{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,20]],"date-time":"2026-02-20T23:07:13Z","timestamp":1771628833754,"version":"3.50.1"},"reference-count":47,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[1979,1,1]],"date-time":"1979-01-01T00:00:00Z","timestamp":283996800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pflugers Arch."],"published-print":{"date-parts":[[1979]]},"DOI":"10.1007\/bf00582324","type":"journal-article","created":{"date-parts":[[2004,11,23]],"date-time":"2004-11-23T00:14:32Z","timestamp":1101168872000},"page":"1-9","source":"Crossref","is-referenced-by-count":17,"title":["The role of the vagus nerves in the ventilatory response to loweredP a O2 with intact and eliminated carotid chemoreflexes"],"prefix":"10.1007","volume":"381","author":[{"given":"Heidrun","family":"Kiwull-Sch\ufffdne","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter","family":"Kiwull","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"CR1","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1113\/jphysiol.1974.sp010601","volume":"240","author":"A. Bartoli","year":"1974","unstructured":"Bartoli, A., Cross, B. A., Guz, A., Jain, S. K., Noble, M. I. M., Trenchard, D. W.: The effect of carbon dioxide in the airways and alveoli on ventilation; a vagal reflex studied in the dog. J. Physiol. (Lond.)240, 91?109 (1974)","journal-title":"J. Physiol. (Lond.)"},{"key":"CR2","first-page":"63","volume":"65","author":"J. Bouckaert","year":"1941","unstructured":"Bouckaert, J., Crimson, K. S., Heymans, C., Samaan, A.: Sur le m\ufffdcanisme de l'influence de l'hypox\ufffdmie sur la respiration et la circulation. Arch. Int. Pharmacodyn. Ther.65, 63?100 (1941)","journal-title":"Arch. Int. Pharmacodyn. Ther."},{"key":"CR3","doi-asserted-by":"crossref","first-page":"376","DOI":"10.1016\/0034-5687(70)90044-7","volume":"8","author":"P. Bouverot","year":"1970","unstructured":"Bouverot, P., Crance, J. P., Dejours, P.: Factors influencing the intensity of the Breuer-Hering inspiration-inhibiting reflex. Respir. Physiol.8, 376?384 (1970)","journal-title":"Respir. Physiol."},{"key":"CR4","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1016\/0034-5687(73)90062-5","volume":"17","author":"P. Bouverot","year":"1973","unstructured":"Bouverot, P., Candas, V., Libert, J. P.: Role of the arterial chemoreceptors in ventilatory adaptation to hypoxia of awake dogs and rabbits. Respir. Physiol.17, 209?219 (1973)","journal-title":"Respir. Physiol."},{"key":"CR5","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1113\/jphysiol.1976.sp011563","volume":"261","author":"G. W. Bradley","year":"1976","unstructured":"Bradley, G. W., Noble, M. I. M., Trenchard, D.: The direct effect on pulmonary stretch receptor discharge produced by changing lung carbon dioxide concentration in dogs on cardiopulmonary bypass and its action on breathing. J. Physiol. (Lond.)261, 359?373 (1976)","journal-title":"J. Physiol. (Lond.)"},{"key":"CR6","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1113\/jphysiol.1967.sp008148","volume":"188","author":"J. P. Chalmers","year":"1967","unstructured":"Chalmers, J. P., Korner, P. I., White, S. E.: The relative roles of the aortic and carotid sinus nerves in the rabbit in the control of respiration and circulation during arterial hypoxia and hypercapnia. J. Physiol. (Lond.)188, 435?450 (1967)","journal-title":"J. Physiol. (Lond.)"},{"key":"CR7","first-page":"88","volume":"77","author":"D. Colinet-Lagneaux","year":"1969","unstructured":"Colinet-Lagneaux, D., Troquet, J., Lambert, P.: Echanges gazeux et m\ufffdcanique respiratoire chez le lapin anesth\ufffdsi\ufffd. Influence de la vagotomie. Arch. Int. Physiol. Biochim.77, 88?104 (1969)","journal-title":"Arch. Int. Physiol. Biochim."