{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,7]],"date-time":"2026-02-07T02:24:37Z","timestamp":1770431077982,"version":"3.49.0"},"reference-count":35,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[1975,10,1]],"date-time":"1975-10-01T00:00:00Z","timestamp":181353600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diabetologia"],"published-print":{"date-parts":[[1975,10]]},"DOI":"10.1007\/bf00429913","type":"journal-article","created":{"date-parts":[[2004,11,11]],"date-time":"2004-11-11T05:39:04Z","timestamp":1100151544000},"page":"439-443","source":"Crossref","is-referenced-by-count":15,"title":["Diabetogenic effect and inhibition of insulin secretion induced in normal rats by ammonium infusions"],"prefix":"10.1007","volume":"11","author":[{"given":"J. L.","family":"Schlienger","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Imler","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Stahl","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"CR1","doi-asserted-by":"crossref","first-page":"893","DOI":"10.1016\/S0016-5085(19)33404-3","volume":"61","author":"O. Albano","year":"1971","unstructured":"Albano, O., Francavilla, A.: Intracellular potassium concentration during ammonia intoxication. Gastroenteroly 61, 893?897 (1971)","journal-title":"Gastroenteroly"},{"key":"CR2","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1042\/cs0390375","volume":"39","author":"G. A. O. Alleyne","year":"1970","unstructured":"Alleyne, G. A. O., Fraser, H. S., Besterman, H. S.: Some effect of metabolic acidosis on carbohydrate metabolism in the rat. Clin. Sci. 39, 375?382 (1970)","journal-title":"Clin. Sci."},{"key":"CR3","first-page":"714","volume":"48","author":"D. S. Amatuzio","year":"1956","unstructured":"Amatuzio, D. S., Rames, F. D., Nesbitt, S.: The practical application of the rapid intravenous glucose tolerance test in various states affecting glucose metabolism. J. Lab. clin. Med. 48, 714?720 (1956)","journal-title":"J. Lab. clin. Med."},{"key":"CR4","doi-asserted-by":"crossref","first-page":"622","DOI":"10.1172\/JCI103111","volume":"34","author":"S. P. Bessman","year":"1955","unstructured":"Bessman, S. P., Bessman, A. N.: Cerebral and peripheral uptake of ammonia in liver disease with a hypothesis of mechanism of hepatic coma. J. clin. Invest 34, 622?628 (1955)","journal-title":"J. clin. Invest"},{"key":"CR5","doi-asserted-by":"crossref","first-page":"1991","DOI":"10.1021\/bi00833a032","volume":"8","author":"R. L. Blakely","year":"1969","unstructured":"Blakely, R. L., Hinds, J. A., Kunze, H. E., Webb, E. C., Zerner, B.: Jackbean urease (E.C.3.5.1.5), demonstration of carbamyl transfer reaction and inhibition by hydroxamic acid. Biochemistry 8, 1991?1999 (1969)","journal-title":"Biochemistry"},{"key":"CR6","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1001\/jama.1967.03120090083015","volume":"199","author":"H. Brown","year":"1967","unstructured":"Brown, H., O'Hara, E., Brown, N. E., Covelli V. H., Konda, D., Mc Dermott, Jr. W. V.: Relation of blood glucose to blood ammonia and urea cycle enzymes. J. Amer. med. Ass. 199, 641?646 (1967)","journal-title":"J. Amer. med. Ass."},{"key":"CR7","first-page":"1886","volume":"148","author":"J. Christophe","year":"1954","unstructured":"Christophe, J.: D\ufffdtermination d'un coefficient d'assimilation glucidique chez le rat normal. Etude de l'influence de la dose de glucose sur l'assimilation. C. R. Soc. Biol. (Paris) 148, 1886?1889 (1954)","journal-title":"C. R. Soc. Biol. (Paris)"},{"key":"CR8","first-page":"301","volume":"28","author":"A. J. Clifford","year":"1969","unstructured":"Clifford, A. J., Prior, R. L., Visek, W. J.: Concentrations of metabolic intermediates in blood and liver of rats acutely intoxicated with ammonia (abstract). Fed. Proc. 28, 301 (1969)","journal-title":"Fed. Proc."