{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T14:49:56Z","timestamp":1761058196636},"reference-count":42,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[1987,3,1]],"date-time":"1987-03-01T00:00:00Z","timestamp":541555200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Inflammation"],"published-print":{"date-parts":[[1987,3]]},"DOI":"10.1007\/bf00917769","type":"journal-article","created":{"date-parts":[[2005,1,1]],"date-time":"2005-01-01T04:22:33Z","timestamp":1104553353000},"page":"23-37","source":"Crossref","is-referenced-by-count":10,"title":["Stimulated release of neutral proteinases elastase and cathepsin G from inflammatory rat polymorphonuclear leukocytes"],"prefix":"10.1007","volume":"11","author":[{"given":"M. A.","family":"Bray","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"McKearn-Smith","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.","family":"Metz-Virca","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. L.","family":"Bodmer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G. D.","family":"Virca","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"CR1","volume-title":"The Neutrophil: Function and Clinical Disorders","author":"S. J. Klebanoff","year":"1978","unstructured":"Klebanoff, S. J., andR. A. Clark. 1978. The Neutrophil: Function and Clinical Disorders. North Holland, Amsterdam."},{"key":"CR2","first-page":"387","volume":"2","author":"S. T. Hoffstein","year":"1980","unstructured":"Hoffstein, S. T. 1980. Intra-and extracellular secretion from polymorphonuclear leukocytes. The cell biology of inflammation.Handb. Inflamm. 2:387?430.","journal-title":"Handb. Inflamm."},{"key":"CR3","first-page":"597","volume":"46","author":"E. G. Calamai","year":"1982","unstructured":"Calamai, E. G., andJ. K. Spitznagel. 1982. Characterization of rat polymorphonuclear leukocyte subcellular granules.Lab. Invest. 46:597?604.","journal-title":"Lab. Invest."},{"key":"CR4","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1007\/BF00916242","volume":"6","author":"J. Varani","year":"1982","unstructured":"Varani, J., D. Ward, andK. J. Johnson. 1982. Nonspecific protease and elastase activities in rat leukocytes.Inflammation 6:177?187.","journal-title":"Inflammation"},{"key":"CR5","first-page":"371","volume":"5","author":"A. J. Lewis","year":"1985","unstructured":"Lewis, A. J., R. P. Carlson, andJ. Chang. 1985. Experimental models of inflammation. The pharmacology of inflammation.Handb. Inflamm. 5:371?397.","journal-title":"Handb. Inflamm."},{"key":"CR6","first-page":"17","volume-title":"Proteinases in Tumor Invasion","author":"A. Baici","year":"1980","unstructured":"Baici, A. 1980. Structure and breakdown of proteoglycans, collagen and elastin.In Proteinases in Tumor Invasion. P. St\u00e4uli, A. J. Barrett, and A. Baici, editors. Raven Press, New York. 17?48."},{"key":"CR7","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1007\/BF00541264","volume":"2","author":"A. Baici","year":"1982","unstructured":"Baici, A., P. Salgam, G. Cohen, K. Fehr, andA. B\u00f6ni. 1982. Action of collagenase and elastase from human polymorphonuclear leukocytes on human articular cartilage.Rheumatol. Int. 2:11?16.","journal-title":"Rheumatol. Int."},{"key":"CR8","doi-asserted-by":"crossref","first-page":"S2","DOI":"10.1164\/arrd.1983.127.1.2","volume":"127","author":"A. B. Cohen","year":"1983","unstructured":"Cohen, A. B. 1983. Proteases and antiproteases in the lung.Am. Rev. Respir. Dis. (Suppl.) 