{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T11:40:55Z","timestamp":1791286855830,"version":"4.1.0"},"reference-count":36,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[1993,4,1]],"date-time":"1993-04-01T00:00:00Z","timestamp":733622400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatr Nephrol"],"published-print":{"date-parts":[[1993,4]]},"DOI":"10.1007\/bf00864387","type":"journal-article","created":{"date-parts":[[2005,1,8]],"date-time":"2005-01-08T15:06:43Z","timestamp":1105196803000},"page":"163-172","source":"Crossref","is-referenced-by-count":90,"title":["Renal and biliary abnormalities in a new murine model of autosomal recessive polycystic kidney disease"],"prefix":"10.1007","volume":"7","author":[{"given":"Jeroen","family":"Nauta","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuko","family":"Ozawa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"suffix":"Jr","given":"William E.","family":"Sweeney","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joe C.","family":"Rutledge","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ellis D.","family":"Avner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"BF00864387_CR1","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1097\/00005792-197107000-00003","volume":"50","author":"E Lieberman","year":"1971","unstructured":"Lieberman E (1971) Infantile polycystic disease of the kidneys and liver: clinical, pathological and radiological correlations and comparison with congenital hepatic fibrosis. Medicine (Baltimore) 50: 277\u2013318","journal-title":"Medicine (Baltimore)"},{"key":"BF00864387_CR2","first-page":"477","volume":"164","author":"IM Murray-Lyon","year":"1972","unstructured":"Murray-Lyon IM, Shilkin KB, Laws JW, Illing RC, Williams R (1972) Non-obstructive dilatation of the intrahepatic biliary tract with cholangitis. Q J Med 164: 477\u2013489","journal-title":"Q J Med"},{"key":"BF00864387_CR3","doi-asserted-by":"crossref","first-page":"370","DOI":"10.1016\/S0022-3476(81)80320-4","volume":"99","author":"F Alvarez","year":"1981","unstructured":"Alvarez F, Bernard O, Brunelle F, Hadchouel M, Leblanc A, Odi\u00e8vre M, Alagille D (1981) Congenital hepatic fibrosis in children. J Pediatr 99: 370\u2013375","journal-title":"J Pediatr"},{"key":"BF00864387_CR4","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1007\/BF00859625","volume":"3","author":"BS Kaplan","year":"1989","unstructured":"Kaplan BS, Fay J, Shah V, Dillon MJ, Barratt TM (1989) Autosomal recessive polycystic kidney disease. Pediatr Nephrol 3: 43\u201349","journal-title":"Pediatr Nephrol"},{"key":"BF00864387_CR5","first-page":"632","volume":"11","author":"R McDonald","year":"1991","unstructured":"McDonald R, Avner ED (1991) Cystic disease in children. Semin Nephrol 11: 632\u2013642","journal-title":"Semin Nephrol"},{"key":"BF00864387_CR6","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1136\/jmg.8.3.257","volume":"8","author":"H Blyth","year":"1971","unstructured":"Blyth H, Ockenden BG (1971) Polycystic disease of kidneys and liver presenting in childhood. J Med Genet 8: 257\u2013284","journal-title":"J Med Genet"},{"key":"BF00864387_CR7","first-page":"371","volume-title":"Pediatric nephrology","author":"J Resnick","year":"1987","unstructured":"Resnick J, Vernier RL (1987) Renal cystic disease and renal dysplasia. In: Holliday MA, Barratt TM, Vernler RL (eds) Pediatric nephrology, 2nd edn. Williams and Wilkins, London, pp 371\u2013383","edition":"2nd edn."