{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,4]],"date-time":"2026-07-04T01:46:16Z","timestamp":1783129576838,"version":"3.54.6"},"reference-count":22,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[1975,1,1]],"date-time":"1975-01-01T00:00:00Z","timestamp":157766400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Eur J Clin Pharmacol"],"published-print":{"date-parts":[[1975]]},"DOI":"10.1007\/bf00613427","type":"journal-article","created":{"date-parts":[[2004,11,25]],"date-time":"2004-11-25T16:59:10Z","timestamp":1101401950000},"page":"39-47","source":"Crossref","is-referenced-by-count":26,"title":["Absorption of digoxin in man after oral and intrasigmoid administration studied by portal vein catheterization"],"prefix":"10.1007","volume":"9","author":[{"given":"K. -E.","family":"Andersson","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.","family":"Nyberg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H.","family":"Dencker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"G\ufffdthlin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"CR1","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1042\/cs0430507","volume":"43","author":"B. Beermann","year":"1972","unstructured":"Beermann, B., Hellstr\u00f6m, K., Ros\u00e9n, A.: The absorption of orally administered 12 ?-3H digoxin in man. Clin. Sci.43, 507?518 (1972a).","journal-title":"Clin. Sci."},{"key":"CR2","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1007\/BF00560890","volume":"5","author":"B. Beermann","year":"1972","unstructured":"Beermann, B., Hellstr\u00f6m, K., Ros\u00e9n, A., Werner, B.: Elimination of orally administered digoxin and digitoxin by thoracic duct drainage in man. Europ. J. clin. Pharmacol.5, 19?21 (1972b)","journal-title":"Europ. J. clin. Pharmacol."},{"key":"CR3","first-page":"290","volume-title":"Textbook of physiology and biochemistry","author":"G.H. Bell","year":"1965","unstructured":"Bell, G.H., Davidson, J.N., Scarborough, H.: Textbook of physiology and biochemistry, 6th ed., Edinburgh and London: E. and S. Living-stone, Chapter 18, p. 290, 1965"},{"key":"CR4","doi-asserted-by":"crossref","first-page":"708","DOI":"10.1016\/S0140-6736(72)92112-5","volume":"II","author":"A. Bertler","year":"1972","unstructured":"Bertler, A., Medin, S., Nyberg, L., Redfors, A.: Bioavailability of digoxin. Lancet1972 II, 708","journal-title":"Lancet"},{"key":"CR5","first-page":"2163","volume":"100","author":"R. Blankart","year":"1970","unstructured":"Blankart, R., Preisig, R.: Pharmakokinetische Grundlagen der Digitalisdosierung: eine Studie an Probanden. Schweiz. med. Wschr.100, 2163?2164 (1970)","journal-title":"Schweiz. med. Wschr."},{"key":"CR6","doi-asserted-by":"crossref","first-page":"1747","DOI":"10.1152\/ajplegacy.1969.217.6.1747","volume":"217","author":"J.H. Caldwell","year":"1969","unstructured":"Caldwell, J.H., Martin, J.F., Dutta, S., Greenberger, N.J.: Intestinal absorption of digoxin-3H in the rat. Amer. J. Physiol.217, 1747?1751 (1969)","journal-title":"Amer. J. Physiol."},{"key":"CR7","first-page":"64","volume":"23","author":"H.J. Dengler","year":"1973","unstructured":"Dengler, H.J., Dodem, G., Wirth, K.: Pharmakokinetische Untersuchungen mit H3-Digoxin und H3-Lanatosid beim Menschen. Arzneimittel-Forsch.23, 64?74 (1973)","journal-title":"Arzneimittel-Forsch."},{"key":"CR8","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1097\/00000441-196806000-00006","volume":"255","author":"J.E. Doherty","year":"1968","unstructured":"Doherty, J.E.: The clinical pharmacology of digitalis glycosides: A review. Amer. J. med. Sci.255, 382?414 (1968)","journal-title":"Amer. J. med. Sci."},{"key":"CR9","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1001\/archinte.1961.03620100023004","volume":"108","author":"J.E. Doherty","year":"1961","unstructured":"Doherty, J.E., Perkins, W.H., Mitchell, G.K.: Tritiated digoxin studies in human subjects. Arch. intern. Med.108, 531?539 (1961)","journal-title":"Arch. intern. Med."},{"key":"CR10","first-page":"272","volume":"84","author":"R.B. Fisher","year":"1950","unstructured":"Fisher, R.B., Parsons, D.S.: The gradient of mucosal surface in the small intestine of the rat. J. Anat. (Lond.)84, 272?282 (1950)","journal-title":"J. Anat."},{"key":"CR11","doi-asserted-by":"crossref","first-page":"406","DOI":"10.1007\/BF01002379","volume":"264","author":"W. Forth","year":"1969","unstructured":"Forth, W., Furukawa, E., Rummel, W., Andres, H.: Die Bestimmung der intestinalen Resorption von Herzglykosiden durch Messung der3H-markierten Glykoside im Portalvenenblut und in der Darmlymphe bei Katzen. Naunyn-Schmiedebergs Arch. Pharmak.264, 406?419 (1969)","journal-title":"Naunyn-Schmiedebergs Arch. Pharmak."