{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,19]],"date-time":"2025-09-19T10:45:10Z","timestamp":1758278710540},"reference-count":54,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[1977,12,1]],"date-time":"1977-12-01T00:00:00Z","timestamp":249782400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Inflammation"],"published-print":{"date-parts":[[1977,12]]},"DOI":"10.1007\/bf00921011","type":"journal-article","created":{"date-parts":[[2005,1,1]],"date-time":"2005-01-01T08:30:29Z","timestamp":1104568229000},"page":"319-333","source":"Crossref","is-referenced-by-count":16,"title":["Role of granulocytes in immune complex-induced tissue injuries"],"prefix":"10.1007","volume":"2","author":[{"given":"Charles G.","family":"Cochrane","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"CR1","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1084\/jem.94.4.347","volume":"94","author":"C.A. Stetson","year":"1951","unstructured":"Stetson, C.A. 1951. Similarities in the mechanisms determining the Arthus and Schwartzman phenomenon.J. Exp. Med. 94:347.","journal-title":"J. Exp. Med."},{"key":"CR2","first-page":"268","volume":"36","author":"J.H. Humphrey","year":"1955","unstructured":"Humphrey, J.H. 1955. The mechanism of the Arthus reaction. I. The role of polymorphonuclear leukocytes and other factors in reversed passive Arthus reactions in rabbits.Br. J. Exp. Pathol. 36:268.","journal-title":"Br. J. Exp. Pathol."},{"key":"CR3","first-page":"283","volume":"36","author":"J.H. Humphrey","year":"1955","unstructured":"Humphrey, J.H. 1955. The mechanism of the Arthus reaction. II. The role of polymorphonuclear leukocytes and platelets in reversed passive Arthus reactions in the guinea-pig.Br. J. Exp. Pathol. 36:283.","journal-title":"Br. J. Exp. Pathol."},{"key":"CR4","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1084\/jem.110.3.481","volume":"110","author":"C.G. Cochrane","year":"1959","unstructured":"Cochrane, C.G., W.O. Weigle, andF.J. Dixon. 1959. The role of polymorphonuclear leukocytes in the initiation and cessation of the Arthus vasculitis.J. Exp. Med. 110:481.","journal-title":"J. Exp. Med."},{"key":"CR5","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1084\/jem.122.1.83","volume":"122","author":"W.T. Kniker","year":"1965","unstructured":"Kniker, W.T., andC.G. Cochrane. 1965. Pathogenetic factors in vascular lesions of experimental serum sickness.J. Exp. Med. 122:83.","journal-title":"J. Exp. Med."},{"key":"CR6","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1084\/jem.122.1.99","volume":"122","author":"C.G. Cochrane","year":"1965","unstructured":"Cochrane, C.G., E.R. Unanue, andF.J. Dixon. 1965. A role of polymorphonuclear leukocytes and complement in nephrotoxic nephritis.J. Exp. Med. 122:99.","journal-title":"J. Exp. Med."},{"key":"CR7","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1152\/physrev.1954.34.3.529","volume":"34","author":"H. Harris","year":"1954","unstructured":"Harris, H. 1954. Role of chemotaxis in inflammation.Physiol. Rev. 34:529.","journal-title":"Physiol. Rev."},{"key":"CR8","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1016\/0014-4800(63)90019-4","volume":"2","author":"I.K. Buckley","year":"1963","unstructured":"Buckley, I.K. 1963. Delayed secondary damage and leukocyte chemotaxis following focal aseptic heat injuryin vivo.Exp. Molec. Pathol. 2:402.","journal-title":"Exp. Molec. Pathol."},{"key":"CR9","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1002\/path.1700820218","volume":"82","author":"J.V. Hurley","year":"1962","unstructured":"Hurley, J.V., andW.G. Spector. 1962. Delayed leukocyte emigration after intradermal injections and thermal injury.J. Pathol. Bacteriol. 82:403.","journal-title":"J. Pathol. Bacteriol."