{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T15:24:54Z","timestamp":1777562694890,"version":"3.51.4"},"reference-count":81,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[1972,1,1]],"date-time":"1972-01-01T00:00:00Z","timestamp":63072000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Z. Kinder-Heilk."],"published-print":{"date-parts":[[1972]]},"DOI":"10.1007\/bf00440310","type":"journal-article","created":{"date-parts":[[2004,11,11]],"date-time":"2004-11-11T15:22:05Z","timestamp":1100186525000},"page":"313-325","source":"Crossref","is-referenced-by-count":20,"title":["Multiple mucosal neuromas, pheochromocytoma, medullary carcinoma of the thyroid and marfanoid body build with muscle wasting"],"prefix":"10.1007","volume":"113","author":[{"given":"Robert J.","family":"Gorlin","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bernard L.","family":"Mirkin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"CR1","first-page":"282","volume":"43","author":"A. Wagenmann","year":"1922","unstructured":"Wagenmann, A.: Multiple Neurome des Auges und der Zunge. Ber. dtsch. ophthal. Ges. 43, 282?285 (1922).","journal-title":"Ber. dtsch. ophthal. Ges."},{"key":"CR2","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1007\/BF01963398","volume":"240","author":"C. Froboese","year":"1922","unstructured":"Froboese, C.: Das aus markhaltigen Nervenfasern bestehende, ganglienzellenlose, echte Neurom in Rankenform ? Zugleich ein Beitrag zu den nerv\ufffdsen Geschw\ufffdlsten der Zunge und des Augenlides. Virchows Arch. path. Anat. 240, 312?327 (1922). (Same as Wagenmann [1]).","journal-title":"Virchows Arch. path. Anat."},{"key":"CR3","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1002\/path.1700910109","volume":"91","author":"E. D. Williams","year":"1966","unstructured":"Williams, E. D., Pollock, D. J.: Multiple mucosal neuromata with endocrine tumours ? A syndrome allied to von Recklinghausen's disease. J. Path. Bact. 91, 71?80 (1966).","journal-title":"J. Path. Bact."},{"key":"CR4","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1002\/1097-0142(196808)22:2<293::AID-CNCR2820220206>3.0.CO;2-R","volume":"22","author":"R. J. Gorlin","year":"1968","unstructured":"Gorlin, R. J., Sedano H. O., Vickers, R. A., ?ervenka, J.: Multiple mucosal neuroma, pheochromocytoma and medullary carcinoma of the thyroid ? A syndrome. Cancer (Philad.) 22, 293?299 (1968).","journal-title":"Cancer (Philad.)"},{"key":"CR5","first-page":"69","volume":"7","author":"R. J. Gorlin","year":"1971","unstructured":"Gorlin, R. J., Vickers, R. A.: Multiple mucosal neuromas, pheochromocytoma. Medullary carcinoma of the thyroid and marfanoid body build with muscle wasting: Reexamination of a syndrome of neural crest malmigration. Birth Def. Orig. Art. Ser. 7, 69?72 (1971).","journal-title":"Birth Def. Orig. Art. Ser."},{"key":"CR6","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1056\/NEJM196807042790101","volume":"279","author":"R. N. Schimke","year":"1968","unstructured":"Schimke, R. N., Hartmann, W. J., Prout, T. E., Rimoin, D. L.: Syndrome of bilateral pheochromocytoma, medullary thyroid carcinoma and multiple neuromas. A possible regulatory defect in the differentiation of chromaffin tissues. New Engl. J. Med. 279, 1?7 (1968).","journal-title":"New Engl. J. Med."},{"key":"CR7","first-page":"561","volume":"27","author":"M. Levy","year":"1970","unstructured":"Levy, M., Habib, R., Lyon, G., Schweisguth, O., Lemerle, J., Roger, P.: Neuromatose et epithelioma a stroma amyloide de la thyroide chez l'enfant. Arch. fran\ufffd. P\ufffddiat. 27, 561?583 (1970).","journal-title":"Arch. fran\ufffd. P\ufffddiat."