{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T05:46:01Z","timestamp":1761630361819},"reference-count":33,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[1990,6,1]],"date-time":"1990-06-01T00:00:00Z","timestamp":644198400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Theor Med Bioeth"],"published-print":{"date-parts":[[1990,6]]},"DOI":"10.1007\/bf00489452","type":"journal-article","created":{"date-parts":[[2004,11,16]],"date-time":"2004-11-16T07:40:19Z","timestamp":1100590819000},"page":"87-94","source":"Crossref","is-referenced-by-count":42,"title":["The ethical assessment of innovative therapies: Liver transplantation using living donors"],"prefix":"10.1007","volume":"11","author":[{"given":"Peter A.","family":"Singer","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mark","family":"Siegler","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John D.","family":"Lantos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jean C.","family":"Emond","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter F.","family":"Whitington","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. Richard","family":"Thistlethwaite","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christoph E.","family":"Broelsch","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"CR1","doi-asserted-by":"crossref","first-page":"614","DOI":"10.1002\/hep.1840020516","volume":"2","author":"TE Starzl","year":"1982","unstructured":"Starzl TE, Iwatsuki S, VanThiel D, et al. Evolution of liver transplantation. Hepatology 1982;2:614?36.","journal-title":"Hepatology"},{"key":"CR2","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1097\/00007890-198803000-00003","volume":"45","author":"CE Broelsch","year":"1988","unstructured":"Broelsch CE, Emond JC, Thistlethwaite JR, Rouch DA, Whitington PF, Lictor JL: Liver transplantation with reduced-sized donor organs. Transplantation 1988;45:519?24.","journal-title":"Transplantation"},{"key":"CR3","doi-asserted-by":"crossref","first-page":"867","DOI":"10.1002\/hep.1840100520","volume":"10","author":"JC Emond","year":"1989","unstructured":"Emond JC, Whitington PF, Thistlethwaite JR, Alonso EA, Broelsch CE. Reduced-size orthotopic liver transplantation: use in the management of children with chronic liver disease. Hepatology 1989;10:867?72.","journal-title":"Hepatology"},{"key":"CR4","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1016\/S0022-3476(87)80105-1","volume":"111","author":"JJ Malatack","year":"1987","unstructured":"Malatack JJ, Schaid DJ, Urbach AH, et al. Choosing a pediatric recipient for orthotopic liver transplantation. J Pediatr 1987;111:479?89.","journal-title":"J Pediatr"},{"key":"CR5","doi-asserted-by":"crossref","first-page":"484","DOI":"10.1002\/hep.1840070312","volume":"7","author":"RR Peleman","year":"1987","unstructured":"Peleman RR, Gavaler JS, VanThiel DH, et al. Orthotopic liver transplantation for acute and subacute hepatic failure in adults. Hepatology 1987;7:484?9.","journal-title":"Hepatology"},{"key":"CR6","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1001\/archpedi.1985.02140060063030","volume":"139","author":"JD Lloyd-Still","year":"1985","unstructured":"Lloyd-Still JD. Mortality from liver disease in children: implications for hepatic transplantation. Am J Dis Child 1985;139:381?4.","journal-title":"Am J Dis Child"},{"issue":"4","key":"CR7","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1377\/hlthaff.7.5.65","volume":"7","author":"KS Andersen","year":"1988","unstructured":"Andersen KS, Fox DM. The impact of routine inquiry laws on organ donation. Health Aff 1988;7(4):65?78.","journal-title":"Health Aff"},{"key":"CR8","doi-asserted-by":"crossref","first-page":"410","DOI":"10.1097\/00000658-198810000-00003","volume":"208","author":"CE Broelsch","year":"1988","unstructured":"Broelsch CE, Edmond JC, Thistlethwaite JR, et al. LIver transplantation, including the concept of reduced-size liver transplants in children. Ann Surg 1988;208:410?20.","journal-title":"Ann Surg"},{"key":"CR9","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1203\/00006450-198901000-00023","volume":"25","author":"EM Alonso","year":"1989","unstructured":"Alonso EM, Whitington PF, Broelsch CE, Emond