{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,10]],"date-time":"2026-01-10T09:57:48Z","timestamp":1768039068690,"version":"3.49.0"},"reference-count":44,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[1975,1,1]],"date-time":"1975-01-01T00:00:00Z","timestamp":157766400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Naunyn-Schmiedeberg's Arch. Pharmacol."],"published-print":{"date-parts":[[1975]]},"DOI":"10.1007\/bf00499949","type":"journal-article","created":{"date-parts":[[2004,11,16]],"date-time":"2004-11-16T04:27:48Z","timestamp":1100579268000},"page":"357-373","source":"Crossref","is-referenced-by-count":86,"title":["Intraaxonal and extraaxonal transport of 125I-tetanus toxin in early local tetanus"],"prefix":"10.1007","volume":"290","author":[{"given":"G.","family":"Erdmann","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.","family":"Wiegand","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H. H.","family":"Wellh\ufffdner","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"CR1","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1016\/0014-5793(74)81028-8","volume":"47","author":"T. Abe","year":"1974","unstructured":"Abe, T., Haga, T., Kurokawa, M.: Retrograde axoplasmic transport: Its continuation as anterograde transport. FEBS Lett. 47, 272?275 (1974)","journal-title":"FEBS Lett."},{"key":"CR2","volume-title":"Tetanus","author":"E. B. Adams","year":"1969","unstructured":"Adams, E. B., Laurence, D. R., Smith, J. W. C.: Tetanus. Oxford-Edinburgh: Blackwell Scientific Publications 1969"},{"key":"CR3","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1007\/BF00369291","volume":"79","author":"K. H. Andres","year":"1967","unstructured":"Andres, K. H.: \u00dcber die Feinstruktur der Arachnoidea und Dura mater von Mammalia. Z. Zellforsch. 79, 272?295 (1967)","journal-title":"Z. Zellforsch."},{"key":"CR4","first-page":"177","volume":"72","author":"B. Bizzini","year":"1974","unstructured":"Bizzini, B., Turpin, A., Raynaud, M.: Immunochimie et m\u00e9canisme d'action de la toxine t\u00e9tanique. Bull. Inst. Pasteur 72, 177?219 (1974)","journal-title":"Bull. Inst. Pasteur"},{"key":"CR5","unstructured":"Bolot, J. F., Arnaud, Ph., Charmeau, A., Fournier, G.: Etude isotopique du metabolisme des immunoglobulines antitetaniques d'origine humaine. Abstract, Fourth International Conference on Tetanus. Dakar. April 6?12, 1975"},{"key":"CR6","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/0014-2999(68)90165-9","volume":"5","author":"A. Dahlstr\u00f6m","year":"1968","unstructured":"Dahlstr\u00f6m, A.: Effect of colchicine on transport of amine storage granules in sympathetic nerves of rat. Europ. J. Pharmacol. 5, 111?113 (1968)","journal-title":"Europ. J. Pharmacol."},{"key":"CR7","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1007\/BF00499178","volume":"280","author":"W. Dimpfel","year":"1973","unstructured":"Dimpfel, W., Habermann, E.: Histoautoradiographic localisation of 125I-labeled tetanus toxin in rat spinal cord. Naunyn-Schmiedeberg's Arch. Pharmacol. 280, 177?182 (1973)","journal-title":"Naunyn-Schmiedeberg's Arch. Pharmacol."},{"key":"CR8","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1016\/0006-8993(73)90535-0","volume":"61","author":"A. Edstr\u00f6m","year":"1973","unstructured":"Edstr\u00f6m, A., Hanson, M.: Retrograde axonal transport of proteins in vitro in frog sciatic nerves. Brain Res. 61, 311?320 (1973)","journal-title":"Brain Res."},{"key":"CR9","first-page":"168","volume-title":"Principles on tetanus","author":"A. A. Fedinec","year":"1967","unstructured":"Fedinec, A. A.: Absorption and distribution of tetanus toxin in experimental animals. In: Principles on tetanus, L. Eckmann, ed., pp. 168?175. Bern-Stuttgart: H. Huber 1967"},{"key":"CR10","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1016\/0006-8993(73)90343-0","volume":"56","author":"B. R. Fink","year":"1973","unstructured":"Fink, B. R., Byers, M. R., Middaugh, M. E.: Dynamics of colchicine effects on rapid axonal transport and axonal morphology. Brain Res. 56, 299?311 (1973)","journal-title":"Brain Res."