{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,27]],"date-time":"2026-06-27T08:35:06Z","timestamp":1782549306281,"version":"3.54.5"},"reference-count":22,"publisher":"Springer Science and Business Media LLC","issue":"7","license":[{"start":{"date-parts":[[1989,6,1]],"date-time":"1989-06-01T00:00:00Z","timestamp":612662400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Eur J Pediatr"],"published-print":{"date-parts":[[1989,6]]},"DOI":"10.1007\/bf00441533","type":"journal-article","created":{"date-parts":[[2004,11,12]],"date-time":"2004-11-12T02:37:47Z","timestamp":1100227067000},"page":"679-681","source":"Crossref","is-referenced-by-count":20,"title":["Concentrations of ceftazidime, tobramycin and ampicillin in the cerebrospinal fluid of newborn infants"],"prefix":"10.1007","volume":"148","author":[{"given":"I.","family":"Tessin","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B.","family":"Trollfors","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K.","family":"Thiringer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Z.","family":"Th\ufffdrn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.","family":"Larsson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"CR1","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1159\/000457041","volume":"8","author":"JL Blumer","year":"1985","unstructured":"Blumer JL, Aronoff SC, Myers CM, O'Brien CA, Klinger JD, Reed MD (1985) Pharmacokinetics and cerebrospinal fluid penetration of ceftazidime in children with meningitis. Dev Pharmacol Ther 8:219?231","journal-title":"Dev Pharmacol Ther"},{"key":"CR2","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1128\/AAC.26.1.115","volume":"26","author":"IW Fong","year":"1984","unstructured":"Fong IW, Tomkins KB (1984) Penetration of ceftazidime into the cerebrospinal fluid with and without evidence of meningeal inflammation. Antimicrob Agents Chemother 26:115?116","journal-title":"Antimicrob Agents Chemother"},{"key":"CR3","first-page":"545","volume":"123","author":"JM Geering","year":"1975","unstructured":"Geering JM, Just M (1975) Die Blut-Liquor Verteilung von Ampicillin bei Kindern mit und ohne ser\u00f6se Meningitis. Monatsschr Kinderheilkd 123:545?547","journal-title":"Monatsschr Kinderheilkd"},{"key":"CR4","doi-asserted-by":"crossref","first-page":"416","DOI":"10.1097\/00006454-198607000-00007","volume":"5","author":"D Hatch","year":"1986","unstructured":"Hatch D, Overtyrf GD, Kovacs A, Forthal D, Leong C (1986) Treatment of bacterial meningitis with ceftazidime. Pediatr Infect Dis 5:416?420","journal-title":"Pediatr Infect Dis"},{"key":"CR5","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1007\/BF00561138","volume":"4","author":"B Jalling","year":"1972","unstructured":"Jalling B, Malmborg AS, Bor\u00e9us LO (1972) Evaluation of a micromethod for determination of antibiotic concentration in plasma. Eur J Clin Pharmacol 4:150?157","journal-title":"Eur J Clin Pharmacol"},{"issue":"Suppl B","key":"CR6","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1093\/jac\/8.suppl_B.187","volume":"8","author":"RN Jones","year":"1981","unstructured":"Jones RN, Barry AL, Thornsberry C, Gerlach EH, Fuchs PC, Gavan TL, Sommers HM (1981) Ceftazidime, a pseudomonasactive cephalosporin: in vitro antimicrobial evaluation including recommendations for disc diffusion susceptibility tests. J Antimicrob Chemother 8 [Suppl B]:187?211","journal-title":"J Antimicrob Chemother"},{"issue":"1","key":"CR7","doi-asserted-by":"crossref","first-page":"1215","DOI":"10.1056\/NEJM197512112932401","volume":"293","author":"AB Kaiser","year":"1975","unstructured":"Kaiser AB, McSee ZA (1975) Aminoglycoside therapy of Gramnegative bacillary meningitis. N Engl J Med 293:1 1215?1220","journal-title":"N Engl J Med"},{"key":"CR8","doi-asserted-by":"crossref","first-page":"360","DOI":"10.1136\/adc.60.4.360","volume":"60","author":"DC Low","year":"1985","unstructured":"Low DC, Bisseden JG, Wise R (1985) Ceftazidime in neonatal infections. Arch Dis Child 60:360?364","journal-title":"Arch Dis Child"},{"key":"CR9","first-page":"547","volume":"123","author":"GH McCracken","year":"1972","unstructured":"McCracken GH (1972) The rate of bacteriologic response to anti-microbial therapy in neonatal meningitis. Am J Dis Child 123: 547?553","journal-title":"Am J Dis Child"},{"key":"CR10","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1128\/AAC.24.1.126","volume":"24","author":"J Modai","year":"1983","unstructured":"Modai J, Vittecoq D, Decazes JH, Wolff M, Meulemans A (1983) Penetration of ceftazidime into cerebrospinal fluid of patients with bacterial meningitis. Antimicrob Agents Chemother 24:126?128","journal-title":"Antimicrob Agents Chemother"},{"key":"CR11","doi-asserted-by":"crossref","first-page":"534","DOI":"10.1016\/S0022-3476(72)80182-3","volume":"81","author":"RS Moellering","year":"1972","unstructured":"Moellering