{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T10:29:03Z","timestamp":1761560943222},"reference-count":45,"publisher":"Springer Science and Business Media LLC","issue":"9","license":[{"start":{"date-parts":[[1988,9,1]],"date-time":"1988-09-01T00:00:00Z","timestamp":589075200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Histochem J"],"published-print":{"date-parts":[[1988,9]]},"DOI":"10.1007\/bf01002646","type":"journal-article","created":{"date-parts":[[2005,1,18]],"date-time":"2005-01-18T16:27:11Z","timestamp":1106065631000},"page":"478-490","source":"Crossref","is-referenced-by-count":50,"title":["Elderberry bark lectin-gold techniques for the detection of Neu5Ac (?2,6) Gal\/GalNAc sequences: applications and limitations"],"prefix":"10.1007","volume":"20","author":[{"given":"D. J.","family":"Taatjes","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Roth","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"W.","family":"Peumans","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"I. J.","family":"Goldstein","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"CR1","doi-asserted-by":"crossref","first-page":"4000","DOI":"10.1016\/S0021-9258(18)50686-4","volume":"254","author":"V. P. Bhavanandan","year":"1979","unstructured":"Bhavanandan, V. P. &Katlic, A. W. (1979) The interaction of wheat germ agglutinin with sialoglycoproteins. The role of sialic acid.J. Biol. Chem. 254, 4000?8.","journal-title":"J. Biol. Chem."},{"key":"CR2","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1042\/bj2210163","volume":"221","author":"W. F. Broekaert","year":"1984","unstructured":"Broekaert, W. F., Nsimba-Lubaki, M., Peeters, B. &Peumans, W. J. (1984) A lectin from elder (Sambucus nigra L.) bark.Biochem. J. 221, 163?9.","journal-title":"Biochem. J."},{"key":"CR3","doi-asserted-by":"crossref","first-page":"8508","DOI":"10.1073\/pnas.82.24.8508","volume":"82","author":"P. Charest","year":"1985","unstructured":"Charest, P. &Roth, J. (1985) Localization of sialic acid in kidney glomeruli: regionalization in the podocyte plasma membrane and loss in experimental nephrosis.Proc. Natl. Acad. Sci. USA 82, 8508?12.","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"CR4","doi-asserted-by":"crossref","first-page":"7453","DOI":"10.1016\/S0021-9258(17)42812-2","volume":"259","author":"D. A. Cheresh","year":"1984","unstructured":"Cheresh, D. A., Varki, A. P., Varki, N. M., Stallcup, W. B., Levine, J. &Reisfeld, R. A. (1984) A monoclonal antibody recognizes anO-acetylated sialic acid in a human melanoma-associated ganglioside.J. Biol. Chem. 259, 7453?9.","journal-title":"J. Biol. Chem."},{"key":"CR5","doi-asserted-by":"crossref","first-page":"1321","DOI":"10.1007\/BF01002529","volume":"17","author":"A. Ellinger","year":"1985","unstructured":"Ellinger, A. &Pavelka, M. (1985) Post-embedding localization of glycoconjugates by means of lectins on thin sections of tissues embedded in LR White.Histochem. J. 17, 1321?36.","journal-title":"Histochem. J."