{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,25]],"date-time":"2026-01-25T12:37:28Z","timestamp":1769344648538,"version":"3.49.0"},"reference-count":40,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[1972,1,1]],"date-time":"1972-01-01T00:00:00Z","timestamp":63072000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Virchows Arch. Abt. A Path. Anat."],"published-print":{"date-parts":[[1972]]},"DOI":"10.1007\/bf00542847","type":"journal-article","created":{"date-parts":[[2004,11,18]],"date-time":"2004-11-18T18:52:10Z","timestamp":1100803930000},"page":"199-212","source":"Crossref","is-referenced-by-count":18,"title":["The cloverleaf skull syndrome"],"prefix":"10.1007","volume":"357","author":[{"given":"E.","family":"Bonucci","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F.","family":"Nardi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"CR1","doi-asserted-by":"crossref","unstructured":"Ali, S. Y., Anderson, H. C., Sajdera, S. W.: Enzymic and electron-microscopic analysis of extracellular matrix vesicles associated with calcification in cartilage. Biochem. J. 122, 56P (1971).","DOI":"10.1042\/bj1220056Pa"},{"key":"CR2","doi-asserted-by":"crossref","first-page":"1513","DOI":"10.1073\/pnas.67.3.1513","volume":"67","author":"S. Y. Ali","year":"1970","unstructured":"Ali, S. Y., Sajdera, S. W., Anderson, H. C.: Isolation and characterization of calcifying matrix vesicles from epiphyseal cartilage. Proc. nat. Acad. Sci. (Wash.) 67, 1513?1520 (1970).","journal-title":"Proc. nat. Acad. Sci."},{"key":"CR3","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1083\/jcb.41.1.59","volume":"41","author":"H. C. Anderson","year":"1969","unstructured":"Anderson, H. C.: Vesicles associated with calcification in the matrix of epiphyseal cartilage. J. Cell Biol. 41, 59?72 (1969).","journal-title":"J. Cell Biol."},{"key":"CR4","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1111\/j.2164-0947.1970.tb02737.x","volume":"32","author":"H. C. Anderson","year":"1970","unstructured":"Anderson, H. C., Matsuzawa, T., Sajdera, S. W., Ali, S. Y.: Membranous particles in calcifying cartilage matrix. Trans. N.Y. Acad. Sci. 32, 619?630 (1970).","journal-title":"Trans. N.Y. Acad. Sci."},{"key":"CR5","first-page":"198","volume":"114","author":"C. R. Angle","year":"1967","unstructured":"Angle, C. R., McIntire, M. S., Moore, R. C.: Cloverleaf skull: Kleeblattsch\u00e4del-deformity syndrome. Amer. J. Dis. Child. 114, 198?202 (1967).","journal-title":"Amer. J. Dis. Child."},{"key":"CR6","first-page":"69","volume":"44","author":"A. Ascenzi","year":"1957","unstructured":"Ascenzi, A.: Interferenze di sviluppo tra cranio ed encefalo in un caso di acrocefalosindattilia. Riv. Antropol. 44, 69?100 (1957).","journal-title":"Riv. Antropol."},{"key":"CR7","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/S0022-5320(67)80034-0","volume":"20","author":"E. Bonucci","year":"1967","unstructured":"Bonucci, E.: Fine structure of early cartilage calcification. J. Ultrastruct. Res. 20, 33?50 (1967).","journal-title":"J. Ultrastruct. Res."},{"key":"CR8","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1007\/BF00337312","volume":"103","author":"E. Bonucci","year":"1970","unstructured":"Bonucci, E.: Fine structure and histochemistry of ?calcifying globules? in epiphyseal cartilage. Z. Zellforsch. 103, 192?217 (1970).","journal-title":"Z. Zellforsch."},{"key":"CR9","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1097\/00003086-197107000-00010","volume":"78","author":"E. Bonucci","year":"1971","unstructured":"Bonucci, E.: The locus of initial calcification in cartilage and bone. Clin. Orthop. 78, 108?139 (1971).","journal-title":"Clin. Orthop."