{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,25]],"date-time":"2025-09-25T22:53:27Z","timestamp":1758840807370},"reference-count":39,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[1980,3,1]],"date-time":"1980-03-01T00:00:00Z","timestamp":320716800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Inflammation"],"published-print":{"date-parts":[[1980,3]]},"DOI":"10.1007\/bf00914108","type":"journal-article","created":{"date-parts":[[2004,12,30]],"date-time":"2004-12-30T00:27:14Z","timestamp":1104366434000},"page":"113-123","source":"Crossref","is-referenced-by-count":9,"title":["Inhibition of immune complex-mediated activation of complement"],"prefix":"10.1007","volume":"4","author":[{"given":"Daniel S.","family":"Fletcher","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tsau -yen","family":"Lin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"CR1","doi-asserted-by":"crossref","unstructured":"Agnello, V., D.Koffer, J. W.Eisenberg, R. J.Winchester, and H. G,Kunkel. 1971. Clq precipitins in the sera of patients with systemic lupus erythematosis and other hypocomplementernic states: Characterization of high and low molecular weight types.J. Exp. Med 134:228s.","DOI":"10.1084\/jem.134.3.228"},{"key":"CR2","first-page":"689","volume":"6","author":"R. J. Winchester","year":"1970","unstructured":"Winchester, R. J., V. Agnello, andH. C. Kunkel. 1970. Gamma globulin complexes in synovial fluids of patients with rheumatoid arthritis.Clin. Exp. Immunol. 6:689.","journal-title":"Clin. Exp. Immunol."},{"key":"CR3","doi-asserted-by":"crossref","first-page":"1011","DOI":"10.1016\/0019-2791(71)90489-7","volume":"8","author":"W. Augener","year":"1971","unstructured":"Augener, W., H. M. Grey, N. R. Cooper, andH. J. M\u00fcller-Eberhard. 1971. The reaction of monomeric and aggregated immunoglobulins with Cl.Immunochemistry 8:1011.","journal-title":"Immunochemistry"},{"key":"CR4","first-page":"1","volume-title":"Contempory Topics in Molecular Immunology, Vol. 4","author":"K. B. M. Reid","year":"1975","unstructured":"Reid, K. B. M., andR. R. Porter. 1975. The structure and mechanism of activation of the first component of complement.In Contempory Topics in Molecular Immunology, Vol. 4. F. P. Inman and W. J. Mandy, editors. Plenum Press, New York. 1."},{"key":"CR5","doi-asserted-by":"crossref","first-page":"608","DOI":"10.3181\/00379727-101-25034","volume":"101","author":"L. R. Levy","year":"1959","unstructured":"Levy, L. R., andI. H. Lepow. 1959. Assay and properties of serum inhibitors of C'lesterase.Proc. Soc. Exp. Biol. Med. 101:608.","journal-title":"Proc. Soc. Exp. Biol. Med."},{"key":"CR6","doi-asserted-by":"crossref","first-page":"967","DOI":"10.1016\/0019-2791(75)90260-8","volume":"12","author":"J. D. Conradie","year":"1975","unstructured":"Conradie, J. D., J. E. Volanakis, andR. M. Stroud. 1975. Evidence for a serum inhibitor of Clq.Immunochemistry 12:967.","journal-title":"Immunochemistry"},{"key":"CR7","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1016\/0019-2791(77)90229-4","volume":"14","author":"R. M. Chapuis","year":"1977","unstructured":"Chapuis, R. M., H. Isliker, andS. N. Assimeh. 1977. Studies on the precursor form of the first component of complement-I.Immunochemistry 14:313.","journal-title":"Immunochemistry"},{"key":"CR8","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1042\/bj1570541","volume":"157","author":"I. Gigli","year":"1976","unstructured":"Gigli, I., R. R. Porter, andR. B. Sim. 1976. The unactivated form of the first component of human complement, Cl.Biochem. J. 157:541.","journal-title":"Biochem. J."},{"key":"CR9","first-page":"159","volume-title":"Methods in Immunology","year":"1970","unstructured":"Campbell, D. H., J. S. Garvey, N. E. Cremer, andD. H. Sussdorf, editors. 