{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,21]],"date-time":"2026-02-21T03:41:51Z","timestamp":1771645311465,"version":"3.50.1"},"reference-count":19,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[1982,1,1]],"date-time":"1982-01-01T00:00:00Z","timestamp":378691200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Naunyn-Schmiedeberg's Arch. Pharmacol."],"published-print":{"date-parts":[[1982]]},"DOI":"10.1007\/bf00495863","type":"journal-article","created":{"date-parts":[[2004,11,16]],"date-time":"2004-11-16T14:27:58Z","timestamp":1100615278000},"page":"185-188","source":"Crossref","is-referenced-by-count":8,"title":["Transport of organic ions through lipid bilayers"],"prefix":"10.1007","volume":"319","author":[{"given":"Peter G.","family":"Ruifrok","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"CR1","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1042\/bj0760047","volume":"76","author":"WN Aldridge","year":"1960","unstructured":"Aldridge WN, Parker VH (1960) Barbiturates and oxidative phosphorylation. Biochem J 76:47?56","journal-title":"Biochem J"},{"key":"CR2","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1111\/j.1432-1033.1979.tb04253.x","volume":"102","author":"J Boonstra","year":"1979","unstructured":"Boonstra J, Ottema S, Sips HJ, Konings WN (1979) Uncoupling action of amytal in membrane vesciles from E. coli. Eur J Biochem 102:383?388","journal-title":"Eur J Biochem"},{"key":"CR3","first-page":"233","volume":"104","author":"DA Doornbos","year":"1969","unstructured":"Doornbos DA, de Zeeuw RA (1969) The determination of the acid dissociation constants of barbiturates by an accurate method of pH measurement. Pharmaceutisch Weekbl 104:233?251","journal-title":"Pharmaceutisch Weekbl"},{"key":"CR4","doi-asserted-by":"crossref","first-page":"745","DOI":"10.1021\/jm00317a001","volume":"10","author":"C Hansch","year":"1967","unstructured":"Hansch C, Anderson SM (1967) The structure-activity relationship in barbiturates and its similarity to that in other narcotics. J Med Chem 10:745?753","journal-title":"J Med Chem"},{"key":"CR5","doi-asserted-by":"crossref","first-page":"1375","DOI":"10.1016\/0006-291X(70)90539-5","volume":"41","author":"P Hinkle","year":"1970","unstructured":"Hinkle P (1970) A model system for mitochondrial transport and respiratory control. Biochem Biophys Res Commun 41:1375?1381","journal-title":"Biochem Biophys Res Commun"},{"key":"CR6","first-page":"1988","volume":"32","author":"P Hinkle","year":"1973","unstructured":"Hinkle P (1973) Electron transfer across membranes and energy coupling. Fed Proc 32:1988?1992","journal-title":"Fed Proc"},{"key":"CR7","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1007\/BF01871925","volume":"38","author":"MJ Jackson","year":"1978","unstructured":"Jackson MJ, Airall AA (1978) Transport of heterocyclic acids across rat small intestine in vitro. J Membr Biol 38:255?269","journal-title":"J Membr Biol"},{"key":"CR8","doi-asserted-by":"crossref","first-page":"1534","DOI":"10.1248\/cpb.15.1534","volume":"15","author":"K Kakemi","year":"1967","unstructured":"Kakemi K, Arita T, Hori R, Konishi R (1967a) Absorption and excretion of drugs. XXX Absorption of barbituric acid derivatives from rat stomach. Chem Pharm Bull 15:1534?1539","journal-title":"Chem Pharm Bull"},{"key":"CR9","doi-asserted-by":"crossref","first-page":"1883","DOI":"10.1248\/cpb.15.1883","volume":"15","author":"K Kakemi","year":"1967","unstructured":"Kakemi K, Arita T, Hori R, Konishi R (1967b) Absorption and excretion of drugs. XXXII Absorption of barbituric acid derivatives from rat small intestine. Chem Pharm Bull 15:1883?1887","journal-title":"Chem Pharm Bull"},{"key":"CR10","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1248\/cpb.17.248","volume":"17","author":"K Kakemi","year":"1969","unstructured":"Kakemi K, Arita T, Hori R, Konishi R, Nishimura K (1969a) Absorption and Excretion of drugs. XXXIII The correlation between the absorption of barbituric acid derivatives from rat small intestine and their binding to the mucosa. Chem Pharm Bull 17:248?254","journal-title":"Chem