},{"key":"CR10","first-page":"116","volume-title":"Handbuch der speziellen pathologischen Anatomie und Histologie, Bewegungsapparat","author":"L. Burkhardt","year":"1970","unstructured":"Burkhardt, L., Fisher, H.: Pathologische Anatomie des Sch\u00e4dels. In: Handbuch der speziellen pathologischen Anatomie und Histologie, Bewegungsapparat (E. Uehlinger, Hrsg.), S. 116?117. Berlin-Heidelberg-New York: Springer 1970."},{"key":"CR11","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1016\/S0022-3476(65)80314-6","volume":"67","author":"D. E. Comings","year":"1965","unstructured":"Comings, D. E.: The Kleeblattsch\u00e4del syndrome ? a grotesque form of hydrocephalus. J. Pediat. 67, 126?129 (1965).","journal-title":"J. Pediat."},{"key":"CR12","first-page":"589","volume":"118","author":"M. Feingold","year":"1969","unstructured":"Feingold, M., O'Connor, J. F., Berkman, M., Darling, D. B.: Kleeblattsch\u00e4del syndrome. Amer. J. Dis. Child. 118, 589?594 (1969).","journal-title":"Amer. J. Dis. Child."},{"key":"CR13","first-page":"488","volume":"7","author":"G. G\u00f6thlin","year":"1971","unstructured":"G\u00f6thlin, G., Ericsson, J. L. E.: Fine structural localization of alkaline phosphomonoesterase in the fracture callus of the rat. Israel J. med. Sci. 7, 488?490 (1971).","journal-title":"Israel J. med. Sci."},{"key":"CR14","first-page":"439","volume":"14","author":"K. Holterm\u00fcller","year":"1960","unstructured":"Holterm\u00fcller, K., Wiedemann, H.-R.: Kleeblattsch\u00e4del-Syndrom. Med. Mschr. 14, 439?446 (1960).","journal-title":"Med. Mschr."},{"key":"CR15","first-page":"208","volume":"13","author":"I. Kimura","year":"1969","unstructured":"Kimura, I.: Observations on the fine structure of the growth plate in hypophysectomized rabbits and thyro-parathyroidectomized rabbits. Yonago Acta med. 13, 208?227 (1969).","journal-title":"Yonago Acta med."},{"key":"CR16","first-page":"23","volume":"45","author":"G. Liebaldt","year":"1964","unstructured":"Liebaldt, G.: Das ?Kleeblatt?-Sch\u00e4del-Syndrom, als Beitrag zur formalen Genese der Entwicklungsst\u00f6rungen des Sch\u00e4deldaches. Ergebn. allg. Path. path. Anat. 45, 23?28 (1964).","journal-title":"Ergebn. allg. Path. path. Anat."},{"key":"CR17","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/B978-1-4831-6755-8.50008-5","volume":"1","author":"D. A. Lowther","year":"1963","unstructured":"Lowther, D. A.: Chemical aspects of collagen fibrillogenesis. Int. Rev. Connect. Tiss. Res. 1, 63?125 (1963).","journal-title":"Int. Rev. Connect. Tiss. Res."},{"key":"CR18","first-page":"1135","volume-title":"Chemistry and molecular biology of the intercellular matrix","author":"D. A. Lowther","year":"1970","unstructured":"Lowther, D. A., Toole, B. P., Herrington, A. C.: Interaction of proteoglycans with tropocollagen. In: Chemistry and molecular biology of the intercellular matrix (E. A. Balazs, ed.), vol. 2, p. 1135. London-New York: Academic Press 1970."},{"key":"CR19","first-page":"2519","volume":"75","author":"P. Maroteaux","year":"1967","unstructured":"Maroteaux, P., Lamy, M., Robert, J.-M.: Le nanisme thanatophore. Presse m\u00e9d. 75, 2519?2524 (1967).","journal-title":"Presse m\u00e9d."},{"key":"CR20","doi-asserted-by":"crossref","first-page":"801","DOI":"10.1177\/19.12.801","volume":"19","author":"T. Matsuzawa","year":"1971","unstructured":"Matsuzawa, T., Anderson, H. C.: Phosphatases of epiphyseal cartilage studied by electron microscopic cytochemical methods. J. Histochem. Cytochem. 19, 801?808 (1971).","journal-title":"J. Histochem. Cytochem."