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This allowed prenatal monitoring to be made for two fetuses in each family, using polymerase chain reaction (PCR), followed by allele\u2010specific oligonucleotide hybridization or<jats:italic>Taq<\/jats:italic>I digestion of amplified sequence. The diagnoses showed heterozygotes of a wild type gene and the corresponding mutant gene in these fetuses; each was confirmed postnatally.<\/jats:p>","DOI":"10.1007\/bf00711312","type":"journal-article","created":{"date-parts":[[2004,11,30]],"date-time":"2004-11-30T08:37:33Z","timestamp":1101803853000},"page":"31-38","source":"Crossref","is-referenced-by-count":12,"title":["Prenatal monitoring of ornithine transcarbamoylase deficiency in two families by DNA analysis"],"prefix":"10.1002","volume":"16","author":[{"given":"T.","family":"Matsuura","sequence":"first","affiliation":[{"name":"Department of Pediatrics Kumamoto University School of Medicine  Kumamoto 860 Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"Hoshide","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Kumamoto University School of Medicine  Kumamoto 860 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