},{"key":"CR10","doi-asserted-by":"crossref","first-page":"918","DOI":"10.1111\/j.1749-6632.1964.tb52558.x","volume":"116","author":"J.V. Hurley","year":"1964","unstructured":"Hurley, J.V. 1964. Substances promoting leukocyte emigration.In The Acute Inflammatory Process.N. Y. Acad. Sci. 116:918.","journal-title":"N. Y. Acad. Sci."},{"key":"CR11","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1084\/jem.121.2.215","volume":"121","author":"P.A. Ward","year":"1965","unstructured":"Ward, P.A., andC.G. Cochrane. 1965. Bound complement and immunologic injury of blood vessels.J. Exp. Med. 121:215.","journal-title":"J. Exp. Med."},{"key":"CR12","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1084\/jem.122.1.83","volume":"122","author":"W.T. Kniker","year":"1965","unstructured":"Kniker, W.T., andC.G. Cochrane. 1965. Pathogenic factors in vascular lesions of experimental serum sickness.J. Exp. Med. 122:83.","journal-title":"J. Exp. Med."},{"key":"CR13","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1172\/JCI106796","volume":"51","author":"C.V. Shazo De","year":"1972","unstructured":"De Shazo, C.V., P.M. Henson, andC.G. Cochrane. 1972. Acute immunologic arthritis in rabbits.J. Clin. Invest. 51:50.","journal-title":"J. Clin. Invest."},{"key":"CR14","doi-asserted-by":"crossref","first-page":"965","DOI":"10.1084\/jem.117.6.965","volume":"117","author":"K.J. Block","year":"1963","unstructured":"Block, K.J., F.M. Kourilsku, Z. Ovary, andB. Benacerraf 1963. Properties of guinea-pig 7S antibody.III. Identification of antibodies involved in complement fixation and hemolysis.J. exp. Med. 117:965.","journal-title":"J. exp. Med."},{"key":"CR15","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1084\/jem.115.3.453","volume":"115","author":"S. Boyden","year":"1962","unstructured":"Boyden, S. 1962. The chemotactic effect of mixtures of antibody and antigen on polymorphonuclear leukocytes.J. Exp. Med. 115:463.","journal-title":"J. Exp. Med."},{"key":"CR16","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1084\/jem.122.2.327","volume":"122","author":"P.A. Ward","year":"1965","unstructured":"Ward, P.A., C.G. Cochrane, andH.J. M\u00fcller-Eberhard. 1965. The role of serum complement in chemotaxis of leukocytes in vitro.J. Exp. Med. 122:327.","journal-title":"J. Exp. Med."},{"key":"CR17","first-page":"141","volume":"11","author":"P.A. Ward","year":"1966","unstructured":"Ward, P.A., C.G. Cochrane, andH.J. M\u00fcller-Eberhard. 1966. Further studies on the chemotactic factor of complement and its formationin vivo.Immunology 11:141.","journal-title":"Immunology"},{"key":"CR18","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1084\/jem.126.2.189","volume":"126","author":"P.A. Ward","year":"1967","unstructured":"Ward, P.A. 1967. A plasmin split fragment of C?3? as a new chemotactic factor.J. Exp. Med. 126:189.","journal-title":"J. Exp. Med."},{"key":"CR19","doi-asserted-by":"crossref","first-page":"1109","DOI":"10.1084\/jem.129.5.1109","volume":"129","author":"V.A. Bokisch","year":"1969","unstructured":"Bokisch, V.A., H.J. M\u00fcller-Eberhard, andC.G. Cochrane. 1969. Isolation of a fragment (C3a) of the third component of human complement containing anaphylatoxin and chemotactic activity and description of an anaphylatoxin inactivator of human serum.J. Exp. Med. 129:1109.","journal-title":"J. Exp. Med."},{"key":"CR20","doi-asserted-by":"crossref","first-page":"93","DOI":"10.4049\/jimmunol.102.1.93","volume":"102","author":"P.A. Ward","year":"1969","unstructured":"Ward, P.A., andL.J. Newman. 1969. A neutrophil chemotactic factor from C?5?.J. Immunol. 102:93.","journal-title":"J. Immunol."},{"key":"CR21","doi-asserted-by":"crossref","first-page":"813","DOI":"10.4049\/jimmunol.101.4.813.b","volume":"101","author":"H.S. Shin","year":"1968","unstructured":"Shin, H.S., R.J. Pickering, M.M. Mayer, andC.T. Cook. 1968. Guinea pig C?5?.Immunol. 101:813.","journal-title":"Immunol."