127:S2-S58.","journal-title":"Am. Rev. Respir. Dis. (Suppl.)"},{"key":"CR9","first-page":"195","volume-title":"Textbook of Rheumatology","author":"A. J. Barrett","year":"1981","unstructured":"Barrett, A. J., andJ. Saklatvala. 1981. Proteinases in joint disease.In Textbook of Rheumatology. W. N. Kelley, E. D. Harris, Jr., S. Ruddy, and C. B. Sledge, editors. W. B. Saunders, Philadelphia. 195?209."},{"key":"CR10","doi-asserted-by":"crossref","first-page":"1154","DOI":"10.1084\/jem.143.5.1154","volume":"143","author":"H. J. Showell","year":"1976","unstructured":"Showell, H. J., R. J. Freer, S. H. Zigmond, E. Schiffmann, S. Aswanikumar, B. Corcoran, andE. L. Becker. 1976. The structure-activity relations of synthetic peptides as chemotactic factors and inducers of lysosomal enzyme secretion for neutrophils.J. Exp. Med. 143:1154?1169.","journal-title":"J. Exp. Med."},{"key":"CR11","doi-asserted-by":"crossref","first-page":"11461","DOI":"10.1016\/S0021-9258(17)39051-8","volume":"260","author":"L. A. Sklar","year":"1985","unstructured":"Sklar, L. A., P. A. Hyslop, Z. G. Oades, G. M. Omann, A. J. Jesaitis, R. G. Painter, andC. G. Cochrane. 1985. Signal transduction and ligand-receptor dynamics in the human neutrophil.J. Biol. Chem. 260:11461?11467.","journal-title":"J. Biol. Chem."},{"key":"CR12","doi-asserted-by":"crossref","first-page":"2916","DOI":"10.1073\/pnas.70.10.2916","volume":"70","author":"I. Goldstein","year":"1973","unstructured":"Goldstein, I., S. Hoffstein, J. Gallin, andG. Wiessmann. 1973. Mechanisms of lysosomal enzyme release from human leukocytes: Microtubule assembly and membrane fusion induced by a component of complement.Proc. Natl. Acad. Sci. U.S.A. 70:2916?2920.","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"CR13","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1093\/oxfordjournals.bmb.a071828","volume":"39","author":"M. A. Bray","year":"1983","unstructured":"Bray, M. A. 1983. Pharmacology and pathophysiology of leukotriene B4.Br. Med. Bull. 39:249?254.","journal-title":"Br. Med. Bull."},{"key":"CR14","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1016\/0014-5793(81)81233-1","volume":"136","author":"S. J. Feinmark","year":"1981","unstructured":"Feinmark, S. J., J. A. Lindgren, H. E. Claesson, C. Malmsten, andB. Samuelsson. 1981. Stimulation of human leukocyte degranulation by leukotriene B4 and its w-oxidized metabolites.FEBS Lett. 136:141?144.","journal-title":"FEBS Lett."},{"key":"CR15","doi-asserted-by":"crossref","first-page":"1250","DOI":"10.4049\/jimmunol.127.3.1250","volume":"127","author":"J. O. Shaw","year":"1981","unstructured":"Shaw, J. O., R. N. Pinckard, K. S. Ferrigni, L. M. McManus, andD. J. Hanahan. 1981. Activation of human neutrophils with 1-O-hexadecyl\/octadecyl-2-acetyl-sn-glyceryl-3-phosphorylcholine (platelet activating factor).J. Immunol. 127:1250?1255.","journal-title":"J. Immunol."},{"key":"CR16","doi-asserted-by":"crossref","first-page":"811","DOI":"10.4049\/jimmunol.128.2.811","volume":"128","author":"H. J. Showell","year":"1982","unstructured":"Showell, H. J., P. H. Naccache, P. Borgeat, S. Picard, P. Vallerand, E. L. Becker, andR. I. Sha'afi. 1982. Characterization of the secretory activity of leukotriene B4 toward rabbit neutrophils.J. Immunol. 128:811?816.","journal-title":"J. Immunol."},{"key":"CR17","doi-asserted-by":"crossref","first-page":"844","DOI":"10.1073\/pnas.70.3.844","volume":"70","author":"R. B. Zurier","year":"1973","unstructured":"Zurier, R. B., S. Hoffstein, andG. Weissmann. 