{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,12]],"date-time":"2026-06-12T14:17:18Z","timestamp":1781273838974,"version":"3.54.1"},"reference-count":37,"publisher":"Springer Science and Business Media LLC","issue":"10","license":[{"start":{"date-parts":[[1997,10,1]],"date-time":"1997-10-01T00:00:00Z","timestamp":875664000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Graefe's Arch Clin Exp Ophthalmol"],"published-print":{"date-parts":[[1997,10]]},"DOI":"10.1007\/bf00946939","type":"journal-article","created":{"date-parts":[[2005,1,7]],"date-time":"2005-01-07T21:16:40Z","timestamp":1105132600000},"page":"634-638","source":"Crossref","is-referenced-by-count":38,"title":["Inverse correlation between endothelin-1-induced peripheral microvascular vasoconstriction and blood pressure in glaucoma patients"],"prefix":"10.1007","volume":"235","author":[{"given":"Andreas","family":"Gass","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Josef","family":"Flammer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lilly","family":"Linder","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Silvana C.","family":"Romerio","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul","family":"Gasser","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Walter E.","family":"Haefeli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"CR1","doi-asserted-by":"crossref","first-page":"1451","DOI":"10.1016\/0140-6736(93)92932-J","volume":"342","author":"GV Bedarida","year":"1993","unstructured":"Bedarida GV, Kim D, Blaschke TF, Hoffman BB (1993) Venodilation in Raynaud's disease. Lancet 342:1451?1454","journal-title":"Lancet"},{"issue":"suppl 3","key":"CR2","doi-asserted-by":"crossref","first-page":"S96","DOI":"10.1097\/00005344-198500073-00011","volume":"7","author":"A Bill","year":"1985","unstructured":"Bill A, Nilsson SFE (1985) Control of ocular blood flow. J Cardiovasc Pharmacol 7 [suppl 3]:S96-S102","journal-title":"J Cardiovasc Pharmacol"},{"key":"CR3","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1111\/j.1600-0536.1994.tb00565.x","volume":"30","author":"A Bircher","year":"1994","unstructured":"Bircher A, De Boer EM, Agner T, Wahlberg JE, Serup J (1994) Guidelines for measurement of cutaneous blood flow by laser Doppler flowmetry. Contact Dermatitis 30:65?72","journal-title":"Contact Dermatitis"},{"key":"CR4","first-page":"596","volume":"36","author":"SE Bursell","year":"1995","unstructured":"Bursell SE, Clermont AC, Oren B, King GL (1995) The in vivo effect of endothelins on retinal circulation in nondiabetic and diabetic rats. Invest Ophthalmol Vis Sci 36:596?607","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"CR5","doi-asserted-by":"crossref","first-page":"1430","DOI":"10.1016\/0140-6736(92)92621-L","volume":"340","author":"PJ Chowienczyk","year":"1992","unstructured":"Chowienczyk PJ, Watts GF, Cockcroft JR, Ritter JM (1992) Impaired endothelium-dependent vasodilation of forearm resistance vessels in hypercholesterolemia. Lancet 340:1430?1432","journal-title":"Lancet"},{"key":"CR6","doi-asserted-by":"crossref","first-page":"E97","DOI":"10.1152\/ajpcell.1978.235.3.C97","volume":"235","author":"A Lean De","year":"1978","unstructured":"De Lean A, Munson PJ, Rodbard D (1978) Simultaneous analysis of families of sigmoidal curves: application to bioassay, radioligand assay, and physiological dose-response curves. Am J Physiol 235:E97-E102","journal-title":"Am J Physiol"},{"key":"CR7","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1161\/01.HYP.18.4.543","volume":"18","author":"Y Dohi","year":"1991","unstructured":"Dohi Y, L\u00fcscher TF (1991) Endothelin in hypertensive resistance arteries. Intraluminal and extraluminal dysfunction. Hypertension 