{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,8]],"date-time":"2026-02-08T17:59:49Z","timestamp":1770573589142,"version":"3.49.0"},"reference-count":53,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[1990,1,1]],"date-time":"1990-01-01T00:00:00Z","timestamp":631152000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Comp Physiol B"],"published-print":{"date-parts":[[1990]]},"DOI":"10.1007\/bf00691715","type":"journal-article","created":{"date-parts":[[2004,11,29]],"date-time":"2004-11-29T04:51:14Z","timestamp":1101703874000},"page":"695-706","source":"Crossref","is-referenced-by-count":31,"title":["On the role of Ca2+-calmodulin-dependent and cAMP-dependent protein phosphorylation in the circadian rhythm ofNeurospora crassa"],"prefix":"10.1007","volume":"159","author":[{"given":"D.","family":"Techel","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.","family":"Gebauer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"W.","family":"Kohler","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T.","family":"Braumann","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B.","family":"Jastorff","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L.","family":"Rensing","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"CR1","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1016\/0003-2697(76)90527-3","volume":"72","author":"MM Bradford","year":"1976","unstructured":"Bradford MM (1976) A rapid and sensitive method for the quantification of microgram quantities of proteins utilizing the principle of protein dye binding. Anal Biochem 72:248?254","journal-title":"Anal Biochem"},{"key":"CR2","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/S0021-9673(01)93510-1","volume":"350","author":"T Braumann","year":"1985","unstructured":"Braumann T, Jastorff B (1985) Physico-chemical characterization of cyclic nucleotides by reversed-phase high-performance liquid chromatography: quantitative determination of hydrophobicity. J Chromatogr 350:105?118","journal-title":"J Chromatogr"},{"key":"CR3","doi-asserted-by":"crossref","first-page":"912","DOI":"10.1111\/j.1471-4159.1986.tb00697.x","volume":"47","author":"T Braumann","year":"1986","unstructured":"Braumann T, Jastorff B, Richter-Landsberg C (1986) Fate of cyclic nucleotides in PC12 cell cultures: uptake, metabolism and effects on nerve growth factor-induced neurite out-growth. J Neurochem 47:912?919","journal-title":"J Neurochem"},{"key":"CR4","first-page":"130","volume":"40","author":"G Cornelius","year":"1986","unstructured":"Cornelius G, Rensing L (1986) Circadian rhythm of heat shock protein synthesis ofNeurospora crassa. Europ J Cell Biol 40:130?132","journal-title":"Europ J Cell Biol"},{"key":"CR5","doi-asserted-by":"crossref","first-page":"852","DOI":"10.1016\/0006-291X(89)92388-7","volume":"162","author":"G Cornelius","year":"1989","unstructured":"Cornelius G, Gebauer G, Techel D (1989) Inositol trisphosphate induces calcium release fromNeurospora crassa vacuoles. Biochem Biophys Res Comm 162:852?856","journal-title":"Biochem Biophys Res Comm"},{"key":"CR6","first-page":"2341","volume":"133","author":"G Cornelius","year":"1987","unstructured":"Cornelius G, Nakashima K (1987) Vacuoles play a decisive role in calcium homeostatis inNeurospora crassa. J Gen Microbiol 133:2341?2347","journal-title":"J Gen Microbiol"},{"key":"CR7","first-page":"3340","volume":"260","author":"G Crynkiewicz","year":"1985","unstructured":"Crynkiewicz G, Poenie M, Tsien RJ (1985) A new generation of Ca2+ indicators with greatly improved fluorescence properties. J Biol Chem 260:3340?3450","journal-title":"J Biol Chem"},{"key":"CR8","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1016\/0076-6879(71)17168-6","volume":"17","author":"RH Davis","year":"1970","unstructured":"Davis RH, de Serres FJ (1970) Genetic and microbiological research techniques forNeurospora crassa. Meth Enzymol 17A:79?143","journal-title":"Meth