{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,21]],"date-time":"2026-02-21T03:04:38Z","timestamp":1771643078650,"version":"3.50.1"},"reference-count":34,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[1992,1,1]],"date-time":"1992-01-01T00:00:00Z","timestamp":694224000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Europ. J. Appl. Physiol."],"published-print":{"date-parts":[[1992]]},"DOI":"10.1007\/bf00717952","type":"journal-article","created":{"date-parts":[[2004,12,2]],"date-time":"2004-12-02T15:37:20Z","timestamp":1102001840000},"page":"145-152","source":"Crossref","is-referenced-by-count":82,"title":["The respiratory system as an exercise limiting factor in normal sedentary subjects"],"prefix":"10.1007","volume":"64","author":[{"given":"Urs","family":"Boutellier","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paul","family":"Piwko","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"CR1","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1152\/jappl.1989.66.2.529","volume":"66","author":"SR Akabas","year":"1989","unstructured":"Akabas SR, Bazzy AR, di Mauro S, Haddad GG (1989) Metabolic functional adaptation of the diaphragm to training with resistive loads. J Appl Physiol 66: 529?535","journal-title":"J Appl Physiol"},{"key":"CR2","doi-asserted-by":"crossref","first-page":"1759","DOI":"10.1152\/jappl.1989.67.5.1759","volume":"67","author":"JD Anholm","year":"1989","unstructured":"Anholm JD, Stray-Gundersen J, Ramanathan M, Johnson RL Jr (1989) Sustained maximal ventilation after endurance exercise in athletes. J Appl Physiol 67: 1759?1763","journal-title":"J Appl Physiol"},{"key":"CR3","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1152\/jappl.1973.34.1.128","volume":"34","author":"WL Beaver","year":"1973","unstructured":"Beaver WL, Wasserman K, Whipp BJ (1973) On-line computer analysis and breath-by-breath graphical display of exercise function tests. J Appl Physiol 34: 128?132","journal-title":"J Appl Physiol"},{"key":"CR4","doi-asserted-by":"crossref","first-page":"899","DOI":"10.1152\/jappl.1988.64.3.899","volume":"64","author":"MJ Belman","year":"1988","unstructured":"Belman MJ, Gaesser GA (1988) Ventilatory muscle training in the elderly. J Appl Physiol 64: 899?905","journal-title":"J Appl Physiol"},{"key":"CR5","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/0034-5687(86)90066-6","volume":"66","author":"U Boutellier","year":"1986","unstructured":"Boutellier U, Farhi LE (1986) Influence of breathing frequency and tidal volume on cardiac output. Respir Physiol 66: 123?133","journal-title":"Respir Physiol"},{"key":"CR6","first-page":"31","volume":"4","author":"U Boutellier","year":"1982","unstructured":"Boutellier U, Gomez U, Koller EA (1982) Verbessertes Atmungsanalysesystem: Anwendung am Beispiel der Sauerstoffaufnahmekinetik ( $$\\dot VO_2 $$ ). Swiss Med 4: 31?33","journal-title":"Swiss Med"},{"key":"CR7","doi-asserted-by":"crossref","first-page":"837","DOI":"10.1152\/jappl.1987.62.2.837","volume":"62","author":"U Boutellier","year":"1987","unstructured":"Boutellier U, K\ufffdndig T, Gomez U, Pietsch P, Koller EA (1987) Respiratory phase detection and delay determination for breath-by-breath analysis. J Appl Physiol 62: 837?843","journal-title":"J Appl Physiol"},{"key":"CR8","doi-asserted-by":"crossref","first-page":"885","DOI":"10.1152\/jappl.1978.45.6.885","volume":"45","author":"ME Bradley","year":"1978","unstructured":"Bradley ME, Leith DE (1978) Ventilatory muscle training and the oxygen cost of sustained hyperpnea. J Appl Physiol 45: 885?892","journal-title":"J Appl Physiol"},{"key":"CR9","first-page":"1327","volume":"95","author":"A B\ufffdhlmann","year":"1965","unstructured":"B\ufffdhlmann A (1965) Klinische Funktionspr\ufffdfung des Herzens. Schweiz Med Wochenschr 95: 1327?1332","journal-title":"Schweiz Med Wochenschr"},{"key":"CR10","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1146\/annurev.ph.45.030183.002255","volume":"45","author":"PTP Bye","year":"1983","unstructured":"Bye PTP, Farkas GA, Roussos C (1983) Respiratory factors limiting exercise. Ann Rev Physiol 45: 439?451","journal-title":"Ann Rev Physiol"},{"key":"CR11","doi-asserted-by":"crossref","first-page":"948","DOI":"10.1152\/jappl.1986.61.3.948","volume":"61","author":"SF Davies","year":"1986","unstructured":"Davies