{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,21]],"date-time":"2025-09-21T18:18:36Z","timestamp":1758478716317},"reference-count":30,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[1992,4,1]],"date-time":"1992-04-01T00:00:00Z","timestamp":702086400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neurochem Res"],"published-print":{"date-parts":[[1992,4]]},"DOI":"10.1007\/bf00974576","type":"journal-article","created":{"date-parts":[[2005,1,14]],"date-time":"2005-01-14T07:51:27Z","timestamp":1105689087000},"page":"345-350","source":"Crossref","is-referenced-by-count":12,"title":["High-affinity transport of choline and amino acid neurotransmitters in synaptosomes from brain regions after lesioning the nucleus basalis magnocellularis of young and aged rats"],"prefix":"10.1007","volume":"17","author":[{"given":"J.","family":"Gomeza","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Arag\ufffdn","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Gim\ufffdnez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"CR1","doi-asserted-by":"crossref","first-page":"408","DOI":"10.1126\/science.7046051","volume":"217","author":"R. T. Bartus","year":"1982","unstructured":"Bartus, R. T., Dean, R. L. III, Beer, B., and Lippa, A. S. 1982. The cholinergic hypothesis of geriatric memory dysfunction. Science 217:408?417.","journal-title":"Science"},{"key":"CR2","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/0091-3057(85)90139-X","volume":"23","author":"R. T. Bartus","year":"1985","unstructured":"Bartus, R. T., Flicker, C., Dean, R. L., Pontecorvo, M., Figueiredo, J. C., and Fisher, S. K. 1985. Selective memory loss following nucleus basalis lesions: long term behavioral recovery despite persistent cholinergic deficiencies. Pharmacol. Biochem. Behav. 23:125?135.","journal-title":"Pharmacol. Biochem. Behav."},{"key":"CR3","doi-asserted-by":"crossref","first-page":"1184","DOI":"10.1126\/science.6338589","volume":"219","author":"J. T. Coyle","year":"1983","unstructured":"Coyle, J. T., Price, D. L., and DeLong, M. R. 1983. Alzheimer's disease: a disorder of cortical cholinergic innervation. Science 219:1184?1190.","journal-title":"Science"},{"key":"CR4","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/0306-4522(85)90160-5","volume":"14","author":"T. Arendt","year":"1985","unstructured":"Arendt, T., Bigl, V., Tennstedt, A., and Arendt, A. 1985. Neuronal loss in different parts of the nucleus basalis is related to neuritic plaque formation in cortical target areas in Alzheimer's disease. Neuroscience 14:1?14.","journal-title":"Neuroscience"},{"key":"CR5","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1016\/0361-9230(86)90134-6","volume":"16","author":"N. J. Woolf","year":"1986","unstructured":"Woolf, N. J., and Butcher, L. L. 1986. Cholinergic systems in the rat brain. III. Projections from the pontomesencephalic tegmentum to the thalamus, tectum, basal ganglia, and basal forebrain. Brain. Res. Bull. 16:603?607.","journal-title":"Brain. Res. Bull."},{"key":"CR6","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1016\/0304-3940(86)90032-7","volume":"66","author":"N. J. Woolf","year":"1986","unstructured":"Woolf, N. J., Hernit, M. C., and Butcher, L. L. 1986. Cholinergic and non-cholinergic projections from the rat basal forebrain revealed by combined choline acetyltransferase andPhaseolus vulgaris leucoagglutinin immunohistochemistry. Neurosci. Lett. 66:281?286.","journal-title":"Neurosci. Lett."},{"key":"CR7","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1002\/cne.902160106","volume":"216","author":"D. M. Armstrong","year":"1983","unstructured":"Armstrong, D. M., Saper, C. B., Levey, A. I., Waiver, H., and Terry, R. D. 1983. Distribution of cholinergic neurons in rat demonstrated by the immunocytochemical localization of choline acetyltransferase. J. Comp. Neurol. 216:53?68.","journal-title":"J. Comp. Neurol."},{"key":"CR8","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1016\/0165-0173(82)90011-X","volume":"4","author":"H. C. Fibriger","year":"1982","unstructured":"Fibriger, H. C. 1982. The organization and some projections of cholinergic neurons of the mammalian forebrain. Brain. Res. Rev. 4:327?388.","journal-title":"Brain. Res. Rev."