18:543?549","journal-title":"Hypertension"},{"key":"CR8","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/0002-9394(88)90118-3","volume":"105","author":"SM Drance","year":"1988","unstructured":"Drance SM, Douglas GR, Wijsman K, Schulzer M, Britton RJ (1988) Response of blood flow to warm and cold in normal and low-tension glaucoma patients. Am J Ophthalmol 105:35?39","journal-title":"Am J Ophthalmol"},{"key":"CR9","first-page":"12","volume-title":"Ocular blood flow. Glaucoma Meeting","author":"J Flammer","year":"1995","unstructured":"Flammer J (1995) To what extent are vascular factors involved in the pathogenesis of glaucoma? In: Kaiser HJ, Flammer J, Hendrickson P (eds) Ocular blood flow. Glaucoma Meeting. Karger, Basel, pp 12?39"},{"key":"CR10","unstructured":"Flammer J, Org\u00fcl S (1997) Optic nerve blood flow abnormalities in glaucoma. Prog Retin Res (in press)"},{"key":"CR11","first-page":"4268","volume":"35","author":"C Fl\u00fcgel-Koch","year":"1994","unstructured":"Fl\u00fcgel-Koch C, Kaufman P, L\u00fctjen-Drecoll E (1994) Association of a choroidal ganglion cell plexus with the fovea centralis. Invest Ophthalmol Vis Sci 35:4268?4272","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"CR12","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1016\/S0002-9394(14)73703-1","volume":"111","author":"P Gasser","year":"1991","unstructured":"Gasser P, Flammer J (1991) Blood-cell velocity in the nailfold capillaries of patients with normal-tension and high-tension glaucoma. Am J Ophthalmol 111:585?588","journal-title":"Am J Ophthalmol"},{"key":"CR13","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1007\/BF02181185","volume":"226","author":"U Guthauser","year":"1988","unstructured":"Guthauser U, Flammer J, Mahler F (1988) The relationship between digital and ocular vasospasm. Graefe's Arch Clin Exp Ophthalmol 226:224?226","journal-title":"Graefe's Arch Clin Exp Ophthalmol"},{"key":"CR14","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/0039-6257(94)90157-0","volume":"39","author":"IO Haefliger","year":"1994","unstructured":"Haefliger IO, Meyer P, Flammer J, L\u00fcscher TF (1994) The vascular endothelium as a regulator of the ocular circulation: a new concept in ophthalmology? Surv Ophthalmol 39:123?132","journal-title":"Surv Ophthalmol"},{"key":"CR15","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1016\/S0014-4835(05)80121-6","volume":"61","author":"SS Hayreh","year":"1995","unstructured":"Hayreh SS (1995) The optic nerve head circulation in health and disease. Exp Eye Res 61:259?272","journal-title":"Exp Eye Res"},{"key":"CR16","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1161\/01.CIR.90.1.17","volume":"90","author":"C Indolfi","year":"1994","unstructured":"Indolfi C, Maione AG, Volpe M, Rapacciuolo A, Esposito G, Ceravolo R, Rendina V, Condorelli M, Chiariello M (1994) Forearm vascular responsiveness to ?1- and ?2-adrenoceptor stimulation in patients with congestive heart failure. Circulation 90:17?22","journal-title":"Circulation"},{"key":"CR17","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1007\/BF00919280","volume":"231","author":"HJ Kaiser","year":"1993","unstructured":"Kaiser HJ, Flammer J, Graf T, St\u00fcmpfig D (1993) Systemic blood pressure in glaucoma patients. Graefe's Arch Clin Exp Ophthalmol 231:677?680","journal-title":"Graefe's Arch Clin Exp Ophthalmol"},{"key":"CR18","doi-asserted-by":"crossref","first-page":"484","DOI":"10.1007\/BF00183429","volume":"233","author":"HJ Kaiser","year":"1995","unstructured":"Kaiser HJ, Flammer J, Wenk M, L\u00fcscher TF (1995) Endothelin-1 plasma levels in normal-tension glaucoma: abnormal response to postural changes. Graefe's Arch Clin Exp Ophthalmol 