},{"key":"CR6","doi-asserted-by":"crossref","first-page":"1194","DOI":"10.1073\/pnas.82.4.1194","volume":"82","author":"M. Frosch","year":"1985","unstructured":"Frosch, M., G\u00f6rgen, I., Boulnqis, G. J., Timmis, K. N. &Bitter-Suermann, D. (1985) NZB mouse system for production of monoclonal antibodies to weak bacterial antigens: isolation of an IgG antibody to the polysaccharide capsules ofE. coli K1 and group B meningococci.Proc. Natl. Acad. Sci. USA 82, 1194?8.","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"CR7","first-page":"35","volume-title":"The Lectins. Properties, Functions, and Applications in Biology and Medicine","author":"I. J. Goldstein","year":"1986","unstructured":"Goldstein, I. J. &Poretz, R. D. (1986) Isolation, physiochemical characterization, and carbohydrate-bindinding specificity of lectins. InThe Lectins. Properties, Functions, and Applications in Biology and Medicine (edited byLiener, I. E., Sharon, N. &Goldstein, I. J.), pp. 35?247. London: Academic Press."},{"key":"CR8","doi-asserted-by":"crossref","first-page":"380","DOI":"10.1016\/0006-3002(59)90290-2","volume":"34","author":"A. Gottschalk","year":"1959","unstructured":"Gottschalk, A. &Graham, E. R. B. (1959) 6-?-D-sialyl-N-acetylgalactosamine: the neuraminidase-susceptible prosthetic group of bovine salivary mucoprotein.Biochim. Biophys. Acta 34, 380?91.","journal-title":"Biochim. Biophys. Acta"},{"key":"CR9","doi-asserted-by":"crossref","first-page":"11819","DOI":"10.1016\/S0021-9258(17)44304-3","volume":"258","author":"S. Hakomori","year":"1983","unstructured":"Hakomori, S., Patterson, C. M., Nudelman, E. &Sekiguchi, K. (1983) A monoclonal antibody directed toN-acetylneuraminosyl-?2,6-galactosyl residue in gangliosides and glycoproteins.J. Biol. Chem. 258, 11819?22.","journal-title":"J. Biol. Chem."},{"key":"CR10","doi-asserted-by":"crossref","first-page":"1069","DOI":"10.1177\/34.8.3734417","volume":"34","author":"K. Hedman","year":"1986","unstructured":"Hedman, K., Pastan, I. &Willingham, M. C. (1986) The organelles of thetrans domain of the cell. Ultrastructural localization of sialoglycoconjugates usingLimax flavus agglutinin.J. Histochem. Cytochem. 34, 1069?77.","journal-title":"J. Histochem. Cytochem."},{"key":"CR11","doi-asserted-by":"crossref","first-page":"3791","DOI":"10.1016\/S0021-9258(17)40321-8","volume":"252","author":"H. D. Hill Jr","year":"1977","unstructured":"Hill, H. D. Jr, Reynolds, J. A. &Hill, R. L. (1977) Purification, composition, molecular weight, and subunit structure of ovine submaxillary mucin.J. Biol. Chem. 252, 3791?8.","journal-title":"J. Biol. Chem."},{"key":"CR12","doi-asserted-by":"crossref","first-page":"680","DOI":"10.1038\/227680a0","volume":"227","author":"U. K. Laemmli","year":"1970","unstructured":"Laemmli, U. K. (1970) Cleavage of structural proteins during the assembly of the head of bacteriophage T4.Nature 227, 680?5.","journal-title":"Nature"},{"key":"CR13","doi-asserted-by":"crossref","first-page":"795","DOI":"10.1016\/0006-291X(87)90946-6","volume":"148","author":"C. Mandal","year":"1987","unstructured":"Mandal, C. &Basu, S., (1987) An unique specificity of a sialic acid binding lectin AchitininH from the hemolymph ofAchatina fulica snail.Biochem. Biophys. Res. Commun. 148, 795?801.","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"CR14","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1016\/0022-2836(68)90022-3","volume":"32","author":"J. J. Marchalonis","year":"1968","unstructured":"Marchalonis, J. J. &Edelman, G. M. (1968) Isolation and characterization of a hemagglutinin fromLimulus polyphemus.J. Mol. Biol. 32, 453?65.","journal-title":"J. Mol. Biol."},{"key":"CR15","doi-asserted-by":"crossref","first-page":"470","DOI":"10.1177\/25.6.328765","volume":"25","author":"M. Mazzuca","year":"1977","unstructured":"Mazzuca, M., Roche, A.