{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T07:31:54Z","timestamp":1778571114417,"version":"3.51.4"},"reference-count":28,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[1981,5,1]],"date-time":"1981-05-01T00:00:00Z","timestamp":357523200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Europ. J. Appl. Physiol."],"published-print":{"date-parts":[[1981,5]]},"DOI":"10.1007\/bf00428864","type":"journal-article","created":{"date-parts":[[2004,11,10]],"date-time":"2004-11-10T22:23:18Z","timestamp":1100125398000},"page":"105-119","source":"Crossref","is-referenced-by-count":14,"title":["Propranolol and the respiratory, circulatory, and ECG responses to high altitude"],"prefix":"10.1007","volume":"46","author":[{"given":"U.","family":"Boutellier","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E. A.","family":"Koller","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"CR1","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1161\/01.RES.11.2.247","volume":"11","author":"JA Abildskov","year":"1962","unstructured":"Abildskov JA, Klein RM (1962) Cancellation of electrocardiogram effects during ventricular exitation. Circ Res 11: 247?251","journal-title":"Circ Res"},{"key":"CR2","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1161\/01.RES.40.1.3","volume":"40","author":"JA Abildskov","year":"1977","unstructured":"Abildskov JA, Burgess MJ, Urie PM, Lux RL, Wyatt RF (1977) The unidentified information content of the electrocardiogram. Circ Res 40: 3?7","journal-title":"Circ Res"},{"key":"CR3","doi-asserted-by":"crossref","first-page":"747","DOI":"10.1172\/JCI107237","volume":"52","author":"G Bodem","year":"1973","unstructured":"Bodem G, Brannell HL, Weil JV, Chidsey CA (1973) Pharmacodynamic studies of beta-adrenergic antagonism induced in man by propranolol and practolol. J Clin Invest 52: 747?752","journal-title":"J Clin Invest"},{"key":"CR4","first-page":"1327","volume":"95","author":"A B\u00fchlmann","year":"1965","unstructured":"B\u00fchlmann A (1965) Klinische Funktionspr\u00fcfung des Herzens. Schweiz Med Wochenschr 95: 1327?1332","journal-title":"Schweiz Med Wochenschr"},{"key":"CR5","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/S0022-0736(69)81005-8","volume":"2","author":"MJ Burgess","year":"1969","unstructured":"Burgess MJ, Millar K, Abildskov JA (1969) Cancellation of electrocardiogram effects during ventricular recovery. J Electrocardiol 2: 101?108","journal-title":"J Electrocardiol"},{"key":"CR6","first-page":"267","volume":"3","author":"EN Chamberlain","year":"1938","unstructured":"Chamberlain EN (1938) The results of sympathetic stimulation and extirpation on the human electrocardiogram. Clin Sci 3: 267?269","journal-title":"Clin Sci"},{"key":"CR7","doi-asserted-by":"crossref","first-page":"607","DOI":"10.1152\/jappl.1965.20.4.607","volume":"20","author":"W Cunningham","year":"1965","unstructured":"Cunningham W, Becker E, Kreuzer R (1965) Catecholamines in plasma and urine at high altitude. J Appl Physiol 20: 607?610","journal-title":"J Appl Physiol"},{"key":"CR8","first-page":"208","volume-title":"Autonomic influences on cardiac function in systemic hypoxia","author":"SE Downing","year":"1966","unstructured":"Downing SE (1966) Autonomic influences on cardiac function in systemic hypoxia. In: Hatcher JD, Jennings DB (eds) Proceedings of the International Symposium on the Cardiovascular and Respiratory Effects of Hypoxia. Karger, Basel New York, pp. 208?231"},{"key":"CR9","volume-title":"Beta-Rezeptoren-Blockade. Kreislauf-B\u00fccherei, Bd 23","author":"W Gebhardt","year":"1967","unstructured":"Gebhardt W, Reindell H, B\u00fcchner Ch, K\u00f6nig K (1967) Untersuchungen \u00fcber den Effekt von Propranolol auf die Dynamik von Herz und Kreislauf. In: Beta-Rezeptoren-Blockade. Kreislauf-B\u00fccherei, Bd 23. Steinkopff, Darmstadt"},{"key":"CR10","first-page":"1","volume":"132","author":"R Hegglin","year":"1937","unstructured":"Hegglin R, Holzmann M (1937) Die klinische Bedeutung der verl\u00c4ngerten QT-Distanz (Systolendauer) im Elektrokardiogramm. Z Klin Med 132: 1?32","journal-title":"Z Klin Med"},{"key":"CR11","doi-asserted-by":"crossref","first-page":"1173","DOI":"10.1161\/01.CIR.48.6.1173","volume":"48","author":"ChR Jorgensen","year":"1973","unstructured":"Jorgensen ChR, Wang K, Wang Y, Gobel FL, Nelson RR, Taylor H (1973) Effect of propranolol on myocardial oxygen consumption and its hemodynamic correlates during upright exercise. Circulation 48: 1173?1182","journal-title":"Circulation"},{"key":"CR12","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1161\/01.RES.46.2.190","volume":"46","author":"T Kumada","year":"1980","unstructured":"Kumada T, Gallagher KP, Shirato K, McKown D, Miller M, Kemper WS, White F, Ross J (1980) Reduction of exercise-induced regional myocardial dysfunction by propanolol. Circ Res 46: 190?200","journal-title":"Circ Res"},{"key":"CR13","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1152\/jappl.1976.41.2.159","volume":"41","author":"P Laciga","year":"1976","unstructured":"Laciga P, Koller EA (1976) Respiratory, circulatory, and ECG changes during acute exposure to high altitude. J Appl Physiol 41: 159?167","journal-title":"J Appl Physiol"},{"key":"CR14","first-page":"900","volume":"34","author":"P Laciga","year":"1978","unstructured":"Laciga P, Koller EA (1978) Respiratory, circulatory, and ECG changes at 6,000 m and 7,000 m. Experientia 34: 900 [Abstract]","journal-title":"Experientia"},{"key":"CR15","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1002\/cpt1975176709","volume":"17","author":"MM Winter Le","year":"1975","unstructured":"Le Winter MM, Crawford MH, Karliner JS, O'Rourke RA (1975) Effects of oral propranolol in normal subjects. Clin Pharmacol Ther 17: 709?712","journal-title":"Clin Pharmacol Ther"},{"key":"CR16","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1016\/S0002-8703(77)80312-8","volume":"93","author":"MM Winter Le","year":"1977","unstructured":"Le Winter MM, Crawford MH, O'Rourke RA, Karliner JS (1977) The effects of oral propranolol, digoxin and combination therapy on the resting and exercise electrocardiogram. Am Heart J 93: 202?209","journal-title":"Am Heart J"},{"key":"CR17","first-page":"128","volume":"25","author":"MJ Montano","year":"1975","unstructured":"Montano MJ, Alperin M, Aggio MC (1975) Effect of beta-adrenergic blockade on surviving to acute hypoxia in mice. Acta Physiol Lat Am 25: 128?133","journal-title":"Acta Physiol Lat Am"},{"key":"CR18","first-page":"1564","volume":"106","author":"PR Moret","year":"1976","unstructured":"Moret PR, Duchosal F (1976) Effets du propranolol sur l'hypertension pulmonaire, l'hypertrophie ventriculaire droite et les alt\u00e9rations m\u00e9taboliques myocardiques dues \u00e0 l'hypox\u00e9mie aigu\u00cb de haute altitude. Schweiz Med Wochenschr 106: 1564?1566","journal-title":"Schweiz Med Wochenschr"},{"key":"CR19","first-page":"288","volume-title":"Die Betablocker ? Gegenwart und Zukunft","author":"W Riess","year":"1976","unstructured":"Riess W, Brechb\u00fchl S, Brunner L, Imhof PR, Jack DB (1976) Der Metabolismus von beta-adrenolytischen Substanzen in Zusammenhang mit ihrem pharmakokinetischen und pharmakodynamischen Verhalten. In: Schweizer W (Hrsg) Die Betablocker ? Gegenwart und Zukunft. Huber, Bern Stuttgart Wien, pp 