1973. Cytochalasin B: Effect on lysosomal enzyme release from human leukocytes.Proc. Natl. Acad. Sci. U.S.A. 70:844?848.","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"CR18","doi-asserted-by":"crossref","first-page":"1182","DOI":"10.4049\/jimmunol.109.6.1182","volume":"109","author":"P. M. Henson","year":"1972","unstructured":"Henson, P. M., H. B. Johnson, andH. L. Spiegelberg. 1972. The release of granule enzymes from human neutrophils stimulated by aggregated immunoglobulins of different classes and subclasses.J. Immunol. 109:1182?1192.","journal-title":"J. Immunol."},{"key":"CR19","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1128\/IAI.13.1.146-151.1976","volume":"13","author":"R. D. Estensen","year":"1976","unstructured":"Estensen, R. D., M. E. Reusch, M. L. Epstein, andH. R. Hill. 1976. Role of Ca2+ and Mg2+ in some human neutrophil functions as indicated by ionophore A23187.Infect. Immun. 13:45?151.","journal-title":"Infect. Immun."},{"key":"CR20","doi-asserted-by":"crossref","first-page":"769","DOI":"10.1083\/jcb.78.3.769","volume":"78","author":"S. Hoffstein","year":"1978","unstructured":"Hoffstein, S., andG. Weissmann. 1978, Microfilaments and microtubules in calcium ionophore-induced secretion of lysosomal enzymes from human polymorphonuclear leukocytes.J. Cell. Biol. 78:769?781.","journal-title":"J. Cell. Biol."},{"key":"CR21","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1038\/248347a0","volume":"248","author":"R. D. Estensen","year":"1974","unstructured":"Estensen, R. D., J. G. White, andB. Holmes. 1974. Specific degranulation of human polymorphonuclear leukocytes.Nature 248:347?348.","journal-title":"Nature"},{"key":"CR22","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/j.1432-1033.1984.tb08423.x","volume":"144","author":"G. D. Virca","year":"1984","unstructured":"Virca, G. D., G. Metz, andH. P. Schnebli. 1984. Similarities between human and rat leukocyte elastase and cathepsin G.Eur. J. Biochem. 144:1?9.","journal-title":"Eur. J. Biochem."},{"key":"CR23","doi-asserted-by":"crossref","first-page":"5471","DOI":"10.1016\/S0021-9258(19)83801-2","volume":"257","author":"L. A. Sklar","year":"1982","unstructured":"Sklar, L. A., V. M. McNeil, A. J. Jesaitis, R. G. Painter, andC. G. Cochrane. 1982. A continuous, spectroscopic analysis of the kinetics of elastase secretion by neutrophils.J. Biol. Chem. 257:5471?5475.","journal-title":"J. Biol. Chem."},{"key":"CR24","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1016\/0024-3205(73)90053-2","volume":"13","author":"A. J. Anderson","year":"1973","unstructured":"Anderson, A. J., andC. Irwin. 1973. Some properties of neutral acting proteases and other degradative enzymes in rat leukocytes.Life Sci. 13:601?612.","journal-title":"Life Sci."},{"key":"CR25","first-page":"117","volume":"5","author":"M. Baggiolini","year":"1985","unstructured":"Baggiolini, M. 1985. Phagocyte activation and its modulation by drugs. The pharmacology of inflammation.Handb. Inflamm. 5:117?139.","journal-title":"Handb. Inflamm."},{"key":"CR26","doi-asserted-by":"crossref","first-page":"1290","DOI":"10.1016\/0006-291X(81)91587-4","volume":"101","author":"J. T. O'Flaherty","year":"1981","unstructured":"O'Flaherty, J. T., R. L. Wykle, C. E. McCall, T. B. Shewmake, C. J. Lees, andM. Thomas 1981. Desensitisation of the human neutrophil degranulation response: Studies with 5, 12-dihydroxy-6,8,10,14-eicosatetraenoic acid.Biochem. Biophys. Res. Commun. 