},{"key":"BF00864387_CR8","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1016\/S0168-8278(86)80073-3","volume":"2","author":"JA Summerfield","year":"1986","unstructured":"Summerfield JA, Nagafuchi Y, Sherlock S, Cadafalch J, Scheuer PJ (1986) Hepatobiliary fibropolycystic diseases, a clinical and histological review of 51 patients. J Hepatol 2: 141\u2013156","journal-title":"J Hepatol"},{"key":"BF00864387_CR9","first-page":"1124","volume-title":"Pediatric gastrointestinal disease, vol 2","author":"DA Picolli","year":"1991","unstructured":"Picolli DA, Witzleben CL (1991) Disorders of intrahepatic bile ducts. In: Walker WA, Durie PR, Hamilton JR, Walker-Smith, Watkins JB (eds) Pediatric gastrointestinal disease, vol 2. Decker, Philadelphia, pp 1124\u20131140"},{"key":"BF00864387_CR10","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1007\/978-1-4613-1603-9_13","volume-title":"Inheritance of kidney and urinary tract diseases","author":"BS Kaplan","year":"1990","unstructured":"Kaplan BS, Kaplan P (1990) Autosomal recessive polycystic kidney disease. In: Spitzer A, Avner ED (eds) Inheritance of kidney and urinary tract diseases. Kluwer, Dordrecht, pp 265\u2013276"},{"key":"BF00864387_CR11","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1016\/S0168-8278(85)80752-2","volume":"1","author":"VJ Desmet","year":"1985","unstructured":"Desmet VJ (1985) Intrahepatic bileducts under the lens. J Hepatol 1: 545\u2013549","journal-title":"J Hepatol"},{"key":"BF00864387_CR12","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1007\/BF00853593","volume":"1","author":"ED Avner","year":"1987","unstructured":"Avner ED, Studnicki FE, Young MC, Sweeney WE Jr, Piesco NP, Ellis D, Fetterman GH (1987) Congenital murine polycystic disease. I. The ontogeny of tubular cyst formation. Pediatr Nephrol 1: 587\u2013596","journal-title":"Pediatr Nephrol"},{"issue":"Suppl","key":"BF00864387_CR13","first-page":"1","volume":"257","author":"MJ J\u00f8rgensen","year":"1977","unstructured":"J\u00f8rgensen MJ (1977) The ductal plate malformation. Acta Pathol Microbiol Scand A [Suppl] 257: 1\u201388","journal-title":"Acta Pathol Microbiol Scand A"},{"key":"BF00864387_CR14","doi-asserted-by":"crossref","first-page":"7447","DOI":"10.1073\/pnas.89.16.7447","volume":"89","author":"ED Avner","year":"1992","unstructured":"Avner ED, Sweeney WE, Nelson WJ (1992) Abnormal sodium pump distribution during renal tubulogenesis in congenital murine polycystic kidney disease. Proc Natl Acad Sci USA 89: 7447\u20137451","journal-title":"Proc Natl Acad Sci USA"},{"key":"BF00864387_CR15","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1016\/0012-1606(91)90249-3","volume":"146","author":"MA Harding","year":"1991","unstructured":"Harding MA, Chadwick LJ, Gattone VH, Calvet JP (1991) The SGP-2 gene is developmentally regulated in the mouse kidney and abnormally expressed in collecting duct cysts in polycystic kidney disease. Dev Biol 146: 483\u2013490","journal-title":"Dev Biol"},{"key":"BF00864387_CR16","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1007\/978-94-009-0457-6_4","volume-title":"The cystic kidney","author":"ED Avner","year":"1990","unstructured":"Avner ED, McAteer JA, Evan AP (1990) Models of cysts and cystic kidneys. In: Gardner KD, Bernstein J (eds) The cystic kidney. Kluwer, Dordrecht, pp 55\u201398"},{"key":"BF00864387_CR17","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1007\/BF00862593","volume":"2","author":"ED Avner","year":"1988","unstructured":"Avner ED, Sweeney WE Jr, Young MC, Ellis D (1988) Congenital murine polycystic kidney disease. Pediatr Nephrol 2: 210\u2013218","journal-title":"Pediatr