{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T22:08:58Z","timestamp":1790028538078,"version":"4.0.1"},"reference-count":33,"publisher":"Springer Science and Business Media LLC","issue":"2-3","license":[{"start":{"date-parts":[[1980,12,1]],"date-time":"1980-12-01T00:00:00Z","timestamp":344476800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Europ. J. Appl. Physiol."],"published-print":{"date-parts":[[1980,12]]},"DOI":"10.1007\/bf00421324","type":"journal-article","created":{"date-parts":[[2004,11,10]],"date-time":"2004-11-10T02:02:30Z","timestamp":1100052150000},"page":"167-176","source":"Crossref","is-referenced-by-count":54,"title":["Influence of exposure to moderate altitude on the plasma concentration of cortisol, aldosterone, renin, testosterone, and gonadotropins"],"prefix":"10.1007","volume":"45","author":[{"given":"E.","family":"Humpeler","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F.","family":"Skrabal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.","family":"Bartsch","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"CR1","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1038\/191078b0","volume":"191","author":"PJ Ayres","year":"1961","unstructured":"Ayres PJ, Hunter RC, Williams ES, Rundo J (1961) Aldosterone excretion and potassium retention in subjects living at high altitude. Nature 191: 78?80","journal-title":"Nature"},{"key":"CR2","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1677\/joe.0.0790147","volume":"79","author":"CRM Bangham","year":"1978","unstructured":"Bangham CRM, Hackett PH (1978) Effect of high altitude on endocrine functions in the sherpas of Nepal. J Endocrinol 79: 147?148","journal-title":"J Endocrinol"},{"key":"CR3","doi-asserted-by":"crossref","first-page":"1223","DOI":"10.1210\/endo-92-4-1223","volume":"92","author":"A Bartke","year":"1973","unstructured":"Bartke A, Steele RE, Musto N, Caldwell EV (1973) Fluctuations in plasma testosterone levels in adult male rats and mice. Endocrinology 92: 1223?1228","journal-title":"Endocrinology"},{"key":"CR4","first-page":"213","volume":"1","author":"GW Boyd","year":"1966","unstructured":"Boyd GW, Adamson AR, Fitz AE, Peart WS (1966) Radioimmunoassay determination of plasma-renin activity. Lancet 1: 213","journal-title":"Lancet"},{"key":"CR5","first-page":"209","volume":"8","author":"DL Costill","year":"1976","unstructured":"Costill DL, Branam G, Fink W, Nelson R (1976) Exercise induced sodium conservation: changes in plasma renin and aldosterone. Med Sci Sports 8: 209?213","journal-title":"Med Sci Sports"},{"key":"CR6","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1210\/jcem-30-2-153","volume":"30","author":"PG Crosignani","year":"1970","unstructured":"Crosignani PG, Nakamura R, Hovland T, Mishell FR (1970) A method of solide phase radioimmunoassay utilizing polypropylene discs. J Clin Endocrinol Metab 30: 153?160","journal-title":"J Clin Endocrinol Metab"},{"key":"CR7","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1210\/endo-85-2-381","volume":"85","author":"JW Funder","year":"1969","unstructured":"Funder JW (1969) Effect of plasma K+ on the secretion of aldosterone. Endocrinology 85: 381?384","journal-title":"Endocrinology"},{"key":"CR8","first-page":"443","volume":"22","author":"AB Gould","year":"1970","unstructured":"Gould AB, Goodman SA (1970) The effect of hypoxia on the renin-angiotensinogen system. Lab Invest 22: 443?447","journal-title":"Lab Invest"},{"key":"CR9","doi-asserted-by":"crossref","first-page":"652","DOI":"10.1152\/jappl.1978.44.5.652","volume":"44","author":"JE Greenleaf","year":"1978","unstructured":"Greenleaf JE, Bernauer EM, Adams WC, Juhos L (1978) Fluid-electrolyte shifts and VO2 max in man at simulated altitude (2,287 m). J Appl Physiol 44: 652?658","journal-title":"J Appl Physiol"},{"key":"CR10","first-page":"55","volume":"2","author":"R Guerra-Garcia","year":"1971","unstructured":"Guerra-Garcia R (1971) Testosterone metabolism in men exposed to high altitude. Acta Endocrinol Panam 2: 55","journal-title":"Acta Endocrinol Panam"},{"key":"CR11","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1016\/B978-1-4831-6699-5.50018-8","volume-title":"Physiological effects of high altitude","author":"MJ Halhuber","year":"1964","unstructured":"Halhuber MJ, Gabl F (1964) 17-OHCS excretion and blood eosinophils at an altitude of 2,000 m. In: