{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,3]],"date-time":"2025-11-03T08:57:30Z","timestamp":1762160250018},"reference-count":17,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[1974,1,1]],"date-time":"1974-01-01T00:00:00Z","timestamp":126230400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Naunyn-Schmiedeberg's Arch. Pharmacol."],"published-print":{"date-parts":[[1974]]},"DOI":"10.1007\/bf00500985","type":"journal-article","created":{"date-parts":[[2004,11,17]],"date-time":"2004-11-17T05:09:52Z","timestamp":1100668192000},"page":"367-377","source":"Crossref","is-referenced-by-count":16,"title":["The site of action of the optical isomers of 1-methyl-5-phenyl-5-propyl barbituric acid"],"prefix":"10.1007","volume":"282","author":[{"given":"W.","family":"Grossmann","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"I.","family":"Jurna","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Theres","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"CR1","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1152\/jn.1947.10.5.349","volume":"10","author":"C. McC. Brooks","year":"1947","unstructured":"Brooks, C. McC., Eccles, J. C.: A study of the effects of anesthesia and asphyxia on the monosynaptic pathway through the spinal cord. J. Neurophysiol. 10, 349?360 (1947)","journal-title":"J. Neurophysiol."},{"key":"CR2","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1007\/BF00501159","volume":"277","author":"H. P. B\ufffdch","year":"1973","unstructured":"B\ufffdch, H. P., Schneider-Affeld, F., Rummel, W.: Stereochemical dependence of pharmacological activity in a series of optically active N-methylated barbiturates. Naunyn-Schmiedeberg's Arch. Pharmacol. 277, 191?198 (1973)","journal-title":"Naunyn-Schmiedeberg's Arch. Pharmacol."},{"key":"CR3","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1002\/jhet.5570060210","volume":"6","author":"C. E. Cook","year":"1969","unstructured":"Cook, C. E., Tallent, C. R.: Synthesis of R-S-2?-pentyl barbituric acid derivatives of high optical purity. J. Heterocyclic Chem. 6, 203?206 (1969)","journal-title":"J. Heterocyclic Chem."},{"key":"CR4","first-page":"692","volume":"175","author":"H. Downes","year":"1970","unstructured":"Downes, H., Perry, R. S., Ostlund, R. E., Karler, R.: A study of the excitatory effects of barbiturates. J. Pharmacol. exp. Ther. 175, 692?699 (1970)","journal-title":"J. Pharmacol. exp. Ther."},{"key":"CR5","first-page":"283","volume":"168","author":"H. Downes","year":"1969","unstructured":"Downes, H., Williams, J. K.: Effects of a convulsant barbiturate on the spinal monosynaptic pathway. J. Pharmacol. exp. Ther. 168, 283?289 (1969)","journal-title":"J. Pharmacol. exp. Ther."},{"key":"CR6","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1152\/jn.1946.9.2.87","volume":"9","author":"J. C. Eccles","year":"1946","unstructured":"Eccles, J. C.: Synaptic potentials of motoneurones. J. Neurophysiol. 9, 87?120 (1946)","journal-title":"J. Neurophysiol."},{"key":"CR7","first-page":"443","volume":"27","author":"J. Knabe","year":"1972","unstructured":"Knabe, J., Junginger, H.: Synthese und Konfiguration weiterer optisch aktiver N-Methylbarbiturate. Pharmazie 27, 443?447 (1972)","journal-title":"Pharmazie"},{"key":"CR8","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1002\/ardp.19652980102","volume":"298","author":"J. Knabe","year":"1965","unstructured":"Knabe, J., Kr\ufffduter, R.: Spaltung von Hexobarbital (Evipan\ufffd) in optische Antipoden. Arch. Pharm. (Weinheim) 298, 1?4 (1965)","journal-title":"Arch. Pharm. (Weinheim)"},{"key":"CR9","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1002\/ardp.19662990308","volume":"299","author":"J. Knabe","year":"1966","unstructured":"Knabe, J., Philipson, K.: Spaltung einiger racemischer Barbitale in optische Antipoden. Arch. Pharm. (Weinheim) 299, 231?242 (1966)","journal-title":"Arch. Pharm. (Weinheim)"},{"key":"CR10","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1002\/anie.196804632","volume":"7","author":"J. Knabe","year":"1968","unstructured":"Knabe, J., Strauss, D.: Synthesis of both hexobarbital enantiomers and of (+)-thiohexobarbital from (+)-methyl-2-cyano-2-(1-cyclohexenyl)-propionate. Angew. Chem. int. Ed. Engl. 7, 463?464 (1968)","journal-title":"Angew. Chem. int. Ed. Engl."},{"key":"CR11","first-page":"522","volume":"23","author":"J. Knabe","year":"1968","unstructured":"Knabe, J., Strauss, D., Urbahn, C.: Die optischen Antipoden von 5-\ufffdthyl-5-norhexobarbital. Pharmazie 23, 522 (1968)","journal-title":"Pharmazie"},{"key":"CR12","first-page":"245","volume":"132","author":"J. Lewin","year":"1961","unstructured":"Lewin, J., Esplin, D. W.: Analysis of the spinal excitatory action of pentylenetetrazol. J. Pharmacol. exp. Ther. 132, 245?250 (1961)","journal-title":"J. Pharmacol. exp. Ther."},{"key":"CR13","doi-asserted-by":"crossref","first-page":"408","DOI":"10.1152\/jn.1964.27.3.408","volume":"27","author":"Y. L\ufffdyning","year":"1964","unstructured":"L\ufffdyning, Y., Oshima, T., Yokota, T.: Site of action of thiamylal sodium on the monosynaptic spinal reflex pathway in cats. J. Neurophysiol. 27, 408?428 (1964)","journal-title":"J. Neurophysiol."},{"key":"CR14","first-page":"496","volume":"16","author":"W. Rummel","year":"1967","unstructured":"Rummel, W., Brandenburger, U., B\ufffdch, H.: Versuche zur Aufkl\ufffdrung der Ursachen der unterschiedlichen narkotischen Wirksamkeit von (+)- und (?)-Hexobarbital. Med. Pharmacol. exp. 16, 496?504 (1967)","journal-title":"Med. Pharmacol. exp."},{"key":"CR15","first-page":"19","volume":"140","author":"G. G. Somjen","year":"1963","unstructured":"Somjen, G. G., Gill, M.: The mechanism of the blockade of synaptic transmission in the mammalian spinal cord by diethyl ether and by thiopental. J. Pharmacol. exp. Ther. 140, 19?30 (1963)","journal-title":"J. Pharmacol. exp. Ther."},{"key":"CR16","doi-asserted-by":"crossref","first-page":"1781","DOI":"10.1016\/0024-3205(66)90054-3","volume":"5","author":"G. Wahlstr\ufffdm","year":"1966","unstructured":"Wahlstr\ufffdm, G.: Differences in anesthetic properties between the optical antipodes of hexobarbital in the rat. Life Sci. 5, 1781?1790 (1966)","journal-title":"Life Sci."},{"key":"CR17","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1113\/jphysiol.1969.sp008898","volume":"204","author":"J. N. Weakly","year":"1969","unstructured":"Weakly, J. N.: Effect of barbiturates on ?quantal? synaptic transmission in spinal motoneurones. J. Physiol. (Lond.) 204, 63?77 (1969)","journal-title":"J. Physiol. (Lond.)"}],"container-title":["Naunyn-Schmiedeberg's Archives of Pharmacology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF00500985.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/BF00500985\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF00500985","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,4,4]],"date-time":"2019-04-04T18:15:37Z","timestamp":1554401737000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/BF00500985"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1974]]},"references-count":17,"journal-issue":{"issue":"4","published-print":{"date-parts":[[1974]]}},"alternative-id":["BF00500985"],"URL":"https:\/\/doi.org\/10.1007\/bf00500985","relation":{},"ISSN":["0028-1298","1432-1912"],"issn-type":[{"value":"0028-1298","type":"print"},{"value":"1432-1912","type":"electronic"}],"subject":[],"published":{"date-parts":[[1974]]}}}