},{"key":"CR22","first-page":"434","volume":"29","author":"S.B. Taubman","year":"1970","unstructured":"Taubman, S.B., P.R. Goldschmidt, andI.H. Lepow. 1970. Effects of lysosomal enzymes from human leukocytes on human complement components.Fed. Proc. 29:434.","journal-title":"Fed. Proc."},{"key":"CR23","doi-asserted-by":"crossref","first-page":"535","DOI":"10.4049\/jimmunol.104.3.535","volume":"194","author":"P.A. Ward","year":"1970","unstructured":"Ward, P.A., andH.J. Hill. 1970. C5 chemotactic fragments produced by an enzyme in lysozyme granules of neutrophils.J. Immunol. 194:535.","journal-title":"J. Immunol."},{"key":"CR24","doi-asserted-by":"crossref","first-page":"1414","DOI":"10.4049\/jimmunol.108.5.1414","volume":"108","author":"V. Shazo De","year":"1972","unstructured":"De Shazo, V., M. McGrade, P.M. Henson, andC.G. Cochrane. 1972. The effect of complement depletion on neutrophil migration in acute immunologic nephritis.J. Immunol. 108:1414.","journal-title":"J. Immunol."},{"key":"CR25","doi-asserted-by":"crossref","first-page":"733","DOI":"10.1084\/jem.124.4.733","volume":"124","author":"C.G. Cochrane","year":"1966","unstructured":"Cochrane, C.G., andB.S. Aikin. 1966. Polymorphonuclear leukocytes in immunologic reactions: The destruction of vascular basement membranein vivo andin vitro.J. Exp. Med. 124:733.","journal-title":"J. Exp. Med."},{"key":"CR26","first-page":"744","volume":"26","author":"D. Hawkins","year":"1967","unstructured":"Hawkins, D. 1967. Basement membrane material excreted during acute immunologic renal injury.Fed. Proc. 26:744.","journal-title":"Fed. Proc."},{"key":"CR27","doi-asserted-by":"crossref","first-page":"702","DOI":"10.1126\/science.161.3842.702","volume":"161","author":"A. Janoff","year":"1968","unstructured":"Janoff, A., andJ. Zeligs. 1968. Vascular injury and lysis of basement membranein vitro by neutral protease of human leukocytes.Science 161:702.","journal-title":"Science"},{"key":"CR28","doi-asserted-by":"crossref","first-page":"1483","DOI":"10.1126\/science.159.3822.1483","volume":"159","author":"G.S. Lazarus","year":"1968","unstructured":"Lazarus, G.S., R.S. Brown, J.R. Daniels, andM.M. Fullmer. 1968. Human granulocyte collagenase.Science 159:1483.","journal-title":"Science"},{"key":"CR29","doi-asserted-by":"crossref","first-page":"1137","DOI":"10.1084\/jem.128.5.1137","volume":"128","author":"A. Janoff","year":"1968","unstructured":"Janoff, A., andJ. Scherer. 1968. Mediators of inflammation in leukocyte lysosomes. IX. Elastinolytic activity in granules of human polymorphonuclear leukocytes.J. Exp. Med. 128:1137.","journal-title":"J. Exp. Med."},{"key":"CR30","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1111\/j.1749-6632.1968.tb20312.x","volume":"146","author":"M.I. Barnhart","year":"1968","unstructured":"Barnhart, M.I., C. Quintana, H.L. Lenon, G.B. Bluhm, andJ.M. Riddle. 1968. Proteases in inflammation.Ann. N. Y. Acad. Sci. 146:527.","journal-title":"Ann. N. Y. Acad. Sci."},{"key":"CR31","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1055\/s-0038-1651184","volume":"19","author":"J. Prokopowicz","year":"1968","unstructured":"Prokopowicz, J. 1968. Distribution of fibrinolytic and proteolytic enzymes in subcellular fractions of human granulocytes.Thromb. Diath. Haemorrh. 19:84.","journal-title":"Thromb. Diath. Haemorrh."},{"key":"CR32","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/0005-2795(68)90262-6","volume":"154","author":"J. Prokopowicz","year":"1968","unstructured":"Prokopowicz, J. 1968. Purification of plasminogen from human granulocytes using DEAE-Sephadex column chromatography.Biochim. Biophys. Acta 154:91.","journal-title":"Biochim. Biophys. Acta"},{"key":"CR33","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1172\/JCI104051","volume":"39","author":"M. Ziff","year":"1960","unstructured":"Ziff, M., H.S. Gribetz, andJ. Lospalluto. 