Enzymol"},{"key":"CR9","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1111\/j.1432-1033.1984.tb08279.x","volume":"142","author":"RJW Wit De","year":"1985","unstructured":"De Wit RJW, Hekstra D, Jastorff B, Stec WJ, Baraniak J, Van Driel R, Van Haastert PJM (1985) Inhibitory action of certain cyclophosphate derivatives of cAMP on cAMP-dependent protein kinases. Eur J Biochem 142:255?260","journal-title":"Eur J Biochem"},{"key":"CR10","doi-asserted-by":"crossref","first-page":"1049","DOI":"10.1104\/pp.63.6.1049","volume":"63","author":"S Dharmanada","year":"1979","unstructured":"Dharmanada S, Feldman J (1979) Spatial distribution of circadian clock phase in aging cultures ofNeurospora crassa. Plant Physiol 63:1049?1054","journal-title":"Plant Physiol"},{"key":"CR11","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1016\/0022-5193(82)90315-0","volume":"94","author":"K Drescher","year":"1982","unstructured":"Drescher K, Cornelius G, Rensing L (1982) Phase response curves obtained by perturbing different variables of a 24-h model oscillator based on translational control. J Theor Biol 94:345?353","journal-title":"J Theor Biol"},{"key":"CR12","doi-asserted-by":"crossref","first-page":"660","DOI":"10.1073\/pnas.79.2.660","volume":"79","author":"A Eskin","year":"1982","unstructured":"Eskin A, Corrent G, Lin CY, McAdoo DJ (1982) Mechanism for shifting the phase of a circadian rhythm by serotonin: Involvement of cAMP. Proc Natl Acad Sci USA 79:660?664","journal-title":"Proc Natl Acad Sci USA"},{"key":"CR13","doi-asserted-by":"crossref","first-page":"2466","DOI":"10.1523\/JNEUROSCI.04-10-02466.1984","volume":"4","author":"A Eskin","year":"1984","unstructured":"Eskin A, Takahashi JS, Zatz M, Block GD (1984) Cyclic guanosine 3?,5? monophosphate mimics the effects of light on a circadian pacemaker in the eye ofAplysia. J Neurosci 4:2466?2471","journal-title":"J Neurosci"},{"key":"CR14","doi-asserted-by":"crossref","first-page":"789","DOI":"10.1126\/science.173018","volume":"190","author":"J Feldman","year":"1975","unstructured":"Feldman J (1975) Circadian periodicity inNeurospora crassa: Alteration by inhibitors of cyclic AMP phosphodiesterase. Science 190:789?790","journal-title":"Science"},{"key":"CR15","unstructured":"Feldman JF, Gardner G, Denison R (1979) Genetic analysis of the circadian clock inNeurospora. In: Suda M, Hayishi O, Nakagawa H (eds) ?Biological rhythms and their control mechanisms?, Amsterdam."},{"key":"CR16","first-page":"319","volume":"7","author":"J Feldman","year":"1983","unstructured":"Feldman J, Dunlap JC (1983)Neurospora crassa: A unique system for studying circadian rhythms. Photochem Photobiol Rev 7:319?368","journal-title":"Photochem Photobiol Rev"},{"issue":"23","key":"CR17","doi-asserted-by":"crossref","first-page":"2803","DOI":"10.1016\/0040-4039(88)85214-6","volume":"29","author":"H-G Genieser","year":"1988","unstructured":"Genieser H-G, Dostmann W, Botteri U, Butt E, Jastorff B (1988) Synthesis of nucleoside 3?,5?-cyclic phosphorothioates by cyclophosphorylation of unprotected nucleosides. Tetrahedron Lett 29(23):2803?2804","journal-title":"Tetrahedron Lett"},{"key":"CR18","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1055\/s-1989-27150","volume":"1","author":"H-G Genieser","year":"1989","unstructured":"Genieser H-G, Butt E, Botteri U, Dostmann W, Jastorff B (1989) Synthesis of the 3?,5?