{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T08:44:52Z","timestamp":1791017092413,"version":"4.1.0"},"reference-count":23,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[1993,1,1]],"date-time":"1993-01-01T00:00:00Z","timestamp":725846400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Breast Cancer Res Tr"],"published-print":{"date-parts":[[1993,1]]},"DOI":"10.1007\/bf00666586","type":"journal-article","created":{"date-parts":[[2004,11,27]],"date-time":"2004-11-27T13:41:01Z","timestamp":1101562861000},"page":"251-260","source":"Crossref","is-referenced-by-count":30,"title":["Establishment and characterization of a new cell line from primary human breast carcinoma"],"prefix":"10.1007","volume":"28","author":[{"given":"Dino","family":"Amadori","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Livia","family":"Bertoni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alberto","family":"Flamigni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saverio","family":"Savini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carla","family":"De Giovanni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Silvia","family":"Casanova","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Franca","family":"De Paola","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Amadori","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elena","family":"Giulotto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wainer","family":"Zoli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"CR1","first-page":"103","volume":"738","author":"HE Smith","year":"1984","unstructured":"Smith HE, Wolman S, Hackett AJ: The biology of breast cancer at the cellular level. Biochem Biophys Acta 738:103?123, 1984","journal-title":"Biochem Biophys Acta"},{"key":"CR2","first-page":"4327","volume":"38","author":"WL Engel","year":"1978","unstructured":"Engel WL, Young NA: Human breast carcinoma cells in continuous culture: a review. Cancer Res 38: 4327?4339, 1978","journal-title":"Cancer Res"},{"key":"CR3","doi-asserted-by":"crossref","first-page":"1795","DOI":"10.1093\/jnci\/58.6.1795","volume":"58","author":"AJ Hackett","year":"1977","unstructured":"Hackett AJ, Smith HS, Springer EL, Owens RB, Nelson-Rees WA, Riggs JL, Gardner MB: Two syngeneic cell lines from human breast tissue: the aneuploid mammary epithelial (Hs578T) and the diploid myoepithelial (Hs578Bst) cell lines. J Nat Cancer Inst 58: 1795?1806, 1977","journal-title":"J Nat Cancer Inst"},{"key":"CR4","first-page":"3100","volume":"35","author":"RE Norquist","year":"1975","unstructured":"Norquist RE, Ishmael DR, Lovig CA, Hyder DM, Hoge AF: The tissue culture and morphology of human breast tumor cell line BOT-2. Cancer Res 35: 3100?3105, 1975","journal-title":"Cancer Res"},{"key":"CR5","first-page":"967","volume":"61","author":"EY Lasfargues","year":"1975","unstructured":"Lasfargues EY, Coutinho WG, Redfield ES: Isolation of two human tumor epithelial cell lines from solid breast carcinomas. J Nat Cancer Inst 61: 967?976, 1975","journal-title":"J Nat Cancer Inst"},{"key":"CR6","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1038\/bjc.1989.248","volume":"60","author":"S Minafra","year":"1989","unstructured":"Minafra S, Morello V, Glorioso F, La Fiura AM, Tommasino RM, Feo S, McIntosh D, Wolley DE: A new cell line (8701-BC) from primary ductal infiltrating carcinoma of human breast. Br J Cancer 60: 185?192, 1989","journal-title":"Br J Cancer"},{"key":"CR7","doi-asserted-by":"crossref","first-page":"727","DOI":"10.1038\/bjc.1991.164","volume":"63","author":"P Meltzer","year":"1991","unstructured":"Meltzer P, Leibovitz A, Dalton W, Villar H, Kute T, Davis J, Nagle R, Trent J: Establishment of two new cell lines derived from human breast carcinoma with Her-2\/Neu amplification. Br J Cancer 63: 727?735, 1991","journal-title":"Br J Cancer"},{"key":"CR8","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1007\/BF01806372","volume":"17","author":"W Zoli","year":"1990","unstructured":"Zoli W, Volpi A, Bonaguri C, Riccobon A, Savini S, Brizio S, Saragoni A, Medri L, Marra GA, Amadori D: An efficient method for culturing human breast carcinoma to evaluate drug activityin vitro: experience on 136 primary cancers and on 116 recurrences. Breast Cancer Res Treat 17: 231?238, 1990","journal-title":"Breast Cancer Res Treat"},{"key":"CR9","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1177\/030089168907500413","volume":"75","author":"R Silvestrini","year":"1989","unstructured":"Silvestrini R, Daidone MG, Costa A: Cell kinetics of solid tumors with time and its clinical implication. Tumori 75: 367?372, 1989","journal-title":"Tumori"},{"key":"CR10","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1007\/BF01975439","volume":"18","author":"D Amadori","year":"1991","unstructured":"Amadori D, Bonaguri C, Nanni O, Gentilini P, Lundi N, Zoli W, Riccobon A, Vio A, Magni E, Saragoni A: Cell kinetics and hormonal features in relation to pathological stage in breast cancer. Breast Cancer Res Treat 18: 19?25, 1991","journal-title":"Breast Cancer Res Treat"},{"key":"CR11","doi-asserted-by":"crossref","first-page":"414","DOI":"10.1007\/BF02618365","volume":"16","author":"MR Stampfer","year":"1980","unstructured":"Stampfer MR, Hallowes RC, Hackett