JC, Thistlethwaite JR. ?Split-liver? orthotopic liver transplantation. Pediatr Res 1989;25:107.","journal-title":"Pediatr Res"},{"key":"CR10","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1016\/S0140-6736(89)92101-6","volume":"2","author":"S Raia","year":"1989","unstructured":"Raia S, Nery JR, Mies S. Liver transplantation from live donors. [Letter]. Lancet 1989;2:497.","journal-title":"Lancet"},{"key":"CR11","doi-asserted-by":"crossref","first-page":"376","DOI":"10.1016\/0002-9610(66)90206-6","volume":"112","author":"WV McDermott","year":"1966","unstructured":"McDermott WV, Ottinger W. Elective hepatic resection. Am J Surg 1966;112:376?81.","journal-title":"Am J Surg"},{"key":"CR12","first-page":"209","volume":"150","author":"TE Starzl","year":"1980","unstructured":"Starzl TE, Weil R, Putnam CW. Right trisegmentectomy for hepatic neoplasms. Surg Gynecol Obstet 1980;150:209?13.","journal-title":"Surg Gynecol Obstet"},{"key":"CR13","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1016\/S0039-6109(16)42342-X","volume":"61","author":"M Adson","year":"1981","unstructured":"Adson M. Diagnosis and surgical treatment of primary and secondary solid hepatic tumors in the adult. Surg Clin North Am 1981;61:181?92.","journal-title":"Surg Clin North Am"},{"key":"CR14","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1097\/00000658-198303000-00001","volume":"197","author":"S Iwatsuki","year":"1983","unstructured":"Iwatsuki S, Shaw BW, Starzl TE. Experience with 150 liver resections. Ann Surg 1983;197:247?53.","journal-title":"Ann Surg"},{"key":"CR15","first-page":"342","volume":"109","author":"H Bismuth","year":"1983","unstructured":"Bismuth H, Houssin D, Mitchel F. Le risque operatoire des hepatectomies: experience sur 154 hepatectomies: a propos de la communication de M.D. Rohner sur les hepatectomies, seance de 3 fevrier 1982. Chirurgie 1983;109:342?8.","journal-title":"Chirurgie"},{"key":"CR16","first-page":"483","volume-title":"Aspekte der Klinischen Onkologie","author":"CE Broelsch","year":"1984","unstructured":"Broelsch CE, Neuhaus P, Ringe B, Long W, Pichlmayr R. Hepatic resection in primary and secondary liver tumors. In: Axel-Girigi H, ed. Aspekte der Klinischen Onkologie. Stuttgart: Gustav Fischer Verlag 1984:483."},{"key":"CR17","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1097\/00000658-198507000-00006","volume":"202","author":"T Nagao","year":"1985","unstructured":"Nagao T, Inoue S, Mizuta T, Saito H, Kawano N, Morioka Y. One hundred hepatic resections: indications and operative results. Ann Surg 1985;202:42?9.","journal-title":"Ann Surg"},{"key":"CR18","first-page":"291","volume-title":"Surgery Annual, Vol 20","author":"H Bismuth","year":"1988","unstructured":"Bismuth H, Castaing D, Garden OJ. Segmental surgery of the liver. In: Nyhus L, ed. Surgery Annual, Vol 20. Norwalk: Appleton & Lange 1988:291?310."},{"key":"CR19","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1016\/0002-9610(69)90288-8","volume":"117","author":"HH Stone","year":"1969","unstructured":"Stone HH, Long WD, Smith RB, Haynes CD. Physiologic considerations in major hepatic resections. Am J Surg 1969;117:78?84.","journal-title":"Am J Surg"},{"key":"CR20","first-page":"367","volume":"95","author":"H Bismuth","year":"1984","unstructured":"Bismuth H, Houssin D. Reducted-size orthotopic liver graft in hepatic transplantation in children. Surgery 1984;95:367?71.","journal-title":"Surgery"},{"key":"CR21","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1093\/jmp\/4.1.32","volume":"4","author":"ED Pellegrino","year":"1979","unstructured":"Pellegrino ED. Toward a reconstruction of medical morality: the primacy of the act of profession and the fact of illness. J Med Philos 1979;4:32?56.","journal-title":"J Med Philos"},{"key":"CR22","first-page":"21","volume-title":"Medical Innovation and Bad Outcomes: Legal, Social and Ethical Responses","author":"S Toulmin","year":"1987","unstructured":"Toulmin S. Technological progress and social policy: the broader significance of medical mishaps. In: Siegler M, Toulmin S, Zimring FE, Schaffner KF, eds. Medical Innovation and Bad Outcomes: Legal, Social and Ethical Responses. Ann Arbor, MI: Health Administration Press, 1987:21?34."