},{"key":"CR12","first-page":"45","volume":"109","author":"H. Gold","year":"1953","unstructured":"Gold, H., Cattell, Mc K, Greiner, T., Hanlon, L.W., Kwit, N.T., Modell, W., Cotlove, E., Benton, J., Otto, H.L.: Clinical pharmacology of digoxin. J. Pharmacol. exp. Ther.109, 45?57 (1953)","journal-title":"J. Pharmacol. exp. Ther."},{"key":"CR13","first-page":"265","volume":"167","author":"N.J. Greenberger","year":"1969","unstructured":"Greenberger, N.J., Mac Dermott, R.P., Martin, J.F., Dutta, S.: Intestinal absorption of six tritium-labeled digitalis glycosides in rats and guinea pigs. J. Pharmacol. exp. Ther.167, 265?273 (1969)","journal-title":"J. Pharmacol. exp. Ther."},{"key":"CR14","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1016\/0014-2999(72)90103-3","volume":"19","author":"A. Haass","year":"1972","unstructured":"Haass, A., L\u00fcllman, H., Peters, T.: Absorption rates of some cardiac glycosides and portal blood flow. Europ. J. Pharmacol.19, 366?370 (1972)","journal-title":"Europ. J. Pharmacol."},{"key":"CR15","doi-asserted-by":"crossref","first-page":"903","DOI":"10.1007\/BF02238171","volume":"16","author":"W.H. Hall","year":"1971","unstructured":"Hall, W.H., Doherty, J.E.: Tritiated digoxin. XVI. Gastric absorption. Amer. J. Dig. Dis.16, 903?908 (1971)","journal-title":"Amer. J. Dig. Dis."},{"key":"CR16","first-page":"447","volume":"11","author":"L. Nyberg","year":"1974","unstructured":"Nyberg, L., Bratt, L., Forsgren, A., Hugosson, S.: Bioavailability of digoxin from tablets. I.In vitro characterization of digoxin tablets. Acta pharm. suecia11, 447?458 (1974a)","journal-title":"Acta pharm. suecia"},{"key":"CR17","first-page":"459","volume":"11","author":"L. Nyberg","year":"1974","unstructured":"Nyberg, L., Andersson, K.-E., Bertler, A.: Bioavailability of digoxin from tablets. II. Radioimmunoassay and disposition pharmacokinetics of digoxin after intravenous administration. Acta pharm. suecica11, 459?470 (1974b)","journal-title":"Acta pharm. suecica"},{"key":"CR18","first-page":"471","volume":"11","author":"L. Nyberg","year":"1974","unstructured":"Nyberg, L., Andersson, K.-E., Bertler, A.: Bioavailability of digoxin from tablets. III. Availability of digoxin in man from preparations with different dissolution rate. Acta pharm. suecica11, 471?492 (1974c)","journal-title":"Acta pharm. suecica"},{"key":"CR19","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1161\/01.RES.29.4.419","volume":"29","author":"G.C. Oliver","year":"1971","unstructured":"Oliver, G.C., Cooksey, J., Witte, C., Witte, M.: Absorption and transport of digitoxin in the dog. Circulat. Res.29, 419?423 (1971)","journal-title":"Circulat. Res."},{"key":"CR20","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1007\/BF00501851","volume":"274","author":"N. Rietbrock","year":"1972","unstructured":"Rietbrock, N., Abshagen, U., von Bergmann, K., Kewitz, H.: Pharmacokinetics of digoxin and its 4?-acetyl- and methylderivatives in the rat. Naunyn-Schmiedeberg's Arch. Pharmacol.274, 171?181 (1972)","journal-title":"Naunyn-Schmiedeberg's Arch. Pharmacol."},{"key":"CR21","first-page":"635","volume":"136","author":"E. Steiness","year":"1974","unstructured":"Steiness, E., Rasmussen, F., Svendsen, O., Johansen, H.: Administrationsformer for digoksin. Ugeskr. Laeg.136, 635?638 (1974)","journal-title":"Ugeskr. Laeg."},{"key":"CR22","doi-asserted-by":"crossref","first-page":"768","DOI":"10.1016\/0002-9149(66)90370-5","volume":"17","author":"A.M. Weissler","year":"1966","unstructured":"Weissler, A.M., Snyder, J.R., Schoenfield, C.D., Cohen, S.: Assay of digitalis glycosides in man. Amer. J. Cardiol..17, 768?778 (1966)","journal-title":"Amer. J. Cardiol."}],"container-title":["European Journal of Clinical Pharmacology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF00613427.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/BF00613427\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF00613427","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,4,4]],"date-time":"2020-04-04T08:51:34Z","timestamp":1585990294000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/BF00613427"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1975]]},"references-count":22,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1975]]}},"alternative-id":["BF00613427"],"URL":"https:\/\/doi.org\/10.1007\/bf00613427","relation":{},"ISSN":["0031-6970","1432-1041"],"issn-type":[{"value":"0031-6970","type":"print"},{"value":"1432-1041","type":"electronic"}],"subject":[],"published":{"date-parts":[[1975]]}}}