},{"key":"CR21","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1083\/jcb.39.1.43","volume":"39","author":"V. J. Matukas","year":"1968","unstructured":"Matukas, V. J., Krikos, G. A.: Evidence for changes in protein polysaccharide associated with the onset of calcification in cartilage. J. Cell Biol. 39, 43?48 (1968).","journal-title":"J. Cell Biol."},{"key":"CR22","volume-title":"Electron microscopy. Fifth Intern. Congr. on Electron Microscopy, vol. 2","author":"G. Millonig","year":"1962","unstructured":"Millonig, G.: Further observations on a phosphate buffer for osmium solutions in fixation. In: Electron microscopy. Fifth Intern. Congr. on Electron Microscopy, vol. 2, p. P-8. New York-London: Academic Press 1962."},{"key":"CR23","first-page":"972","volume":"50","author":"P. Moscatelli","year":"1968","unstructured":"Moscatelli, P., Gilli, G., Perfumo, F.: Su un raro caso di sinostosi intra-uterina delle suture coronarie e lambdoidee: suoi possibili rapporti con la sindrome di Holterm\u00fcller e Wiedemann. Clin. Pediat. 50, 972?978 (1968).","journal-title":"Clin. Pediat."},{"key":"CR24","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1159\/000141479","volume":"37","author":"L. Moss","year":"1959","unstructured":"Moss, L.: The pathogenesis of premature synostosis in man. Acta anat. (Basel) 37, 351?371 (1959).","journal-title":"Acta anat."},{"key":"CR25","doi-asserted-by":"crossref","first-page":"478","DOI":"10.1007\/BF02801272","volume":"37","author":"P. L. Nawalkha","year":"1970","unstructured":"Nawalkha, P. L., Mangal, H. N.: Kleeblattsch\u00e4del deformity syndrome. Indian J. Pediat. 37, 478?480 (1970).","journal-title":"Indian J. Pediat."},{"key":"CR26","doi-asserted-by":"crossref","first-page":"656","DOI":"10.1136\/adc.46.249.656","volume":"46","author":"M. W. Partington","year":"1971","unstructured":"Partington, M. W., Gonzales-Crussi, F., Khakee, S. G., Wollin, D. G.: Cloverleaf skull and thanatophoric dwarfism. Report of four cases, two in the same sibship. Arch. Dis. Childh. 46, 656?664 (1971).","journal-title":"Arch. Dis. Childh."},{"key":"CR27","doi-asserted-by":"crossref","first-page":"701","DOI":"10.2106\/00004623-197052040-00004","volume":"A 52","author":"I. V. Ponseti","year":"1970","unstructured":"Ponseti, I. V.: Skeletal growth in achondroplasia. J. Bone Jt Surg. A 52, 701?716 (1970).","journal-title":"J. Bone Jt Surg."},{"key":"CR28","volume-title":"Pathology of the fetus and the newborn","author":"E. L. Potter","year":"1953","unstructured":"Potter, E. L.: Pathology of the fetus and the newborn. Chicago: Year Book Publishers 1953."},{"key":"CR29","first-page":"114","volume":"B 7","author":"U. N. Riede","year":"1971","unstructured":"Riede, U. N., Villiger, W., Schenk, R. K.: Ultrastrukturelle Untersuchung der Epiphysenfuge rachitischer Ratten nach Darstellung der Mucopolysaccharide mit Ruthenium-rot. Virchows Arch. Abt. B 7, 114?125 (1971).","journal-title":"Virchows Arch. Abt."},{"key":"CR30","doi-asserted-by":"crossref","first-page":"728","DOI":"10.1056\/NEJM197010012831404","volume":"283","author":"D. L. Rimoin","year":"1970","unstructured":"Rimoin, D. L., Hughes, G. N., Kaufman, R. L., Rosenthal, R. E., McAlister, W. H., Silberberg, R.: Endochondral ossification in achondroplastic dwarfism. New Engl. J. Med. 283, 728?735 (1970).","journal-title":"New Engl. J. Med."},{"key":"CR31","volume-title":"Dynamic calcification of bone dysplasias","author":"P. Rubin","year":"1964","unstructured":"Rubin, P.: Dynamic calcification of bone dysplasias. Chicago: Year Book Medical Publishers 1964."},{"issue":"Suppl.","key":"CR32","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1007\/BF02152377","volume":"4","author":"R. K. Schenk","year":"1970","unstructured":"Schenk, R. K., M\u00fcller, J., Zinkernagel, R., Willenegger, H.: Ultrastructure of normal and abnormal bone repair. Calcif. Tiss. Res. 4 (Suppl.), 110?111 (1970).","journal-title":"Calcif. Tiss. Res."