},{"key":"CR11","unstructured":"Gardner, D. P., Fedinec, A. A.: Localization of tetanus toxin in the rat sciatic nerve. Abstract, Fourth International Conference on Tetanus. Dakar. April 6?12, 1975"},{"key":"CR12","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/BF00997110","volume":"267","author":"E. Habermann","year":"1970","unstructured":"Habermann, E.: Pharmakokinetische Besonderheiten des Tetanustoxins und ihre Beziehungen zur Pathogenese des lokalen bzw. generalisierten Tetanus. Naunyn-Schmiedebergs Arch. Pharmak. 267, 1?19 (1970)","journal-title":"Naunyn-Schmiedebergs Arch. Pharmak."},{"key":"CR13","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1007\/BF00498795","volume":"272","author":"E. Habermann","year":"1972","unstructured":"Habermann, E.: Distribution of 125I-tetanus toxin and 125I-toxoid in rats with local tetanus as influenced by antitoxin. Naunyn-Schmiedeberg's Arch. Pharmacol. 272, 75?88 (1972)","journal-title":"Naunyn-Schmiedeberg's Arch. Pharmacol."},{"key":"CR14","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1007\/BF00499889","volume":"276","author":"E. Habermann","year":"1973","unstructured":"Habermann, E., Dimpfel, W., R\u00e4ker, K. O.: Interaction of labelled tetanus toxin with substructures of rat spinal cord in vivo. Naunyn-Schmiedeberg's Arch. Pharmacol. 276, 361?374 (1973)","journal-title":"Naunyn-Schmiedeberg's Arch. Pharmacol."},{"key":"CR15","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/0006-8993(74)90536-8","volume":"68","author":"I. A. Hendry","year":"1974","unstructured":"Hendry, I. A., St\u00f6ckel, K., Thoenen, H., Iversen, L. L.: The retrograde axonal transport of nerve growth factor. Brain Res. 68, 103?121 (1974)","journal-title":"Brain Res."},{"key":"CR16","first-page":"69","volume-title":"Microbial toxins","author":"W. E. Heyningen van","year":"1971","unstructured":"van Heyningen, W. E., Mellanby, J. H.: Tetanus toxin. In: Microbial toxins, S. Kadis, T. C. Montie and S. J. Ajl, eds., Vol. II A, pp. 69?108. New York-London: Academic Press 1971"},{"key":"CR17","doi-asserted-by":"crossref","first-page":"460","DOI":"10.1007\/BF00455243","volume":"119","author":"T. H\u00f6kfelt","year":"1971","unstructured":"H\u00f6kfelt, T., Dahlstr\u00f6m, A.: Effects of two mitosis inhibitors (colchicine and vinblastine) on the distribution and axonal transport of noradrenaline storage particles, studied by fluorescence and electron microscopy. Z. Zellforsch. 119, 460?482 (1971)","journal-title":"Z. Zellforsch."},{"key":"CR18","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1007\/BF00687594","volume":"24","author":"L. E. King","year":"1973","unstructured":"King, L. E., Fedinec, A. A.: Distribution of tetanus toxin in rat peripheral nerve trunks during the development of local tetanus. Acta neuropath. (Berl.) 24, 244?255 (1973)","journal-title":"Acta neuropath. (Berl.)"},{"key":"CR19","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1007\/BF00336529","volume":"108","author":"H. Klemm","year":"1970","unstructured":"Klemm, H.: Das Perineurium als Diffusionsbarriere gegen\u00fcber Peroxydase bei epi- und endoneuraler Applikation. Z. Zellforsch. 108, 431?445 (1970)","journal-title":"Z. Zellforsch."},{"key":"CR20","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1007\/BF00684740","volume":"17","author":"K. Kristensson","year":"1971","unstructured":"Kristensson, K., Lycke, E., Sj\u00f6strand, J.: Spread of Herpes simplex virus in peripheral nerves. Acta neuropath. (Berl.) 17, 44?53 (1971)","journal-title":"Acta neuropath. (Berl.)"},{"key":"CR21","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/0006-8993(72)90224-7","volume":"45","author":"K. Kristensson","year":"1972","unstructured":"Kristensson, K., Sj\u00f6strand, J.: Retrograde transport of protein tracer in the rabbit hypoglossal nerve during regeneration. Brain Res. 45, 175?182 (1972)","journal-title":"Brain Res."},{"key":"CR22","volume-title":"Tetanus","author":"G. N. Kryzhanovsky","year":"1966","unstructured":"Kryzhanovsky, G. N.: Tetanus. Moscow: State Publish. House ?Medicine?, 1966 (in Russian)"},{"key":"CR23","first-page":"155","volume-title":"Principles on tetanus","author":"G. N. Kryzhanovsky","year":"1967","unstructured":"Kryzhanovsky, G. N.: The neural pathway of toxin. In: Principles on tetanus, L. Eckmann, ed., pp. 155?168. Bern-Stuttgart: H. Huber 1967"},{"key":"CR24","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1007\/BF00499880","volume":"276","author":"G. N. Kryzhanovsky","year":"1973","unstructured":"Kryzhanovsky, G. N.: The mechanism of action of tetanus toxin: Effect on synaptic processes and some particular features of toxin binding by the nervous tissue. Naunyn-Schmiedeberg's Arch. Pharmacol. 