1960. Effect of leukocytes and synovial membrane extracts on cartilage mucoprotein.Clin. Invest. 39:405.","journal-title":"Clin. Invest."},{"key":"CR34","doi-asserted-by":"crossref","first-page":"302","DOI":"10.3181\/00379727-135-35040","volume":"135","author":"A. Janoff","year":"1970","unstructured":"Janoff, A., andJ. Blondin. 1970. Degradation of cartilage matrix by a neutral protease fraction of human leukocyte lysosomes.Proc. Soc. Exp. Biol. Med. 135:302.","journal-title":"Proc. Soc. Exp. Biol. Med."},{"key":"CR35","first-page":"784","volume":"29","author":"D.T.P. Davies","year":"1970","unstructured":"Davies, D.T.P., K. Krakauer, andG. Weissmann. 1970. Natural protease of granulucoyte lysosomes: Inhibition and activation.Fed. Proc. 29:784.","journal-title":"Fed. Proc."},{"key":"CR36","first-page":"29a","volume":"43","author":"D.T.P. Davies","year":"1969","unstructured":"Davies, D.T.P., andG. Weissmann. 1969. Hydrolysis of histones at neutral pH by granulocyte lysosomes.J. Cell Biol. 43:29a.","journal-title":"J. Cell Biol."},{"key":"CR37","doi-asserted-by":"crossref","first-page":"812","DOI":"10.1084\/jem.140.3.812","volume":"148","author":"B.V. Wintraub","year":"1974","unstructured":"Wintraub, B.V., E.J. Goetzl, andK.F. Austen. 1974. A neutrophil dependent pathway for the generation of a neutral peptide mediator. Partial characterization and control by ?-1 antitrypsin.J. Exp. Med. 148:812.","journal-title":"J. Exp. Med."},{"key":"CR38","doi-asserted-by":"crossref","first-page":"841","DOI":"10.1084\/jem.122.5.841","volume":"122","author":"A. Janoff","year":"1965","unstructured":"Janoff, A. S. Schaffer J. Scherer, andM.A. Bran. 1965. Mediators of inflammation in leukocyte lysosomes.II. Mechanism of action of lysosomal cationic protein upon vascular permeability in the rat.J. Exp. Med. 122:841.","journal-title":"J. Exp. Med."},{"key":"CR39","doi-asserted-by":"crossref","first-page":"605","DOI":"10.1084\/jem.128.4.605","volume":"128","author":"N.S. Ranadive","year":"1968","unstructured":"Ranadive, N.S., andC.G. Cochrane. 1968. Isolation and characterization of permeability factors from rabbit neutrophils.J. Exp. Med. 128:605.","journal-title":"J. Exp. Med."},{"key":"CR40","doi-asserted-by":"crossref","first-page":"1182","DOI":"10.4049\/jimmunol.109.6.1182","volume":"109","author":"P.M. Henson","year":"1972","unstructured":"Henson, P.M., H.B. Johnson, andH.L. Spiegelberg. 1972. The release of granule enzymes from human neutrophils stimulated by aggregated immnnoglobulins of different classes and subclasses.J. Immunol. 109:1182.","journal-title":"J. Immunol."},{"key":"CR41","doi-asserted-by":"crossref","first-page":"1583","DOI":"10.4049\/jimmunol.113.5.1583","volume":"113","author":"I.M. Goldstein","year":"1974","unstructured":"Goldstein, I.M., andG. Weissmann. 1974. Generation of C5-derived lysosomal enzyme-releasing activity (C5a) by lysates of leukocyte lysosomes.J. Immunol. 113:1583.","journal-title":"J. Immunol."},{"key":"CR42","doi-asserted-by":"crossref","unstructured":"Henson, P.M. 1971. Interaction of cells with immune complexes: Adherence, release of constituents, and tissue injury.J. Exp. Med. 134:114s.","DOI":"10.1084\/jem.134.3.114"},{"key":"CR43","doi-asserted-by":"crossref","first-page":"966","DOI":"10.4049\/jimmunol.114.3.966","volume":"114","author":"D.C. Morrison","year":"1975","unstructured":"Morrison, D.C., J.F. Roser, C.G. Cochrane, andP.M. Henson. 1975. The initiation of mast cell degranulation: Activation at the cell membrane.J. Immunol. 114:966.","journal-title":"J. Immunol."},{"key":"CR44","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1172\/JCI105967","volume":"48","author":"R.L. Baehner","year":"1969","unstructured":"Baehner, R.L., M.J. Karnovsky, andM.L. Karnovsky. 1969. Degranulation of leukocytes in chronic granulomatous disease.J. Clin. Invest. 48:187.","journal-title":"J. Clin. Invest."