{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,21]],"date-time":"2026-02-21T02:51:57Z","timestamp":1771642317709,"version":"3.50.1"},"reference-count":42,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[1980,9,1]],"date-time":"1980-09-01T00:00:00Z","timestamp":336614400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Naunyn-Schmiedeberg's Arch. Pharmacol."],"published-print":{"date-parts":[[1980,9]]},"DOI":"10.1007\/bf00505740","type":"journal-article","created":{"date-parts":[[2004,11,17]],"date-time":"2004-11-17T09:01:10Z","timestamp":1100682070000},"page":"243-247","source":"Crossref","is-referenced-by-count":27,"title":["Influence of vasoactive intestinal polypeptide on net water flux and cyclic adenosine 3?,5?-monophosphate formation in the rat jejunum"],"prefix":"10.1007","volume":"313","author":[{"given":"E.","family":"Beubler","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"CR1","doi-asserted-by":"crossref","first-page":"474","DOI":"10.1016\/0304-4165(78)90321-5","volume":"544","author":"B. Amiranoff","year":"1978","unstructured":"Amiranoff, B., Laburthe, M., Dupont, C., Rosselin, G.: Characterization of a vasoactive intestinal peptide-sensitive adenylate cyclase in rat intestinal epithelial cell membranes. Biochim. Biophys. Acta 544, 474?481 (1978)","journal-title":"Biochim. Biophys. Acta"},{"key":"CR2","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1126\/science.174.4007.422","volume":"174","author":"G. O. Barbezat","year":"1971","unstructured":"Barbezat, G. O., Grossman, M. I.: Intestinal secretion: stimulation by peptides. Science 174, 422?423 (1971)","journal-title":"Science"},{"key":"CR3","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1007\/BF00497010","volume":"305","author":"E. Beubler","year":"1978","unstructured":"Beubler, E., Juan, H.: PGE-release, blood flow and transmucosal water movement after mechanical stimulation of the rat jejunal mucosa. Naunyn-Schmiedeberg's Arch. Pharmacol. 305, 91?95 (1978)","journal-title":"Naunyn-Schmiedeberg's Arch. Pharmacol."},{"key":"CR4","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1007\/BF00498980","volume":"306","author":"E. Beubler","year":"1979","unstructured":"Beubler, E., Lembeck, F.: Inhibition of stimulated fluid secretion in the rat small and large intestine by opiate agonists. Naunyn-Schmiedeberg's Arch. Pharmacol. 306, 113?118 (1979)","journal-title":"Naunyn-Schmiedeberg's Arch. Pharmacol."},{"key":"CR5","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1111\/j.1476-5381.1980.tb14566.x","volume":"68","author":"E. Beubler","year":"1980","unstructured":"Beubler, E., Lembeck, F.: Inhibition by morphine of prostaglandin E1-stimulated secretion and cyclic adenosine 3?,5?-monophosphate formation in the rat jejunum in vivo. Br. J. Pharmacol. 68, 513?518 (1980)","journal-title":"Br. J. Pharmacol."},{"key":"CR6","doi-asserted-by":"crossref","unstructured":"Bloom, S. R., Polak, J. M., Pearse, A. G. E.: Vasoactive intestinal peptide and watery-diarrhoea syndrome. Lancet 1973 II, 14?16","DOI":"10.1016\/S0140-6736(73)91947-8"},{"key":"CR7","first-page":"365","volume":"25","author":"S. R. Bloom","year":"1978","unstructured":"Bloom, S. R., Mitchell, S. J., Greenberg, G. R., Christofides, N., Domschke, W., Domschke, S., Mitznegg, P., Demling, L.: Release of VIP, secretin and motilin after duodenal acidification in man. Acta Hepato-Gastroenterol. 25, 365?369 (1978)","journal-title":"Acta Hepato-Gastroenterol."},{"key":"CR8","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1016\/0024-3205(79)90281-9","volume":"24","author":"C Borghi","year":"1979","unstructured":"Borghi, C, Nicosia, S., Giachetti, A., Said, S. I.: Vasoactive intestinal polypeptide (VIP) stimulates adenylate cyclase in selected areas of the rat brain. Life Sci 24, 65?70 (1979)","journal-title":"Life Sci"},{"key":"CR9","first-page":"136","volume":"70","author":"E. J. Burbige","year":"1978","unstructured":"Burbige, E. J., Manning, R. J., Belber, J. P.: Watery diarrhea syndrome with elevated levels of vasoactive polypeptide associated with pancreatitis and pancreatic pseudocyst. Am. J. Gastroenterol. 70, 136?141 (1978)","journal-title":"Am. J. Gastroenterol."