},{"key":"CR8","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1152\/ajplegacy.1939.127.1.176","volume":"127","author":"J. H. Comroe Jr.","year":"1939","unstructured":"Comroe, J. H., Jr.: The location and function of the chemoreceptors of the aorta. Am. J. Physiol.127, 176?191 (1939)","journal-title":"Am. J. Physiol."},{"key":"CR9","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1113\/expphysiol.1957.sp001266","volume":"42","author":"R. S. Cormack","year":"1957","unstructured":"Cormack, R. S., Cunningham, D. J. C., Gee, J. B. L.: The effect of carbon dioxide on the respiratory response to want of oxygen in man. Q. J. Exp. Physiol.42, 303?319 (1957)","journal-title":"Q. J. Exp. Physiol."},{"key":"CR10","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/0034-5687(78)90050-6","volume":"34","author":"A. Davies","year":"1978","unstructured":"Davies, A., Dixon, M., Callanan, D., Huszczuk, A., Widdicombe, J. G., Wise, J. C. M.: Lung reflexes in rabbits during pulmonary stretch receptor block by sulphur dioxide. Respir. Physiol.34, 83?101 (1978)","journal-title":"Respir. Physiol."},{"key":"CR11","doi-asserted-by":"crossref","first-page":"558","DOI":"10.1152\/ajplegacy.1956.187.3.558","volume":"187","author":"H. L. Davis","year":"1956","unstructured":"Davis, H. L., Fowler, W. S., Lambert, E. H.: Effect of volume and rate of inflation and deflation on transpulmonary pressure and response of pulmonary stretch receptors. Am. J. Physiol.187, 558?566 (1956)","journal-title":"Am. J. Physiol."},{"key":"CR12","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1016\/0034-5687(76)90074-8","volume":"27","author":"H. Gautier","year":"1976","unstructured":"Gautier, H.: Pattern of breathing during hypoxia or hypercapnia of the awake or anesthetized cat. Respir. Physiol.27, 193?206 (1976)","journal-title":"Respir. Physiol."},{"issue":"Suppl. 35","key":"CR13","first-page":"1","volume":"11","author":"B. E. Gernandt","year":"1946","unstructured":"Gernandt, B. E.: A study of the respiratory reflexes elicited from the aortic and carotid bodies. Acta Physiol. Scand.11, Suppl. 35, 1?81 (1946)","journal-title":"Acta Physiol. Scand."},{"key":"CR14","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1007\/BF00585597","volume":"374","author":"K. Giese","year":"1978","unstructured":"Giese, K., Berndt, J., Berger, W.: Interaction of central and peripheral respiratory drives in cats. II. Peripheral and central interaction of hypoxia and hypercapnia. Pfl\ufffdgers Arch.374, 211?217 (1978)","journal-title":"Pfl\ufffdgers Arch."},{"key":"CR15","first-page":"19","volume":"181","author":"M. Green","year":"1965","unstructured":"Green, M.: The effects of changes in gas viscosity on measurement of gas flow rates and volumes by the pneumotachograph. J. Physiol. (Lond.)181, 19?20P (1965)","journal-title":"J. Physiol. (Lond.)"},{"key":"CR16","doi-asserted-by":"crossref","first-page":"420","DOI":"10.1113\/jphysiol.1919.sp001841","volume":"52","author":"J. S. Haldane","year":"1919","unstructured":"Haldane, J. S., Meakins, J. C., Priestley, J. G.: The respiratory response to anoxaemia. J. Physiol. (Lond.)52, 420?432 (1919)","journal-title":"J. Physiol. (Lond.)"},{"key":"CR17","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1016\/0034-5687(68)90066-2","volume":"5","author":"Y. Honda","year":"1968","unstructured":"Honda, Y.: Ventilatory response to CO2 during hypoxia and hyperoxia in awake and anesthetized rabbits. Respir. Physiol.5, 279?287 (1968)","journal-title":"Respir. Physiol."},{"key":"CR18","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1152\/jappl.1966.21.2.423","volume":"21","author":"Y. Honda","year":"1966","unstructured":"Honda, Y., Kreuzer, F.: PO2-ventilation response curve with normal pH and PCO2 in the dog. J. Appl. Physiol.21 423?433 (1966)","journal-title":"J. Appl. Physiol."