{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,21]],"date-time":"2025-09-21T18:06:53Z","timestamp":1758478013538},"reference-count":30,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[1988,1,1]],"date-time":"1988-01-01T00:00:00Z","timestamp":567993600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acta Neuropathol"],"published-print":{"date-parts":[[1988]]},"DOI":"10.1007\/bf00688097","type":"journal-article","created":{"date-parts":[[2004,11,28]],"date-time":"2004-11-28T15:33:50Z","timestamp":1101656030000},"page":"135-141","source":"Crossref","is-referenced-by-count":36,"title":["Variability in the activity of respiratory chain enzymes in mitochondrial myopathies"],"prefix":"10.1007","volume":"76","author":[{"given":"Y.","family":"Koga","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"I.","family":"Nonaka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N.","family":"Sunohara","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"Yamanaka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K.","family":"Kumagai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"CR1","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1038\/290457a0","volume":"290","author":"S Anderson","year":"1981","unstructured":"Anderson S, Bankier AT, Barrell BG, de Bruijn MHL, Coulson AR, Drouin J, Eperon IC, Nierlich DP, Roe BA, Sanger F, Schreier PH, Smith AJH, Staden R, Young IG (1981) Sequence and organization of the human mitochondrial genome. Nature 290:457?465","journal-title":"Nature"},{"key":"CR2","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1007\/BF00442753","volume":"143","author":"AW Behbehani","year":"1984","unstructured":"Behbehani AW, Goebel H, Osse G, Gabriel M, Langenbeck U, Berden J, Berger R, Schutgens RBH (1984) Mitochondrial myopathy with lactic acidosis and deficient activity of muscle succinate cytochromec oxidoreductase. Eur J Pediatr 143:67?71","journal-title":"Eur J Pediatr"},{"key":"CR3","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1002\/ana.410010104","volume":"1","author":"RA Berenberg","year":"1977","unstructured":"Berenberg RA, Pellock JM, DiMauro S (1977) Lumping or splitting? ?Ophthalmoplegia-plus? or Kearns-Sayre syndrome? Ann Neurol 1:37?54","journal-title":"Ann Neurol"},{"key":"CR4","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1016\/0006-2944(78)90037-6","volume":"19","author":"H Bookelman","year":"1978","unstructured":"Bookelman H, Trijbels JMF, Sengers RCA, Janssen AJM (1978) Measurement of cytochromes in human skeletal muscle mitochondria isolated from fresh and frozen stored muscle specimens. Biochem Med 19:366?373","journal-title":"Biochem Med"},{"key":"CR5","doi-asserted-by":"crossref","first-page":"802","DOI":"10.1212\/WNL.35.6.802","volume":"35","author":"N Bresolin","year":"1985","unstructured":"Bresolin N, Zeviani M, Bonilla E, Miller RH, Leech RW, Shanske S, Nakagawa M, DiMauro S (1985) Fatal infantile cytochromec oxidase deficiency: decrease of immunologically detectable enzyme in muscle. Neurology 35:802?812","journal-title":"Neurology"},{"key":"CR6","doi-asserted-by":"crossref","first-page":"564","DOI":"10.1002\/ana.410210607","volume":"21","author":"N Bresolin","year":"1987","unstructured":"Bresolin N, Moggio M, Bet L, Gallanti A, Prelle A, Nobile-Orazio E, Adobbati L, Ferrante C, Pellegrini G, Scarlato G (1987) Progressive cytochromec oxidase deficiency in a case of Kearns-Sayre syndrome: morphological, immunological, and biochemical studies in muscle biopsies and autopsy tissues. Ann Neurol 21:564?572","journal-title":"Ann Neurol"},{"key":"CR7","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1001\/archneur.1970.00480280083010","volume":"23","author":"MH Brooke","year":"1970","unstructured":"Brooke MH, Kaiser KK (1970) Muscle fiber types: how many and what kind? Arch Neurol 23:369?379","journal-title":"Arch Neurol"},{"key":"CR8","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1002\/ana.410140209","volume":"14","author":"S DiMauro","year":"1983","unstructured":"DiMauro S, Nicholson JF, Hays AP, Eastwood AB, Papadimitriou A, Koenigsberger R, DeVivo DC (1983) Benign infantile mitochondrial myopathy due to reversible cytochromec oxidase deficiency. Ann Neurol 14:226?234","journal-title":"Ann