},{"key":"CR10","doi-asserted-by":"crossref","unstructured":"Bryant, M. G., Bloom, S. R., Polak, J. M.: Possible dual role for vasoactive intestinal peptide as gastrointestinal hormone and neurotransmitter substance. Lancet 1976 I, 991","DOI":"10.1016\/S0140-6736(76)91863-8"},{"key":"CR11","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1038\/248024a0","volume":"248","author":"H. O. J. Collier","year":"1974","unstructured":"Collier, H. O. J., Roy, A. C.: Morphine-like drugs inhibit the stimulation by E prostaglandins of cyclic AMP formation by rat brain homogenate. Nature 248, 24?27 (1974)","journal-title":"Nature"},{"key":"CR12","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1111\/j.1476-5381.1978.tb07774.x","volume":"63","author":"I. M. Coupar","year":"1978","unstructured":"Coupar, I. M.: Inhibition by morphine of prostaglandin-stimulated fluid secretion in rat jejunum. Br. J. Pharmacol. 63, 57?63 (1978)","journal-title":"Br. J. Pharmacol."},{"key":"CR13","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1111\/j.1748-1716.1979.tb00111.x","volume":"105","author":"S. Eklund","year":"1979","unstructured":"Eklund, S., Jodal, M., Lundgren, O., Sj\u00f6quist, A.: Effects of vasoactive intestinal polypeptide on blood flow, motility and fluid transport in the gastrointestinal tract of the cat. Acta Physiol. Scand. 105, 461?468 (1979)","journal-title":"Acta Physiol. Scand."},{"key":"CR14","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1016\/0006-8993(79)91109-0","volume":"173","author":"P. C. Emson","year":"1979","unstructured":"Emson, P. C., Fahrenkrug, J., Spokes, E. G. S.: Vasoactive intestinal polypeptide (VIP): distribution in normal human brain and in Huntington's disease. Brain Res. 173, 174?178 (1979)","journal-title":"Brain Res."},{"key":"CR15","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1113\/jphysiol.1978.sp012391","volume":"280","author":"J. Fahrenkrug","year":"1978","unstructured":"Fahrenkrug, J., Galbo, H., Holst, J. J., Schaffalitzky de Muckadell, O. B.: Influence of the autonomic nervous system on the release of vasoactive intestinal polypeptide from the porcine gastrointestinal tract. J. Physiol. 280, 405?422 (1978a)","journal-title":"J. Physiol."},{"key":"CR16","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1113\/jphysiol.1978.sp012541","volume":"284","author":"J. Fahrenkrug","year":"1978","unstructured":"Fahrenkrug, J., Haglund, U., Jodal, M., Lundgren, O., Olbe, L., Schaffalitzky de Muckadell, O. B.: Nervous release of vasoactive intestinal polypeptide in the gastrointestinal tract of cats: possible physiological implications. J. Physiol. 284, 291?305 (1978b)","journal-title":"J. Physiol."},{"key":"CR17","doi-asserted-by":"crossref","first-page":"1445","DOI":"10.1111\/j.1471-4159.1978.tb06571.x","volume":"31","author":"J. Fahrenkrug","year":"1978","unstructured":"Fahrenkrug, J., Schaffalitzky de Muckadell, O. B.: Distribution of vasoactive intestinal polypeptide (VIP) in the porcine central nervous systems. J. Neurochem. 31, 1445?1451 (1978c)","journal-title":"J. Neurochem."},{"key":"CR18","first-page":"1505","volume":"8","author":"J. F. Grenier","year":"1979","unstructured":"Grenier, J. F., Marescaux, J., Michel, F., Sava, G., Kachelhoffer, J.: Vasoactive intestinal peptide (VIP) in the Verner-Morrison syndrome. Nouv. Presse Med. 8, 1505?1508 (1979)","journal-title":"Nouv. Presse Med."},{"key":"CR19","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1016\/0006-8993(78)90298-6","volume":"150","author":"U. Havemann","year":"1978","unstructured":"Havemann, U., Kuschinsky, K.: Effect of morphine on prostaglandin E2 (PGE2)-sensitive adenylate cyclase in corpus striatum of rats and its cellular localization by using kainic acid. Brain Res. 150, 441?445 (1978)","journal-title":"Brain Res."},{"key":"CR20","doi-asserted-by":"crossref","first-page":"1023","DOI":"10.1016\/S0016-5085(19)32761-1","volume":"67","author":"D. V. Kimberg","year":"1974","unstructured":"Kimberg, D. V.: Cyclic nucleotides and their role in gastrointestinal secretion. Gastroenterology 67, 1023?1064 (1974)","journal-title":"Gastroenterology"},{"key":"CR21","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1007\/BF00583463","volume":"361","author":"S. J. Konturek","year":"1976","unstructured":"Konturek, S. J., Dembinski, A., Thor, P., Krol, R.: Comparison of vasoactive intestinal peptide (VIP) and secretin in gastric secretion and mucosal blood flow. Pfl\u00fcgers Arch. 361, 175?181 (1976)","journal-title":"Pfl\u00fcgers Arch."