288?300"},{"key":"CR20","first-page":"71","volume":"1","author":"K Sangvik","year":"1976","unstructured":"Sangvik K, Stokkeland M, Lindseth E-M, Nyberg G (1976) Circulation reaction at rest and during isometric and dynamic exercise in hypertensive patients: influence of different adrenergic beta-adrenoceptor antagonists. Pharmatherapeutica 1: 71?83","journal-title":"Pharmatherapeutica"},{"key":"CR21","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1007\/BF00363488","volume":"255","author":"H Schaefer","year":"1952","unstructured":"Schaefer H (1952) \u00fcber die absolute Gr\u00f6\\e elektrokardiographischer Potentiale. Pfl\u00fcgers Arch 255: 251?272","journal-title":"Pfl\u00fcgers Arch"},{"key":"CR22","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1002\/cpt1970111112","volume":"11","author":"DG Shand","year":"1970","unstructured":"Shand DG, Nuckolls EM, Oates JA (1970) Plasma propranolol levels in adults with observations in four children. Clin Pharmacol Ther 11: 112?120","journal-title":"Clin Pharmacol Ther"},{"key":"CR23","first-page":"143","volume":"22","author":"T Sj\u00f6strand","year":"1956","unstructured":"Sj\u00f6strand T (1956) Die pathologische Physiologie der Korrelation zwischen Herz und Gef\u00c4\\system. Verh Dtsch Ges Kreislaufforsch 22: 143?157","journal-title":"Verh Dtsch Ges Kreislaufforsch"},{"key":"CR24","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1016\/0002-8703(69)90350-0","volume":"77","author":"S Stern","year":"1969","unstructured":"Stern S, Eisenberg S (1969) The effect of propranolol (Inderal) on the electrocardiogram of normal subjects. Am Heart J 77: 192?195","journal-title":"Am Heart J"},{"key":"CR25","first-page":"349","volume":"15","author":"JC Stickney","year":"1972","unstructured":"Stickney JC (1972) Some problems of homeostasis in high altitude exposure. Physiologist 15: 349?359 [Abstract]","journal-title":"Physiologist"},{"key":"CR26","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1152\/jappl.1973.34.5.619","volume":"34","author":"DJ Stone","year":"1973","unstructured":"Stone DJ, Keltz H, Sarkar TK, Singzon J (1973) Ventilatory response to alpha-adrenergic stimulation and inhibition. J Appl Physiol 34: 619?623","journal-title":"J Appl Physiol"},{"key":"CR27","volume-title":"Hypoxia","author":"EJ Liere Van","year":"1963","unstructured":"Van Liere EJ, Stickney JC (1963) Hypoxia. Univ. of Chicago Press, Chicago London"},{"key":"CR28","doi-asserted-by":"crossref","first-page":"813","DOI":"10.1152\/jappl.1972.33.6.813","volume":"33","author":"JV Weil","year":"1972","unstructured":"Weil JV, Byrne-Quinn E, Sodal IE, Kline JS, McCullough RE, Filley GF (1972) Augmentation of chemosensitivity during mild exercise in normal man. J Appl Physiol 33: 813?819","journal-title":"J Appl Physiol"}],"container-title":["European Journal of Applied Physiology and Occupational Physiology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF00428864.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/BF00428864\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF00428864","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,4,9]],"date-time":"2019-04-09T18:38:25Z","timestamp":1554835105000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/BF00428864"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1981,5]]},"references-count":28,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1981,5]]}},"alternative-id":["BF00428864"],"URL":"https:\/\/doi.org\/10.1007\/bf00428864","relation":{},"ISSN":["0301-5548","1439-6327"],"issn-type":[{"value":"0301-5548","type":"print"},{"value":"1439-6327","type":"electronic"}],"subject":[],"published":{"date-parts":[[1981,5]]}}}