Weihe WH (ed) Physiological effects of high altitude. Pergamon Press, Oxford, pp 131?138"},{"key":"CR12","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1210\/jcem-34-1-106","volume":"34","author":"T Ito","year":"1972","unstructured":"Ito T, Woo J, Haning R, Horton R (1972) A radioimmunoassay for aldosterone in human peripheral plasma including a comparison of alternate techniques. J Clin Endocrinol 34: 106","journal-title":"J Clin Endocrinol"},{"key":"CR13","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1152\/jappl.1971.31.4.593","volume":"31","author":"RC Jung","year":"1971","unstructured":"Jung RC, Dill DB, Horton R, Horvath SM (1971) Effects of age on plasma aldosterone levels and hemoconcentration at altitude. J Appl Physiol 31: 593?597","journal-title":"J Appl Physiol"},{"key":"CR14","doi-asserted-by":"crossref","first-page":"1477","DOI":"10.1210\/endo-91-6-1447","volume":"91","author":"GJ Klain","year":"1972","unstructured":"Klain GJ (1972) Acute high altitude stress and enzyme activities in the rat adrenal medulla. Endocrinology 91: 1477?1449","journal-title":"Endocrinology"},{"key":"CR15","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1530\/acta.0.0160118","volume":"16","author":"F Koller","year":"1954","unstructured":"Koller F, Schwarz E, Marti M (1954) \ufffdber die Reaktion der NNR beim Aufstieg im Hochgebirge. Acta Endocrinol 16: 118?140","journal-title":"Acta Endocrinol"},{"key":"CR16","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1152\/jappl.1976.41.1.26","volume":"41","author":"KJ Kosunen","year":"1976","unstructured":"Kosunen KJ, Pakarinen AJ (1976) Plasma renin, angiotensin II, and plasma and urinary aldosterone in running exercise. J Appl Physiol 41: 26?29","journal-title":"J Appl Physiol"},{"key":"CR17","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1677\/joe.0.0260555","volume":"26","author":"PCB McKinnon","year":"1963","unstructured":"McKinnon PCB, Monk-Jones ME, Fotherby K (1963) A study of various indices of adrenocortical activity during 23 days at high altitude. J Endicrinol 26: 555?566","journal-title":"J Endicrinol"},{"key":"CR18","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1152\/jappl.1975.39.1.18","volume":"39","author":"JT Maher","year":"1975","unstructured":"Maher JT, Jones LG, Hartley LH, Williams GH, Rose LI (1975) Aldosterone dynamics during graded exercises at sea level and high altitude. J Appl Physiol 39: 18?22","journal-title":"J Appl Physiol"},{"key":"CR19","doi-asserted-by":"crossref","first-page":"1640","DOI":"10.1210\/jcem-25-12-1640","volume":"25","author":"F Moncloa","year":"1965","unstructured":"Moncloa F, Donayre J, Sobrevilla LA, Guerra-Garcia R (1965) Endocrine studies at high altitude. II. Adrenal cortical function in sea-level natives exposed to high altitudes (4,300 m) for two weeks. J Clin Endicrinol Metab 25: 1640?1642","journal-title":"J Clin Endicrinol Metab"},{"key":"CR20","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1210\/jcem-28-3-379","volume":"28","author":"F Moncloa","year":"1968","unstructured":"Moncloa F, Velasco I, Beteta L (1968) Plasma cortisol concentration and disappearance rate of 4-14C-cortisol in newcomers to high altitude. J Clin Endiocrinol Metab 28: 379","journal-title":"J Clin Endiocrinol Metab"},{"key":"CR21","doi-asserted-by":"crossref","first-page":"973","DOI":"10.1210\/jcem-27-7-973","volume":"27","author":"BEP Murphy","year":"1967","unstructured":"Murphy BEP (1967) Some studies of the protein binding of steroids and their routine micro- and ultra-micromeasurements of various steroids of body fluids by competitive protein binding radio-assay. J Clin Endocrinol Metab 27: 973","journal-title":"J Clin Endocrinol Metab"},{"key":"CR22","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1210\/jcem-44-3-447","volume":"44","author":"GK Rastogi","year":"1977","unstructured":"Rastogi GK, Malhotra MS, Srivastava MC, Sawhney RC, Dua GL, Sridharan K, Hoon RS, Singh I (1977) Study of the pituitarythyroid functions at high altitude in man. J Clin Endocrinol Metab 44: 447?452","journal-title":"J Clin Endocrinol Metab"},{"key":"CR23","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1007\/978-3-662-00040-3","volume-title":"Statistische Auswertungsmethoden","author":"L Sachs","year":"1968","unstructured":"Sachs L (1968) Statistische Auswertungsmethoden. Springer, Berlin