},{"key":"CR8","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1148\/101.1.93","volume":"101","author":"T. E. Anderson","year":"1971","unstructured":"Anderson, T. E., Spackman, T. J., Schwartz, S. S.: Roentgen findings in intestinal ganglioneuromatosis. Its association with medullary thyroid carcinoma and pheochromocytoma. Radiology 101, 93?96 (1971).","journal-title":"Radiology"},{"key":"CR9","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1016\/0030-4220(71)90075-2","volume":"31","author":"A. Bartlett","year":"1971","unstructured":"Bartlett, A., Bean, R. C., Mandelstam, P.: A neuropolyendocrine syndrome. Mucosal neuromas, pheochromocytoma, and medullary thyroid carcinoma. Oral Surg. 31, 206?220 (1971).","journal-title":"Oral Surg."},{"key":"CR10","doi-asserted-by":"crossref","first-page":"963","DOI":"10.1056\/NEJM197104292841709","volume":"284","author":"J. L. Baum","year":"1971","unstructured":"Baum, J. L.: Abnormal intradermal reaction in the syndrome of pheochromocytoma, medullary carcinoma of the thyroid gland and multiple mucosal neuromas. New Engl. J. Med. 284, 963?964 (1971).","journal-title":"New Engl. J. Med."},{"key":"CR11","first-page":"613","volume":"85","author":"A. Bazex","year":"1958","unstructured":"Bazex, A., Dupr\ufffd A.: Neuromas myeliniques muqueux \ufffd localisation centrofaciale et laryng\ufffde. Neuromes des l\ufffdvres, de la langue, des paupi\ufffdres, des narines, du larynx (Entit\ufffd nouvelle?). Ann. Derm. Syph. (Paris) 85, 613?641 (1958).","journal-title":"Ann. Derm. Syph. (Paris)"},{"key":"CR12","first-page":"189","volume":"52","author":"A. E. Braley","year":"1954","unstructured":"Braley, A. E.: Medullated corneal nerves and plexiform neuroma associated with pheochromocytoma. Trans. Amer ophthal. Soc. 52, 189?197 (1954).","journal-title":"Trans. Amer ophthal. Soc."},{"key":"CR13","doi-asserted-by":"crossref","first-page":"1150","DOI":"10.1016\/0030-4220(54)90307-2","volume":"7","author":"K. W. Bruce","year":"1954","unstructured":"Bruce, K. W.: Solitary neurofibroma (neurilemmoma, schwannoma) of the oral cavity. Oral Surg. 7, 1150?1159 (1954). (Same as Reynolds [28]).","journal-title":"Oral Surg."},{"key":"CR14","first-page":"257","volume":"19","author":"L. Calmettes","year":"1959","unstructured":"Calmettes, L., Bazex, A., Deodati, F., Dupr\ufffd A., Bec P.: Manifestations oculopalp\ufffdbrales des neuromes my\ufffdliniques muqueux. Arch. Ophthal. (Paris) 19, 257?269 (1959).","journal-title":"Arch. Ophthal. (Paris)"},{"key":"CR15","first-page":"103","volume":"68","author":"P. Cernea","year":"1967","unstructured":"Cernea, P., Cr\ufffdpy, C., Kuffer, R., Mascaro, J. M.: Neuromes my\ufffdliniques muqueux de la cavit\ufffd buccale. Rev. Stomat. (Paris) 68, 103?116 (1967).","journal-title":"Rev. Stomat. (Paris)"},{"key":"CR16","doi-asserted-by":"crossref","unstructured":"Cunliffe, W. J., Black, M. M., Hall, R., Johnstone I., Hodgson, P., Shuster, S.: A calcitonin-secretory thyroid carcinoma. Lancet 1968 II, 63?66.","DOI":"10.1016\/S0140-6736(68)90352-8"},{"key":"CR17","first-page":"1235","volume":"5","author":"J. Grandbois","year":"1969","unstructured":"Grandbois, J., Tchou, P. K.: Mucous membrane manifestations of neurofibromatosis with malignant tumors of endocrine glands. Cutis 5, 1235?1239 (1969).","journal-title":"Cutis"},{"key":"CR18","first-page":"644","volume":"156","author":"H. Jacobi","year":"1970","unstructured":"Jacobi, H., Kleine-Natrop, H. E.: Beitrag zum ?Syndrom der angeborenen fibrill\ufffdren Neurome?. Derm. Mschr. 156, 644?652 (1970).","journal-title":"Derm. Mschr."