{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T03:13:10Z","timestamp":1761016390965},"reference-count":24,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[1985,2,1]],"date-time":"1985-02-01T00:00:00Z","timestamp":476064000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Naunyn-Schmiedeberg's Arch. Pharmacol."],"published-print":{"date-parts":[[1985,2]]},"DOI":"10.1007\/bf00692917","type":"journal-article","created":{"date-parts":[[2004,11,30]],"date-time":"2004-11-30T08:06:26Z","timestamp":1101801986000},"page":"464-466","source":"Crossref","is-referenced-by-count":30,"title":["Competitive interactions between Bay K 8644 and nifedipine in K+ depolarized smooth muscle: a passive role for Ca2+?"],"prefix":"10.1007","volume":"328","author":[{"given":"Michael","family":"Spedding","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"CR1","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1111\/j.1476-5381.1981.tb09958.x","volume":"74","author":"N Akaike","year":"1981","unstructured":"Akaike N, Brown AM, Nishi K, Tsuda Y (1981) Actions of verapamil, diltiazem and other divalent cations on the calcium current of Helix neurones. Br J Pharmacol 74:87?95","journal-title":"Br J Pharmacol"},{"key":"CR2","doi-asserted-by":"crossref","first-page":"1186","DOI":"10.1111\/j.1471-4159.1984.tb12729.x","volume":"42","author":"U Albus","year":"1984","unstructured":"Albus U, Habermann E, Ferry DR, Glossmann H (1984) Novel 1,4-dihydropyridine (Bay K 8644) facilitates calcium-dependent (3H) noradrenaline release from PC12 cells. J Neurochem 42:1186?1189","journal-title":"J Neurochem"},{"key":"CR3","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1111\/j.1476-5381.1959.tb00928.x","volume":"14","author":"O Arunlakshana","year":"1959","unstructured":"Arunlakshana O, Schild HO (1959) Some quantitative uses of drug antagonists. Br J Pharmacol Chemother 14:48?58","journal-title":"Br J Pharmacol Chemother"},{"key":"CR4","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1016\/0014-5793(84)80838-8","volume":"167","author":"P Bellemann","year":"1984","unstructured":"Bellemann P (1984) Binding properties of a novel calcium channel activating dihydropyridine in monolayer cultures of beating myocytes. FEBS letters 167:88?92","journal-title":"FEBS letters"},{"key":"CR5","first-page":"291","volume":"225","author":"GT Bolger","year":"1983","unstructured":"Bolger GT, Gengo P, Klockowski E, Luchowski E, Siegel H, Janis RA, Triggle AM, Triggle DJ (1983) Characterization of binding of the Ca2+ channel antagonist, (3H) nitrendipine, to guineapig ileal smooth muscle. J Pharmacol Exp Ther 225:291?309","journal-title":"J Pharmacol Exp Ther"},{"key":"CR6","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1016\/0165-6147(82)91221-4","volume":"3","author":"H Glossmann","year":"1982","unstructured":"Glossmann H, Ferry DR, L\u00fcbbecke F, Mewes R, Hofmann F (1982) Calcium channels: direct identification with radioligand binding studies. Trends Pharmacol Sci 3:431?437","journal-title":"Trends Pharmacol Sci"},{"key":"CR7","doi-asserted-by":"crossref","first-page":"5122","DOI":"10.1073\/pnas.80.16.5122","volume":"80","author":"RJ Gould","year":"1983","unstructured":"Gould RJ, Murphy KMM, Reynolds IJ, Snyder SH (1983) Antischizophrenic drugs of the diphenylbutylpiperidine type act as calcium channel antagonists. Proc Natl Acad Sci USA 80:5122?5125","journal-title":"Proc Natl Acad Sci USA"},{"key":"CR8","first-page":"672","volume":"180","author":"G Haeusler","year":"1972","unstructured":"Haeusler G (1972) Differential effects of verapamil on excitation-contraction coupling in smooth muscle and on excitation-secretion coupling in adrenergic nerve terminals. J Pharmacol Exp Ther 180:672?682","journal-title":"J Pharmacol Exp Ther"},{"key":"CR9","doi-asserted-by":"crossref","first-page":"3499","DOI":"10.1016\/0006-2952(83)90295-2","volume":"32","author":"RA Janis","year":"1983","unstructured":"Janis RA, Scriabine A (1983) Sites of action of Ca2+ inhibitors. Biochem Pharmacol 32:3499?3507","journal-title":"Biochem Pharmacol"},{"key":"CR10","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1007\/BF00497671","volume":"323","author":"M Kohlhardt","year":"1983","unstructured":"Kohlhardt M (1983) Saturation characteristics, Ca2+ ions and drug-induced block of cardiac Isi-mediated action potentials. Naunyn-Schmiedeberg's Arch Pharmacol 323:251?260","journal-title":"Naunyn-Schmiedeberg's Arch Pharmacol"},{"key":"CR11","doi-asserted-by":"crossref","first-page":"790","DOI":"10.1038\/302790a0","volume":"302","author":"KS Lee","year":"1983","unstructured":"Lee KS, Tsien RW (1983) Mechanism of calcium channel blockade by verapamil, D 600, diltiazem and nitrendipine in single dialysed heart cells. Nature 302:790?794","journal-title":"Nature"},{"key":"CR12","doi-asserted-by":"crossref","first-page":"1575","DOI":"10.1016\/0024-3205(82)90049-2","volume":"31","author":"PJ Marangos","year":"1982","unstructured":"Marangos PJ, Patel J, Miller C, Martino AM (1982) Specific calcium antagonist sites in brain. Life Sci 31:1575?1585","journal-title":"Life Sci"},{"key":"CR13","doi-asserted-by":"crossref","first-page":"851","DOI":"10.1016\/S0006-291X(84)80185-0","volume":"120","author":"C Montiel","year":"1984","unstructured":"Montiel C, Artalejo AR, Garcia AG (1984) Effect of the novel dihydropyridine Bay K 8644 on adrenomedullary catecholamine release evoked by calcium reintroduction. Biochem Biophys Res Comm 120:851?857","journal-title":"Biochem Biophys Res Comm"},{"key":"CR14","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1007\/BF00586921","volume":"351","author":"J Riemer","year":"1974","unstructured":"Riemer J, D\u00f6rfler F, Mayer C-J, Ulbrecht G (1974) Calcium antagonistic effects on the spontaneous activity of guinea-pig taenia coli. Pfl\u00fcgers Arch 351:33?37","journal-title":"Pfl\u00fcgers Arch"},{"key":"CR15","first-page":"448","volume":"43","author":"JG Sarmiento","year":"1984","unstructured":"Sarmiento JG, Janis RA, Rampe D, Triggle DJ (1984) (3H) Bay K 8644, a calcium channel agonist, binds to high and low affinity sites on membranes from cardiac muscle and brain. Fed Proc 43:448","journal-title":"Fed Proc"},{"key":"CR16","unstructured":"Schramm M, Towart R (1984) Modulation of calcium channel function with 1,4-dihydropyridine structure. J Physiol (Lond) 349:53P"},{"key":"CR17","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1038\/303535a0","volume":"309","author":"M Schramm","year":"1983","unstructured":"Schramm M, Thomas G, Towart R, Franckowiak G (1983a) Novel dihydropyridines with positive inotropic action through activation of Ca2+ channels. Nature 309:535?537","journal-title":"Nature"},{"key":"CR18","first-page":"1268","volume":"33","author":"M Schramm","year":"1983","unstructured":"Schramm M, Thomas G, Towart R, Franckowiak G (1983b). Activation of calcium channels by novel 1,4-dihydropyridines. A new mechanism for positive inotropics or smooth muscle stimulants. Arzneim-Forsch 33:1268?1272","journal-title":"Arzneim-Forsch"},{"key":"CR19","unstructured":"Spedding M (1981) Marked differences in the effects of ?Ca2+-antagonists? on CaCl2-induced contractions in K+-depolarized smooth muscle. Br J Pharmacol 72:144P"},{"key":"CR20","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1007\/BF00500485","volume":"318","author":"M Spedding","year":"1982","unstructured":"Spedding M (1982) Assessment of ?Ca2+-antagonist.? effects of drugs in K+-depolarized smooth muscle. Differentiation of antagonist subgroups. Naunyn-Schmiedeberg's Arch Pharmacol 318:234?240","journal-title":"Naunyn-Schmiedeberg's Arch Pharmacol"},{"key":"CR21","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1111\/j.1476-5381.1983.tb10516.x","volume":"79","author":"M Spedding","year":"1983","unstructured":"Spedding M (1983) Direct inhibitory effects of some ?calcium antagonists? and trifluoperazine on the contractile proteins in smooth muscle. Br J Pharmacol 79:225?231","journal-title":"Br J Pharmacol"},{"key":"CR22","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1007\/BF00496109","volume":"328","author":"M Spedding","year":"1984","unstructured":"Spedding M, Berg C (1984) Interactions between a ?calcium channel agonist? Bay K 8644, and calcium antagonists differentiate calcium antagonist subgroups in K+-depolarized smooth muscle. Naunyn-Schmiedeberg's Arch Pharmacol 328:69?75","journal-title":"Naunyn-Schmiedeberg's Arch Pharmacol"},{"key":"CR23","first-page":"550","volume":"43","author":"CM Su","year":"1984","unstructured":"Su CM, Triggle DJ, Janis RA (1984) Bay K 8644, a calcium channel activator in smooth muscle. Fed Proc 43:550","journal-title":"Fed Proc"},{"key":"CR24","doi-asserted-by":"crossref","DOI":"10.1037\/11774-000","volume-title":"Statistical principles in experimental design","author":"BJ Winer","year":"1962","unstructured":"Winer BJ (1962) Statistical principles in experimental design. McGraw Hill, New York"}],"container-title":["Naunyn-Schmiedeberg's Archives of Pharmacology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF00692917.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/BF00692917\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF00692917","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,4,9]],"date-time":"2019-04-09T18:41:53Z","timestamp":1554835313000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/BF00692917"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1985,2]]},"references-count":24,"journal-issue":{"issue":"4","published-print":{"date-parts":[[1985,2]]}},"alternative-id":["BF00692917"],"URL":"https:\/\/doi.org\/10.1007\/bf00692917","relation":{},"ISSN":["0028-1298","1432-1912"],"issn-type":[{"value":"0028-1298","type":"print"},{"value":"1432-1912","type":"electronic"}],"subject":[],"published":{"date-parts":[[1985,2]]}}}