Neurol"},{"key":"CR9","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1002\/ana.410170602","volume":"17","author":"S DiMauro","year":"1985","unstructured":"DiMauro S, Bonilla E, Zeviani M, Nakagawa M, DeVivo DC (1985) Mitochondrial myopathies. Ann Neurol 17:521?538","journal-title":"Ann Neurol"},{"key":"CR10","first-page":"20","volume-title":"Muscle biopsy, a modern approach","author":"V Dubowitz","year":"1973","unstructured":"Dubowitz V, Brooke MH (1973) Muscle biopsy, a modern approach. Saunders, London Philadelphia Toronto, pp 20?33"},{"key":"CR11","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1056\/NEJM198307213090304","volume":"21","author":"J Egger","year":"1983","unstructured":"Egger J, Wilson J (1983) Mitochondrial inheritance in a mitochondrially mediated disease. N Engl J Med 21:142?146","journal-title":"N Engl J Med"},{"key":"CR12","doi-asserted-by":"crossref","first-page":"919","DOI":"10.1212\/WNL.13.11.919","volume":"13","author":"WK Engel","year":"1963","unstructured":"Engel WK, Cunningham GG (1963) Rapid examination of muscle tissue: an improved trichrome stain method for freshfrozen biopsy sections. Neurology 13:919?923","journal-title":"Neurology"},{"key":"CR13","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/0022-510X(80)90031-3","volume":"47","author":"N Fukuhara","year":"1980","unstructured":"Fukuhara N, Tokiguchi S, Shirakawa S, Tsubaki T (1980) Myoclonus epilepsy associated with ragged-red fibers (mitochondrial abnormalities): disease entity or syndrome? Light and electronmicroscopic studies of two cases and review of the literature. J Neurol Sci 47:117?133","journal-title":"J Neurol Sci"},{"key":"CR14","doi-asserted-by":"crossref","first-page":"6715","DOI":"10.1073\/pnas.77.11.6715","volume":"77","author":"RE Giles","year":"1980","unstructured":"Giles RE, Blanc H, Cann HM, Wallace DC (1980) Maternal inheritance of human mitochondrial DNA. Proc Natl Acad Sci USA 77:6715?6719","journal-title":"Proc Natl Acad Sci USA"},{"key":"CR15","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1620\/tjem.137.329","volume":"137","author":"K Hayasaka","year":"1982","unstructured":"Hayasaka K, Metoki K, Satoh T (1982) Comparison of cytosolic and mitochondrial enzyme alterations in the livers of propionic or methylmalonic acidemia: a reduction of cytochromec oxidase activity. Tohoku J Exp Med 137:329?334","journal-title":"Tohoku J Exp Med"},{"key":"CR16","doi-asserted-by":"crossref","first-page":"1619","DOI":"10.1212\/WNL.33.12.1619","volume":"33","author":"PL Holliday","year":"1983","unstructured":"Holliday PL, Climie RW, Gilroy J, Mahmud MZ (1983) Mitochondrial myopathy and encephalopathy: three cases ? a deficiency of NADH-CoQ dehydrogenase? Neurology 33:1619?1622","journal-title":"Neurology"},{"key":"CR17","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1001\/archneur.1973.00490270044007","volume":"29","author":"F Jerusalem","year":"1973","unstructured":"Jerusalem F, Angelini C, Engel AG Groover RV (1973) Mitochondria-lipid-glycogen disease of muscle. Arch Neurol 29:162?169","journal-title":"Arch Neurol"},{"key":"CR18","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/0022-510X(83)90125-9","volume":"60","author":"MA Johnson","year":"1983","unstructured":"Johnson MA, Turnbull DM, Dick DJ, Sherrat HSA (1983) A partial deficiency of cytochromec oxidase in chronic progressive external ophthalmoplegia. J Neurol Sci 60:31?53","journal-title":"J Neurol Sci"},{"key":"CR19","doi-asserted-by":"crossref","first-page":"991","DOI":"10.1203\/00006450-198410000-00017","volume":"18","author":"NG Kennaway","year":"1984","unstructured":"Kennaway NG, Buist NRM, Darley-Usmar VM, Papadimitriou A, DiMauro S, Kelley RI, Capaldi RA, Blank NK, D'Agostino A (1984) Lactic acidosis and mitochondrial myopathy associated with deficiency of several components of complex III of the respiratory chain. Pediatr Res 18:991?999","journal-title":"Pediatr Res"},{"key":"CR20","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/S0021-9258(19)52451-6","volume":"193","author":"OH Lowry","year":"1951","unstructured":"Lowry OH, Rosenbrough NJ, Farr AL, Randall RJ (1951) Protein measurement with the Folin-phenol reagent. J Biol Chem 193:265?275","journal-title":"J Biol Chem"},{"key":"CR21","doi-asserted-by":"crossref","first-page":"1776","DOI":"10.1172\/JCI104637","volume":"41","author":"R