},{"key":"CR19","first-page":"158","volume":"16","author":"J. M. Jorge","year":"1927","unstructured":"Jorge, J. M., Brachetto-Brian, D.: Contribution \ufffd l'\ufffdtude des formes incompl\ufffdtes de la maladie de Recklinghausen. Bull. Ass. fran\ufffd. Cancer 16, 158?170 (1927).","journal-title":"Bull. Ass. fran\ufffd. Cancer"},{"key":"CR20","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1016\/S0002-9394(40)92522-3","volume":"23","author":"M. P. Koke","year":"1940","unstructured":"Koke, M. P., Braley, A. E.: Bilateral plexiform neuromata of the conjunctiva and medullated corneal nerves. Amer. J. Ophthal. 23, 179?182 (1940). (Same as Van Epps et al. [36]).","journal-title":"Amer. J. Ophthal."},{"key":"CR21","doi-asserted-by":"crossref","unstructured":"Ljungberg, O., Cederquist, E., Von Studnits, W.: Medullary thyroid carcinoma and pheochromocytoma ? A familial chromaffinomatosis. Brit. med. J. 1967 I, 279?281.","DOI":"10.1136\/bmj.1.5535.279"},{"key":"CR22","first-page":"184","volume":"89","author":"F. Loos","year":"1932","unstructured":"Loos, F.: \ufffdber doppelseitige Neurofibromatosis der Lider, Konjunctiva und Kornea, der Lippen und der Zunge. Klin. Mbl. Augenheilk. 89, 184?189 (1932).","journal-title":"Klin. Mbl. Augenheilk."},{"key":"CR23","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1007\/BF00501521","volume":"231","author":"R. Michalowski","year":"1966","unstructured":"Michalowski, R.: Multiple fibrill\ufffdre Neurome der Augenlider, Lippen und Zunge mit Genitalhypoplasie und Gelenkanomalien, Beitrag zur Kenntnis der zentrofazialen Neuromatosis. Arch. klin. exp. Derm. 231, 20?27 (1966).","journal-title":"Arch. klin. exp. Derm."},{"key":"CR24","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1016\/S0016-5085(65)80117-2","volume":"48","author":"J. E. Mielke","year":"1965","unstructured":"Mielke, J. E., Becker, K. L., Gross, J. B.: Diverticulitis of the colon in a young man with Marfan's syndrome ? Associated with carcinoma of the thyroid gland and neurofibromas of the tongue and lips. Gastroenterology 48, 379?382 (1965).","journal-title":"Gastroenterology"},{"key":"CR25","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1136\/jmg.7.4.374","volume":"7","author":"H. Nankin","year":"1970","unstructured":"Nankin, H., Hydovitz, J., Sapira, J.: Normal chromosomes in mucosal neuroma variant of medullary thyroid carcinoma syndrome. J. med. Genet. 7, 374?378 (1970).","journal-title":"J. med. Genet."},{"key":"CR26","first-page":"553","volume":"4","author":"T. Normann","year":"1969","unstructured":"Normann, T., Otnes, B.: Intestinal ganglioneuromatosis. Diarrhea and medullary thyroid carcinoma. Scand. J. Gastroent. 4, 553?559 (1969).","journal-title":"Scand. J. Gastroent."},{"key":"CR27","doi-asserted-by":"crossref","first-page":"599","DOI":"10.1016\/0030-4220(53)90163-7","volume":"6","author":"H. M. Rappaport","year":"1953","unstructured":"Rappaport, H. M.: Neurofibromatosis of the oral cavity. Oral Surg. 6, 599?604 (1953).","journal-title":"Oral Surg."},{"key":"CR28","unstructured":"Reynolds, D. R.: Neurogenic tumors of the tongue. M.S. Thesis, Univ. Minnesota 1962."},{"key":"CR29","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1016\/0026-0495(66)90114-4","volume":"15","author":"R. D. Ruppert","year":"1966","unstructured":"Ruppert, R. D., Buerger, L. F., Chang, W. W. L.: Pheochromocytoma, neurofibromatosis and thyroid carcinoma. Metabolism 15, 537?541 (1966).","journal-title":"Metabolism"},{"key":"CR30","first-page":"322","volume-title":"Pathology of tumors of the nervous system","author":"D. S. Russell","year":"1971","unstructured":"Russell, D. S., Rubinstein, L. J.: Pathology of tumors of the nervous system, 3rd ed., pp. 322, 328?329. London: Arnold 1971. (Same as Williams and Pollock [3]?Case 2).","edition":"3rd ed."