-cyclic phosphates from unprotected nucleosides. Synthesis 1:53?54","journal-title":"Synthesis"},{"key":"CR19","doi-asserted-by":"crossref","first-page":"1284","DOI":"10.1126\/science.2988128","volume":"228","author":"K Goto","year":"1985","unstructured":"Goto K, Laval-Martin D, Edmunds LN Jr (1985) Biochemical modeling of an antonomously oscillatory circadian clock inEuglena. Science 228:1284?1288","journal-title":"Science"},{"key":"CR20","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/0168-9525(87)90231-9","volume":"3","author":"JC Hall","year":"1987","unstructured":"Hall JC, Rosbash M (1987) Genes and biological rhythms. Trends Genet 3:185?191","journal-title":"Trends Genet"},{"key":"CR21","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/0168-9525(87)90231-9","volume":"3","author":"JC Hall","year":"1987","unstructured":"Hall JC, Rosbash M (1987) Genes and biological rhythms. Trends Genet 3:185?191","journal-title":"Trends Genet"},{"key":"CR22","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1007\/BF00434667","volume":"12","author":"L Hasunuma","year":"1987","unstructured":"Hasunuma L, Funadera K, Shinohara Y, Furukawa K, Watanabe M (1987) Circadian oscillation and light-induced changes in the concentration of cyclic nucleotides inNeurospora. Curr Genet 12:127?133","journal-title":"Curr Genet"},{"key":"CR23","volume-title":"Clinical Pharmacology","author":"A Johnson","year":"1986","unstructured":"Johnson A (1986) Clinical Pharmacology St. Bartholomeus Hospital London EC 1A 7BE."},{"key":"CR24","doi-asserted-by":"crossref","first-page":"476","DOI":"10.1111\/j.1749-6632.1987.tb40631.x","volume":"503","author":"F Kippert","year":"1987","unstructured":"Kippert F (1987) Endocytobiotic coordination, intracellular calcium signaling, and the origin of endogenous rhythms. Ann NY Acad Sci 503:476?495","journal-title":"Ann NY Acad Sci"},{"key":"CR25","first-page":"213","volume":"35","author":"CB Klee","year":"1982","unstructured":"Klee CB, Vanaman TC (1982) Calmodulin. Adv Prot Chem 35:213?321","journal-title":"Adv Prot Chem"},{"key":"CR26","doi-asserted-by":"crossref","first-page":"680","DOI":"10.1038\/227680a0","volume":"227","author":"HK Laemmli","year":"1970","unstructured":"Laemmli HK (1970) Cleavage of structural proteins during the assembling of the head of bacteriophage T4. Nature 227:680?685","journal-title":"Nature"},{"key":"CR27","doi-asserted-by":"crossref","first-page":"426","DOI":"10.2307\/3577240","volume":"113","author":"J Landry","year":"1988","unstructured":"Landry J, Cr\u00eate P, Lamarche S, Chr\u00e9tien P (1988) Activation of Ca2+-dependent processes during heat shock: Role in cell thermoresistance. Radiation Res 113:426?436","journal-title":"Radiation Res"},{"key":"CR28","doi-asserted-by":"crossref","first-page":"1338","DOI":"10.1038\/2021338a0","volume":"202","author":"JY Lettvin","year":"1964","unstructured":"Lettvin JY, Pickard WF, Culloch WS, Pitts W (1964) Theory of passive ion flux through axon membrane. Nature 202:1338?1339","journal-title":"Nature"},{"key":"CR29","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1104\/pp.82.1.226","volume":"82","author":"TA Lonergan","year":"1986","unstructured":"Lonergan TA (1986) A possible second role for calmodulin in biological clock-controlled processes inEuglend. Plant Physiol 82:226?229","journal-title":"Plant Physiol"},{"key":"CR30","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1016\/0968-0004(86)90190-8","volume":"II","author":"JG McCormack","year":"1986","unstructured":"McCormack JG, Denton RM (1986) Calcium as second messenger in mitochondria. Trends in Biochem Sci II:258?262","journal-title":"Trends in Biochem Sci"},{"key":"CR31","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1016\/0167-4889(87)90139-X","volume":"927","author":"T Mine","year":"1987","unstructured":"Mine T, Kojima J, Kimura S, Ogata E (1987) Assessment of the role of Ca2+ mobilization from intracellular pool(s), using dantrolene in the glycogenolytic action of and ?