},{"key":"CR19","doi-asserted-by":"crossref","unstructured":"Kao, F. F., Mei, S. S.: The central multiplicative interaction of PO2 and PCO2 on ventilation. In: The regulation of respiration during sleep and anesthesia (R. S. Fitzgerald, H. Gautier and S. Lahiri, eds.). Adv. Exp. Med. Biol.99, 403?414 (1978)","DOI":"10.1007\/978-1-4613-4009-6_43"},{"key":"CR20","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1113\/jphysiol.1969.sp008754","volume":"201","author":"W. Karczewski","year":"1969","unstructured":"Karczewski, W., Widdicombe, J. G.: The effect of vagotomy vagal cooling and efferent vagal stimulation on breathing and lung mechanics of rabbits. J. Physiol. (Lond.)201, 259?270 (1969)","journal-title":"J. Physiol. (Lond.)"},{"key":"CR21","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1113\/expphysiol.1975.sp002322","volume":"60","author":"M. Kashani","year":"1975","unstructured":"Kashani, M., Haigh, A. L.: The effects of vagotomy on ventilation and blood gas composition in dog, sheep and rabbit. Q. J. Exp. Physiol.60, 285?298 (1975)","journal-title":"Q. J. Exp. Physiol."},{"key":"CR22","first-page":"226","volume":"12","author":"P. Kiwull","year":"1976","unstructured":"Kiwull, P., Kiwull-Sch\ufffdne, H.: The role of vagal afferents in the interaction of chemical respiratory drives. Bull. Physiopathol. Resp.12, 226?227P (1976)","journal-title":"Bull. Physiopathol. Resp."},{"key":"CR23","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1007\/BF00588731","volume":"330","author":"P. Kiwull","year":"1971","unstructured":"Kiwull, P., Wiemer, W.: Der Einflu\ufffd der Vagusausschaltung auf die Wirkung der elektrischen Sinusnervenreizung. Pfl\ufffdgers Arch.330, 15?27 (1971)","journal-title":"Pfl\ufffdgers Arch."},{"key":"CR24","first-page":"137","volume-title":"Central rhythmic and regulation","author":"P. Kiwull","year":"1974","unstructured":"Kiwull, P., Sch\ufffdne, H., Wiemer, W., Klatt, H.: Quantitation of interaction of respiratory drives. In: Central rhythmic and regulation (W. Umbach and H. P. Koepchen, eds.), pp. 137?146. Stuttgart: Hippokrates 1974"},{"key":"CR25","first-page":"146","volume-title":"Acid base homeostasis of the brain extracellular fluid and the respiratory control system","author":"P. Kiwull","year":"1976","unstructured":"Kiwull, P., Kiwull-Sch\ufffdne, H., Klatt, H.: Interaction of central and peripheral respiratory drives: Differentiation between the role of stimuli and afferents. In: Acid base homeostasis of the brain extracellular fluid and the respiratory control system (H. H. Loeschcke, ed.), pp. 146?156. Stuttgart: Thieme 1976"},{"key":"CR26","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1007\/978-3-642-66755-8_27","volume-title":"Chemoreception in the carotid body","author":"H. Kiwull-Sch\ufffdne","year":"1977","unstructured":"Kiwull-Sch\ufffdne, H., Kiwull, P.: Multifactor influences on the functional relationship between ventilation and arterial oxygen pressure. In: Chemoreception in the carotid body (H. Acker, C. Eyzaguirre, S. J. Fidone, D. W. L\ufffdbbers, D. J. Pallot, and R. W. Torrance, eds.), pp. 190?197. Berlin, Heidelberg, New York: Springer 1977"},{"key":"CR27","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/0034-5687(72)90092-8","volume":"16","author":"R. Kronenberg","year":"1972","unstructured":"Kronenberg, R., Hamilton, F. N., Gabel, R., Hickey, R., Read, D. J. C., Severinghaus, J.: Comparison of three methods for quantitating respiratory response to hypoxia in man. Respir. Physiol.16, 109?125 (1972)","journal-title":"Respir. Physiol."