1970. Methods in Immunology. W. A. Benjamin, Inc. New York. 159."},{"key":"CR10","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1016\/0019-2791(76)90383-9","volume":"13","author":"K. Furuichi","year":"1976","unstructured":"Furuichi, K., M. Kato, T. Nakamura, andJ. Koyama. 1976. Further evidence for preferential production of IgG2 anti-DNP antibody in guinea pigs immunized with DNPEscherichia coli.Immunochemistry 13:455.","journal-title":"Immunochemistry"},{"key":"CR11","first-page":"16","volume-title":"Methods of Immunology and Immunochemistry, Vol. V, Antigen-Antibody Reactions","author":"Z. Ovary","year":"1976","unstructured":"Ovary, Z. 1976. Passive cutaneous anaphalaxis.In Methods of Immunology and Immunochemistry, Vol. V, Antigen-Antibody Reactions In Vivo. C. A. Williams and M. W. Chase, editors. Academic Press, New York. 16."},{"key":"CR12","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1016\/0161-5890(78)90050-0","volume":"15","author":"T.-Y. Lin.","year":"1978","unstructured":"Lin. T.-Y., andD. S. Fletcher. 1978. Interaction of human Clq with insoluble immunoglobulin aggregates.Immunochemistry 15:107.","journal-title":"Immunochemistry"},{"key":"CR13","doi-asserted-by":"crossref","first-page":"4503","DOI":"10.1021\/bi00839a042","volume":"8","author":"D. H. Bing","year":"1969","unstructured":"Bing, D. H. 1969. Nature of the active site of a subunit of the first component of human complement.Biochemistry 8:4503.","journal-title":"Biochemistry"},{"key":"CR14","doi-asserted-by":"crossref","first-page":"4406","DOI":"10.1016\/S0021-9258(18)94333-4","volume":"244","author":"K. Weber","year":"1969","unstructured":"Weber, K., andM. Osborn. 1969. The reliability of molecular weight determinations by dodecyl sulfate-polyacrylamide gel electrophoresis.J. Biol. Chem. 244:4406.","journal-title":"J. Biol. Chem."},{"key":"CR15","doi-asserted-by":"crossref","first-page":"965","DOI":"10.1084\/jem.119.6.965","volume":"119","author":"E. Unanue","year":"1964","unstructured":"Unanue, E., andF. J. Dixon. 1964. Experimental glomerulonephritts IV. Participation of complement in nephrotoxic nephritis.J. Exp. Med. 119:965.","journal-title":"J. Exp. Med."},{"key":"CR16","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/S0021-9258(19)52451-6","volume":"193","author":"O. H. Lowry","year":"1951","unstructured":"Lowry, O. H., N. J. Rosebrough, A. L. Farr, andR. J. Randall. 1951. Protein measurement with the Folin phenol reagent.J. Biol. Chem. 193:265.","journal-title":"J. Biol. Chem."},{"key":"CR17","doi-asserted-by":"crossref","first-page":"820","DOI":"10.4049\/jimmunol.110.3.820","volume":"110","author":"C. Heusser","year":"1973","unstructured":"Heusser, C., M. Boesman, J. H. Nordin, andH. Isliker. 1973. Effect of chemical and enzymatic radioiodination on in vitro human Clq activities.J. Immunol. 110:820.","journal-title":"J. Immunol."},{"key":"CR18","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/S0065-2776(08)60298-9","volume":"16","author":"C. G. Cochrane","year":"1973","unstructured":"Cochrane, C. G., andD. Koffler. 1973. Immune complex disease in experimental animals and man.Adv. Immunol. 16:185.","journal-title":"Adv. Immunol."},{"key":"CR19","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/S0065-2776(08)60299-0","volume":"16","author":"N. J. Zvaifler","year":"1973","unstructured":"Zvaifler, N. J. 1973. The immunopathology of joint inflammation and rheumatoid arthritis.Adv. Immunol. 16:265.","journal-title":"Adv. Immunol."},{"key":"CR20","first-page":"127","volume":"10","author":"J. S. C. Fong","year":"1972","unstructured":"Fong, J. S. C., andR. A. Good. 1972. Suramin-a potent reversible and competitive inhibitor of complement systems.Clin. Exp. Immunol. 