},{"key":"CR31","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1001\/archpedi.1957.04030030079012","volume":"94","author":"E. Shocket","year":"1957","unstructured":"Shocket, E., Teloh, H. A.: Aganglionic megacolon, pheochromocytoma, megaloureter and neurofibroma. Co-occurrence of several neural abnormalities. Amer. J. Dis. Child. 94, 185?191 (1957). (Same as Texter [34]).","journal-title":"Amer. J. Dis. Child."},{"key":"CR32","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1016\/0030-4220(65)90296-3","volume":"19","author":"H. E. Simpson","year":"1965","unstructured":"Simpson, H. E.: Oral neurofibromatosis with differentiation of sensory end organs. Oral Surg. 19, 228?233 (1965).","journal-title":"Oral Surg."},{"key":"CR33","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1177\/000992287101000208","volume":"10","author":"G. S. Sturtz","year":"1971","unstructured":"Sturtz, G. S., Brown, R. B.: Medullary carcinoma of the thyroid. Bumpy lip syndrome. Clin. Pediat. 10, 81?85 (1971).","journal-title":"Clin. Pediat."},{"key":"CR34","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1007\/BF02233388","volume":"1","author":"E. C. Texter Jr.","year":"1956","unstructured":"Texter, E. C., Jr.: Hirschsprung's disease. Amer. J. dig. Dis. 1, 35?46 (1956).","journal-title":"Amer. J. dig. Dis."},{"key":"CR35","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1007\/BF00488381","volume":"218","author":"W. Thies","year":"1964","unstructured":"Thies, W.: Multiple echte fibrill\ufffdre Neurome (Rankenneurome) der Haut und Schleimhaut. Arch. klin. exp. Derm. 218, 561?573 (1964).","journal-title":"Arch. klin. exp. Derm."},{"key":"CR36","doi-asserted-by":"crossref","first-page":"1123","DOI":"10.1001\/archinte.1940.00190120040004","volume":"65","author":"E. F. Epps Van","year":"1940","unstructured":"Van Epps, E. F., Hyndman, O. R., Greene, J. A.: Clinical manifestations of paroxysmal hypertension associated with pheochromocytoma of adrenal. Arch. intern. Med. 65, 1123?1129 (1940).","journal-title":"Arch. intern. Med."},{"key":"CR37","first-page":"555","volume":"38","author":"T. J. Duffy","year":"1962","unstructured":"Duffy, T. J., Erickson, E. C., Jordan, G. L., Bennett, H. D.: Megacolon and bilateral pheochromocytoma. Amer. J. Gastroent. 38, 555?563 (1962).","journal-title":"Amer. J. Gastroent."},{"key":"CR38","first-page":"761","volume":"56","author":"J. Bernier","year":"1967","unstructured":"Bernier, J., Savoie, J., Garnier, H., Cattan, D., Bouvry, M., Ramerud, J., Bognel, C., Prost, A.: Deux cas de diarrhee cancer medullaire du corps thyroide. Arch. fran\ufffd. Mal. Dig. 56, 761?772 (1967).","journal-title":"Arch. fran\ufffd. Mal. Dig."},{"key":"CR39","doi-asserted-by":"crossref","first-page":"1075","DOI":"10.1016\/0030-4220(63)90223-8","volume":"16","author":"G. Shklar","year":"1963","unstructured":"Shklar, G., Meyer, I.: Neurogenic tumors of the mouth and jaws. Oral Surg. 16, 1075?1093 (1963).","journal-title":"Oral Surg."},{"key":"CR40","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1001\/archneur.1962.00450210070008","volume":"6","author":"I. Gleason","year":"1962","unstructured":"Gleason, I., Beauchemin, J., Bursk, A.: Polypoid ganglioneuromatosis of the large bowel. Arch. Neurol. 6, 242?247 (1962).","journal-title":"Arch. Neurol."},{"key":"CR41","first-page":"479","volume":"24","author":"P. Chibon","year":"1970","unstructured":"Chibon, P.: Capacit\ufffd de r\ufffdgulation des exc\ufffddents dans la cr\ufffdte neurale d'Amphibien. J. Embryol. exp. Morph. 24, 479?496 (1970).","journal-title":"J. Embryol. exp. Morph."