{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,5]],"date-time":"2026-06-05T19:43:31Z","timestamp":1780688611029,"version":"3.54.1"},"reference-count":12,"publisher":"Springer Science and Business Media LLC","issue":"2-3","license":[{"start":{"date-parts":[[1975,1,1]],"date-time":"1975-01-01T00:00:00Z","timestamp":157766400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Eur J Clin Pharmacol"],"published-print":{"date-parts":[[1975]]},"DOI":"10.1007\/bf00614002","type":"journal-article","created":{"date-parts":[[2004,11,25]],"date-time":"2004-11-25T04:44:04Z","timestamp":1101357844000},"page":"91-93","source":"Crossref","is-referenced-by-count":13,"title":["Combination therapy of essential hypertension with pindolol (Visken) and hydralazine"],"prefix":"10.1007","volume":"9","author":[{"given":"I.","family":"Persson","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"CR1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1097\/00005792-196701000-00001","volume":"46","author":"D. Alarcon-Segovia","year":"1967","unstructured":"Alarcon-Segovia, D., Wakum, K., Worthington, J., Emmerson, J.: Clincal and experimental studies on the hydralazine syndrome and its relationship to systemic lupus erythematosus. Medicine (Baltimore)46, 1?33 (1967)","journal-title":"Medicine"},{"key":"CR2","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1161\/01.CIR.8.2.199","volume":"8","author":"E.D. Freis","year":"1953","unstructured":"Freis, E.D., Rose, J.C., Higgins, T.F.: The hemodynamic effects of hypotensive drugs in man. IV. 1-Hydrazinophthalazine. Circulation8, 199?204 (1953)","journal-title":"Circulation"},{"key":"CR3","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1152\/physrev.1960.40.1.27","volume":"40","author":"E. Freis","year":"1960","unstructured":"Freis, E.: Hemodynamics of hypertension. Physiol. Rev.40, 27?54 (1960)","journal-title":"Physiol. Rev."},{"key":"CR4","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1056\/NEJM197003052821001","volume":"282","author":"E. Gilmore","year":"1970","unstructured":"Gilmore, E., Weil, J., Chidsey, C.: Treatment of essential hypertension with a new vasodilator in combination with beta-adrenergic blockade. New Engl. J. Med.282, 521?527 (1970)","journal-title":"New Engl. J. Med."},{"key":"CR5","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1161\/01.CIR.45.3.571","volume":"45","author":"T. Gottlieb","year":"1972","unstructured":"Gottlieb, T., Katz, F., Chidsey, C.: Combined therapy with vasodilator drugs and beta-adrenergic blockade in hypertension. Circulation45, 571?582 (1972)","journal-title":"Circulation"},{"key":"CR6","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1111\/j.0954-6820.1971.tb07470.x","volume":"190","author":"L. Hansson","year":"1971","unstructured":"Hansson, L., Orlander, R., Aberg, H., Malmcrona, R., Westerlund, A.: Treatment of hypertension with propranolol and hydralazine. Acta med. scand.190, 531?534 (1971)","journal-title":"Acta med. scand."},{"key":"CR7","first-page":"728","volume-title":"The pharmacological basis of therapeutics","author":"M. Nickerson","year":"1970","unstructured":"Nickerson, M.: Antihypertensive agents and the drug therapy of hypertension. In: The pharmacological basis of therapeutics. Fourth edition. (eds. L. Goodman, L. Gilman), p. 728. New York: The Macmillan Company 1970","edition":"Fourth edition"},{"key":"CR8","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1007\/BF00644734","volume":"6","author":"I. Persson","year":"1973","unstructured":"Persson, I., Ulrich, J.: Treatment of hypertension with a new beta-blocking agent, pindolol (Visk\u00e9n). Europ. J. clin. Pharmacol.6, 217?219 (1973)","journal-title":"Europ. J. clin. Pharmacol."},{"key":"CR9","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1136\/bmj.1.5635.7","volume":"I","author":"B. Prichard","year":"1969","unstructured":"Prichard, B., Gillam, P.: Treatment of hypertension with propranolol. Brit. med. J.1969 I, 7?16","journal-title":"Brit. med. J."},{"key":"CR10","doi-asserted-by":"crossref","first-page":"718","DOI":"10.1016\/0002-9149(72)90176-2","volume":"29","author":"R. Sannerstedt","year":"1972","unstructured":"Sannerstedt, R., Stenberg, J., Vedin, A.: Chronic beta adrenergic blockade in hypertension. Amer. J. Cardiol.29, 718?723 (1972)","journal-title":"Amer. J. Cardiol."},{"key":"CR11","doi-asserted-by":"crossref","first-page":"1217","DOI":"10.1016\/S0140-6736(67)90561-2","volume":"II","author":"E. Shinebourne","year":"1967","unstructured":"Shinebourne, E., Fleming, J., Hamer, J.: Effects of beta-adrenergic blockade during exercise in hypertensive and ischaemic heart-disease. Lancet1967 II, 1217?1220","journal-title":"Lancet"},{"key":"CR12","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1136\/bmj.2.5912.193","volume":"II","author":"D. Warren","year":"1974","unstructured":"Warren, D., Swainson, E., Wright, N.: Deterioration in renal function after beta-blockade in patients with chronic renal failure and hypertension. Brit. med. J.1974 II, 193?194","journal-title":"Brit. med. J."}],"container-title":["European Journal of Clinical Pharmacology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF00614002.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/BF00614002\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF00614002","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,4,5]],"date-time":"2019-04-05T03:42:53Z","timestamp":1554435773000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/BF00614002"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1975]]},"references-count":12,"journal-issue":{"issue":"2-3","published-print":{"date-parts":[[1975]]}},"alternative-id":["BF00614002"],"URL":"https:\/\/doi.org\/10.1007\/bf00614002","relation":{},"ISSN":["0031-6970","1432-1041"],"issn-type":[{"value":"0031-6970","type":"print"},{"value":"1432-1041","type":"electronic"}],"subject":[],"published":{"date-parts":[[1975]]}}}