101:1290?1296.","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"CR27","first-page":"65","volume":"50","author":"R. M. J. Palmer","year":"1983","unstructured":"Palmer, R. M. J., andJ. A. Salmon 1983. Release of leukotriene B4 from human neutrophils and its relationship to degranulation induced by N-formyl-methionyl-leucyl-phenylalanine, serum-treated zymosan, and the ionophore A23187.Immunology 50:65?73.","journal-title":"Immunology"},{"key":"CR28","doi-asserted-by":"crossref","first-page":"2047","DOI":"10.4049\/jimmunol.112.6.2047","volume":"112","author":"E. L. Becker","year":"1974","unstructured":"Becker, E. L., H. J. Showell, P. M. Henson, andL. S. Hsu 1974. The ability of chemotactic factors to induce lysosomal enzyme release. 1. The characteristics of the release, the importance of surfaces, and the relation of enzyme release to chemotactic responsiveness.J. Immunol. 112:2047?2054.","journal-title":"J. Immunol."},{"key":"CR29","doi-asserted-by":"crossref","first-page":"855","DOI":"10.4049\/jimmunol.124.2.855","volume":"124","author":"B. J. Bentwood","year":"1980","unstructured":"Bentwood, B. J., andP. M. Henson. 1980. The sequential release of granule constituents from human neutrophils.J. Immunol. 124: 855?862.","journal-title":"J. Immunol."},{"key":"CR30","first-page":"273","volume":"87","author":"D. G. Wright","year":"1977","unstructured":"Wright, D. G., D. A. Bralove, andJ. I. Gallin. 1977. The differential mobilisation of human neutrophil granules. Effects of phorbol myristate acetate and ionophore A23187.Am. J. Palhol. 87:273?281.","journal-title":"Am. J. Palhol."},{"key":"CR31","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1007\/BF00921005","volume":"2","author":"E. C. Yurewicz","year":"1977","unstructured":"Yurewicz, E. C., andM. Zimmerman. 1977. Cytochalasin B-dependent release of azurophil granule enzymes from human polymorphonuclear leukocytes.Inflammation 2:259?264.","journal-title":"Inflammation"},{"key":"CR32","doi-asserted-by":"crossref","first-page":"737","DOI":"10.1177\/31.6.6404983","volume":"31","author":"W. R. Abrams","year":"1983","unstructured":"Abrams, W. R., L. W. Diamond, andA. B. Kane. 1983. A flow cytometric assay of neutrophil degranulation.J. Histochem. Cytochem. 31:737?744.","journal-title":"J. Histochem. Cytochem."},{"key":"CR33","first-page":"813","volume":"84","author":"C. E. Blackwood","year":"1974","unstructured":"Blackwood, C. E., J. E. Moret, S. Keller, J. A. Fierer, andI. Mandl. 1974. Alphai- antitrypsin concentration in serum of laboratory animals. Changes following proteolytic enzyme injection.J. Lab. Clin. Med. 84:813?822.","journal-title":"J. Lab. Clin. Med."},{"key":"CR34","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1016\/0090-1229(74)90034-8","volume":"2","author":"D. Hawkins","year":"1974","unstructured":"Hawkins, D. 1974. Neutrophilic leukocytes in immunologic reactions in vitro. III Pharmacologic modulation of lysosomal constituent release.Clin. Immunol. Immunopathol. 2:141?152.","journal-title":"Clin. Immunol. Immunopathol."},{"key":"CR35","doi-asserted-by":"crossref","first-page":"781","DOI":"10.1083\/jcb.68.3.781","volume":"68","author":"S. Hoffstein","year":"1976","unstructured":"Hoffstein. S., R. Soberman, I. Goldstein, andG. Weissmann. 1976. Concanavalin A induces microtubule assembly and specific granule discharge in human polymorphonuclear leukocytes.J. Cell. Biol. 68:781?787.","journal-title":"J. Cell. Biol."