RS, Fisher EG (1972) Relationship of intraventricular gentamicin levels to cure of meningitis. J Pediatr 81:534?537","journal-title":"J Pediatr"},{"key":"CR12","doi-asserted-by":"crossref","first-page":"897","DOI":"10.1136\/adc.58.11.897","volume":"58","author":"A Mullhall","year":"1983","unstructured":"Mullhall A, Louvois J de, Hurley R (1983) Incidence of potentially toxic concentration of gntamicin in neonates. Arch Dis Child 58:897?900","journal-title":"Arch Dis Child"},{"issue":"Suppl B","key":"CR13","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1093\/jac\/8.suppl_B.131","volume":"8","author":"HC Neu","year":"1981","unstructured":"Neu HC (1981) In vitro activity of ceftazidime, a betalactamase stable cephalosporin. J Antimicrob Chemother 8 [Suppl B]:131?134","journal-title":"J Antimicrob Chemother"},{"key":"CR14","first-page":"296","volume":"14","author":"R Norrby","year":"1978","unstructured":"Norrby R (1978) A review of the penetration of antibiotics into CSF and its clinical significance. Scand J Infect Dis [Suppl] 14: 296?309","journal-title":"Scand J Infect Dis [Suppl]"},{"issue":"Suppl B","key":"CR15","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1093\/jac\/8.suppl_B.23","volume":"8","author":"I Phillips","year":"1981","unstructured":"Phillips I, Warren C, Shannon K, King A, Hanslo D (1981) Ceftazidime: in vitro antibacterial activity and susceptibility to beta-lactamases compared with that of cefotaxime, moxalactam and other beta-lactam antibiotics. J Antimicrob Chemother 8 [Suppl B]:25?31","journal-title":"J Antimicrob Chemother"},{"key":"CR16","doi-asserted-by":"crossref","first-page":"408","DOI":"10.1097\/00006454-198607000-00006","volume":"5","author":"WJ Rodriguez","year":"1986","unstructured":"Rodriguez WJ, Puig JR, Khan WH, Feris J, Gold BG, Sturla C (1986) Ceftazidime vs standard therapy for pediatric meningitis: therapeutic, pharmacologic and epidemiologic observations. Pediatr Infect Dis 5:408?415","journal-title":"Pediatr Infect Dis"},{"key":"CR17","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1111\/j.1469-8749.1983.tb13738.x","volume":"25","author":"A Statz","year":"1983","unstructured":"Statz A, Feigenhauer K (1983) Development of the blood-CSF barrier. Develop Med Child Neurol 25:152?161","journal-title":"Develop Med Child Neurol"},{"key":"CR18","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1111\/j.1749-6632.1967.tb50247.x","volume":"145","author":"LH Taber","year":"1967","unstructured":"Taber LH, Yow MD, Nieberg FG (1967) The penetration of broad spectrum antibiotics into the cerebrospinal fluid. Ann NY Acad Sci 145:473?481","journal-title":"Ann NY Acad Sci"},{"key":"CR19","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1007\/BF00496420","volume":"147","author":"I Tessin","year":"1988","unstructured":"Tessin I, Thiringer K, Trollfors B, Brorson J-E (1988) Comparison of serum concentrations of ceftazidime and tobramycin in newborn infants. Eur J Pediatr 147:405?407","journal-title":"Eur J Pediatr"},{"key":"CR20","unstructured":"Thrupp Ld, Leedom JM, Ivler D, Wehrle PF, Portnoy B, Matthies AW (1966) Ampicillin levels in cerebrospinal fluid during treatment of bacterial meningitis. Antimicrob Agents Chemother, pp 206?213"},{"key":"CR21","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1128\/AAC.21.3.525","volume":"21","author":"CU Tuazon","year":"1982","unstructured":"Tuazon CU, Shamsuddin D, Miller A (1982) Antibiotic susceptibility and synergy of clinical isolates of Listeria monocytogenes. Antimicrob Agents Chemother 21:525?527","journal-title":"Antimicrob Agents Chemother"},{"issue":"Suppl B","key":"CR22","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1093\/jac\/8.suppl_B.53","volume":"8","author":"ID Wilkinson","year":"1981","unstructured":"Wilkinson ID, Gentry LO (1981) In vitro comparison of ceftazidime and nine other antimicrobial agents against hospital strains of Gram-negative bacteria. J Antimicrob Chemother 8 [Suppl B]: 53?56","journal-title":"J Antimicrob Chemother"}],"container-title":["European Journal of Pediatrics"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF00441533.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/BF00441533\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF00441533","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,4,4]],"date-time":"2019-04-04T00:38:08Z","timestamp":1554338288000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/BF00441533"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1989,6]]},"references-count":22,"journal-issue":{"issue":"7","published-print":{"date-parts":[[1989,6]]}},"alternative-id":["BF00441533"],"URL":"https:\/\/doi.org\/10.1007\/bf00441533","relation":{},"ISSN":["0340-6199","1432-1076"],"issn-type":[{"value":"0340-6199","type":"print"},{"value":"1432-1076","type":"electronic"}],"subject":[],"published":{"date-parts":[[1989,6]]}}}