SF, Iber C, Keene SA, McArthur CD, Path MJ (1986) Effect of respiratory alkalosis during exercise on blood lactate. J Appl Physiol 61: 948?952","journal-title":"J Appl Physiol"},{"key":"CR12","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1152\/jappl.1973.35.3.361","volume":"35","author":"M Demedts","year":"1973","unstructured":"Demedts M, Anthonisen NR (1973) Effects of increased external airway resistance during steady-state exercise. J Appl Physiol 35: 361?366","journal-title":"J Appl Physiol"},{"key":"CR13","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1249\/00005768-198604000-00001","volume":"18","author":"JA Dempsey","year":"1986","unstructured":"Dempsey JA (1986) Is the lung built for exercise? Med Sci Sports Exerc 18: 143?155","journal-title":"Med Sci Sports Exerc"},{"key":"CR14","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1113\/jphysiol.1984.sp015412","volume":"355","author":"JA Dempsey","year":"1984","unstructured":"Dempsey JA, Hanson PG, Henderson KS (1984) Exercise-induced arterial hypoxaemia in healthy human subjects at sea level. J Physiol (Lond) 355: 161?175","journal-title":"J Physiol (Lond)"},{"key":"CR15","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1016\/0034-5687(90)90075-A","volume":"80","author":"PE Prampero di","year":"1990","unstructured":"di Prampero PE, Ferretti G (1990) Factors limiting maximal oxygen consumption in humans. Respir Physiol 80: 113?128","journal-title":"Respir Physiol"},{"issue":"Suppl 1","key":"CR16","doi-asserted-by":"crossref","first-page":"S15","DOI":"10.1055\/s-2007-1024848","volume":"11","author":"G Ferretti","year":"1990","unstructured":"Ferretti G, Boutellier U, Pendergast DR, Moia C, Minetti AE, Howald H, di Prampero PE (1990) Oxygen transport system before and after exposure to chronic hypoxia. Int J Sports Med 11 [Suppl 1]: S15-S20","journal-title":"Int J Sports Med"},{"key":"CR17","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1136\/thx.38.1.50","volume":"38","author":"S Freedman","year":"1983","unstructured":"Freedman S, Cooke NT, Moxham J (1983) Production of lactic acid by respiratory muscles. Thorax 38: 50?54","journal-title":"Thorax"},{"key":"CR18","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1146\/annurev.me.35.020184.003205","volume":"35","author":"A Grassino","year":"1984","unstructured":"Grassino A, Macklem PT (1984) Respiratory muscle fatigue and ventilatory failure. Ann Rev Med 35: 625?647","journal-title":"Ann Rev Med"},{"key":"CR19","doi-asserted-by":"crossref","first-page":"1393","DOI":"10.1152\/jappl.1990.68.4.1393","volume":"68","author":"JM Hagberg","year":"1990","unstructured":"Hagberg JM, King DS, Rogers MA, Montain SJ, Jilka SM, Kohrt WM, Heller SL (1990) Exercise and recovery ventilatory and $$\\dot VO_2 $$ responses of patients with McArdle's disease. J Appl Physiol 68: 1393?1398","journal-title":"J Appl Physiol"},{"key":"CR20","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1172\/JCI103603","volume":"37","author":"WE Huckabee","year":"1958","unstructured":"Huckabee WE (1958) Relationships of pyruvate and lactate during anaerobic metabolism. I. Effects of infusion of pyruvate or glucose and of hyperventilation. J Clin Invest 37: 244?254","journal-title":"J Clin Invest"},{"key":"CR21","first-page":"274","volume":"124","author":"J Jardim","year":"1981","unstructured":"Jardim J, Farkas G, Prefaut C, Thomas D, Macklem PT, Roussos C (1981) The failing inspiratory muscles under normoxic and hypoxic conditions. Am Rev Respir Dis 124: 274?279","journal-title":"Am Rev Respir Dis"},{"key":"CR22","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1159\/000195735","volume":"55","author":"R Jeyaranjan","year":"1989","unstructured":"Jeyaranjan R, Goode R, Duffin J (1989) Role of lactic acidosis in the ventilatory response to heavy exercise. Respiration 55: 202?209","journal-title":"Respiration"},{"key":"CR23","first-page":"853","volume":"116","author":"TG Keens","year":"1977","unstructured":"Keens TG, Krastins IRB, Wannamaker EM, Levison H, Crozier DN, Bryan AC (1977) Ventilatory muscle endurance training in normal subjects and patients with cystic fibrosis. Am Rev Respir Dis 116: 853?860","journal-title":"Am Rev Respir Dis"},{"key":"CR24","doi-asserted-by":"crossref","first-page":"508","DOI":"10.1152\/jappl.1976.41.4.508","volume":"41","author":"DE