},{"key":"CR22","doi-asserted-by":"crossref","first-page":"851","DOI":"10.1016\/0016-5085(78)90140-3","volume":"74","author":"S. J. Konturck","year":"1978","unstructured":"Konturck, S. J., Tasler, J., Cieszkowski, M., Jaworek, J., Coy, D. H., Schally, A. V.: Inhibition of pancreatic secretion by enkephalin and morphine in dogs. Gastroenterology 74, 851?855 (1978)","journal-title":"Gastroenterology"},{"key":"CR23","doi-asserted-by":"crossref","first-page":"1337","DOI":"10.1172\/JCI109051","volume":"61","author":"G. J. Krejs","year":"1978","unstructured":"Krejs, G. J., Barkley, R. M., Read, N. W., Fordtran, J. S.: Intestinal secretion induced by vasoactive intestinal polypeptide. J. Clin. Invest. 61, 1337?1346 (1978)","journal-title":"J. Clin. Invest."},{"key":"CR24","first-page":"2139","volume":"284","author":"M. Laburthe","year":"1977","unstructured":"Laburthe, M., Besson, J., Hui Bon Hoa, D., Rosselin, G.: Recepteurs du peptide intestinal vasoactif (VIP) dans les enterocytes: liaison specifique et stimulation de l'AMP cyclique. C. R. Acad. Sci. Paris 284, 2139?2142 (1977)","journal-title":"C. R. Acad. Sci. Paris"},{"key":"CR25","doi-asserted-by":"crossref","first-page":"3197","DOI":"10.1073\/pnas.73.9.3197","volume":"73","author":"L. I. Larsson","year":"1976","unstructured":"Larsson, L. I., Fahrenkrug, J., Schaffalitzky de Muckadell, O. B., Sundler, F., Hakanson, R., Rehfeld, J. F.: Localization of vasoactive intestinal polypeptide (VIP) to central and peripheral neurones. Proc. Natl. Acad. Sci. USA 73, 3197?3200 (1976)","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"CR26","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1007\/BF00501391","volume":"308","author":"F. Lembeck","year":"1979","unstructured":"Lembeck, F., Beubler, E.: Inhibition of PGE1 induced intestinal secretion by the synthetic enkephalin analogue FK 33-824. Naunyn-Schmiedeberg's Arch. Pharmacol. 308, 261?264 (1979)","journal-title":"Naunyn-Schmiedeberg's Arch. Pharmacol."},{"key":"CR27","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/S0021-9258(19)52451-6","volume":"193","author":"O. H. Lowry","year":"1951","unstructured":"Lowry, O. H., Rosebrough, N. J., Farr, A. L., Randall, R. J.: Protein measurement with the folin phenol reagent. J. Biol. Chem. 193, 265?275 (1951)","journal-title":"J. Biol. Chem."},{"key":"CR28","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1113\/jphysiol.1978.sp012334","volume":"279","author":"D. Mailman","year":"1978","unstructured":"Mailman, D.: Effects of vasoactive intestinal polypeptide on intestinal absorption and blood flow. J. Physiol. 279, 121?132 (1978)","journal-title":"J. Physiol."},{"key":"CR29","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1007\/BF01935976","volume":"34","author":"I. M. Modlin","year":"1978","unstructured":"Modlin, I. M., Bloom, S. R., Mitchell, S.: Plasma vasoactive intestinal polypeptide (VIP) levels and intestinal ischaemia. Experientia 34, 535?536 (1978)","journal-title":"Experientia"},{"key":"CR30","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1113\/jphysiol.1978.sp012474","volume":"282","author":"K. G. Morgan","year":"1978","unstructured":"Morgan, K. G., Schmalz, P. F., Szurszewski, J. H.: The inhibitory effects of vasoactive intestinal polypeptide on the mechanical and electrical activity of canine antral smooth muscle. J. Physiol. 282, 437?450 (1978)","journal-title":"J. Physiol."},{"key":"CR31","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1016\/0005-2736(76)90277-7","volume":"433","author":"H. Murer","year":"1976","unstructured":"Murer, H., Ammann, E., Biber, J., Hopfer, U.: The surface membrane of the small intestinal epithelial cell. I. Localization of adenyl cyclase. Biochim. Biophys. Acta 433, 509?519 (1976)","journal-title":"Biochim. Biophys. Acta"},{"key":"CR32","doi-asserted-by":"crossref","first-page":"746","DOI":"10.1016\/S0016-5085(77)80167-4","volume":"72","author":"A. G. E. Pearse","year":"1977","unstructured":"Pearse, A. G. E., Polak, J. M., Bloom, S. R.: The newer gut hormones. Cellular sources, physiology, pathology, and clinical aspects. Gastronenterology 72, 746?761 (1977)","journal-title":"Gastronenterology"},{"key":"CR33","doi-asserted-by":"crossref","first-page":"2209","DOI":"10.1016\/0006-2952(78)90079-5","volume":"27","author":"M. Quik","year":"1978","unstructured":"Quik, M., Iversen, L. L., Bloom, S. R.: Effect of vasoactive intestinal peptide (VIP) and other peptides on cAMP accumulation in rat brain. Biochem. Pharmacol. 