},{"key":"CR28","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1016\/0034-5687(75)90018-3","volume":"24","author":"S. Lahiri","year":"1975","unstructured":"Lahiri, S., DeLaney, R. G.: Relationship between carotid chemoreceptor activity and ventilation in the cat. Respir. Physiol.24, 267?286 (1975)","journal-title":"Respir. Physiol."},{"key":"CR29","doi-asserted-by":"crossref","first-page":"460","DOI":"10.1007\/BF00361733","volume":"267","author":"H. H. Loeschcke","year":"1958","unstructured":"Loeschcke, H. H., Gertz, K. H.: Einflu\ufffd des O2-Druckes in der Einatmungsluft auf die Atemt\ufffdtigkeit des Menschen, gepr\ufffdft unter Konstanthaltung des alveolaren CO2-Druckes. Pfl\ufffdgers Arch.267, 460?477 (1958)","journal-title":"Pfl\ufffdgers Arch."},{"key":"CR30","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/0034-5687(75)90069-9","volume":"23","author":"M. J. Miller","year":"1975","unstructured":"Miller, M. J., Tenney, S. M.: Hypoxia-induced tachypnea in carotid deafferented cats. Respir. Physiol.23, 31?39 (1975)","journal-title":"Respir. Physiol."},{"key":"CR31","doi-asserted-by":"crossref","first-page":"826","DOI":"10.1152\/jappl.1970.28.6.826","volume":"28","author":"A. H. Mines","year":"1970","unstructured":"Mines, A. H., S\ufffdrensen, S. C.: Ventilatory responses of awake normal goats during acute and chronic hypoxia. J. Appl. Physiol.28, 826?831 (1970)","journal-title":"J. Appl. Physiol."},{"key":"CR32","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/0034-5687(72)90051-5","volume":"16","author":"M. E. K. Y. Mustafa","year":"1972","unstructured":"Mustafa, M. E. K. Y., Purves, M. J.: The effect of CO2 upon discharge from slowly adapting stretch receptors in the lungs of rabbits. Respir. Physiol.16, 197?212 (1972)","journal-title":"Respir. Physiol."},{"key":"CR33","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1111\/j.1748-1716.1952.tb00847.x","volume":"24","author":"M. Nielsen","year":"1952","unstructured":"Nielsen, M., Smith, H.: Studies on the regulation of respiration in acute hypoxia. Acta Physiol. Scand.24, 293?313 (1952)","journal-title":"Acta Physiol. Scand."},{"key":"CR34","first-page":"648","volume":"60","author":"N. Ott","year":"1971","unstructured":"Ott, N., Kiwull, P., Wiemer, W.: Zur Bedeutung der Chemoreflexe des Karotis- und Aortengebietes f\ufffdr die Atmungs- und Blutdruckregulation bei herabgesetztem Blutdruck. Z. Kreisl.-Forsch.60, 648?660 (1971)","journal-title":"Z. Kreisl.-Forsch."},{"key":"CR35","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1016\/0034-5687(76)90029-3","volume":"28","author":"L. C. Ou","year":"1976","unstructured":"Ou, L. C., Miller, M. J., Tenney, S. M.: Hypoxia and carbon dioxide as separate and interactive depressants of ventilation. Respir. Physiol.28, 347?358 (1976)","journal-title":"Respir. Physiol."},{"key":"CR36","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1152\/physrev.1973.53.1.159","volume":"53","author":"A. S. Paintal","year":"1973","unstructured":"Paintal, A. S.: Vagal sensory receptors and their reflex effects. Physiol. Rev.53, 159?227 (1973)","journal-title":"Physiol. Rev."},{"key":"CR37","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1152\/jappl.1970.29.4.475","volume":"29","author":"E. A. Phillipson","year":"1970","unstructured":"Phillipson, E. A., Hickey, R. F., Bainton, C. R., Nadel, J. A.: Effects of vagal blockade on regulation of breathing in conscious dogs. J. Appl. Physiol.29, 475?479 (1970)","journal-title":"J. Appl. Physiol."},{"key":"CR38","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1007\/BF00412791","volume":"291","author":"K. Pleschka","year":"1966","unstructured":"Pleschka, K., Albers, C., Usinger, W.: Die Bedeutung des Vagus f\ufffdr die CO2-Schwelle der Atmung unter besonderer Ber\ufffdcksichtigung des Hirnvenenblutes. Pfl\ufffdgers Arch.291, 205?220 (1966)","journal-title":"Pfl\ufffdgers Arch."