Heidelberg New York, pp 293"},{"key":"CR24","first-page":"C72","volume":"8","author":"E Sailer","year":"1950","unstructured":"Sailer E, Verz\ufffdr F (1950) Die Ausscheidung von Corticosteroiden in Ruhe, bei Muskelarbeit und in der H\ufffdhe. Helv Phys Acta 8: C72-C74","journal-title":"Helv Phys Acta"},{"key":"CR25","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1007\/BF01453935","volume":"18","author":"I Singh","year":"1974","unstructured":"Singh I, Malhotra MS, Khanna PK, Nanda RB, Purshottam T, Upadhyay TN, Radhakrishnan U, Brahmachari DH (1974) Changes in plasma cortisol, blood antidiuretic hormone, and urinary catecholamines in high altitude pulmonary oedema. Int J Biometeorol 18: 211?221","journal-title":"Int J Biometeorol"},{"key":"CR26","first-page":"2649","volume":"100","author":"F Skrabal","year":"1975","unstructured":"Skrabal F (1975) Nomogramm zur Sch\ufffdtzung der Plasmareninaktivit\ufffdt anhand des Natrium-Kreatinin-Quotienten im Spontanharn. Dtsch Med Wochenschr 100: 2649?2651","journal-title":"Dtsch Med Wochenschr"},{"key":"CR27","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1177\/014107687907200404","volume":"72","author":"F Skrabal","year":"1979","unstructured":"Skrabal F (1979) Aldosterone and in vivo mineralocorticoid activity in normotensive and hypertensive man. J R Soc Med 72: 252?259","journal-title":"J R Soc Med"},{"key":"CR28","first-page":"327","volume":"37","author":"JDH Slater","year":"1969","unstructured":"Slater JDH, Tuffley RE, Edwards RHT, Ekins RP, Beresford CH, S\ufffdnksen PH, Williams ES, McLaughlin M (1969) Control of aldosterone secretion during acclimatization to hypoxia in man. Clin Sci 37: 327?341","journal-title":"Clin Sci"},{"key":"CR29","first-page":"47","volume":"2","author":"LA Sobrevilla","year":"1971","unstructured":"Sobrevilla LA, Midgley AR (1971) The plasma gonadotropin response to high altitude exposure. Acta Endocrinol Panam 2: 47","journal-title":"Acta Endocrinol Panam"},{"key":"CR30","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1007\/BF00423120","volume":"36","author":"U Tibes","year":"1977","unstructured":"Tibes U, Hemmer B, B\ufffdning D (1977) Heart rate and ventilation of relation to venous K+, osmolality, pH, Pco2 Po2 exercise in athletes and non-athletes. Eur J Appl Physiol 36: 127","journal-title":"Eur J Appl Physiol"},{"key":"CR31","first-page":"340","volume":"16","author":"PS Timiras","year":"1957","unstructured":"Timiras PS, Pace NG, Hwang CA (1957) Plasma and urine 17-hydroxycorticosteroid and urine 17-ketosteroid levels in man during acclimatization to high altitude. Federation Proceedings, Federation of American Societies for Experimental Biology 16: 340","journal-title":"Federation Proceedings, Federation of American Societies for Experimental Biology"},{"key":"CR32","first-page":"356","volume":"49","author":"AJ Vander","year":"1978","unstructured":"Vander AJ, Moore LG, Brewer G, Menon KMJ, England BG (1978) Effects of high altitude on plasma concentrations of testosterone and pituitary gonadotropins in man. Aviat Space Environ Med 49: 356?357","journal-title":"Aviat Space Environ Med"},{"key":"CR33","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1098\/rspb.1966.0068","volume":"165","author":"ES Williams","year":"1966","unstructured":"Williams ES (1966) Electrolyte regulation during the adaptation of humans to life at high altitudes. Proc R Soc London Ser B 165: 266?280","journal-title":"Proc R Soc London Ser B"}],"container-title":["European Journal of Applied Physiology and Occupational Physiology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF00421324.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/BF00421324\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF00421324","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,4,3]],"date-time":"2019-04-03T23:58:07Z","timestamp":1554335887000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/BF00421324"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1980,12]]},"references-count":33,"journal-issue":{"issue":"2-3","published-print":{"date-parts":[[1980,12]]}},"alternative-id":["BF00421324"],"URL":"https:\/\/doi.org\/10.1007\/bf00421324","relation":{},"ISSN":["0301-5548","1439-6327"],"issn-type":[{"value":"0301-5548","type":"print"},{"value":"1439-6327","type":"electronic"}],"subject":[],"published":{"date-parts":[[1980,12]]}}}