233:484?488","journal-title":"Graefe's Arch Clin Exp Ophthalmol"},{"key":"CR19","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1016\/S0014-4835(05)80109-5","volume":"60","author":"JW Kiel","year":"1995","unstructured":"Kiel JW (1995) The effect of arterial pressure on the ocular pressure-volume relationship in the rabbit. Exp Eye Res 60:267?278","journal-title":"Exp Eye Res"},{"key":"CR20","doi-asserted-by":"crossref","first-page":"1063","DOI":"10.1016\/0002-9149(92)90864-U","volume":"69","author":"W Kiowski","year":"1992","unstructured":"Kiowski W, Linder L (1992) Reversal of endothelin-l-induced vasoconstriction by nifedipine in human resistance vessels in vivo in healthy subjects. Am J Cardiol 69:1063?1066","journal-title":"Am J Cardiol"},{"key":"CR21","doi-asserted-by":"crossref","first-page":"1762","DOI":"10.1161\/01.CIR.81.6.1762","volume":"81","author":"L Linder","year":"1990","unstructured":"Linder L, Kiowski W, B\u00fchler FR, L\u00fcscher TF (1990) Indirect evidence for release of endothelium-derived relaxing factor in human forearm circulation in vivo. Blunted response in essential hypertension. Circulation 81:1762?1767","journal-title":"Circulation"},{"key":"CR22","doi-asserted-by":"crossref","first-page":"1231","DOI":"10.1001\/archopht.1994.01090210119024","volume":"112","author":"MW MacCumber","year":"1994","unstructured":"MacCumber MW, D'Anna SA (1994) Endothelin receptor-binding subtypes in the human retina and choroid. Arch Ophthalmol 112:1231?1235","journal-title":"Arch Ophthalmol"},{"key":"CR23","first-page":"3614","volume":"34","author":"P Meyer","year":"1993","unstructured":"Meyer P, Flammer J, L\u00fcscher TF (1993) Endothelium-dependent regulation of the ophthalmic microcirculation in the perfused porcine eye: role of nitric oxide and endothelins. Invest Ophthalmol Vis Sci 34:3614?3621","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"CR24","first-page":"554","volume":"43","author":"S Moriya","year":"1992","unstructured":"Moriya S, Sugiyama T, Shimizu K, Hamada J, Tokuoka S, Azuma I (1992) Low-tension glaucoma and endothelin (ET-1). Folia Ophthalmol Jpn 43:554?559","journal-title":"Folia Ophthalmol Jpn"},{"key":"CR25","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/S0014-4835(05)80081-8","volume":"60","author":"Y Nakanome","year":"1995","unstructured":"Nakanome Y, Karita K, Izumi H, Tamai M (1995) Two types of vasodilation in cat choroid elicited by electrical stimulation of the short ciliary nerve. Exp Eye Res 60:37?42","journal-title":"Exp Eye Res"},{"key":"CR26","first-page":"427","volume":"4","author":"S Org\u00fcl","year":"1995","unstructured":"Org\u00fcl S, Meyer P, Cioffi GA (1995) Physiology of blood flow regulation and mechanisms involved in optic nerve perfusion. J Glaucoma 4:427?443","journal-title":"J Glaucoma"},{"key":"CR27","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1056\/NEJM199007053230105","volume":"323","author":"JA Panza","year":"1990","unstructured":"Panza JA, Quyyumi AA, Brush JE, Epstein SE (1990) Normal endothelium-dependent vascular relaxation in patients with essential hypertension. N Engl J Med 323:22?27","journal-title":"N Engl J Med"},{"key":"CR28","first-page":"138","volume-title":"Ocular blood flow Glaucoma Meeting","author":"LE Pillunat","year":"1996","unstructured":"Pillunat LE, Anderson DR, Knighton RW, Joos KM, Feuer WJ (1996) Autoregulation of ocular blood flow. In: Kaiser HL, Flammer J, Hendrickson P (eds) Ocular blood flow Glaucoma Meeting. Karger, Basel, pp 138?144"},{"key":"CR29","first-page":"40","volume-title":"Ocular blood flow. Glaucoma Meeting","author":"CJ Pournaras","year":"1996","unstructured":"Pournaras CJ (1996) Autoregulation of ocular blood flow. In: Kaiser HL, Flammer