},{"key":"CR45","first-page":"483","volume":"24","author":"D. Hawkins","year":"1971","unstructured":"Hawkins, D., andS. Peeters. 1971. The response of polymorphonuclear leukocytes to immune complexesin vitro.Lab. Invest. 24:483.","journal-title":"Lab. Invest."},{"key":"CR46","doi-asserted-by":"crossref","unstructured":"Weissmann, G., R.B.Zurier, P.J.Spieler, and I.R.Goldstein. 1971. Mechanisms of lysosomal enzyme release from leukocytes exposed to immune complexes and other particles.J. Exp. Med. 134:149s.","DOI":"10.1084\/jem.134.3.149"},{"key":"CR47","doi-asserted-by":"crossref","first-page":"290","DOI":"10.4049\/jimmunol.110.1.290","volume":"110","author":"P.M. Henson","year":"1973","unstructured":"Henson, P.M., andZ.G. Oades 1973. Enhancement of immunologically induced granule exocytosis from neutrophils by cytochalasin B.J. Immunol. 110:290.","journal-title":"J. Immunol."},{"key":"CR48","first-page":"155","volume-title":"Progress in Immunology I","author":"P.M. Henson","year":"1972","unstructured":"Henson, P.M. 1972. Release of biologically active constituents from blood cells and its role in antibody-mediated tissue injury.In Progress in Immunology I, B. Amos, editor. Academic Press, New York. 155."},{"key":"CR49","first-page":"173","volume-title":"Biological Activities of Complement","author":"P.M. Henson","year":"1972","unstructured":"Henson, P.M. 1972. Complement dependent adherence of cells to antigen and antibody: Mechanisms and consequences.In Biological Activities of Complement, D. G. Ingram, editor. S. Karger, Basel. 173?201."},{"key":"CR50","doi-asserted-by":"crossref","first-page":"745","DOI":"10.1084\/jem.130.4.745","volume":"130","author":"D.S. Pearlman","year":"1969","unstructured":"Pearlman, D.S., P.A. Ward, andE.L. Becker. 1969. The requirement of serine esterase function in complement-dependent erythrophagocytosis.J. Exp. Med. 130: 745.","journal-title":"J. Exp. Med."},{"key":"CR51","first-page":"539","volume":"68","author":"G. Weissmann","year":"1972","unstructured":"Weissmann, G., R.B. Zurier, andS. Hoffstein. 1972. Leukocytic proteases and the immunologic release of lysosomal enzymes.Am. J. Pathol. 68:539.","journal-title":"Am. J. Pathol."},{"key":"CR52","first-page":"748","volume":"31","author":"D. Hawkins","year":"1972","unstructured":"Hawkins, D. 1972. Inhibition of neutrophil lysosomal release.Fed. Proc. Abs. 31:748,3002.","journal-title":"Fed. Proc. Abs."},{"key":"CR53","doi-asserted-by":"crossref","first-page":"294","DOI":"10.4049\/jimmunol.110.1.294","volume":"110","author":"D. Hawkins","year":"1973","unstructured":"Hawkins, D. 1973. Neutrophilic leukocytes in immunologic reactionsin vitro: Effect of cytochalasin B.J. Immunol. 110:294.","journal-title":"J. Immunol."},{"key":"CR54","doi-asserted-by":"crossref","first-page":"628","DOI":"10.1056\/NEJM197509252931303","volume":"293","author":"J.T. Curnutte","year":"1975","unstructured":"Curnutte, J.T., R.S. Kipnes, andB.M. Babior. 1975.N. Engl. J. Med. 293:628.","journal-title":"N. Engl. J. Med."}],"container-title":["Inflammation"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF00921011.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/BF00921011\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF00921011","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,17]],"date-time":"2024-01-17T21:19:43Z","timestamp":1705526383000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/BF00921011"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1977,12]]},"references-count":54,"journal-issue":{"issue":"4","published-print":{"date-parts":[[1977,12]]}},"alternative-id":["BF00921011"],"URL":"https:\/\/doi.org\/10.1007\/bf00921011","relation":{},"ISSN":["0360-3997","1573-2576"],"issn-type":[{"value":"0360-3997","type":"print"},{"value":"1573-2576","type":"electronic"}],"subject":[],"published":{"date-parts":[[1977,12]]}}}