},{"key":"CR9","doi-asserted-by":"crossref","first-page":"1185","DOI":"10.1016\/0306-4522(83)90108-2","volume":"10","author":"M. M. Mesulam","year":"1983","unstructured":"Mesulam, M. M., Mufson, E. J., Waiver, B. H., and Levey, A. I. 1983. Central cholinergic pathways in the rat: an overview based on an alternative nomenclature (Ch1-Ch6). Neuroscience 10:1185?1201.","journal-title":"Neuroscience"},{"key":"CR10","doi-asserted-by":"crossref","first-page":"2369","DOI":"10.1016\/0306-4522(82)90201-9","volume":"7","author":"S. L. Hartgraves","year":"1982","unstructured":"Hartgraves, S. L., Mensch, P. L., and Kelly, P. H. 1982. Regional decreases in cortical choline acetyltransferase after lesion of septal area in the area of the nucleus basalis magnocellularis. Neuroscience 7:2369?2376.","journal-title":"Neuroscience"},{"key":"CR11","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1007\/BF00237760","volume":"43","author":"M. V. Johnston","year":"1981","unstructured":"Johnston, M. V., McKinney, M., and Coyle, J. T. 1981. Neurocortical cholinergic innervation: a description of extrinsic and intrinsic components in the rat. Exp. Brain. Res. 43:159?172.","journal-title":"Exp. Brain. Res."},{"key":"CR12","doi-asserted-by":"crossref","first-page":"5392","DOI":"10.1073\/pnas.76.10.5392","volume":"76","author":"M. V. Johnston","year":"1979","unstructured":"Johnston, M. V., McKinney, M., and Coyle, J. T. 1979. Evidence for a cholinergic projection to neurocortex from neurons in basal forebrain. Proc. Natl. Acad. Sci. U.S.A. 76:5392?5396.","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"CR13","doi-asserted-by":"crossref","first-page":"1237","DOI":"10.1126\/science.7058341","volume":"215","author":"P. J. Whitehouse","year":"1982","unstructured":"Whitehouse, P. J., Price, D. L., Struble, R. G., Clark, A. W., and DeLong, M. R. 1982. Alzheimer's disease and senile dementia: loss of neurons in the basal forebrain. Science 215:1237?1239.","journal-title":"Science"},{"key":"CR14","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1007\/BF01245715","volume":"71","author":"M. D. C. Simpson","year":"1988","unstructured":"Simpson, M. D. C., Cross, A. J., Slater, P., and Deakin, J. F. W. 1988. Loss of cortical GABA uptake sites in Alzheimer's disease. J. Neural Transmission 71:219?226.","journal-title":"J. Neural Transmission"},{"key":"CR15","doi-asserted-by":"crossref","first-page":"2745","DOI":"10.1096\/fasebj.4.10.2165009","volume":"4","author":"A. M. Palmer","year":"1990","unstructured":"Palmer, A. M., and Gerson, S. 1990. Is the neuronal basis of Alzheimer's disease cholinergic or glutamatergic? FASEB J. 4:2745?2752.","journal-title":"FASEB J."},{"key":"CR16","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1111\/j.1476-5381.1971.tb07066.x","volume":"41","author":"L. L. Iversen","year":"1971","unstructured":"Iversen, L. L. 1971. Role of transmitter uptake mechanism in synaptic transmission. Br. J. Pharmacol. 41:571?591.","journal-title":"Br. J. Pharmacol."},{"key":"CR17","volume-title":"The rat brain in stereotaxic coordinates","author":"G. Paxinos","year":"1986","unstructured":"Paxinos, G., and Watson, C. 1986. The rat brain in stereotaxic coordinates, Academic Press, New York."},{"key":"CR18","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1111\/j.1471-4159.1966.tb09873.x","volume":"13","author":"J. Glowinsky","year":"1966","unstructured":"Glowinsky, J., and Iversen, L. L. 1966. Regional studies of catecholamines in the brain I. J. Neurochem. 13:655?669.","journal-title":"J. Neurochem."},{"key":"CR19","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1042\/bj1760365","volume":"176","author":"R. F. G. Booth","year":"1978","unstructured":"Booth, R. F. G., and Clark, J. B. 1978. A rapid method for the preparation of relatively pure metabolically competent synaptosomes from rat brain. Biochem. J. 176:365?370.","journal-title":"Biochem. J."},{"key":"CR20","doi-asserted-by":"crossref","first-page":"1366","DOI":"10.1111\/j.1471-4159.1989.tb09181.x","volume":"52","author":"J. Diez-Guerra","year":"1989","unstructured":"Diez-Guerra, J., and Gim\u00e9nez, C. 1989. Na+-dependence of tyrosine transport across the synaptosomal membrane reflects changes in the morphology of synaptosomes. J. Neurochem. 52:1366?1374.","journal-title":"J. Neurochem."},{"key":"CR21","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/S0021-9258(19)52451-6","volume":"193","author":"O. H. Lowry","year":"1951","unstructured":"Lowry, O. H., Rosebrough, N. J., Farr, A. L., and Randall, R. J. 1951. Protein measurements with the folin phenol reagent. J. Biol. Chem. 193:265?275.","journal-title":"J. Biol. Chem."