Leith","year":"1976","unstructured":"Leith DE, Bradley M (1976) Ventilatory muscle strength and endurance training. J Appl Physiol 41: 508?516","journal-title":"J Appl Physiol"},{"key":"CR25","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1152\/jappl.1973.34.2.233","volume":"34","author":"DA Lieberman","year":"1973","unstructured":"Lieberman DA, Faulkner JA, Craig AB Jr, Maxwell LC (1973) Performance and histochemical composition of guinea pig and human diaphragm. J Appl Physiol 34: 233?237","journal-title":"J Appl Physiol"},{"key":"CR26","doi-asserted-by":"crossref","first-page":"1581","DOI":"10.1152\/jappl.1982.52.6.1581","volume":"52","author":"B Martin","year":"1982","unstructured":"Martin B, Heintzelman M, Chen H-I (1982) Exercise performance after ventilatory work. J Appl Physiol 52: 1581?1585","journal-title":"J Appl Physiol"},{"key":"CR27","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1249\/00005768-198104000-00002","volume":"13","author":"BJ Martin","year":"1981","unstructured":"Martin BJ, Stager JM (1981) Ventilatory endurance in athletes and non-athletes. Med Sci Sport Exerc 13: 21?26","journal-title":"Med Sci Sport Exerc"},{"key":"CR28","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1055\/s-2008-1025647","volume":"8","author":"DW Morgan","year":"1987","unstructured":"Morgan DW, Kohrt WM, Bates BJ, Skinner JS (1987) Effects of respiratory muscle endurance training on ventilatory and endurance performance of moderately trained cyclists. Int J Sports Med 8: 88?93","journal-title":"Int J Sports Med"},{"key":"CR29","doi-asserted-by":"crossref","first-page":"874","DOI":"10.1152\/jappl.1969.27.6.874","volume":"27","author":"Y Ouellet","year":"1969","unstructured":"Ouellet Y, Poh SC, Becklake MR (1969) Circulatory factors limiting maximal aerobic exercise capacity. J Appl Physiol 27: 874?880","journal-title":"J Appl Physiol"},{"key":"CR30","first-page":"201","volume-title":"Clinical cardiopulmonary physiology","author":"T Sj\ufffdstrand","year":"1960","unstructured":"Sj\ufffdstrand T (1960) Functional capacity and exercise tolerance in patients with impaired cardiovascular function. In: Gordon BL, Kory RC (eds), Clinical cardiopulmonary physiology. Grune and Stratton, New York, pp 201?219"},{"key":"CR31","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1152\/jappl.1991.70.1.216","volume":"70","author":"A Tarasiuk","year":"1991","unstructured":"Tarasiuk A, Scharf SM, Miller MJ (1991) Effect of chronic resistive loading on inspiratory muscles in rats. J Appl Physiol 70: 216?222","journal-title":"J Appl Physiol"},{"key":"CR32","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/0034-5687(68)90086-8","volume":"5","author":"SM Tenney","year":"1968","unstructured":"Tenney SM, Reese RE (1968) The ability to sustain great breathing efforts. Respir Physiol 5: 187?201","journal-title":"Respir Physiol"},{"key":"CR33","first-page":"6","volume":"2","author":"PD Wagner","year":"1987","unstructured":"Wagner PD (1987) The lungs during exercise. News Physiol Sci 2: 6?10","journal-title":"News Physiol Sci"},{"key":"CR34","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1249\/00005768-198604000-00004","volume":"18","author":"JH Williams","year":"1986","unstructured":"Williams JH, Powers SK, Stuart MK (1986) Hemoglobin desaturation in highly trained athletes during heavy exercise. Med Sci Sports Exerc 18: 168?173","journal-title":"Med Sci Sports Exerc"}],"container-title":["European Journal of Applied Physiology and Occupational Physiology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF00717952.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/BF00717952\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF00717952","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,4,5]],"date-time":"2019-04-05T10:51:43Z","timestamp":1554461503000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/BF00717952"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1992]]},"references-count":34,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1992]]}},"alternative-id":["BF00717952"],"URL":"https:\/\/doi.org\/10.1007\/bf00717952","relation":{},"ISSN":["0301-5548","1439-6327"],"issn-type":[{"value":"0301-5548","type":"print"},{"value":"1439-6327","type":"electronic"}],"subject":[],"published":{"date-parts":[[1992]]}}}