},{"key":"CR9","doi-asserted-by":"crossref","unstructured":"Conard, V., Rasio, E., Franckson, J. R. M: Physiological interpretation of glucose tolerance test. In: Pfeiffer, E.F.: Handbook of diabetes mellitus. (ed. J.F. Lehmann) M\ufffdnchen 2, 947?976 (1971)","DOI":"10.1007\/978-3-642-47669-3_37"},{"key":"CR10","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1097\/00000441-196902000-00007","volume":"257","author":"H. O. Conn","year":"1969","unstructured":"Conn, H. O., Elkington, S. G.: Lack of correlation between blood glucose and ammonia concentrations. Amer. J. med. Sci. 257, 132?139 (1969)","journal-title":"Amer. J. med. Sci."},{"key":"CR11","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1016\/S0140-6736(57)90460-9","volume":"I","author":"A. M. Dawson","year":"1957","unstructured":"Dawson, A. M., De Groote, J., Rosenthal, W. S., Sherlock, S.: Blood pyruvic-acid and alpha-ketoglutaric acid levels in liver disease and hepatic coma. Lancet 1957 I, 392?396","journal-title":"Lancet"},{"key":"CR12","doi-asserted-by":"crossref","first-page":"843","DOI":"10.1016\/0002-9343(56)90098-5","volume":"21","author":"J. F. Fazekas","year":"1956","unstructured":"Fazekas, J. F., Ticktin, H. E., Ehrmantraut, W. R., Alman, R. W.: Cerebral metabolism in hepatic insufficiency. Amer. J. Med. 21, 843?849 (1956)","journal-title":"Amer. J. Med."},{"key":"CR13","doi-asserted-by":"crossref","first-page":"1027","DOI":"10.1152\/ajplegacy.1971.221.4.1027","volume":"221","author":"J. M. Feldman","year":"1971","unstructured":"Feldman, J. M., Lebowitz, H. E.: Ammonium ion, modulator of insulin secretion. Amer. J. Physiol. 221, 1027?1032 (1971)","journal-title":"Amer. J. Physiol."},{"key":"CR14","doi-asserted-by":"crossref","first-page":"910","DOI":"10.2337\/diab.15.12.910","volume":"15","author":"G. M. Grodsky","year":"1966","unstructured":"Grodsky, G. M., Benett, L. L.: Cation requirements for insulin secretion in the isolated perfused pancreas. Diabetes 15, 910?913 (1966)","journal-title":"Diabetes"},{"key":"CR15","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1042\/bj0880137","volume":"88","author":"C. N. Hales","year":"1963","unstructured":"Hales, C. N., Randle, P. J.: Immunoassay of insulin with insulin antibody precipitate. Biochem. J. 88, 137?151 (1963)","journal-title":"Biochem. J."},{"key":"CR16","doi-asserted-by":"crossref","first-page":"725","DOI":"10.1113\/jphysiol.1968.sp008433","volume":"194","author":"C. N. Hales","year":"1968","unstructured":"Hales, C. N., Milner, R. D. G.: The role of sodium and potassium in insulin secretion from rabbit pancreas. J. Physiol. (Lond.) 194, 725?743 (1968)","journal-title":"J. Physiol. (Lond.)"},{"key":"CR17","doi-asserted-by":"crossref","first-page":"1001","DOI":"10.1042\/bj1341001","volume":"134","author":"R. A. Hawkins","year":"1973","unstructured":"Hawkins, R. A., Miller, A. L., Nielsen, R. C., Veech, R. L.: The acute action of ammonia on rat brain metabolism in vivo. Biochem. J. 134, 1001?1008 (1973)","journal-title":"Biochem. J."},{"key":"CR18","first-page":"51","volume":"120","author":"W. S. Hoffmann","year":"1937","unstructured":"Hoffmann, W. S.: Rapid photoelectric method for determination of glucose in blood and urine. J. Biol. Biochem. 