01T00:00:00Z","timestamp":0},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Psychopharmacologia"],"published-print":{"date-parts":[[1970]]},"DOI":"10.1007\/bf00412672","type":"journal-article","created":{"date-parts":[[2004,11,9]],"date-time":"2004-11-09T02:50:38Z","timestamp":1099968638000},"page":"260-270","source":"Crossref","is-referenced-by-count":24,"title":["Chlorpromazine in chronic schizophrenia: Behavioral dose-response relationships"],"prefix":"10.1007","volume":"18","author":[{"given":"Mervin L.","family":"Clark","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.","family":"Rudy Ramsey","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert E.","family":"Ragland","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Don K.","family":"Rahhal","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eustace A.","family":"Serafetinides","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Paul Costiloe","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"CR1","first-page":"146","volume":"16","author":"F. Ayd","year":"1955","unstructured":"Ayd, F.: Large doses of chlorpromazine in the treatment of psychiatric patients. Dis. nerv. Syst. 16, 146?149 (1955).","journal-title":"Dis. nerv. Syst."},{"key":"CR2","first-page":"5","volume":"11","author":"R. K. Brotman","year":"1969","unstructured":"Brotman, R. K., Muzekari, L. H., Shauken, P. M.: Butaperazine in chronic schizophrenic patients. A double-blind study. Curr. ther. Res. 11, 5?8 (1969).","journal-title":"Curr. ther. Res."},{"key":"CR3","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1007\/BF00592679","volume":"2","author":"M. L. Clark","year":"1961","unstructured":"Clark, M. L., Ray, T. S., Paredes, A., Costiloe, J. P., Chappell, J. S., Hagans, J. A., Wolf, S.: Chlorpromazine in chronic schizophrenic women: Experimental design and effects at maximum point of treatment. Psychopharmacologia (Berl.) 2, 107?137 (1961).","journal-title":"Psychopharmacologia (Berl.)"},{"key":"CR4","doi-asserted-by":"crossref","first-page":"261 to 281","DOI":"10.2307\/2527916","volume":"13","author":"W. G. Cochran","year":"1957","unstructured":"Cochran, W. G.: Analysis of covariance. Its nature and use. Biometrics 13, 261 to 281 (1957).","journal-title":"Biometrics"},{"key":"CR5","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1176\/ajp.121.1.33","volume":"121","author":"F. M. Forrest","year":"1964","unstructured":"Forrest, F. M., Geiter, C. W., Snow, H. L., Steinbach, M.: Drug maintenance problems of rehabilitated mental patients: The current drug-dosage ?merry-go-round?. Amer. J. Psychiat. 121, 33?40 (1964).","journal-title":"Amer. J. Psychiat."},{"key":"CR6","first-page":"23","volume":"2","author":"S. C. Goldberg","year":"1963","unstructured":"Goldberg, S. C., Cole, J. O., Clyde, D. J.: Factor analysis of ratings of schizophrenic behavior. Psychopharmacol. Serv. Cent. Bull. 2, 23?28 (1963).","journal-title":"Psychopharmacol. Serv. Cent. Bull."},{"key":"CR7","first-page":"53","volume":"1","author":"V. Kinross-Wright","year":"1955","unstructured":"Kinross-Wright, V.: The intensive chlorpromazine treatment of schizophrenia. Psychiat. Res. Rep. Amer. psychiat. Ass. 1, 53?62 (1955).","journal-title":"Psychiat. Res. Rep. Amer. psychiat. Ass."},{"key":"CR8","doi-asserted-by":"crossref","first-page":"512","DOI":"10.1136\/bmj.1.4965.512","volume":"1","author":"D. Lieberman","year":"1956","unstructured":"Lieberman, D.: Tranquilizers in psychiatry: Chlorpromazine therapy. Brit. J. Med. 1, 512?513 (1956).","journal-title":"Brit. J. Med."},{"key":"CR9","unstructured":"Lorr, M., Klett, C. J., McNair, D. M., Lasky, J. J.: Inpatient multi-dimensional psychiatric scale. Manual, Veterans Administration, 1962."},{"key":"CR10","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1097\/00000441-196510000-00011","volume":"250","author":"J. H. Nodine","year":"1965","unstructured":"Nodine, J. H., Siegler, P. E., Bodi, T., Mapp, Y., Dykyj, R.: A variable dose phase 3, human bioassay of nortriptyline. Amer. J. med. Sci. 250, 443?447 (1965).","journal-title":"Amer. J. med. Sci."},{"key":"CR11","doi-asserted-by":"crossref","first-page":"799","DOI":"10.2466\/pr0.1962.10.3.799","volume":"10","author":"J. E. Overall","year":"1962","unstructured":"Overall, J. E., Gorham, D. R.: The brief psychiatric rating scale. Psychol. Rep. 10, 799?812 (1962).","journal-title":"Psychol. Rep."},{"key":"CR12","doi-asserted-by":"crossref","first-page":"482","DOI":"10.1001\/archpsyc.1968.01740040098013","volume":"18","author":"R. F. Prien","year":"1968","unstructured":"Prien, R. F., Cole, J. O.: High dose chlorpromazine therapy in chronic schizophrenia: Report of NIMH PRB collaborative study group. Arch. gen. Psychiat. 18, 482?495 (1968).","journal-title":"Arch. gen. Psychiat."},{"key":"CR13","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1176\/ajp.126.3.305","volume":"126","author":"R. F. Prien","year":"1969","unstructured":"?, Levine, J., Cole, J. O.: High dose trifluoperazine therapy in chronic schizophrenia. Amer. J. Psychiat. 126, 305?313 (1969).","journal-title":"Amer. J. Psychiat."},{"key":"CR14","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1192\/bjp.110.464.61","volume":"110","author":"D. Rosati","year":"1964","unstructured":"Rosati, D.: Prolonged high dosage ataractic medication in chronic schizophrenia. Brit. J. Psychiat. 110, 61?63 (1964).","journal-title":"Brit. J. Psychiat."},{"key":"CR15","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1007\/BF01575453","volume":"33","author":"B. C. Schiele","year":"1959","unstructured":"Schiele, B. C., Mendelson, R. M., Penman, A. S., Schofleld, W.: Comparison of low and high dosage procedures in chlorpromazine therapy. Psychiat. Quart. 33, 252?259 (1959).","journal-title":"Psychiat. Quart."},{"key":"CR16","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1037\/11774-000","volume-title":"Statistical principles in experimental design","author":"B. J. Winer","year":"1962","unstructured":"Winer, B. J.: Statistical principles in experimental design, p. 585. New York: McGraw-Hill Book Co. 1962."},{"key":"CR17","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1037\/11774-000","volume-title":"Statistical principles in experimental design","author":"B. J. Winer","year":"1962","unstructured":"?: Statistical principles in experimental design, pp. 101?104. New York: McGraw Hill Book Co. 1962."}],"container-title":["Psychopharmacologia"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF00412672.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/BF00412672\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF00412672","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,4,9]],"date-time":"2019-04-09T03:19:46Z","timestamp":1554779986000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/BF00412672"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1970]]},"references-count":17,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1970]]}},"alternative-id":["BF00412672"],"URL":"https:\/\/doi.org\/10.1007\/bf00412672","relation":{},"ISSN":["0033-3158","1432-2072"],"issn-type":[{"value":"0033-3158","type":"print"},{"value":"1432-2072","type":"electronic"}],"subject":[],"published":{"date-parts":[[1970]]}}}