},{"key":"CR42","first-page":"2857","volume":"270","author":"N. Dourin Le","year":"1970","unstructured":"Le Dourin, N., Le Li\ufffdvre, C.: Demonstration de l'origine neurale des cellules \ufffd calcitonine du corps ultimobrancial chez l'embryon de Poulet. C. R. Acad. Sci. (Paris) Ser. D. 270, 2857?2860 (1970).","journal-title":"C. R. Acad. Sci. (Paris) Ser. D."},{"key":"CR43","unstructured":"Gorlin, R. J., Winkelmann, R.: Unpublished data, 1970."},{"key":"CR44","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1097\/00000658-196709000-00008","volume":"166","author":"M. A. Block","year":"1967","unstructured":"Block, M. A., Horn, R. C., Jr., Miller, J. M., Barrett, J. L., Brush, B. E.: Familial medullary carcinoma of the thyroid. Ann. Surg. 166, 403?415 (1967).","journal-title":"Ann. Surg."},{"key":"CR45","first-page":"306","volume":"85","author":"H. Braunstein","year":"1968","unstructured":"Braunstein, H., Stephens, C. L., Gibson, R. L.: Secretory granules in medullary carcinoma of the thyroid. Arch. Path. 85, 306?313 (1968).","journal-title":"Arch. Path."},{"key":"CR46","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1001\/archinte.1969.00300140069015","volume":"123","author":"W. J. Dube","year":"1969","unstructured":"Dube, W. J., Bell, G. O., Aliopoulios, M. A.: Thyrocalcitonin activity in metastatic medullary thyroid carcinoma. Further evidence for its parafollicular cell origin. Arch. intern. Med. 123, 423?427 (1969).","journal-title":"Arch. intern. Med."},{"key":"CR47","doi-asserted-by":"crossref","first-page":"406","DOI":"10.1002\/1097-0142(196803)21:3<406::AID-CNCR2820210310>3.0.CO;2-6","volume":"21","author":"J. S. Meyer","year":"1968","unstructured":"Meyer, J. S.: Fine structure of two amyloid-forming medullary carcinoma of the thyroid. Cancer 21, 406?425 (1968).","journal-title":"Cancer"},{"key":"CR48","doi-asserted-by":"crossref","first-page":"706","DOI":"10.1002\/1097-0142(1967)20:5<706::AID-CNCR2820200523>3.0.CO;2-M","volume":"20","author":"M. L. Ibanez","year":"1967","unstructured":"Ibanez, M. L., Cole, V. M., Russel, W. O., Clark, R. L.: Solid carcinoma of the thyroid gland-analysis of 53 cases. Cancer (Philad.) 20, 706?723 (1967).","journal-title":"Cancer (Philad.)"},{"key":"CR49","doi-asserted-by":"crossref","first-page":"512","DOI":"10.1093\/ajcp\/49.4.512","volume":"49","author":"A. Gonzalez-Licea","year":"1968","unstructured":"Gonzalez-Licea, A., Hartmann, W. H., Yardley, J. H.: Medullary carcinoma of the thyroid. Ultrastructural evidence of its origin from the parafollicular cell and its possible relation to carcinoid tumors. Amer. J. clin. Path. 49, 512?520 (1968).","journal-title":"Amer. J. clin. Path."},{"key":"CR50","doi-asserted-by":"crossref","first-page":"1199","DOI":"10.1210\/jcem-28-8-1199","volume":"28","author":"G. F. Donahower","year":"1968","unstructured":"Donahower, G. F., Schumacher, O. P., Hazard, J. B.: Medullary carcinoma of the thyroid ? A cause of Cushing's syndrome, Report of 2 cases. J. clin. Endocr. 28, 1199?1204 (1968).","journal-title":"J. clin. Endocr."},{"key":"CR51","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1136\/jcp.21.2.129","volume":"21","author":"E. D. Williams","year":"1968","unstructured":"Williams, E. D., Morales, A. M., Horn, R. C.: Thyroid carcinoma and Cushing's syndrome. J. clin. Path. 21, 129?135 (1968).","journal-title":"J. clin. Path."},{"key":"CR52","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1056\/NEJM196507292730504","volume":"273","author":"C. G. Moertel","year":"1965","unstructured":"Moertel, C. G., Beahrs, O. H., Wollner, L. B., Tyce, G. M.: ?Malignant carcinoid syndrome? associated with noncarcinoid tumors. New Engl. J. Med. 273, 244?248 (1965).","journal-title":"New Engl. J. Med."