AJ: Growth of normal human mammary cells in culture. In Vitro 16: 414?425, 1980","journal-title":"In Vitro"},{"key":"CR12","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1177\/030089168807400406","volume":"74","author":"R Agresti","year":"1988","unstructured":"Agresti R, Alzani R, Andreola S, Bedini V, Gianni S, Menard S, Rilke F, Colnaghi MI: Histopathological characterization of a novel monoclonal antibody, MLuC1, reacting with lung carcinomas. Tumori 74: 401?410, 1988","journal-title":"Tumori"},{"key":"CR13","first-page":"1295","volume":"43","author":"S Menard","year":"1983","unstructured":"Menard S, Tagliabue E, Canevari S, Fossati G, Colnaghi MI: Generation of monoclonal antibodies reacting with normal and cancer cells of human breast. Cancer Res 43: 1295?1300, 1983","journal-title":"Cancer Res"},{"key":"CR14","volume-title":"Correlation between the expression of breast carcinoma markers defined by monoclonal antibodies and tumor progression (Abstract)","author":"G Porro","year":"1987","unstructured":"Porro G, Agresti R, da Dalt MG, Menard S, Colnaghi MI: Correlation between the expression of breast carcinoma markers defined by monoclonal antibodies and tumor progression (Abstract). Biennial International Breast Cancer Research Conference, Miami, 1987"},{"key":"CR15","first-page":"111","volume":"39","author":"HH Mollenhauer","year":"1964","unstructured":"Mollenhauer HH: PLastic embedding mixture for use in electron microscopy. Stain Technol 39: 111?114, 1964","journal-title":"Stain Technol"},{"key":"CR16","doi-asserted-by":"crossref","first-page":"2115","DOI":"10.1002\/j.1460-2075.1986.tb04474.x","volume":"5","author":"E Giulotto","year":"1986","unstructured":"Giulotto E, Saito I, Stark GR: Structure of DNA formed in the first step of cad gene amplification. EMBO J 5: 2115?2121, 1986","journal-title":"EMBO J"},{"key":"CR17","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1038\/319230a0","volume":"319","author":"T Yamamoto","year":"1986","unstructured":"Yamamoto T, Ikawa S, Akiyama T, Semba K, Nomura N, Miyasima N, Saito K, Toyoshima K: Similarity of protein encoded by the human c-erbB-2 gene to epidermal growth factor-receptor. Nature 319: 230?234, 1986","journal-title":"Nature"},{"key":"CR18","doi-asserted-by":"crossref","first-page":"817","DOI":"10.1038\/316817a0","volume":"316","author":"JR Riordan","year":"1985","unstructured":"Riordan JR, Deuchars K, Kartner N, Alon N, Trent J, Living V: Amplification of P-glycoprotein genes in multidrug-resistant mammalian cell lines. Nature 316: 817?819, 1985","journal-title":"Nature"},{"key":"CR19","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1038\/299061a0","volume":"299","author":"Favera R Dalla","year":"1982","unstructured":"Dalla Favera R, Wong Staal F, Gallo RC: Oncogene amplification in promyelocytic leukemia cell line HL-60 and primary leukemic cells of the same patient. Nature 299: 61?63, 1982","journal-title":"Nature"},{"key":"CR20","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1038\/298343a0","volume":"298","author":"E Santos","year":"1982","unstructured":"Santos E, Tronick SR, Aaronson SA, Pulciani S, Barbacid M: T24 human bladder carcinoma oncogene is an activated form of the normal human homologue of Balb and Harvey-MSV transforming genes. Nature 298: 343?347, 1982","journal-title":"Nature"},{"key":"CR21","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1111\/j.1365-2141.1984.tb06095.x","volume":"58","author":"R Galanello","year":"1984","unstructured":"Galanello R, Maccioni L, Ruggeri R, Perseu L, Cao A: Alpha thalassaemia in Sardinian newborns. Br J Haematol 58: 361?368, 1984","journal-title":"Br J Haematol"},{"key":"CR22","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1016\/0014-2964(73)90055-8","volume":"9","author":"EORTC Breast Cancer Cooperative Group","year":"1973","unstructured":"EORTC Breast Cancer Cooperative Group: Standards for the assessment of estrogen receptors in human breast cancer. Eur J Cancer 9: 379?381, 1973","journal-title":"Eur J Cancer"},{"key":"CR23","first-page":"2943","volume":"50","author":"HS Smith","year":"1990","unstructured":"Smith HS, Zoli W, Volpi A, Miller A, Lippman M, Swain S, Mayall B, Dollbaum C, Hackett AJ, Amadori D: Preliminary correlations of clinical outcome within vitro chemosensitivity of second passage human breast cancer cells. Cancer Res 50: 2943?2948, 1990","journal-title":"Cancer Res"}],"container-title":["Breast Cancer Research and Treatment"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF00666586.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/BF00666586\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF00666586","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,4,5]],"date-time":"2019-04-05T03:33:38Z","timestamp":1554435218000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/BF00666586"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1993,1]]},"references-count":23,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1993,1]]}},"alternative-id":["BF00666586"],"URL":"https:\/\/doi.org\/10.1007\/bf00666586","relation":{},"ISSN":["0167-6806","1573-7217"],"issn-type":[{"value":"0167-6806","type":"print"},{"value":"1573-7217","type":"electronic"}],"subject":[],"published":{"date-parts":[[1993,1]]}}}