Luft","year":"1962","unstructured":"Luft R, Ikkos D, Palmieri G, Ernster L, Afzelius B (1962) A case of severe hypermetabolism of nonthyroid origin with a defect in the maintenance of mitochondrial respiratory control: a correlated clinical, biochemical, and morphological study. J Clin Invest 41:1776?1804","journal-title":"J Clin Invest"},{"key":"CR22","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1016\/0076-6879(67)10094-3","volume":"10","author":"B Mackler","year":"1967","unstructured":"Mackler B (1967) Microsomal DPNH-cytochromec reductase. Methods Enzymol 10:551?553","journal-title":"Methods Enzymol"},{"key":"CR23","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1172\/JCI111484","volume":"74","author":"RW Moreadith","year":"1984","unstructured":"Moreadith RW, Batshaw ML, Ohnishi T (1984) Deficiency of the iron-sulfur clusters of mitochondrial reduced nicotinamide-adenine dinucleotide-ubiquinone oxidoreductase (complex I) in an infant with congenital lactic acidosis. J Clin Invest 74:685?697","journal-title":"J Clin Invest"},{"key":"CR24","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1093\/brain\/105.3.553","volume":"105","author":"JA Morgan-Hughes","year":"1982","unstructured":"Morgan-Hughes JA, Hayes DJ, Clark JB, Landon DN, Swash M, Stark RJ, Rudge P (1982) Mitochondrial encephalomyopathies. Brain 105:553?582","journal-title":"Brain"},{"key":"CR25","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1093\/oxfordjournals.jbchem.a128243","volume":"58","author":"Y Orii","year":"1965","unstructured":"Orii Y, Okunuki K (1965) Studies on cytochromea. Cytochrome oxidase activity of the Okunuki preparation and its activation by heat, alkali and detergent treatments. J Biochem 58:561?568","journal-title":"J Biochem"},{"key":"CR26","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1002\/ana.410160409","volume":"16","author":"SG Pavlakis","year":"1984","unstructured":"Pavlakis SG, Phillips PC, DiMauro S, DeVivo DC, Rowland LP (1984) Mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes (MELAS): a distinctive clinical syndrome. Ann Neurol 16:481?488","journal-title":"Ann Neurol"},{"key":"CR27","doi-asserted-by":"crossref","first-page":"957","DOI":"10.1001\/archneur.1986.00520090081024","volume":"43","author":"H Reichmann","year":"1986","unstructured":"Reichmann H, Rohkamm R, Zeviani M, Servidei S, Ricker K, DiMauro S (1986) Mitochondrial myopathy due to complex III deficiency with normal reducible cytochromeb concentration. Arch Neurol 43:957?961","journal-title":"Arch Neurol"},{"key":"CR28","doi-asserted-by":"crossref","first-page":"867","DOI":"10.1073\/pnas.62.3.867","volume":"62","author":"MHK Shokeir","year":"1969","unstructured":"Shokeir MHK, Shreffler DC (1969) Cytochrome oxidase deficiency in Wilson's disease; a suggested ceruloplasmin function. Proc Natl Acad Sci USA 62:867?872","journal-title":"Proc Natl Acad Sci USA"},{"key":"CR29","first-page":"235","volume-title":"Mitochondria","author":"A Tzagoloff","year":"1982","unstructured":"Tzagoloff A (1982) Mitochondria, Plenum, New York, pp 235?321"},{"key":"CR30","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1212\/WNL.37.1.64","volume":"37","author":"M Zeviani","year":"1987","unstructured":"Zeviani M, Peterson P, Servidei S, Bonilla E, DiMauro S (1987) Benign reversible muscle cytochromec oxidase deficiency: a second case. Neurology 37:64?67","journal-title":"Neurology"}],"container-title":["Acta Neuropathologica"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF00688097.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/BF00688097\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF00688097","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,6,29]],"date-time":"2021-06-29T23:30:07Z","timestamp":1625009407000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/BF00688097"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1988]]},"references-count":30,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1988]]}},"alternative-id":["BF00688097"],"URL":"https:\/\/doi.org\/10.1007\/bf00688097","relation":{},"ISSN":["0001-6322","1432-0533"],"issn-type":[{"value":"0001-6322","type":"print"},{"value":"1432-0533","type":"electronic"}],"subject":[],"published":{"date-parts":[[1988]]}}}