10:127.","journal-title":"Clin. Exp. Immunol."},{"key":"CR21","first-page":"509","volume":"34","author":"Y. Takada","year":"1978","unstructured":"Takada, Y., Y. Arimoto, H. Mineda, andA. Takada. 1978. Inhibition of the classical and alternative pathways by amino acids and their derivatives.Immunology 34:509.","journal-title":"Immunology"},{"key":"CR22","first-page":"395","volume":"17","author":"D. R. Schultz","year":"1974","unstructured":"Schultz, D. R., J. E. Volanakis, P. I. Arnold, N. L. Gottlieb, K. Sakai, andR. M. Stroud. 1974. Inactivation of Cl in rheumatoid synovial fluid, purified Cl and Cl esterase, by gold compounds.Clin. Exp. Immunol. 17:395.","journal-title":"Clin. Exp. Immunol."},{"key":"CR23","doi-asserted-by":"crossref","first-page":"466","DOI":"10.4049\/jimmunol.118.2.466","volume":"118","author":"J. M. Andrews","year":"1977","unstructured":"Andrews, J. M., F. S. Rosen, S. J. Silvesberg, M. Corey, E. E. Schneeberger, andD. H. Bing. 1977. Inhibition of $$\\overline {\\operatorname{CLs} } $$ -induced vascular leakage in guinea pigs by substituted benzamidine and pyridinium compounds.J. Immunol. 118:466.","journal-title":"J. Immunol."},{"key":"CR24","doi-asserted-by":"crossref","first-page":"1","DOI":"10.4049\/jimmunol.102.1.1","volume":"102","author":"M. M. Glovsky","year":"1969","unstructured":"Glovsky, M. M., P. A. Ward, E. L. Becker, andN. J. Halbrook. 1969. Role of fumaropimaric acid in guinea pig complement dependent and non-complement dependent biological reactions.J. Immunol. 102:1.","journal-title":"J. Immunol."},{"key":"CR25","first-page":"459","volume":"34","author":"N. C. Hughes-Jones","year":"1978","unstructured":"Hughes-Jones, N. C., andB. Gardner. 1978. The reaction between the complement subcomponent Clq, IgG complexes and polyionic molecules.Immunology 34:459.","journal-title":"Immunology"},{"key":"CR26","doi-asserted-by":"crossref","first-page":"983","DOI":"10.7164\/antibiotics.29.983","volume":"29","author":"K. Takahashi","year":"1976","unstructured":"Takahashi, K., K. Tamoto, andJ. Koyama. 1976. Effects of protease inhibitors of actinomycetes on the first component of human complement.J. Antibiot. 29:983.","journal-title":"J. Antibiot."},{"key":"CR27","doi-asserted-by":"crossref","first-page":"558","DOI":"10.7164\/antibiotics.22.558","volume":"22","author":"T. Aoyagi","year":"1969","unstructured":"Aoyagi, T., S. Miyata, M. Nanbu, F. Kojima, M. Matsuzaki, M. Ishizuka, T. Takeuchi, andH. Umezawa. 1969. Biological activity of leupeptins.J. Antbiol. 22:558.","journal-title":"J. Antbiol."},{"key":"CR28","first-page":"429","volume-title":"Proteases and Biological Control","author":"T. Aoyagi","year":"1975","unstructured":"Aoyagi, T., andH. Umezawa. 1975. Structure and activities of protease inhibitors of microbial origin.In Proteases and Biological Control. E. Reich, D. B. Rifkin, and E. Shaw, editors. Cold Spring Harbor Laboratory, Cold Spring Harbor, New York. 429."},{"key":"CR29","doi-asserted-by":"crossref","first-page":"534","DOI":"10.1126\/science.622552","volume":"199","author":"P. Libby","year":"1978","unstructured":"Libby, P., andA. L. Goldberg. 1978. Leupeptin, a protease inhibitor, decreases protein degradation in normal and diseased muscles.Science 199:534.","journal-title":"Science"},{"key":"CR30","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1016\/0005-2795(73)90247-X","volume":"317","author":"S. S. Asghar","year":"1973","unstructured":"Asghar, S. S., K. W. Pondman, andR. H. Cormane. 1973. Inhibition of $$\\overline {\\operatorname{CL} \\operatorname{r} } $$ , $$\\overline {\\operatorname{CLs} } $$ and generation of $$\\overline {\\operatorname{CLs} } $$ by amidino compounds.Biochim. Biophys. Acta 317:539.","journal-title":"Biochim. Biophys. Acta"},{"key":"CR31","doi-asserted-by":"crossref","first-page":"928","DOI":"10.4049\/jimmunol.114.3.928","volume":"114","author":"N. A. Soter","year":"1975","unstructured":"Soter, N. A., K. F. Austen, andI. Gigli. 