},{"key":"CR33","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1007\/BF00442268","volume":"109","author":"A. Schuch","year":"1971","unstructured":"Schuch, A., Pesch, H.-J.: Beitrag zum Kleeblattsch\u00e4del-Syndrom. Z. Kinderheilk. 109, 187?198 (1971).","journal-title":"Z. Kinderheilk."},{"key":"CR34","doi-asserted-by":"crossref","first-page":"843","DOI":"10.1242\/jcs.6.3.843","volume":"6","author":"J. W. Smith","year":"1970","unstructured":"Smith, J. W.: The disposition of proteinpolysaccharide in the epiphyseal plate cartilage of the young rabbit. J. Cell Sci. 6, 843?864 (1970).","journal-title":"J. Cell Sci."},{"key":"CR35","first-page":"600","volume":"11","author":"V. Stanesco","year":"1966","unstructured":"Stanesco, V., Bona, C., Ionesco, V., Gottlieb, F.: Recherches histochimiques et histoenzymologiques sur le cartilage des croissance tibial de l'achondroplasie humaine. Rev. fran\u00e7. \u00c9tud. clin. biol. 11, 600?610 (1966).","journal-title":"Rev. fran\u00e7. \u00c9tud. clin. biol."},{"key":"CR36","doi-asserted-by":"crossref","first-page":"332","DOI":"10.1016\/S0022-5320(72)90009-3","volume":"38","author":"J. Thyberg","year":"1972","unstructured":"Thyberg, J.: Ultrastructural localization of aryl sulfatase activity in the epiphyseal plate. J. Ultrastruct. Res. 38, 332?342 (1972).","journal-title":"J. Ultrastruct. Res."},{"key":"CR37","doi-asserted-by":"crossref","first-page":"554","DOI":"10.1016\/S0022-5320(70)90181-4","volume":"33","author":"J. Thyberg","year":"1970","unstructured":"Thyberg, J., Friberg, U.: Ultrastructure and acid phosphatase activity of matrix vesicles and cytoplasmic dense bodies in the epiphyseal plate. J. Ultrastruct. Res. 33, 554?573 (1970).","journal-title":"J. Ultrastruct. Res."},{"key":"CR38","volume-title":"Bone and bones. Fundamentals of bone biology","author":"J. P. Weinmann","year":"1955","unstructured":"Weinmann, J. P., Sicher, H.: Bone and bones. Fundamentals of bone biology. London: Henry Kimpton 1955."},{"key":"CR39","first-page":"148","volume":"19","author":"D. G. Wollin","year":"1968","unstructured":"Wollin, D. G., Binnington, V. I., Partington, M. W.: Cloverleaf skull. J. Ass. Canad. Radiol. 19, 148?154 (1968).","journal-title":"J. Ass. Canad. Radiol."},{"key":"CR40","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/B978-1-4831-6751-0.50007-0","volume":"2","author":"G. C. Wood","year":"1964","unstructured":"Wood, G. C.: The precipitation of collagen fibers from solution. Intern. Rev. Connect. Tiss. Res. 2, 1?31 (1964).","journal-title":"Intern. Rev. Connect. Tiss. Res."}],"container-title":["Virchows Archiv Abteilung A Pathologische Anatomie"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF00542847.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/BF00542847\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF00542847","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,6,29]],"date-time":"2021-06-29T02:32:53Z","timestamp":1624933973000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/BF00542847"}},"subtitle":["Histological, histochemical and ultrastructural findings"],"short-title":[],"issued":{"date-parts":[[1972]]},"references-count":40,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1972]]}},"alternative-id":["BF00542847"],"URL":"https:\/\/doi.org\/10.1007\/bf00542847","relation":{},"ISSN":["0945-6317","1432-2307"],"issn-type":[{"value":"0945-6317","type":"print"},{"value":"1432-2307","type":"electronic"}],"subject":[],"published":{"date-parts":[[1972]]}}}