276, 247?270 (1973)","journal-title":"Naunyn-Schmiedeberg's Arch. Pharmacol."},{"key":"CR25","first-page":"63","volume":"9","author":"G. N. Kryzhanovsky","year":"1970","unstructured":"Kryzhanovsky, G. N., Alekseev, L. P., Rozanov, A. Ja.: Antitoxin neutralization of tetanus toxin bound with the cerebral substance. Bull. exp. Biol. Med. (Russ.) 9, 63?65 (1970)","journal-title":"Bull. exp. Biol. Med. (Russ.)"},{"key":"CR26","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1007\/BF00805372","volume":"75","author":"G. N. Kryzhanovsky","year":"1973","unstructured":"Kryzhanovsky, G. N., Grafova, V. N., Tumanov, V. P., Vtyurin, B. V.: Ultrastructural changes in the spinal cord in tetanus intoxication. Bull. exp. Biol. Med. (Russ.) 75, 100?105 (1973)","journal-title":"Bull. exp. Biol. Med. (Russ.)"},{"key":"CR27","first-page":"38","volume":"5","author":"G. N. Kryzhanovsky","year":"1971","unstructured":"Kryzhanovsky, G. N., Krasnova, N. M.: Intracisternal introduction of tetanus antitoxin in experimental tetanus intoxication. Bull. exp. Biol. Med. (Russ.) 5, 38?42 (1971)","journal-title":"Bull. exp. Biol. Med. (Russ.)"},{"key":"CR28","doi-asserted-by":"crossref","first-page":"1370","DOI":"10.1007\/BF00785298","volume":"52","author":"G. N. Kryzhanovsky","year":"1961","unstructured":"Kryzhanovsky, G. N., Pevnitsky, L. A., Grafova, V. N., Polgar, A. A.: Routes of entrance of tetanus toxin into the central nervous system and certain questions in the pathogenesis of experimental tetanus. IV. On the pathogenesis of ascending and descending tetanus. Bull. exp. Biol. Med. (Engl. Transl.) 52, 1370?1377 (1961a)","journal-title":"Bull. exp. Biol. Med. (Engl. Transl.)"},{"key":"CR29","doi-asserted-by":"crossref","first-page":"894","DOI":"10.1007\/BF00786703","volume":"52","author":"G. N. Kryzhanovsky","year":"1961","unstructured":"Kryzhanovsky, G. N., Pevnitsky, L. A., Grafova, V. N., Polgar, A. A.: Routes of entrance of tetanus toxin into the central nervous system and some problems connected with the pathogenesis of experimental tetanus. II. Experiments on mice, guinea pigs, rabbits, and cats. Bull. exp. Biol. Med. (Engl. Transl.) 52, 894?898 (1961b)","journal-title":"Bull. exp. Biol. Med. (Engl. Transl.)"},{"key":"CR30","doi-asserted-by":"crossref","first-page":"286","DOI":"10.1002\/cpt196782286","volume":"8","author":"C. Lamanna","year":"1967","unstructured":"Lamanna, C., Carr, C. J.: The botulinal, tetanal and enterostaphylococcal toxins: A review. Clin. Pharmacol. Ther. 8, 286?332 (1967)","journal-title":"Clin. Pharmacol. Ther."},{"key":"CR31","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1002\/cpt19634136","volume":"4","author":"D. R. Laurence","year":"1963","unstructured":"Laurence, D. R., Webster, R. A.: Pathologic physiology, pharmacology and therapeutics of tetanus. Clin. Pharmacol. Ther. 4, 36?72 (1963)","journal-title":"Clin. Pharmacol. Ther."},{"key":"CR32","doi-asserted-by":"crossref","first-page":"845","DOI":"10.1111\/j.1471-4159.1969.tb08972.x","volume":"16","author":"S. Ochs","year":"1969","unstructured":"Ochs, S., Johnson, J.: Fast and slow phases of axoplasmic flow in ventral root nerve fibres. J. Neurochem. 16, 845?853 (1969)","journal-title":"J. Neurochem."},{"key":"CR33","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1016\/0006-8993(74)90638-6","volume":"77","author":"M. T. Price","year":"1974","unstructured":"Price, M. T.: The effects of colchicine and lumicolchicine on the rapid phase of axonal transport in the rabbit visual system. Brain Res. 77, 497?501 (1974)","journal-title":"Brain Res."},{"key":"CR34","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1159\/000127681","volume":"5","author":"L.-O. Ronnevi","year":"1973","unstructured":"Ronnevi, L.-O., Bystr\u00f6m, J., Eriksson, E., Ottova, L.: Quantitative distribution of tetanus toxin in peripheral nerves and central nervous system. Europ. Surg. Res. 5, 401?413 (1973)","journal-title":"Europ. Surg. Res."