},{"key":"CR53","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/j.1699-0463.1968.tb03449.x","volume":"74","author":"B. falck","year":"1968","unstructured":"falck, B., Ljungberg, O., Rosengren, E.: On the occurrence of monoamines and related substances in familial medullary thyroid carcinoma with phaeochromocytoma. Acta path. microbiol. scand. 74, 1?10 (1968).","journal-title":"Acta path. microbiol. scand."},{"key":"CR54","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1136\/jcp.19.2.103","volume":"19","author":"E. D. Williams","year":"1966","unstructured":"Williams, E. D., Brown, C. L., Donaich, I.: Pathological and clinical findings in a series of 67 cases of medullary carcinoma of the thyroid. J. clin. Path. 19, 103?113 (1966)","journal-title":"J. clin. Path."},{"key":"CR55","doi-asserted-by":"crossref","unstructured":"Williams, E. D., Karim, S. M. M., Sandler, M.: Prostaglandin secretion by medullary carcinoma of the thyroid. A possible cause of the associated diarrhea. Lancet 1968 I, 22?23.","DOI":"10.1016\/S0140-6736(68)90010-X"},{"key":"CR56","doi-asserted-by":"crossref","unstructured":"Sandler, M., Karim, S. M. M., Williams, E. D.: Prostaglandins in aminepeptide-secreting tumours. Lancet 1968 II, 1053?1054.","DOI":"10.1016\/S0140-6736(68)91528-6"},{"key":"CR57","doi-asserted-by":"crossref","unstructured":"Baylin, S. B., Beaven, M. A., Keiser, H. R., Tashjian, A. H., Jr., Melvin, K. E. W.: Serum histaminase and calcitonin levels in medullary carcinoma of the thyroid. Lancet 1972 I, 455?458.","DOI":"10.1016\/S0140-6736(72)90120-1"},{"key":"CR58","doi-asserted-by":"crossref","first-page":"983","DOI":"10.1056\/NEJM197102042840520","volume":"284","author":"R. J. Gorlin","year":"1971","unstructured":"Gorlin, R. J.: Skin test for medullary thyroid carcinoma. New Engl. J. Med. 284, 983?984 (1971).","journal-title":"New Engl. J. Med."},{"key":"CR59","first-page":"621","volume":"78","author":"O. Ljungberg","year":"1970","unstructured":"Ljungberg, O.: Two histochemically different human parafollicular cells. Acta path. microbiol. scand. Sect. A. 78, 621?624 (1970).","journal-title":"Acta path. microbiol. scand. Sect. A."},{"key":"CR60","doi-asserted-by":"crossref","first-page":"1147","DOI":"10.1056\/NEJM195512292532603","volume":"253","author":"O. Swenson","year":"1955","unstructured":"Swenson, O., Fisher, J. H.: The relations of megacolon and megaloureter, New Engl. J. Med. 253, 1147?1150 (1955).","journal-title":"New Engl. J. Med."},{"key":"CR61","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1212\/WNL.19.5.455","volume":"19","author":"D. W. Nibbelink","year":"1969","unstructured":"Nibbelink, D. W., Peters, B. H., McCormick, W. F.: On the association of pheochromocytoma and cerebellar hemangioblastoma. Neurology (Minneap.) 19, 455?460 (1969).","journal-title":"Neurology (Minneap.)"},{"key":"CR62","doi-asserted-by":"crossref","first-page":"783","DOI":"10.1136\/gut.12.10.783","volume":"12","author":"A. G. E. Pearse","year":"1971","unstructured":"Pearse, A. G. E., Polak, J. M.: Neural crest origin of the endocrine polypeptide (APUD) cells of the gastrointestinal tract and pancreas. Gut 12, 783?788 (1971).","journal-title":"Gut"},{"key":"CR63","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1002\/ar.1091560204","volume":"156","author":"M. C. Johnston","year":"1966","unstructured":"Johnston, M. C.: A radioautographic study of the migration and fate of cranial neural crest cells in the chick embryo. Anat. Rec. 156, 143?155 (1966).","journal-title":"Anat. Rec."