{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,27]],"date-time":"2026-05-27T19:52:58Z","timestamp":1779911578365,"version":"3.53.1"},"reference-count":15,"publisher":"Springer Science and Business Media LLC","issue":"S1","license":[{"start":{"date-parts":[[1989,1,1]],"date-time":"1989-01-01T00:00:00Z","timestamp":599616000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Psychopharmacology"],"published-print":{"date-parts":[[1989]]},"DOI":"10.1007\/bf00442567","type":"journal-article","created":{"date-parts":[[2004,11,12]],"date-time":"2004-11-12T04:46:26Z","timestamp":1100234786000},"page":"S84-S86","source":"Crossref","is-referenced-by-count":37,"title":["A retrospective study on the long-term efficacy of clozapine in 96 schizophrenic and schizoaffective patients during a 13-year period"],"prefix":"10.1007","volume":"99","author":[{"given":"Leif H.","family":"Lindstr\ufffdm","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"CR1","doi-asserted-by":"crossref","first-page":"346","DOI":"10.1111\/j.2042-7158.1973.tb10025.x","volume":"25","author":"NE Anden","year":"1973","unstructured":"Anden NE, Stock G (1973) Effect of clozapine on the turnover of dopamine in the corpus striatum and in the limbic system. J Pharm Pharmacol 25:346?348","journal-title":"J Pharm Pharmacol"},{"key":"CR2","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1007\/BF00606410","volume":"11","author":"B Anderman","year":"1977","unstructured":"Anderman B, Griffith RW (1977) Clozapine-induced agranulocytosis: a situation report up to August 1976. Eur J Clin Pharmacol 11:199?201","journal-title":"Eur J Clin Pharmacol"},{"key":"CR3","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1055\/s-0028-1094312","volume":"4","author":"J Angst","year":"1971","unstructured":"Angst J (1971) Ergebnisse eines Doppelblindversuches von HF 1854 (8-chlor-1-(4-methyl-1-piperazinyl)-5H-dibenzo(b,e) 1,4)diazepin im Vergleich zu Levomepromazine. Pharmacopsychiatry 4:192?200","journal-title":"Pharmacopsychiatry"},{"key":"CR4","doi-asserted-by":"crossref","first-page":"736","DOI":"10.1111\/j.1476-5381.1972.tb06898.x","volume":"46","author":"G Bartholini","year":"1972","unstructured":"Bartholini G, Haefely W, Jalfre M, Keller HH, Pletcher A (1972) Effects of clozapine on cerebral catecholaminergic neuron systems. Br J Pharmacol 46:736?740","journal-title":"Br J Pharmacol"},{"key":"CR5","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1093\/schbul\/6.1.70","volume":"6","author":"JM Davis","year":"1980","unstructured":"Davis JM, Schaffer CB, Killian GA, Kinard C, Chan C (1980) Important issues in the drug treatment of schizophrenia. Schizophren Bull 6:70?87","journal-title":"Schizophren Bull"},{"key":"CR6","first-page":"945","volume":"16","author":"B Ekblom","year":"1974","unstructured":"Ekblom B, H\u00e4ggstr\u00f6m JE (1974) Clozapine (Leponex) compared with chlorpromazine: a double-blind evaluation of pharmacological and clinical properties. Curr Ther Res 16:945?957","journal-title":"Curr Ther Res"},{"key":"CR7","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1159\/000468175","volume":"10","author":"R Fog","year":"1975","unstructured":"Fog R (1975) Neuroleptic action of clozapine injected into various brain areas in rats. Int Pharmacopsychiatry 10:89?93","journal-title":"Int Pharmacopsychiatry"},{"key":"CR8","doi-asserted-by":"crossref","first-page":"410","DOI":"10.1111\/j.1600-0447.1974.tb09706.x","volume":"50","author":"J Gerlach","year":"1974","unstructured":"Gerlach J, Koppelhus P, Helweg E, Monrad A (1974) Clozapine and haloperidol in a single-blind cross-over trial: therapeutic and