},{"key":"CR35","doi-asserted-by":"crossref","first-page":"526","DOI":"10.1016\/0006-8993(74)90828-2","volume":"76","author":"P. Schubert","year":"1974","unstructured":"Schubert, P., Kreutzberg, G. W.: Axonal transport of adenosine and uridine derivatives and transfer to postsynaptic neurons. Brain Res. 76, 526?530 (1974)","journal-title":"Brain Res."},{"key":"CR36","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1007\/BF00687240","volume":"27","author":"B. S\u00f6derfeldt","year":"1974","unstructured":"S\u00f6derfeldt, B.: The perineurium as a diffusion barrier to protein tracers. Acta neuropath. (Berl.) 27, 55?60 (1974)","journal-title":"Acta neuropath. (Berl.)"},{"key":"CR37","doi-asserted-by":"crossref","unstructured":"Stoeckel, K., Schwab, M., Thoenen, H.: Comparison between retrograde axonal transport of nerve growth factor and tetanus toxin in motor, sensory and adrenergic neurons. Brain Res. (in press, 1975)","DOI":"10.1016\/0006-8993(75)90129-8"},{"key":"CR38","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1016\/0014-4886(74)90062-4","volume":"44","author":"J. M. Tarlov","year":"1974","unstructured":"Tarlov, J. M.: Rigidity and primary motoneuron damage in tetanus. Exp. Neurol. 44, 246?254 (1974)","journal-title":"Exp. Neurol."},{"key":"CR39","doi-asserted-by":"crossref","first-page":"580","DOI":"10.1212\/WNL.23.6.580","volume":"23","author":"J. M. Tarlov","year":"1973","unstructured":"Tarlov, J. M., Ling, H., Gamada, H.: Neuronal pathology in experimental local tetanus: Clinical implications. Neurology (Minneap.) 23, 580?591 (1973)","journal-title":"Neurology (Minneap.)"},{"key":"CR40","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1007\/BF00499890","volume":"276","author":"H. H. Wellh\u00f6ner","year":"1973","unstructured":"Wellh\u00f6ner, H. H., Hensel, B., Seib, U. C.: Local tetanus in cats: Neuropharmacokinetics of 125I-tetanus toxin. Naunyn-Schmiedeberg's Arch. Pharmacol. 276, 375?386 (1973a)","journal-title":"Naunyn-Schmiedeberg's Arch. Pharmacol."},{"key":"CR41","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1007\/BF00499891","volume":"276","author":"H. H. Wellh\u00f6ner","year":"1973","unstructured":"Wellh\u00f6ner, H. H., Seib, U. C., Hensel, B.: Local tetanus in cats: The influence of neuromuscular activity on spinal distribution of 125I-labelled tetanus toxin. Naunyn-Schmiedeberg's Arch. Pharmacol. 276, 387?394 (1973b)","journal-title":"Naunyn-Schmiedeberg's Arch. Pharmacol."},{"key":"CR42","first-page":"158","volume":"33","author":"L. Wilson","year":"1974","unstructured":"Wilson, L., Bamburg, J. R., Mizel, S. B., Grisham, L. M., Creswell, K. M.: Interaction of drugs with microtubule proteins. Fed. Proc. 33, 158?166 (1974)","journal-title":"Fed. Proc."},{"key":"CR43","first-page":"414","volume":"7","author":"G. P. Wright","year":"1955","unstructured":"Wright, G. P.: The neurotoxins of clostridium botulinum and clostridium tetani. Pharmacol. Rev. 7, 414?465 (1955)","journal-title":"Pharmacol. Rev."},{"key":"CR44","first-page":"210","volume-title":"Neurosciences Research","author":"S. J. Zacks","year":"1970","unstructured":"Zacks, S. J., Sheff, M. F.: Pathobiological aspects of the action of tetanal toxin in the nervous system and skeletal muscle. In: Neurosciences Research, S. Ehrenpreis and O. C. Solnitzky, eds., Vol. III, pp. 210?287. New York: Academic Press 1970"}],"container-title":["Naunyn-Schmiedeberg's Archives of Pharmacology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF00499949.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/BF00499949\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF00499949","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,6,28]],"date-time":"2021-06-28T16:50:48Z","timestamp":1624899048000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/BF00499949"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1975]]},"references-count":44,"journal-issue":{"issue":"4","published-print":{"date-parts":[[1975]]}},"alternative-id":["BF00499949"],"URL":"https:\/\/doi.org\/10.1007\/bf00499949","relation":{},"ISSN":["0028-1298","1432-1912"],"issn-type":[{"value":"0028-1298","type":"print"},{"value":"1432-1912","type":"electronic"}],"subject":[],"published":{"date-parts":[[1975]]}}}