},{"key":"CR64","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1097\/00005792-196809000-00001","volume":"47","author":"A. L. Steiner","year":"1968","unstructured":"Steiner, A. L., Goodman, A. D., Powers, S. E.: Study of a kindred with pheochromocytoma, medullary thyroid carcinoma, hyperparathyroidism and Cushing's disease with multiple endocrine neoplasia, type 2. Medicine (Baltimore) 47, 371?410 (1968).","journal-title":"Medicine (Baltimore)"},{"key":"CR65","doi-asserted-by":"crossref","first-page":"53","DOI":"10.7326\/0003-4819-76-1-53","volume":"76","author":"N. Snyder","year":"1972","unstructured":"Snyder, N., Scurry, M. T., Deiss, W. P., Jr.: Five families with multiple endocrine adenomatosis. Ann. intern. Med. 76, 53?58 (1972).","journal-title":"Ann. intern. Med."},{"key":"CR66","doi-asserted-by":"crossref","first-page":"1305","DOI":"10.7326\/0003-4819-68-6-1305","volume":"68","author":"G. Sarosi","year":"1968","unstructured":"Sarosi, G., Doe, R. P.: Familial occurrence of parathyroid adenomas. pheochromocytoma, and medullary carcinoma of the thyroid with amyloid stroma (Sipple's syndrome). Ann. intern. Med. 68, 1305?1309 (1968).","journal-title":"Ann. intern. Med."},{"key":"CR67","doi-asserted-by":"crossref","first-page":"608","DOI":"10.1016\/0002-9343(69)90190-9","volume":"47","author":"R. Aach","year":"1969","unstructured":"Aach, R., Kissane, J.: Multiple endocrine adenomatosis. Amer. J. Med. 47, 608?618 (1969).","journal-title":"Amer. J. Med."},{"key":"CR68","doi-asserted-by":"crossref","first-page":"1115","DOI":"10.1016\/S0039-6109(16)38333-5","volume":"47","author":"E. H. Ellison","year":"1967","unstructured":"Ellison, E. H., Wilson, S. D.: The Zollinger-Ellison syndrome updated. Surg. Clin. N. Amer. 47, 1115?1124 (1967).","journal-title":"Surg. Clin. N. Amer."},{"key":"CR69","doi-asserted-by":"crossref","first-page":"807","DOI":"10.1016\/0002-9610(66)90130-9","volume":"112","author":"P. M. Guida","year":"1966","unstructured":"Guida, P. M., Todd, J. E., Moore, S. W., Beal, J. M.: Zollinger-Ellison syndrome with interesting variations. Report of twelve cases including one of carcinoid of the duodenum. Amer. J. Surg. 112, 807?817 (1966).","journal-title":"Amer. J. Surg."},{"key":"CR70","doi-asserted-by":"crossref","first-page":"608","DOI":"10.1016\/0002-9343(69)90190-9","volume":"47","author":"D. Kipnis","year":"1969","unstructured":"Kipnis, D.: Multiple endocrine adenomatosis. Amer. J. Med. 47, 608?618 (1969).","journal-title":"Amer. J. Med."},{"key":"CR71","doi-asserted-by":"crossref","first-page":"695","DOI":"10.1016\/0002-9610(68)90104-9","volume":"115","author":"D. J. Lulu","year":"1968","unstructured":"Lulu, D. J., Corcoran, T. E., Andre, M.: Familial endocrine adenomatosis with associated Zollinger-Ellison syndrome. Wermer's syndrome. Amer. J. Surg. 115, 695?701 (1968).","journal-title":"Amer. J. Surg."},{"key":"CR72","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1016\/0002-9610(68)90507-2","volume":"116","author":"L. Way","year":"1968","unstructured":"Way, L., Goldman, L., Dunphy, J. E.: Zollinger-Ellison syndrome. An analysis of twenty-five cases. Amer. J. Surg. 116, 293?304 (1968).","journal-title":"Amer. J. Surg."},{"key":"CR73","first-page":"146","volume":"68","author":"E. L. Kaplan","year":"1970","unstructured":"Kaplan, E. L., Arnaud, C. D., Hill, B. J., Peskin, G. W.: Adrenal medullary calcitonin-like factor: A key to multiple endocrine neoplasia, type 2. Surgery 68, 146?149 (1970).","journal-title":"Surgery"},{"key":"CR74","doi-asserted-by":"crossref","first-page":"731","DOI":"10.1001\/archinte.1969.00300220083016","volume":"124","author":"W. V. R. Vieweg","year":"1969","unstructured":"Vieweg, W. V. R., Graber, A. L., Cerchio, G. M.: Pancreatic islet cell carcinoma with hyperinsulinism and probably, ectopic ACTH-MSH secretion. Arch. intern. Med. 124, 731?735 (1969).","journal-title":"Arch. intern. Med."