{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,3]],"date-time":"2025-11-03T08:57:58Z","timestamp":1762160278944},"reference-count":32,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[1986,8,1]],"date-time":"1986-08-01T00:00:00Z","timestamp":523238400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Eur J Pediatr"],"published-print":{"date-parts":[[1986,8]]},"DOI":"10.1007\/bf00446060","type":"journal-article","created":{"date-parts":[[2004,11,12]],"date-time":"2004-11-12T08:51:31Z","timestamp":1100249491000},"page":"182-184","source":"Crossref","is-referenced-by-count":25,"title":["Auto-immunity in children with diabetes mellitus and in their relatives"],"prefix":"10.1007","volume":"145","author":[{"given":"R.","family":"Lorini","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.","family":"Larizza","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Livieri","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"V.","family":"Cammareri","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Martini","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Plebani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.","family":"Zanaboni","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F.","family":"Severi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"CR1","doi-asserted-by":"crossref","first-page":"585","DOI":"10.2337\/diab.31.7.585","volume":"31","author":"J Barbosa","year":"1982","unstructured":"Barbosa J, Chavers B, Dunsworth T, Michael A (1982) Islet cell antibodies and histocompatibility antigens (HLA) in insulin-dependent diabetics and their first-degree relatives. Diabetes 31:585?588","journal-title":"Diabetes"},{"key":"CR2","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1007\/BF00262215","volume":"26","author":"C Betterle","year":"1984","unstructured":"Betterle C, Zanette F, Pedini B, Presotto F, Rapp LB, Monciotti CM, Rigon F (1984) Clinical and subclinical organ-specific autoimmune manifestations in Type 1 (insulin-dependent) diabetic patients and their first-degree relatives. Diabetologia 26:431?436","journal-title":"Diabetologia"},{"key":"CR3","doi-asserted-by":"crossref","first-page":"1279","DOI":"10.1016\/S0140-6736(74)90140-8","volume":"2","author":"GF Bottazzo","year":"1974","unstructured":"Bottazzo GF, Florin-Christensen A, Doniach D (1974) Islet-cell antibodies in diabetes mellitus with autoimmune polyendocrine deficiencies. Lancet 2:1279?1283","journal-title":"Lancet"},{"key":"CR4","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1136\/bmj.2.6131.165","volume":"2","author":"GF Bottazzo","year":"1978","unstructured":"Bottazzo GF, Mann JI, Thorogood M, Baum JD, Doniach D (1978) Autoimmunity in juvenile diabetics and their families. Br Med J 2:165?168","journal-title":"Br Med J"},{"key":"CR5","doi-asserted-by":"crossref","first-page":"668","DOI":"10.1016\/S0140-6736(80)92825-1","volume":"1","author":"GF Bottazzo","year":"1980","unstructured":"Bottazzo GF, Dean BM, Gorsuch AN, Cudworth AG, Doniach D (1980) Complement-fixing islet-cell antibodies in type-I diabetes: possible monitors of active beta-cell damage. Lancet 1: 668?672","journal-title":"Lancet"},{"key":"CR6","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/S0260-4639(22)00014-7","volume":"1","author":"GF Bottazzo","year":"1981","unstructured":"Bottazzo GF, Pujol-Borrell R, Doniach D (1981) Humoral and cellular immunity in diabetes mellitus. Clin Immunol Allergy 1:63?80","journal-title":"Clin Immunol Allergy"},{"key":"CR7","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1007\/BF00283644","volume":"26","author":"GF Bottazzo","year":"1984","unstructured":"Bottazzo GF (1984) Beta-cell damage in diabetic insulitis: are we approaching a solution? Diabetologia 26:241?249","journal-title":"Diabetologia"},{"key":"CR8","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1016\/S0022-3476(82)80227-8","volume":"100","author":"GM Bright","year":"1982","unstructured":"Bright GM, Blizzard RM, Kaiser DL, Clarke WL (1982) Organ-specific autoantibodies in children with common endocrine diseases. J Pediatr 100:8?14","journal-title":"J Pediatr"},{"key":"CR9","doi-asserted-by":"crossref","first-page":"1454","DOI":"10.1056\/NEJM198106113042403","volume":"304","author":"GF Cahill","year":"1981","unstructured":"Cahill GF, McDevitt HO (1981) Insulin-dependent diabetes mellitus: the initial lesion. N Engl J Med 304:1454?1465","journal-title":"N Engl J Med"},{"key":"CR10","first-page":"2795","volume":"10","author":"H Dorchy","year":"1981","unstructured":"Dorchy