-C., Lhermitte, M. &Rossel, P. (1977)Limulus polyphemus lectin sites in human bronchial mucosa.J. Histochem. Cytochem. 25, 470?2.","journal-title":"J. Histochem. Cytochem."},{"key":"CR16","doi-asserted-by":"crossref","first-page":"7574","DOI":"10.1016\/S0021-9258(18)34418-1","volume":"257","author":"R. L. Miller","year":"1982","unstructured":"Miller, R. L., Collawan, J. F. &Fish, W. W. (1982) Purification and macromolecular properties of a sialic acid-specific lectin from the slugLimax flavus.J. Biol. Chem. 257, 7574?80.","journal-title":"J. Biol. Chem."},{"key":"CR17","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1007\/BF02716854","volume":"5","author":"S. Mohan","year":"1983","unstructured":"Mohan, S., Dorai, D. T., Srimal, S., Bachhawat, B. K. &Das, M. K. (1983) Fluorescence studies on the interaction of some ligands with carcinoscorpin, the sialic acid specific lectin, from the horseshoe crab,Carcinoscorpius rotundacauda.J. Biosci. 5, 155?62.","journal-title":"J. Biosci."},{"key":"CR18","doi-asserted-by":"crossref","first-page":"938","DOI":"10.1177\/30.9.6897073","volume":"30","author":"V. Muresan","year":"1982","unstructured":"Muresan, V., Iwanij, V., Smith, Z. D. J. &Jamieson, J. D. (1982a) Purification and use of limulin: a sialic acid-specific lectin.J. Histochem. Cytochem. 30, 938?46.","journal-title":"J. Histochem. Cytochem."},{"key":"CR19","doi-asserted-by":"crossref","first-page":"947","DOI":"10.1177\/30.9.6752268","volume":"30","author":"V. Muresan","year":"1982","unstructured":"Muresan, V., Sarras, M. P. Jr. &Jamieson, J. D. (1982b) Distribution of sialoglycoconjugates on acinar cells of the mammalian pancreas.J. Histochem. Cytochem. 30, 947?55.","journal-title":"J. Histochem. Cytochem."},{"key":"CR20","doi-asserted-by":"crossref","first-page":"5505","DOI":"10.1021\/bi00591a038","volume":"18","author":"B. P. Peters","year":"1979","unstructured":"Peters, B. P., Ebisu, S., Goldstein, I. J. &Flashner, M. (1979) Interaction of wheat germ agglutinin with sialic acid.Biochemistry 18, 5505?11.","journal-title":"Biochemistry"},{"key":"CR21","doi-asserted-by":"crossref","first-page":"8850","DOI":"10.1016\/S0021-9258(17)39429-2","volume":"260","author":"M. H. Ravindranath","year":"1985","unstructured":"Ravindranath, M. H., Higa, H. H., Cooper, E. L. &Paulson, J. C. (1985) Purification and characterization of anO-acetylsialic acid-specific lectin from a marine crabCancer antennarius.J. Biol. Chem. 260, 8850?6.","journal-title":"J. Biol. Chem."},{"key":"CR22","doi-asserted-by":"crossref","first-page":"7362","DOI":"10.1016\/S0021-9258(17)39617-5","volume":"260","author":"G. N. Rogers","year":"1985","unstructured":"Rogers, G. N., Daniels, R. S., Skehel, J. J., Wiley, D. C., Wang, X. F., Higa, H. H. &Paulson, J. C. (1985) Host-mediated selection of influenza virus receptor variants. Sialic acid-?2,6 Gal-specific clones of A\/Duck\/Ukraine\/1\/63 revert to sialic acid-?2,3 Gal-specific wild typein ovo.J. Biol. Chem. 260, 7362?7.","journal-title":"J. Biol. Chem."},{"key":"CR23","doi-asserted-by":"crossref","first-page":"5947","DOI":"10.1016\/S0021-9258(17)38475-2","volume":"261","author":"G. N. Rogers","year":"1986","unstructured":"Rogers, G. N., Herrler, G., Paulson, J. C. &Klenk, H.-D. (1986) Influenza C virus uses 9-O-acetyl-N-acetylneuraminic acid as a high affinity receptor determinant for attachment to cells.J. Biol. Chem. 261, 5947?51.","journal-title":"J. Biol. Chem."