},{"key":"CR75","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1056\/NEJM196508052730602","volume":"273","author":"D. H. Law","year":"1965","unstructured":"Law, D. H., Liddle, G. W., Scott, H. W., Jr., Tauber, S. D.: Ectopic production of multiple hormones (AXRH, MSH and gastrin) by a single malignant tumor. New Engl. J. Med. 273, 292?295 (1965).","journal-title":"New Engl. J. Med."},{"key":"CR76","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1136\/pgmj.46.533.159","volume":"46","author":"T. N. Appleyard","year":"1970","unstructured":"Appleyard, T. N., Losowsky, M. S.: A pancreatic tumor with carcinoid syndrome and hypoglycaemia. Postgrad. med. J. 46, 159?171 (1970).","journal-title":"Postgrad. med. J."},{"key":"CR77","doi-asserted-by":"crossref","first-page":"835","DOI":"10.1136\/gut.12.10.835","volume":"12","author":"V. Marks","year":"1971","unstructured":"Marks, V.: Diagnosis of insulinoma. Gut 12, 835?843 (1971).","journal-title":"Gut"},{"key":"CR78","doi-asserted-by":"crossref","first-page":"274","DOI":"10.1002\/1097-0142(196808)22:2<274::AID-CNCR2820220204>3.0.CO;2-W","volume":"22","author":"L. W. O'Neal","year":"1968","unstructured":"O'Neal, L. W., Kipnis, D. M., Luse, S. A., Lacy, P. E., Jarett, L.: Secretion of various endocrine substances by ACTH-secreting tumors?gastrin, melanotropin, norepinephrine, serotonin, parathormone, vasopressin, glucagon. Cancer 22, 274?286 (1968).","journal-title":"Cancer"},{"key":"CR79","doi-asserted-by":"crossref","first-page":"274","DOI":"10.1002\/1097-0142(196808)22:2<274::AID-CNCR2820220204>3.0.CO;2-W","volume":"22","author":"J. G. Azzopardi","year":"1968","unstructured":"Azzopardi, J. G., Williams, E. D.: pathology of ?nonendocrine? tumors associated with Cushing's syndrome. Cancer. 22, 274?286 (1968).","journal-title":"Cancer"},{"key":"CR80","first-page":"899","volume":"52","author":"W. Peterson","year":"1969","unstructured":"Peterson, W., Gorlin, R. J.: Thioflavine-T reactivity in basal cell carcinomas and ameloblastomas. Minn. Med. 52, 899?901 (1969).","journal-title":"Minn. Med."},{"key":"CR81","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1098\/rspb.1968.0025","volume":"170","author":"A. G. E. Pearse","year":"1968","unstructured":"Pearse, A. G. E.: Common cytochemical and ultrastructural characteristics of cells producing polypeptide hormones (the APUD series) and then relevance to thyroid and ultimobranchial cells and calcitonin. Proc. roy. Soc. B. 170, 71?80 (1968).","journal-title":"Proc. roy. Soc. B."}],"container-title":["Zeitschrift f\ufffdr Kinderheilkunde"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF00440310.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/BF00440310\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF00440310","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,15]],"date-time":"2024-01-15T07:09:59Z","timestamp":1705302599000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/BF00440310"}},"subtitle":["Syndrome of hyperplasia and neoplasia of neural crest derivatives?an unitarian concept"],"short-title":[],"issued":{"date-parts":[[1972]]},"references-count":81,"journal-issue":{"issue":"4","published-print":{"date-parts":[[1972]]}},"alternative-id":["BF00440310"],"URL":"https:\/\/doi.org\/10.1007\/bf00440310","relation":{},"ISSN":["0340-6199","1432-1076"],"issn-type":[{"value":"0340-6199","type":"print"},{"value":"1432-1076","type":"electronic"}],"subject":[],"published":{"date-parts":[[1972]]}}}