1975. Inhibition by epsilon-aminocaproic acid of the activation of the first component of the complement system.J. Immunol. 114:928.","journal-title":"J. Immunol."},{"key":"CR32","first-page":"1","volume":"448","author":"I. M. Nilsson","year":"1966","unstructured":"Nilsson, I. M., I. Andersson, andS. E. Bjorkman. 1966. Epsilon-aminocaproic acid (EACA) as a therapeutic agent based on 5 years' clinical experience,Acta Med. Scand. (Suppl)448:1.","journal-title":"Acta Med. Scand. (Suppl)"},{"key":"CR33","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/0002-9343(63)90162-1","volume":"35","author":"V. H. Donaldson","year":"1963","unstructured":"Donaldson, V. H., andR. R. Evans. 1963. A biochemical abnormality in hereditary angioneurotic edema: Absence of serum inhibitor of Cl-esterase.Am. J. Med.,35:37.","journal-title":"Am. J. Med."},{"key":"CR34","first-page":"163","volume":"2","author":"D. Brackertz","year":"1973","unstructured":"Brackertz, D., andF. Kueppers. 1973. A one years' follow up of treatment of hereditary angioneurotic edema with suramin.Allergol. Immunopathol. 2:163.","journal-title":"Allergol. Immunopathol."},{"key":"CR35","doi-asserted-by":"crossref","first-page":"678","DOI":"10.1111\/j.1476-5381.1973.tb08544.x","volume":"49","author":"V. Eisen","year":"1973","unstructured":"Eisen, V., andC. Loveday, 1973. Effects of suramin on complement, blood clotting, fifrinolysis and kinin formation.Br. J. Pharmacol. 49:678.","journal-title":"Br. J. Pharmacol."},{"key":"CR36","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1042\/bj0470158","volume":"47","author":"E. D. Wills","year":"1950","unstructured":"Wills, E. D., andA. Wormall. 1950. Studies on suramin. 9. The action of the drug on some enzymes.Biochem. J. 47:158.","journal-title":"Biochem. J."},{"key":"CR37","volume-title":"Handbook of Pharmacology","author":"W. C. Cutting","year":"1964","unstructured":"Cutting, W. C. 1964. Handbook of Pharmacology. Appleton-Century-Crofts, New York."},{"key":"CR38","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1007\/BF00495555","volume":"304","author":"C. H. C. M. Buys","year":"1978","unstructured":"Buys, C. H. C. M., J. M. W. Bouma, M. Gruber, andE. Wisse. 1978. Induction of lysosomal storage by suramin.Arch. Pharmacol. 304:183.","journal-title":"Arch. Pharmacol."},{"key":"CR39","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1084\/jem.147.2.369","volume":"147","author":"G. F. Schreiner","year":"1978","unstructured":"Schreiner, G. F., R. S. Cotran, V. Pardo, andE. R. Unanue. 1978. A mononuclear cell component in experimental immunological glomerulonephritis.J. Exp. Med. 147:369.","journal-title":"J. Exp. Med."}],"container-title":["Inflammation"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF00914108.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/BF00914108\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF00914108","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,1]],"date-time":"2023-05-01T06:26:18Z","timestamp":1682922378000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/BF00914108"}},"subtitle":["Effects of agents modulating activation of, and the activated Cl complex"],"short-title":[],"issued":{"date-parts":[[1980,3]]},"references-count":39,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1980,3]]}},"alternative-id":["BF00914108"],"URL":"https:\/\/doi.org\/10.1007\/bf00914108","relation":{},"ISSN":["0360-3997","1573-2576"],"issn-type":[{"value":"0360-3997","type":"print"},{"value":"1573-2576","type":"electronic"}],"subject":[],"published":{"date-parts":[[1980,3]]}}}