Nephrol"},{"key":"BF00864387_CR18","doi-asserted-by":"crossref","first-page":"828","DOI":"10.1016\/S0022-5347(17)47448-9","volume":"134","author":"JL Fry","year":"1985","unstructured":"Fry JL, Koch WE, Jennette JC, Mc Farland MA, Mandel J (1985) A genetically determined murine model of infantile polycystic kidney disease. J Urol 134: 828\u2013833","journal-title":"J Urol"},{"key":"BF00864387_CR19","doi-asserted-by":"crossref","first-page":"1088","DOI":"10.1038\/ki.1987.112","volume":"31","author":"JFS Crocker","year":"1987","unstructured":"Crocker JFS, Blecher SR, Givner ML, McCarthy SC (1987) Folycystic kidney and liver disease and corticosterone changes in the cpk mouse. Kidney Int 31: 1088\u20131091","journal-title":"Kidney Int"},{"key":"BF00864387_CR20","first-page":"119","volume":"71","author":"PC Grimm","year":"1990","unstructured":"Grimm PC, Crocker JFS, Malatjalian DA, Ogborn MR (1990) The microanatomy of the intrahepatic bile duct in polycystic disease: comparison of the cpk mouse and human. J Exp Pathol 71: 119\u2013120","journal-title":"J Exp Pathol"},{"key":"BF00864387_CR21","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1177\/35.1.3794309","volume":"35","author":"L Laitinen","year":"1987","unstructured":"Laitinen L, Virtanen I, Sax\u00e9n L (1987) Changes in the glycosylation pattern during embryonic development of mouse kidney as revealed with lectin conjugates. J Histochem Cytochem 35: 55\u201365","journal-title":"J Histochem Cytochem"},{"key":"BF00864387_CR22","doi-asserted-by":"crossref","first-page":"372","DOI":"10.1007\/BF00862522","volume":"4","author":"ED Avner","year":"1990","unstructured":"Avner ED, Sweeney WE Jr (1990) Polypeptide growth factors in metanephric growth and segmental nephron differentiation. Pediatr Nephrol 4: 372\u2013377","journal-title":"Pediatr Nephrol"},{"key":"BF00864387_CR23","first-page":"52","volume":"59","author":"P Eyken Van","year":"1988","unstructured":"Van Eyken P, Sciot R, Desmet VJ (1988) Intrahepatic bile duct development in the rat: a cytokeratin-immunohistochemical study. Lab Invest 59: 52\u201359","journal-title":"Lab Invest"},{"key":"BF00864387_CR24","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1007\/BF02388120","volume":"13","author":"WE Sweeney Jr","year":"1991","unstructured":"Sweeney WE Jr, Avner ED (1991) Intact organ culture of murine metanephros. J Tissue Cult Methods 13: 163\u2013168","journal-title":"J Tissue Cult Methods"},{"key":"BF00864387_CR25","first-page":"1151","volume":"28","author":"SM Morris","year":"1991","unstructured":"Morris SM, Sweeney WE, Kepka DM, O'Brien WE, Avner ED (1991) Localization of arginine biosynthetic enzymes in renal proximal tubules and abundance of mRNA during development. Pediatr Res 28: 1151\u20131154","journal-title":"Pediatr Res"},{"key":"BF00864387_CR26","first-page":"3.28","volume-title":"Sigmascan manual","author":"CJ Acker","year":"1987","unstructured":"Acker CJ, Mitchel D (1987) Sigmascan manual. Jandel Scientific, Sausolito, California, pp 3.28\u20133.34"},{"key":"BF00864387_CR27","doi-asserted-by":"crossref","first-page":"632","DOI":"10.1016\/S0022-5347(17)38840-7","volume":"142","author":"PW Woodbury","year":"1989","unstructured":"Woodbury PW, Mitchell ME, Scheidler DM, Adams MC, Rink RC, McNulty A (1989) Constant pressure perfusion: a method to derter mine obstruction in the upper urinary tract. J Urol 142: 632\u2013635","journal-title":"J Urol"},{"key":"BF00864387_CR28","doi-asserted-by":"crossref","first-page":"556","DOI":"10.1016\/S0022-5347(17)53911-7","volume":"127","author":"GM Preminger","year":"1982","unstructured":"Preminger GM, Koch