},{"key":"CR36","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1007\/BF00916046","volume":"4","author":"R. J. Smith","year":"1980","unstructured":"Smith, R. J., andS. S. Iden. 1980. Properties of concanavalin A-elicited granule exocytosis from human polymorphonuclear neutrophils.Inflammation 4:343?358.","journal-title":"Inflammation"},{"key":"CR37","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1016\/0090-1229(74)90006-3","volume":"3","author":"S. Hoffstem","year":"1974","unstructured":"Hoffstem, S., R. B. Zurier, andG. Weissmann. 1974. Mechanisms of lysosomal enzyme release from human leukocytes. III Quantitative morphologic evidence for an effect of cyclic nucleotides and colchicine on degranulation.Clin. Immunol. Immunopathol. 3:201?217.","journal-title":"Clin. Immunol. Immunopathol."},{"key":"CR38","doi-asserted-by":"crossref","first-page":"370","DOI":"10.1007\/BF01986496","volume":"3","author":"G. Weissmann","year":"1973","unstructured":"Weissmann, G., R. B. Zurier, andS. Hoffstein. 1973. Leukocytes as secretory organs in inflammation.Agents Actions 3:370?379.","journal-title":"Agents Actions"},{"key":"CR39","doi-asserted-by":"crossref","first-page":"572","DOI":"10.4049\/jimmunol.123.2.572","volume":"123","author":"N. M. Hadler","year":"1979","unstructured":"Hadler, N. M., J. K. Spitznagel, andR. J. Quinet. 1979. Lysosomal enzymes in inflammatory synovial effussions.J. Immunol. 123:572?577.","journal-title":"J. Immunol."},{"key":"CR40","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1016\/0005-2744(80)90020-0","volume":"615","author":"J. Saklatvala","year":"1980","unstructured":"Saklatvala, J., andA. J. Barrett. 1980. Identification of proteinases in rheumatoid synovium. Detection of leukocyte elastase, cathepsin G, and another serine proteinase.Biochim. Biophys. Acta 615:167?177.","journal-title":"Biochim. Biophys. Acta"},{"key":"CR41","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1007\/978-1-4615-9355-3_29","volume-title":"Proteases","author":"G. D. Virca","year":"1984","unstructured":"Virca, G. D., R. K. Mallya, M. B. Pepys, andH. P. Schnebli. 1984. Quantitaton of human leukocyte elastase, cathepsin G, ?2-macroglobulin and ?1-proteinase inhibitor in osteoarthrosis and rheumatoid arthritis synovial fluids.In Proteases. W. H. Horl and A. Heidland, editors. Plenum Publishing, New York, 345?353."},{"issue":"Suppl. No. 146","key":"CR42","first-page":"217","volume":"69","author":"D. S. Postma","year":"1986","unstructured":"Postma, D. S., B. Folkers, H. J. Sluiter, andH. F. Kauffman. 1986. Discrepancies in release of elastase from human peripheral polymorphonuclear leukocytes.Eur. J. Resp. Dis. (Suppl. No. 146)69:217?224.","journal-title":"Eur. J. Resp. Dis."}],"container-title":["Inflammation"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF00917769.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/BF00917769\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF00917769","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,1]],"date-time":"2023-05-01T07:57:53Z","timestamp":1682927873000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/BF00917769"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1987,3]]},"references-count":42,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1987,3]]}},"alternative-id":["BF00917769"],"URL":"https:\/\/doi.org\/10.1007\/bf00917769","relation":{},"ISSN":["0360-3997","1573-2576"],"issn-type":[{"value":"0360-3997","type":"print"},{"value":"1573-2576","type":"electronic"}],"subject":[],"published":{"date-parts":[[1987,3]]}}}