biochemical aspects in the treatment of schizophrenia. Acta Psychiatr Scand 50:410?424","journal-title":"Acta Psychiatr Scand"},{"key":"CR9","first-page":"1103","volume-title":"Psychopharmacology, the third generation of progress: the emergence of molecular biology and biological psychiatry","author":"JM Kane","year":"1987","unstructured":"Kane JM, Lieberman J (1987) Maintenance pharmacotherapy in schizophrenia. In: Meltzer HY (ed) Psychopharmacology, the third generation of progress: the emergence of molecular biology and biological psychiatry. Raven Press, New York, pp 1103?1109"},{"key":"CR10","doi-asserted-by":"crossref","first-page":"789","DOI":"10.1001\/archpsyc.1988.01800330013001","volume":"45","author":"JM Kane","year":"1988","unstructured":"Kane JM, Honigfeld G, Singer J, Meltzer H (1988) Clozapine for the treatment-resistant schizophrenic; a double-blind comparison with chlorpromazine. Arch Gen Psychiatry 45:789?796","journal-title":"Arch Gen Psychiatry"},{"key":"CR11","first-page":"225","volume":"40","author":"S Kuha","year":"1986","unstructured":"Kuha S, Miettinen E (1986) Long-term effect of clozapine in schizophrenia: a retrospective study of 108 chronic schizophrenics treated with clozapine for up to 12 years. Nord Psychiatr Tidskr 40:225?230","journal-title":"Nord Psychiatr Tidskr"},{"key":"CR12","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1111\/j.1600-0447.1979.tb00246.x","volume":"59","author":"CA Leon","year":"1979","unstructured":"Leon CA (1979) Therapeutic effect of clozapine. A 4-year follow-up of a controlled clinical trial. Acta Psychiatr Scand 59:471?480","journal-title":"Acta Psychiatr Scand"},{"key":"CR13","first-page":"49","volume":"2","author":"H Nyb\u00e4ck","year":"1976","unstructured":"Nyb\u00e4ck H, Sedvall G (1976) Effects of neuroleptics on striatal dopamine synthesized from 14C-tyrosine. Pharmacol Ther 2:49?63","journal-title":"Pharmacol Ther"},{"key":"CR14","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1111\/j.1600-0447.1985.tb01268.x","volume":"71","author":"UJ Povlsen","year":"1985","unstructured":"Povlsen UJ, Noring U, Fog R, Gerlach J (1985) Tolerability and therapeutic effect of clozapine; a retrospective investigation of 216 patients treated with clozapine for up to 12 years. Acta Psychiatr Scand 71:176?185","journal-title":"Acta Psychiatr Scand"},{"key":"CR15","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1007\/BF00421063","volume":"41","author":"AC Sayers","year":"1975","unstructured":"Sayers AC, Burki HR, Ruch W, Aspen A (1975) Neuroleptic-induced hypersensitivity of striatal dopamine receptors in the rat as a model of tardiv dyskinesias. Effects of clozapine, haloperidol, loxapine and chlorpromazine. Psychopharmacologia 41:97?104","journal-title":"Psychopharmacologia"}],"container-title":["Psychopharmacology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF00442567.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/BF00442567\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF00442567","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,4,4]],"date-time":"2019-04-04T00:38:35Z","timestamp":1554338315000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/BF00442567"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1989]]},"references-count":15,"journal-issue":{"issue":"S1","published-print":{"date-parts":[[1989]]}},"alternative-id":["BF00442567"],"URL":"https:\/\/doi.org\/10.1007\/bf00442567","relation":{},"ISSN":["0033-3158","1432-2072"],"issn-type":[{"value":"0033-3158","type":"print"},{"value":"1432-2072","type":"electronic"}],"subject":[],"published":{"date-parts":[[1989]]}}}