Pharm Bull"},{"key":"CR11","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1248\/cpb.17.255","volume":"17","author":"K Kakemi","year":"1969","unstructured":"Kakemi K, Arita T, Hori R, Konishi R, Nishimura K, Matsui H, Nishimura T (1969b) Absorption and excretion of drugs. XXXIV An aspect of the mechanism of drug absorption from the intestinal tract in rats. Chem Pharm Bull 17:255?261","journal-title":"Chem Pharm Bull"},{"key":"CR12","doi-asserted-by":"crossref","first-page":"825","DOI":"10.1152\/physrev.1980.60.3.825","volume":"60","author":"SGA McLaughlin","year":"1980","unstructured":"McLaughlin SGA, Dilger JP (1980) Transport of protons across membranes by weak acids. Physiol Rev 60:825?863","journal-title":"Physiol Rev"},{"key":"CR13","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1038\/263253a0","volume":"263","author":"KW Miller","year":"1976","unstructured":"Miller KW, Pang KYY (1976) General anaesthetics can selectively perturb lipid bilayer membranes. Nature 263:253?255","journal-title":"Nature"},{"key":"CR14","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/0005-2736(78)90060-3","volume":"511","author":"KYY Pang","year":"1978","unstructured":"Pang KYY, Miller KW (1978) Cholesterol modulates the effect of membrane perturbers in phospholipid vesicles and biomembranes. Biochim Biophys Acta 511:1?9","journal-title":"Biochim Biophys Acta"},{"key":"CR15","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1007\/BF01066019","volume":"3","author":"JM Pl\u00e1-Delfina","year":"1975","unstructured":"Pl\u00e1-Delfina JM, Moreno J, Duran J, del Pozo A (1975) Calculation of the gastric absorption rate constants of 5-substituted barbiturates through the Rm values or substituent ?Rm constants in reversedphase partition chromatography. J Pharmacokinet Biopharm 3:115?141","journal-title":"J Pharmacokinet Biopharm"},{"key":"CR16","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1097\/00000542-197705000-00003","volume":"46","author":"PH Rosenberg","year":"1977","unstructured":"Rosenberg PH, Jansson SE, Gripenberg J (1977) Effects of halothane, thiopental and lidocane on fluidity of synaptic plasma membranes and artificial phospholipid membranes. Anaesthesiology 46:322?326","journal-title":"Anaesthesiology"},{"key":"CR17","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1007\/BF00505661","volume":"316","author":"PG Ruifrok","year":"1981","unstructured":"Ruifrok PG, Meijer DKF (1981) Transport of organic ions through lipid bilayers. Naunyn-Schmiedeberg's Arch Pharmacol 316:266?272","journal-title":"Naunyn-Schmiedeberg's Arch Pharmacol"},{"key":"CR18","first-page":"283","volume":"126","author":"LS Schanker","year":"1959","unstructured":"Schanker LS (1959) Absorption of drugs from the rat colon. J Pharmacol Exp Ther 126:283?290","journal-title":"J Pharmacol Exp Ther"},{"key":"CR19","doi-asserted-by":"crossref","first-page":"400","DOI":"10.1016\/0003-9861(73)90072-6","volume":"154","author":"SP Verma","year":"1973","unstructured":"Verma SP, Schneider H, Smith ICP (1973) Organizational changes in phospholipid multibilayers induced by uncouplers of oxidative phosphorylation: a spin label study. Arch Biochem Biophys 154:400?406","journal-title":"Arch Biochem Biophys"}],"container-title":["Naunyn-Schmiedeberg's Archives of Pharmacology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF00495863.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/BF00495863\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF00495863","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,4,4]],"date-time":"2019-04-04T16:29:32Z","timestamp":1554395372000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/BF00495863"}},"subtitle":["The barbiturates"],"short-title":[],"issued":{"date-parts":[[1982]]},"references-count":19,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1982]]}},"alternative-id":["BF00495863"],"URL":"https:\/\/doi.org\/10.1007\/bf00495863","relation":{},"ISSN":["0028-1298","1432-1912"],"issn-type":[{"value":"0028-1298","type":"print"},{"value":"1432-1912","type":"electronic"}],"subject":[],"published":{"date-parts":[[1982]]}}}