H, Lemiere B, Toussaint D, Gausset Ph (1981) Anticorps anti-cellules des ilots de Langerhans et sp\ufffdcifiques d'organes chez les jeunes diabetiques. Relation avec l'age, le d\ufffdbut et la dur\ufffde du diab\ufffdte, la s\ufffdcr\ufffdtion r\ufffdsiduelle d'insuline et la r\ufffdtinopathie. Nouv Presse M\ufffdd 10:2795?2798","journal-title":"Nouv Presse M\ufffdd"},{"key":"CR11","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1111\/j.1651-2227.1983.tb09677.x","volume":"72","author":"H Dorchy","year":"1983","unstructured":"Dorchy H (1983) Organ-specific antibodies in young diabetics. Acta Paediatr Scand 72:131?132","journal-title":"Acta Paediatr Scand"},{"key":"CR12","doi-asserted-by":"crossref","first-page":"386","DOI":"10.1111\/j.1651-2227.1985.tb10989.x","volume":"74","author":"H Dorchy","year":"1985","unstructured":"Dorchy H, Bourdoux P, Lemiere B (1985) Subclinical thyroid hormone abnormalities in type I diabetic children and adolescents. Relationship to metabolic control. Acta Paediatr Scand 74:386?389","journal-title":"Acta Paediatr Scand"},{"key":"CR13","unstructured":"Editorial (1982) Thyroid disease in young diabetics. Lancet I:1285?1286"},{"key":"CR14","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1016\/S0022-3476(70)80342-0","volume":"77","author":"DE Goldstein","year":"1970","unstructured":"Goldstein DE, Drash A, Gibbs J, Blizzard RM (1970) Diabetes mellitus: the incidence of circulating antibodies against thyroid, gastric, and adrenal tissue. J Pediatr 77:304?306","journal-title":"J Pediatr"},{"key":"CR15","doi-asserted-by":"crossref","first-page":"1363","DOI":"10.1016\/S0140-6736(81)92795-1","volume":"II","author":"AN Gorsuch","year":"1981","unstructured":"Gorsuch AN, Spencer KM, Lister J, McNally JM, Dean BM, Bottazzo GF, Cudworth AG (1981) Evidence for a long prediabetic period in type I (insulin-dependent) diabetes mellitus. Lancet II:1363?1365","journal-title":"Lancet"},{"key":"CR16","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1111\/j.1651-2227.1980.tb07119.x","volume":"69","author":"J Kokkonen","year":"1980","unstructured":"Kokkonen J (1980) Parietal cell antibodies and gastric secretion in children with diabetes mellitus. Acta Paediatr Scand 69:485?489","journal-title":"Acta Paediatr Scand"},{"key":"CR17","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1111\/j.1651-2227.1982.tb09403.x","volume":"71","author":"J Kokkonen","year":"1982","unstructured":"Kokkonen J, Kiuttu J, Mustonen A, Rasanen O (1982) Organ-specific antibodies in healthy and diabetic children and young adults. Acta Paediatr Scand 71:223?226","journal-title":"Acta Paediatr Scand"},{"key":"CR18","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1136\/bmj.1.6009.553","volume":"I","author":"R Lendrum","year":"1976","unstructured":"Lendrum R, Nelson PG, Pyke DA, Walker G, Gamble DR (1976) Islet-cell, thyroid, and gastric autoantibodies in diabetic identical twins. Br Med J I:553?555","journal-title":"Br Med J"},{"key":"CR19","doi-asserted-by":"crossref","first-page":"755","DOI":"10.1016\/S0140-6736(82)91809-8","volume":"I","author":"R Mirakian","year":"1982","unstructured":"Mirakian R, Cudworth AG, Bottazzo GF, Richardson CA, Doniach D (1982) Autoimmunity to anterior pituitary cells and the pathogenesis of insulin-dependent diabetes mellitus. Lancet I:755?759","journal-title":"Lancet"},{"key":"CR20","doi-asserted-by":"crossref","first-page":"589","DOI":"10.2337\/diab.29.8.589","volume":"29","author":"M Neufeld","year":"1980","unstructured":"Neufeld M, MacLaren NK, Riley WJ, Lezotte D, McLaughlin JV, Silverstein J, Rosenbloom AL (1980) Islet cell and other organ-specific antibodies in U.S. caucasians and blacks with insulin-dependent diabetes mellitus. Diabetes 29:589?592","journal-title":"Diabetes"},{"key":"CR21","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1016\/S0022-3476(80)80472-0","volume":"97","author":"WJ Riley","year":"1980","unstructured":"Riley WJ, MacLaren NK, Neufeld M (1980) Adrenal autoantibodies and Addison disease in insulin-dependent diabetes mellitus. J Pediatr 97:191?195","journal-title":"J Pediatr"},{"key":"CR22","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1016\/S0022-3476(81)80316-2","volume":"99","author":"WJ Riley","year":"1981","unstructured":"Riley WJ, MacLaren NK, Lezotte DC, Spillar RP, Rosenbloom AL (1981) Thyroid autoimmunity in insulin dependent diabetes mellitus: the case for routine screening. J Pediatr 99:350?354","journal-title":"J