WE, Fried FA, Mc Farland E, Murphy ED, Mandell J (1982) Murine congenital polycystic kidney disease: a model for studying development of cystic disease. J Urol 127: 556\u2013560","journal-title":"J Urol"},{"key":"BF00864387_CR29","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1007\/BF01975904","volume":"42","author":"ED Avner","year":"1986","unstructured":"Avner ED, Sweeney WE Jr, Piesco NP, Ellis D (1986) Regression of genetically determined polycystic kidney disease in murine organ culture. Experientia 42: 77\u201380","journal-title":"Experientia"},{"key":"BF00864387_CR30","doi-asserted-by":"crossref","first-page":"960","DOI":"10.1038\/ki.1989.288","volume":"36","author":"ED Avner","year":"1989","unstructured":"Avner ED, Sweeney WE Jr, Ellis D (1989) In vitro modulation of tubular cyst regression in murine polycystic kidney disease. Kidney Int 36: 960\u2013968","journal-title":"Kidney Int"},{"key":"BF00864387_CR31","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1007\/BF00859623","volume":"3","author":"R Verani","year":"1989","unstructured":"Verani R, Walker P, Silva FG (1989) Renal cystic disease of infancy: results of histochemical studies. Pediatr Nephrol 3: 37\u201342","journal-title":"Pediatr Nephrol"},{"key":"BF00864387_CR32","first-page":"363","volume":"62","author":"H Holthofer","year":"1990","unstructured":"Holthofer H, Kumpulainen T, Rapola J (1990) Polycystic disease of the kidney. Evaluation and classification based on nephron segment and cell-type specific markers. Lab Invest 62: 363\u2013369","journal-title":"Lab Invest"},{"key":"BF00864387_CR33","first-page":"670","volume":"81","author":"MJ J\u00f8rgensen","year":"1973","unstructured":"J\u00f8rgensen MJ (1973) A stereological study of intrahepatic bile ducts. Acta Pathol Microbiol Scand A 81: 670\u2013675","journal-title":"Acta Pathol Microbiol Scand A"},{"key":"BF00864387_CR34","first-page":"91","volume":"30","author":"DNS Kerr","year":"1961","unstructured":"Kerr DNS, Harrison CV, Sherlock S, Milnes Walker R (1961) Congenital hepatic fibrosis. Q J Med 30: 91\u2013117","journal-title":"Q J Med"},{"key":"BF00864387_CR35","volume-title":"Maladies des voies biliaires inuauepatiques segmentaires","author":"J Caroli","year":"1964","unstructured":"Caroli J, Corcos V (1964) Maladies des voies biliaires inuauepatiques segmentaires. Masjon and Cie, Paris"},{"key":"BF00864387_CR36","first-page":"257","volume":"2","author":"J Nauta","year":"1991","unstructured":"Nauta J, Sweeney WE, Avner ED (1991) Epithelial hyperplasia and cell polarity abnormalities in murine autosomal recessive polycystic kidney disease (abstract). J Am Soc Nephrol 2: 257","journal-title":"J Am Soc Nephrol"}],"container-title":["Pediatric Nephrology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF00864387.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/BF00864387\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF00864387","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF00864387.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,2,17]],"date-time":"2020-02-17T14:23:04Z","timestamp":1581949384000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/BF00864387"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1993,4]]},"references-count":36,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1993,4]]}},"alternative-id":["BF00864387"],"URL":"https:\/\/doi.org\/10.1007\/bf00864387","relation":{},"ISSN":["0931-041X","1432-198X"],"issn-type":[{"value":"0931-041X","type":"print"},{"value":"1432-198X","type":"electronic"}],"subject":[],"published":{"date-parts":[[1993,4]]}}}