},{"key":"CR22","first-page":"3","volume-title":"Biology of cholinergic function","author":"M. T. Kuhar","year":"1976","unstructured":"Kuhar, M. T. 1976. The anatomy of cholinergic neurons. Pages 3?27,in Goldberg, A. M., and Hanin, I. (eds.), Biology of cholinergic function. Raven Press, New York."},{"key":"CR23","doi-asserted-by":"crossref","first-page":"1534","DOI":"10.1016\/0024-3205(75)90174-5","volume":"17","author":"S. F. Atweh","year":"1975","unstructured":"Atweh, S. F., Simon, J. R., and Kuhar, M. J. 1975. Utilization of sodium-dependent high-affinity choline uptake as a measure of the activity of cholinergic neurons in vivo. Life Sci. 17:1534?1544.","journal-title":"Life Sci."},{"key":"CR24","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1111\/j.1476-5381.1981.tb10460.x","volume":"74","author":"T. Antonelli","year":"1981","unstructured":"Antonelli, T., Beani, C., Pedata, F., and Pepeu, G. 1981. Changes in synaptosomal high affinity choline uptake following electrical stimulation of guinea-pig slices: effect of atropine and physostigmine. Br. J. Pharmac. 74:525?531.","journal-title":"Br. J. Pharmac."},{"key":"CR25","doi-asserted-by":"crossref","first-page":"952","DOI":"10.1126\/science.2890210","volume":"238","author":"G. W. Arendash","year":"1987","unstructured":"Arendash, G. W., Millard, W. J., Dunn, A. J., and Meyer, E. M. 1987. Long-term neuropathological and neurochemical effects of the nucleus basalis lesions in the rat. Science 238:952?956.","journal-title":"Science"},{"key":"CR26","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1016\/0306-4522(88)90324-7","volume":"24","author":"F. Casamenti","year":"1988","unstructured":"Casamenti, F., Di Patre, P. L., Bartolini, L., and Pepeu, G. 1988. Unilateral and bilateral nucleus basalis lesions: differences in neurochemical and behavioral recovery. Neuroscience 24:209?215.","journal-title":"Neuroscience"},{"key":"CR27","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1016\/0006-8993(84)91468-9","volume":"293","author":"G. L. Wenk","year":"1984","unstructured":"Wenk, G. L., and Olton, D. S. 1984. Recovery of neocortical choline acetyltransferase activity following ibotenic acid injection into the nucleus basalis of Meynert in rats. Brain Res. 293:184?186.","journal-title":"Brain Res."},{"key":"CR28","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1002\/cne.902050304","volume":"205","author":"S. F. Hoff","year":"1982","unstructured":"Hoff, S. F., Scheff, S. W., Bernardo, L. S., and Cotman, C. W. 1982. Lesion-induced synaptogenesis in the dentate gyrus of aged rats: I. Loss and reacquisition of normal synaptic density. J. Comp. Neurol. 205:246?252.","journal-title":"J. Comp. Neurol."},{"key":"CR29","first-page":"39","volume":"1","author":"W. Fisher","year":"1989","unstructured":"Fisher, W., Cage, F. H., and Bj\u00f6rklund, A. 1989. Degenerative changes in forebrain cholinergic nuclei correlate with cognitive impairment in aged rats. Eur. J. Neursc. 1:39?44.","journal-title":"Eur. J. Neursc."},{"key":"CR30","doi-asserted-by":"crossref","first-page":"4531","DOI":"10.1073\/pnas.82.13.4531","volume":"82","author":"R. C. A. Pearson","year":"1988","unstructured":"Pearson, R. C. A., Esiri, M. M., Hiors, R. W., Wilcok, G. K., and Powell, T. P. S. 1988. Anatomical correlates of the distribution of the pathological changes in the neocortex in Alzheimer disease. Proc. Natl. Acad. Sci. U.S.A. 82:4531?4534.","journal-title":"Proc. Natl. Acad. Sci. U.S.A."}],"container-title":["Neurochemical Research"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF00974576.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/BF00974576\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF00974576","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,7,4]],"date-time":"2021-07-04T01:17:44Z","timestamp":1625361464000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/BF00974576"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1992,4]]},"references-count":30,"journal-issue":{"issue":"4","published-print":{"date-parts":[[1992,4]]}},"alternative-id":["BF00974576"],"URL":"https:\/\/doi.org\/10.1007\/bf00974576","relation":{},"ISSN":["0364-3190","1573-6903"],"issn-type":[{"value":"0364-3190","type":"print"},{"value":"1573-6903","type":"electronic"}],"subject":[],"published":{"date-parts":[[1992,4]]}}}