Pediatr"},{"key":"CR23","doi-asserted-by":"crossref","first-page":"1051","DOI":"10.2337\/diacare.31.12.1051","volume":"31","author":"WJ Riley","year":"1982","unstructured":"Riley WJ, Toskes PP, MacLaren NK, Silverstein JH (1982) Predictive value for gastric parietal cell autoantibodies as a marker for gastric and hematologic abnormalities associated with insulin-dependent diabetes. Diabetes 31:1051?1055","journal-title":"Diabetes"},{"key":"CR24","doi-asserted-by":"crossref","first-page":"418","DOI":"10.1007\/BF00257339","volume":"24","author":"WJ Riley","year":"1983","unstructured":"Riley WJ, Winer A, Goldstein D (1983) Coincident presence of thyro-gastric autoimmunity at onset of type 1 (insulin-dependent) diabetes. Diabetologia 24:418?421","journal-title":"Diabetologia"},{"key":"CR25","doi-asserted-by":"crossref","first-page":"317","DOI":"10.2337\/diab.29.4.317","volume":"29","author":"HG Rittenhouse","year":"1980","unstructured":"Rittenhouse HG, Oxender DL, Pek S, Ar D (1980) Complement mediated cytotoxic effects on pancreatic islets, with sera from diabetic patients. Diabetes 29:317?322","journal-title":"Diabetes"},{"key":"CR26","doi-asserted-by":"crossref","first-page":"841","DOI":"10.1136\/jcp.26.11.841","volume":"26","author":"M Rizzetto","year":"1973","unstructured":"Rizzetto M, Doniach D (1973) Types of ?reticulin? antibodies detected in human sera by immunofluorescence. J Clin Pathol 26:841?851","journal-title":"J Clin Pathol"},{"key":"CR27","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1007\/BF00262010","volume":"20","author":"M Sensi","year":"1981","unstructured":"Sensi M, Pozzilli P, Gorsuch AN, Bottazzo GF, Cudworth AG (1981) Increased killer cell activity in insulin dependent (type I) diabetes mellitus. Diabetologia 20:106?109","journal-title":"Diabetologia"},{"key":"CR28","doi-asserted-by":"crossref","first-page":"764","DOI":"10.1016\/S0140-6736(84)91278-9","volume":"I","author":"KM Spencer","year":"1984","unstructured":"Spencer KM, Tarn A, Dean BM, Lister J, Bottazzo GF (1984) Fluctuating islet-cell autoimmunity in unaffected relatives of patients with insulin-dependent diabetes. Lancet I:764?766","journal-title":"Lancet"},{"key":"CR29","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1056\/NEJM198508223130801","volume":"313","author":"S Srikanta","year":"1985","unstructured":"Srikanta S, Ganda OP, Rabizadeh A, Stuart Soeldner J, Eisenbarth GS (1985) First-degree relatives of patients with type I diabetes mellitus. N Engl J Med 313:461?464","journal-title":"N Engl J Med"},{"key":"CR30","doi-asserted-by":"crossref","first-page":"855","DOI":"10.2337\/diab.34.9.855","volume":"34","author":"Y Toguchi","year":"1985","unstructured":"Toguchi Y, Ginsberg-Fellner F, Rubinstein P (1985) Cytotoxic islet cell surface antibodies (ICSA) in patients with type I diabetes and their first-degree relatives. Diabetes 34:855?860","journal-title":"Diabetes"},{"key":"CR31","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1007\/BF00540246","volume":"142","author":"F Trimarchi","year":"1984","unstructured":"Trimarchi F, De Luca F, Vanelli M, Benvenga S, Siracusano MF, Volta C, Bernasconi S (1984) Circulating thyroid antibodies and thyroid function studies in children and adolescents with insulin-dependent diabetes mellitus. Eur J Pediatr 142:253?256","journal-title":"Eur J Pediatr"},{"key":"CR32","doi-asserted-by":"crossref","first-page":"1173","DOI":"10.1056\/NEJM197905243002102","volume":"300","author":"Jw Yoon","year":"1979","unstructured":"Yoon Jw, Austin M, Onodera T, Notkins AL (1979) Virus-induced diabetes mellitus. Isolation of a virus from the pancreas of a child with diabetic ketoacidosis. N Engl J Med 300:1173?1179","journal-title":"N Engl J Med"}],"container-title":["European Journal of Pediatrics"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF00446060.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/BF00446060\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF00446060","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,30]],"date-time":"2023-04-30T05:18:28Z","timestamp":1682831908000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/BF00446060"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1986,8]]},"references-count":32,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1986,8]]}},"alternative-id":["BF00446060"],"URL":"https:\/\/doi.org\/10.1007\/bf00446060","relation":{},"ISSN":["0340-6199","1432-1076"],"issn-type":[{"value":"0340-6199","type":"print"},{"value":"1432-1076","type":"electronic"}],"subject":[],"published":{"date-parts":[[1986,8]]}}}