},{"key":"CR39","first-page":"519","volume":"73","author":"J. G. Ramos","year":"1956","unstructured":"Ramos, J. G.: The reflex responses to inflation or deflation of the lungs and their importance in the regulation of respiration. Am. Rev. Tuberc.73, 519?528 (1956)","journal-title":"Am. Rev. Tuberc."},{"key":"CR40","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1113\/jphysiol.1976.sp011404","volume":"258","author":"A. S. Rebuck","year":"1976","unstructured":"Rebuck, A. S., Rigg, J. R. A., Saunders, N. A.: Respiratory frequency response to progressive isocapnic hypoxia. J. Physiol. (Lond.)258, 19?31 (1976)","journal-title":"J. Physiol. (Lond.)"},{"key":"CR41","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1016\/0034-5687(69)90073-5","volume":"7","author":"P. S. Richardson","year":"1969","unstructured":"Richardson, P. S., Widdicombe, J. G.: The role of the vagus nerve in the ventilatory responses to hypercapnia and hypoxia in anesthetized and unanesthetized rabbits. Respir. Physiol.7, 122?135 (1969)","journal-title":"Respir. Physiol."},{"key":"CR42","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1113\/jphysiol.1908.sp001272","volume":"37","author":"F. H. Scott","year":"1908","unstructured":"Scott, F. H.: On the relative parts played by nervous and chemical factors in the regulation of respiration. J. Physiol. (Lond.)37, 301?326 (1908)","journal-title":"J. Physiol. (Lond.)"},{"key":"CR43","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/0034-5687(75)90066-3","volume":"23","author":"W. M. St. John","year":"1975","unstructured":"St. John, W. M.: Differing responses to hypercapnia and hypoxia following pneumotaxic center ablation. Respir. Physiol.23, 1?9 (1975)","journal-title":"Respir. Physiol."},{"key":"CR44","first-page":"163","volume":"21","author":"J. G. Widdicombe","year":"1961","unstructured":"Widdicombe, J. G.: Respiratory reflexes in man and other mammalian species. Clin. Sci.21, 163?170 (1961)","journal-title":"Clin. Sci."},{"key":"CR45","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1007\/BF00588732","volume":"330","author":"W. Wiemer","year":"1971","unstructured":"Wiemer, W., Kiwull, P.: Der Einflu\ufffd desP A CO2 auf die Wirkung der Sinusnervenreizung bei intakten und ausgeschalteten Nn. vagi. Pfl\ufffdgers Arch.330, 28?44 (1971)","journal-title":"Pfl\ufffdgers Arch."},{"key":"CR46","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1007\/BF00592929","volume":"336","author":"W. Wiemer","year":"1972","unstructured":"Wiemer, W., Kiwull, P.: The role of the vagus nerves in the respiratory response to CO2 under hyperoxic conditions. Pfl\ufffdgers Arch.336, 147?170 (1972)","journal-title":"Pfl\ufffdgers Arch."},{"key":"CR47","first-page":"58","volume":"112","author":"H. Winterstein","year":"1960","unstructured":"Winterstein, H., Fr\ufffdmter, E.: Der zentrale Angriffspunkt der Vagushemmung. Z. Biol.112, 58?66 (1960)","journal-title":"Z. Biol."}],"container-title":["Pfl\ufffdgers Archiv European Journal of Physiology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF00582324.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/BF00582324\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF00582324","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,4,4]],"date-time":"2020-04-04T07:14:10Z","timestamp":1585984450000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/BF00582324"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1979]]},"references-count":47,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1979]]}},"alternative-id":["BF00582324"],"URL":"https:\/\/doi.org\/10.1007\/bf00582324","relation":{},"ISSN":["0031-6768","1432-2013"],"issn-type":[{"value":"0031-6768","type":"print"},{"value":"1432-2013","type":"electronic"}],"subject":[],"published":{"date-parts":[[1979]]}}}