-adrenergic stimulation in perfused rat liver. Biochim Biophys Acta 927:229?234","journal-title":"Biochim Biophys Acta"},{"key":"CR32","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1104\/pp.69.3.619","volume":"69","author":"H Nakashima","year":"1981","unstructured":"Nakashima H (1981) A liquid culture method for the biochemical analysis of the circadian clock inNeurospora crassa. Plant Physiol 69:619?623","journal-title":"Plant Physiol"},{"key":"CR33","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1104\/pp.74.2.268","volume":"74","author":"H Nakashima","year":"1984","unstructured":"Nakashima H (1984) Calcium inhibits phase shifting of the circadian conidiation rhythm ofNeurospora crassa by the calcium ionophore A23187. Plant Physiol 74:268?271","journal-title":"Plant Physiol"},{"key":"CR34","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1177\/074873048600100207","volume":"I","author":"J Nakashima","year":"1986","unstructured":"Nakashima J (1986) Phase shifting of the circadian conidiation rhythm inNeurospora crassa by calmodulin antagonists. J Biol Rhythms I:163?169","journal-title":"J Biol Rhythms"},{"key":"CR35","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1016\/0005-2736(87)90422-6","volume":"897","author":"ST Ohnishi","year":"1987","unstructured":"Ohnishi ST (1987) Effects of halothane, caffeine, dantrolene and tetracaine on the calcium permeability of sceletal sarcoplasmatic reticulum of malignant hyperthermic pigs. Biochim Biophys Acta 897:261?268","journal-title":"Biochim Biophys Acta"},{"key":"CR36","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1016\/0076-6879(88)59017-1","volume":"159","author":"LH Parker Botelho","year":"1988","unstructured":"Parker Botelho LH, Rothermel JD, Coombs RV, Jastorff B (1988) cAMP analog antagonists of cAMP aciton. Meth Enzymol 159:159?172","journal-title":"Meth Enzymol"},{"key":"CR37","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1016\/0304-4165(83)90012-0","volume":"758","author":"RO Perez","year":"1983","unstructured":"Perez RO, Tuinen D van, Marme D, Turian G (1983) Calmodulin-stimulated cyclic nucleotide phosphodiesterase fromNeurospora crassa. Biochim Biophys Acta 758:84?87","journal-title":"Biochim Biophys Acta"},{"key":"CR38","doi-asserted-by":"crossref","first-page":"404","DOI":"10.1104\/pp.67.3.404","volume":"67","author":"J Perlman","year":"1981","unstructured":"Perlman J, Nakashima H, Feldman J (1981) Assay and characteristics of circadian rhythmicity in liquid cultures ofNeurospora crassa. Plant Physiol 67:404?407","journal-title":"Plant Physiol"},{"key":"CR39","first-page":"202","volume":"180","author":"JW Putney","year":"1974","unstructured":"Putney JW, Binachi CP (1974) Site of action of dantrolene in frog satorius muscle. J Pharmacol Exper Therap 180:202?212","journal-title":"J Pharmacol Exper Therap"},{"key":"CR40","first-page":"178","volume":"65","author":"D Raeburn","year":"1987","unstructured":"Raeburn D (1987) Calcium entry blocking drugs: Their classification and sites of action in smooth muscle cells. Medical Biol 65:178?180","journal-title":"Medical Biol"},{"key":"CR41","volume-title":"D\u00fcnnschichtchromotographie","author":"K Randerath","year":"1975","unstructured":"Randerath K (1975) D\u00fcnnschichtchromotographie. Verlag Chemie, Weinheim."},{"key":"CR42","doi-asserted-by":"crossref","DOI":"10.1007\/978-3-642-70332-4","volume-title":"Temporal order","author":"L Rensing","year":"1985","unstructured":"Rensing L, Schill W (1985) Perturbation by single and double pulses as analytical tools for analyzing oscillatory mechanisms. In: Rensing L, Jaeger N (eds) Temporal order. Springer, Heidelberg"},{"key":"CR43","doi-asserted-by":"crossref","DOI":"10.1007\/978-3-642-72637-8","volume-title":"Temporal disorder in human oscillatory systems","author":"L Rensing","year":"1987","unstructured":"Rensing L, Schill W (1987) Perturbation of cellular circadian rhythms by light and temperature. In: Rensing L, An der Heiden U, Mackey J (eds) Temporal disorder in human oscillatory systems. Springer, Berlin Heidelberg New York"},{"key":"CR44","volume-title":"Chronobiology and chronomedicine","author":"L Rensing","year":"1987","unstructured":"Rensing L, Techel D, Schr\u00f6der-Lorenz A (1987a) Protein phosphorylation and circadian clock mechanism. In: Hildebrandt G, Moog R, Raschke F (eds) Chronobiology and chronomedicine. P. Lang, Frankfurt"},{"key":"CR45","doi-asserted-by":"crossref","first-page":"543","DOI":"10.3109\/07420528709078546","volume":"4","author":"L