},{"key":"CR23","first-page":"5","volume":"28","author":"CW Lillehei","year":"1982","unstructured":"Lillehei CW. A personalized history of extracorporeal circulation. Transactions ? American Society for Artificial Internal Organs 1982;28:5?19.","journal-title":"Transactions ? American Society for Artificial Internal Organs"},{"key":"CR24","doi-asserted-by":"crossref","first-page":"324","DOI":"10.1046\/j.1537-2995.1986.26486262738.x","volume":"26","author":"NC Briggs","year":"1986","unstructured":"Briggs NC, Piliavin JA, Lorentzen D, Becker GA. On willingness to be a bone marrow donor. Transfusion 1986;26:324?30.","journal-title":"Transfusion"},{"key":"CR25","first-page":"1","volume":"5","author":"A Spital","year":"1988","unstructured":"Spital A. Living kidney donation: when is it justified? American Kidney Fund Nephrology Letter 1988;5:1?15.","journal-title":"American Kidney Fund Nephrology Letter"},{"key":"CR26","first-page":"16","volume":"5","author":"PA Singer","year":"1988","unstructured":"Singer PA, Siegler M. Whose kidney is it anyway? Ethical considerations in living kidney donation. American Kidney Fund Nephrology Letter 1988;5:16?20.","journal-title":"American Kidney Fund Nephrology Letter"},{"issue":"Suppl","key":"CR27","doi-asserted-by":"crossref","first-page":"101","DOI":"10.2337\/diab.38.1.S101","volume":"38","author":"DM Kendall","year":"1989","unstructured":"Kendall DM, Sutherland DE, Goetz FC, Najarian JS. Metabolic effect of hemipancreatectomy in donors. Preoperative prediction of postoperative oral glucose tolerance. Diabetes 1989;38(Suppl):101?3.","journal-title":"Diabetes"},{"key":"CR28","doi-asserted-by":"crossref","first-page":"620","DOI":"10.1056\/NEJM198908313210919","volume":"321","author":"PA Singer","year":"1989","unstructured":"Singer PA, Siegler M, Whitington PF, et al. Ethics of liver transplantation with living donors, N Engl J Med 1989;321:620?2.","journal-title":"N Engl J Med"},{"key":"CR29","series-title":"DHEW publication no OS-78-0013","volume-title":"The Belmont Report: Ethical Principles and Guidelines for the Protection of Human Subjects of Research","author":"The National Commission for the Protection of Human Subjects of Biomedical and Behavioral Research","year":"1978","unstructured":"The National Commission for the Protection of Human Subjects of Biomedical and Behavioral Research. The Belmont Report: Ethical Principles and Guidelines for the Protection of Human Subjects of Research. Washington, DC: US Government Printing Office, 1978. (DHEW publication no OS-78-0013)."},{"key":"CR30","volume-title":"Ethics and Regulation of Clinical Research","author":"RJ Levine","year":"1986","unstructured":"Levine RJ. Ethics and Regulation of Clinical Research. 2nd ed. Baltimore: Urban & Schwarzenberg, 1986.","edition":"2nd ed."},{"key":"CR31","first-page":"546","volume":"36","author":"SE Lind","year":"1988","unstructured":"Lind SE. Innovative medical therapies: between research and practice. Clin Res 1988;36:546?51.","journal-title":"Clin Res"},{"key":"CR32","first-page":"539","volume":"36","author":"PA Singer","year":"1988","unstructured":"Singer PA, Lantos JD, Whitington PF, Broelsch CE, Siegler M. Equipoise and the ethics of segmental liver transplantation. Clin Res 1988;36:539?45.","journal-title":"Clin Res"},{"key":"CR33","unstructured":"Boodman SG. New era in transplants. Washington Post 1989 Dec 19 (Health Sec):10?2."}],"container-title":["Theoretical Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF00489452.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/BF00489452\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF00489452","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,4,4]],"date-time":"2019-04-04T16:18:46Z","timestamp":1554394726000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/BF00489452"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1990,6]]},"references-count":33,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1990,6]]}},"alternative-id":["BF00489452"],"URL":"https:\/\/doi.org\/10.1007\/bf00489452","relation":{},"ISSN":["0167-9902","1573-1200"],"issn-type":[{"value":"0167-9902","type":"print"},{"value":"1573-1200","type":"electronic"}],"subject":[],"published":{"date-parts":[[1990,6]]}}}