120, 51?55 (1937)","journal-title":"J. Biol. Biochem."},{"key":"CR19","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1042\/bj1080017","volume":"108","author":"S. L. Howell","year":"1968","unstructured":"Howell, S. L., Taylor, K. W.: Potassium ions and the secretion of insulin by islet of Langerhans incubated in vitro. Biochem. J. 108, 17?24 (1968)","journal-title":"Biochem. J."},{"key":"CR20","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1016\/0009-8981(72)90439-1","volume":"37","author":"M. Imler","year":"1972","unstructured":"Imler, M., Frick, A., Stahl, A., Peter, B., Stahl, J.: Dosage de l'ammoni\ufffdmie en discontinu et en continu par une technique de dialyse automatique. Clin. chim. Acta 37, 245?261 (1972)","journal-title":"Clin. chim. Acta"},{"key":"CR21","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1152\/ajplegacy.1951.168.1.126","volume":"168","author":"B. Mackler","year":"1952","unstructured":"Mackler, B., Lichtenstein, H., Guest, M.: Effects of ammonium chloride acidosis on glucose tolerance in dogs. Amer. J. Physiol. 168, 126?130 (1952)","journal-title":"Amer. J. Physiol."},{"key":"CR22","first-page":"52","volume":"4","author":"A. T. Maiolo","year":"1971","unstructured":"Maiolo, A. T., Bianchi Porro, G., Galli, C., Sessa, M., Polli, E. E.: Brain energy metabolism in hepatic coma. Exp. Biol. Med. 4, 52?70 (1971)","journal-title":"Exp. Biol. Med."},{"key":"CR23","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1016\/0003-9861(51)90246-9","volume":"32","author":"J. A. Muntz","year":"1951","unstructured":"Muntz, J. A., Hurwitz, J.: Effect of potassium and ammonium ions upon glycolysis catalyzed by an extract of rat brain. Arch. Biochem. Biophys. 32, 124?136 (1951)","journal-title":"Arch. Biochem. Biophys."},{"key":"CR24","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1172\/JCI105514","volume":"46","author":"D. Porte Jr.","year":"1967","unstructured":"Porte, D. Jr.: A receptor mechanism for the inhibition of insulin release by epinephrine in man. J. clin. Invest. 46, 86?94 (1967)","journal-title":"J. clin. Invest."},{"key":"CR25","doi-asserted-by":"crossref","first-page":"432","DOI":"10.1152\/ajplegacy.1971.221.2.432","volume":"221","author":"R. L. Prior","year":"1971","unstructured":"Prior, R. L., Clifford, A. J., Gibson, G. E., Visek, W. J.: Effect of insulin on glucose metabolism in hyperammonemic rats. Amer. J. Physiol. 221, 432?436 (1971)","journal-title":"Amer. J. Physiol."},{"key":"CR26","doi-asserted-by":"crossref","first-page":"1143","DOI":"10.1152\/ajplegacy.1972.223.5.1143","volume":"223","author":"R. L. Prior","year":"1972","unstructured":"Prior, R. L., Visek, W. J.: Effects of urea hydrolysis on tissue metabolite concentrations in rats. Amer. J. Physiol. 223, 1143?1149 (1972)","journal-title":"Amer. J. Physiol."},{"key":"CR27","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1152\/jappl.1956.9.3.367","volume":"9","author":"K. E. Roberts","year":"1956","unstructured":"Roberts, K. E., Thompson, F. G. III, Popell, J. W., Vanamee, P.: Respiratory alkalosis accompanying ammonium toxicity. J. appl. Physiol. 9, 367?370 (1956)","journal-title":"J. appl. Physiol."