Rensing","year":"1987","unstructured":"Rensing L, Bos A, Kroeger J, Cornelius G (1987b). Possible links between circadian rhythm and heat shock response inNeurospora crassa. Chronobiol Intern 4:543?549","journal-title":"Chronobiol Intern"},{"key":"CR46","doi-asserted-by":"crossref","first-page":"1218","DOI":"10.1111\/j.1471-4159.1985.tb05545.x","volume":"45","author":"CH Richter-Landsberg","year":"1985","unstructured":"Richter-Landsberg CH, Jastorff B (1985) In vitro phosphorylation of mictrotubule-associated proteins: differential effects of cyclic AMP analogues. J Neurochem 45:1218?1222","journal-title":"J Neurochem"},{"key":"CR47","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1007\/BF00392374","volume":"170","author":"A Schr\u00f6der-Lorenz","year":"1987","unstructured":"Schr\u00f6der-Lorenz A, Rensing L (1987) Circadian changes in protein synthesis rate and protein phosphorylation in cell-free extracts ofGonyaulax polyedra. Planta 170:7?13","journal-title":"Planta"},{"key":"CR48","doi-asserted-by":"crossref","first-page":"223","DOI":"10.3109\/07420528509055883","volume":"2","author":"R Schulz","year":"1985","unstructured":"Schulz R, Pilatus U, Rensing L (1985) On the role of energy metabolism inNeurospora circadian clock function. Chronobiol Intern 2:223?233","journal-title":"Chronobiol Intern"},{"key":"CR49","doi-asserted-by":"crossref","first-page":"734","DOI":"10.1016\/0076-6879(74)31077-4","volume":"31","author":"NE Tolbert","year":"1974","unstructured":"Tolbert NE (1974) Isolation of subcellular organelles and metabolites on isopyconic sucrose gradients. Meth Enzymol 31:734?746","journal-title":"Meth Enzymol"},{"key":"CR50","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1016\/0014-5793(84)81187-4","volume":"176","author":"D Tuinen van","year":"1984","unstructured":"Tuinen D van, Perez RO, Marme D, Turian G (1984) Calcium, calmodulin-dependent protein phosphorylation inNeurospora crassa. FEBS Letters 176:317?320","journal-title":"FEBS Letters"},{"key":"CR51","doi-asserted-by":"crossref","first-page":"6000","DOI":"10.1016\/S0021-9258(20)65094-3","volume":"257","author":"PL Vaghy","year":"1982","unstructured":"Vaghy PL, Johnson JD, Matlib MA, Wang T, Schwartz A (1982) Selective inhibition of Na2+-induced Ca2+ release from heart mitochondria by diltiazem and certain other Ca2+ antagonist drugs. J Biol Chem 257:6000?6002","journal-title":"J Biol Chem"},{"key":"CR52","doi-asserted-by":"crossref","first-page":"10020","DOI":"10.1016\/S0021-9258(18)90920-8","volume":"259","author":"PJM Haastert Van","year":"1984","unstructured":"Van Haastert PJM, Van Driel R, Jastorff B, Baraniak J, Stec WJ, De Wit RJW (1984) Competitive cAMP antagonists for cAMP-receptor proteins. J Biol Chem 259:10020?10024","journal-title":"J Biol Chem"},{"key":"CR53","doi-asserted-by":"crossref","DOI":"10.1007\/978-3-662-22492-2","volume-title":"The geometry of biological time","author":"AT Winfree","year":"1980","unstructured":"Winfree AT (1980) The geometry of biological time. Springer, Berlin Heidelberg New York"}],"container-title":["Journal of Comparative Physiology B"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF00691715.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/BF00691715\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF00691715","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,16]],"date-time":"2024-01-16T01:02:50Z","timestamp":1705366970000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/BF00691715"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1990]]},"references-count":53,"journal-issue":{"issue":"6","published-print":{"date-parts":[[1990]]}},"alternative-id":["BF00691715"],"URL":"https:\/\/doi.org\/10.1007\/bf00691715","relation":{},"ISSN":["0174-1578","1432-136X"],"issn-type":[{"value":"0174-1578","type":"print"},{"value":"1432-136X","type":"electronic"}],"subject":[],"published":{"date-parts":[[1990]]}}}