J, Hendrickson P (eds) Ocular blood flow. Glaucoma Meeting. Karger, Basel, pp 40?50"},{"key":"CR30","first-page":"469","volume":"166","author":"EM Redmond","year":"1996","unstructured":"Redmond EM, Cahill PA, Hodges R, Zhang S, Sitzmann JV (1996) Regulation of endothelin receptors by nitric oxide in cultured rat vascular smooth muscle cells. J Cell Biol 166:469?479","journal-title":"J Cell Biol"},{"key":"CR31","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1016\/0014-4835(92)90123-A","volume":"55","author":"CE Riva","year":"1992","unstructured":"Riva CE, Harino S, Petrig BL, Shonat RD (1992) Laser Doppler flowmetry in the optic nerve. Exp Eye Res 55:499?506","journal-title":"Exp Eye Res"},{"key":"CR32","doi-asserted-by":"crossref","first-page":"S23","DOI":"10.1016\/0039-6257(94)90044-2","volume":"38","author":"B Schwartz","year":"1994","unstructured":"Schwartz B (1994) Circulatory defects of the optic disk and retina in ocular hypertension and high pressure open-angle glaucoma. Surv Ophthalmol 38 [Suppl]:S23-S34","journal-title":"Surv Ophthalmol"},{"key":"CR33","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1097\/00004872-199205000-00006","volume":"10","author":"EL Schiffrin","year":"1992","unstructured":"Schiffrin EL, Deng LY, Larochelle P (1992) Blunted effects of endothelin upon small subcutaneous resistance arteries of mild essential hypertensive patients. J Hypertension 10:437?444","journal-title":"J Hypertension"},{"key":"CR34","doi-asserted-by":"crossref","first-page":"997","DOI":"10.1016\/S0140-6736(89)91013-1","volume":"ii","author":"P Vallance","year":"1989","unstructured":"Vallance P, Collier J, Moncada S (1989) Effects of endothelium-derived nitric oxide on peripheral arteriolar tone in man. Lancet ii:997?1000","journal-title":"Lancet"},{"key":"CR35","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1161\/01.HYP.23.5.581","volume":"23","author":"RR Wenzel","year":"1994","unstructured":"Wenzel RR, Noll G, L\u00fcscher TF (1994) Endothelin receptor antagonists inhibit endothelin in human skin microcirculation. Hypertension 23:581?586","journal-title":"Hypertension"},{"key":"CR36","doi-asserted-by":"crossref","first-page":"939","DOI":"10.1136\/bjo.78.12.939","volume":"78","author":"TH Williamson","year":"1994","unstructured":"Williamson TH, Harris A (1994) Ocular blood flow measurement. Br J Ophthalmol 78:939?945","journal-title":"Br J Ophthalmol"},{"key":"CR37","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1161\/01.CIR.82.1.188","volume":"82","author":"Z Yang","year":"1990","unstructured":"Yang Z, Richard V, von Segesser L, Bauer E, Stulz P, Turina M, L\u00fcscher TF (1990) Threshold concentrations of endothelin-1 potentiate contractions to norepinephrine and serotonin in human arteries. A new mechanism of vasospasm? Circulation 82:188?195","journal-title":"Circulation"}],"container-title":["Graefe's Archive for Clinical and Experimental Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF00946939.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/BF00946939\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF00946939","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,4,29]],"date-time":"2019-04-29T20:12:08Z","timestamp":1556568728000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/BF00946939"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1997,10]]},"references-count":37,"journal-issue":{"issue":"10","published-print":{"date-parts":[[1997,10]]}},"alternative-id":["BF00946939"],"URL":"https:\/\/doi.org\/10.1007\/bf00946939","relation":{},"ISSN":["0721-832X","1435-702X"],"issn-type":[{"value":"0721-832X","type":"print"},{"value":"1435-702X","type":"electronic"}],"subject":[],"published":{"date-parts":[[1997,10]]}}}