},{"key":"CR28","first-page":"659","volume-title":"In vitro procedures with radioisotopes in medicine, 1 vol.","author":"D. Rodbard","year":"1970","unstructured":"Rodbard, D., Cooper, J. A.: A model for prediction of confidence limits in radio-immunoassays and competitive protein binding assays. In: In vitro procedures with radioisotopes in medicine, 1 vol., p. 659 Vienna: Int. Atomic energy agency Edit. 1970"},{"key":"CR29","doi-asserted-by":"crossref","first-page":"838","DOI":"10.1172\/JCI105583","volume":"46","author":"S. Schenker","year":"1967","unstructured":"Schenker, S., Mc Candless, D. V., Brophy, E., Lewis, M. S.: Studies on the intracerebral toxicity of ammonia. J. clin. Invest. 46, 838?848 (1967)","journal-title":"J. clin. Invest."},{"key":"CR30","first-page":"125","volume":"22","author":"J. L. Schlienger","year":"1974","unstructured":"Schlienger, J. L., Imler, M., Stahl, J.: Etude de la tol\ufffdrance glucos\ufffde au cours du coma h\ufffdpatique. Path, et Biol. 22, 125?130 (1974)","journal-title":"Path, et Biol."},{"key":"CR31","first-page":"465","volume":"22","author":"J. L. Schlienger","year":"1974","unstructured":"Schlienger, J. L., Imler, M., Stahl, J.: Diminution de la tol\ufffdrance glucos\ufffde chez l'homme sous l'effet de la perfusion de sels d'ammonium. Path, et Biol. 22, 465?470 (1974)","journal-title":"Path, et Biol."},{"key":"CR32","first-page":"101","volume":"7","author":"J. L. Schlienger","year":"1974","unstructured":"Schlienger, J. L., Imler, M., Stahl, J.: Diminution de la tol\ufffdrance glucos\ufffde et de l'insulinos\ufffdcr\ufffdtion apr\ufffds perfusion de sels d'ammonium chez l'homme normal et chez des malades atteints de st\ufffdatose h\ufffdpatique ou de cirrhose. Biol. et Gastroent\ufffdrologie 7, 101?110 (1974)","journal-title":"Biol. et Gastroent\ufffdrologie"},{"key":"CR33","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1172\/JCI105534","volume":"46","author":"H. S. Seltzer","year":"1967","unstructured":"Seltzer, H. S., Allen, E. W., Herron, A. L., Brennan, M. T.: Insulin secretion in response to glycemic stimulus. Relation of delayed release to carbohydrate intolerance in mild diabetes mellitus. J. clin. Invest 46, 323?335 (1967)","journal-title":"J. clin. Invest"},{"key":"CR34","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1097\/00000441-196808000-00004","volume":"256","author":"B. G. Sy","year":"1968","unstructured":"Sy, B. G., Duner, G., Steigmann, F., Dubin, A.: The effect of glucose infusion on ammonia metabolism in liver failure. Amer. J. med. Sci. 256, 91?96 (1968)","journal-title":"Amer. J. med. Sci."},{"key":"CR35","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1172\/JCI103432","volume":"36","author":"W. H. J. Summerskill","year":"1957","unstructured":"Summerskill, W. H. J., Wolfe, S. J., Davidson, C. S.: The metabolism of ammonia and alphaketoacids in liver disease and hepatic coma. J. clin. Invest 36, 361?372 (1957)","journal-title":"J. clin. Invest"}],"container-title":["Diabetologia"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF00429913.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/BF00429913\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF00429913","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,4,4]],"date-time":"2020-04-04T00:18:59Z","timestamp":1585959539000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/BF00429913"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1975,10]]},"references-count":35,"journal-issue":{"issue":"5","published-print":{"date-parts":[[1975,10]]}},"alternative-id":["BF00429913"],"URL":"https:\/\/doi.org\/10.1007\/bf00429913","relation":{},"ISSN":["0012-186X","1432-0428"],"issn-type":[{"value":"0012-186X","type":"print"},{"value":"1432-0428","type":"electronic"}],"subject":[],"published":{"date-parts":[[1975,10]]}}}