27, 2209?2213 (1978)","journal-title":"Biochem. Pharmacol."},{"key":"CR34","doi-asserted-by":"crossref","first-page":"790","DOI":"10.1016\/S0016-5085(19)31786-X","volume":"73","author":"L. C. Racusen","year":"1977","unstructured":"Racusen, L. C., Binder, H. J.: Alteration of large intestinal electrolyte transport by vasoactive intestinal polypeptide in the rat. Gastroenterology 73, 790?796 (1977)","journal-title":"Gastroenterology"},{"key":"CR35","doi-asserted-by":"crossref","first-page":"809","DOI":"10.1016\/0090-6980(76)90189-1","volume":"11","author":"A. Robert","year":"1976","unstructured":"Robert, A., Nezamis, J. E., Lancaster, C., Hanchar, A. J., Klepper, M. S.: Enteropooling assay: a test for diarrhoea produced by prostaglandins. Prostaglandins 11, 809?828 (1976)","journal-title":"Prostaglandins"},{"key":"CR36","doi-asserted-by":"crossref","first-page":"1217","DOI":"10.1126\/science.169.3951.1217","volume":"169","author":"S. I. Said","year":"1970","unstructured":"Said, S. I., Mutt, V.: Polypeptide with broad biological activity: isolation from small intestine. Science 169, 1217?1218 (1970)","journal-title":"Science"},{"key":"CR37","doi-asserted-by":"crossref","first-page":"590","DOI":"10.1073\/pnas.72.2.590","volume":"72","author":"S. K. Sharma","year":"1975","unstructured":"Sharma, S. K., Nirenberg, M., Klee, W. A.: Morphine receptors as regulators of adenylate cyclase activity. Proc. Natl. Acad. Sci. USA 72, 590?594 (1975)","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"CR38","doi-asserted-by":"crossref","first-page":"722","DOI":"10.1016\/0016-5085(78)90251-2","volume":"74","author":"B. Simon","year":"1978","unstructured":"Simon, B., Kather, H.: Activation of human adenylate cyclase in the upper gastrointestinal tract by vasoactive intestinal polypeptide. Gastroenterology 74, 722?725 (1978)","journal-title":"Gastroenterology"},{"key":"CR39","doi-asserted-by":"crossref","first-page":"536","DOI":"10.1172\/JCI107790","volume":"54","author":"C. J. Schwartz","year":"1974","unstructured":"Schwartz, C. J., Kimberg, D. V., Sheerin, H. E., Field, M., Said, S. I.: Vasoactive intestinal peptide stimulation of adenylate cyclase and active electrolyte secretion in intestinal mucosa. J. Clin. Invest. 54, 536?544 (1974)","journal-title":"J. Clin. Invest."},{"key":"CR40","first-page":"235","volume":"142","author":"L. Thulin","year":"1976","unstructured":"Thulin, L., Hellgren, M.: Choleretic effect of vasoactive intestinal peptide. Acta Chir. Scand. 142, 235?237 (1976)","journal-title":"Acta Chir. Scand."},{"key":"CR41","doi-asserted-by":"crossref","unstructured":"Tovey, K. C., Oldham, K. G., Whelan, J. A. M.: A simple direct assay for cyclic AMP in plasma and other biological samples using an improved competitive protein binding technique. Clin. Chim. Acta, in press","DOI":"10.1016\/0009-8981(74)90133-8"},{"key":"CR42","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1038\/253120a0","volume":"253","author":"J. Traber","year":"1975","unstructured":"Traber, J., Fischer, K., Latzin, St., Hamprecht, B.: Morphine antagonises action of prostaglandin in neuroblastoma and neuroblastoma X glioma hybrid cells. Nature 253, 120?122 (1975)","journal-title":"Nature"}],"container-title":["Naunyn-Schmiedeberg's Archives of Pharmacology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF00505740.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/BF00505740\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF00505740","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,6,28]],"date-time":"2021-06-28T20:40:56Z","timestamp":1624912856000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/BF00505740"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1980,9]]},"references-count":42,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1980,9]]}},"alternative-id":["BF00505740"],"URL":"https:\/\/doi.org\/10.1007\/bf00505740","relation":{},"ISSN":["0028-1298","1432-1912"],"issn-type":[{"value":"0028-1298","type":"print"},{"value":"1432-1912","type":"electronic"}],"subject":[],"published":{"date-parts":[[1980,9]]}}}