},{"key":"CR24","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1177\/31.4.6186737","volume":"31","author":"J. Roth","year":"1983","unstructured":"Roth, J. (1983) Application of immunocolloids in light microscopy. II. Demonstration of lectin binding sites in paraffin sections by the use of lectin-gold complexes or glycoprotein-gold complexes.J. Histochem. Cytochem. 31, 547?52.","journal-title":"J. Histochem. Cytochem."},{"key":"CR25","first-page":"695","volume":"1","author":"J. Roth","year":"1987","unstructured":"Roth, J. (1987) Light and electron microscopic localization of glycoconjugates with gold-labelled reagents.Scanning Microscopy 1, 695?704.","journal-title":"Scanning Microscopy"},{"key":"CR26","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1177\/29.5.6166664","volume":"29","author":"J. Roth","year":"1981","unstructured":"Roth, J., Bendayan, M., Carlemalm, E., Villiger, W. &Garavito, M. (1981) Enhancement of structural preservation and immunocytochemical staining in low temperature embedded pancreastic tissue.J. Histochem. Cytochem. 29, 663?71.","journal-title":"J. Histochem. Cytochem."},{"key":"CR27","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1177\/26.3.632554","volume":"26","author":"J. Roth","year":"1978","unstructured":"Roth, J. &Binder, M. (1978) Colloidal gold, ferritin, and peroxidase as markers for electron microscopic double labelling lectin techniques.J. Histochem. Cytochem. 26, 163?9.","journal-title":"J. Histochem. Cytochem."},{"key":"CR28","doi-asserted-by":"crossref","first-page":"1189","DOI":"10.1083\/jcb.96.5.1189","volume":"96","author":"J. Roth","year":"1983","unstructured":"Roth, J., Brown, D. &Orci, L. (1983) Regional distribution ofN-acetyl-D-galactosamine residues in the glycocalyx of glomerular podocytes.J. Cell Biol. 96, 1189?96.","journal-title":"J. Cell Biol."},{"key":"CR29","doi-asserted-by":"crossref","first-page":"1167","DOI":"10.1177\/32.11.6208237","volume":"32","author":"J. Roth","year":"1984","unstructured":"Roth, J., Lucocq, J. M. &Charest, P. M. (1984) Light and electron microscopic demonstration of sialic acid residues with the lectin fromLimax flavus. A cytochemical affinity technique with the use of fetuin-gold complexes.J. Histochem. Cytochem. 32, 1167?76.","journal-title":"J. Histochem. Cytochem."},{"key":"CR30","first-page":"143","volume":"10","author":"J. Roth","year":"1975","unstructured":"Roth, J., Neupert, G. &Bolck, F. (1975) Concanavalin A receptors in the plasma membrane of rat liver cells: comparative electron microscopic studies on normal cells and on cellsin vivo transformed by diethylnitrosamine.Exp. Pathol. 10, 143?55.","journal-title":"Exp. Pathol."},{"key":"CR31","first-page":"449","volume":"39","author":"J. Roth","year":"1985","unstructured":"Roth, J. &Taatjes, D. J. (1985) Glycocalyx heterogeneity of rat kidney urinary tubule: demonstration with a lectin-gold technique specific for sialic acid.Eur. J. Cell Biol. 39, 449?57.","journal-title":"Eur. J. Cell Biol."},{"key":"CR32","doi-asserted-by":"crossref","first-page":"1969","DOI":"10.1073\/pnas.84.7.1969","volume":"84","author":"J. Roth","year":"1987","unstructured":"Roth, J., Taatjes, D. J., Bitter-Suermann, D. &Fine, J. (1987) Polysialic acid units are spatially and temporally expressed in developing postnatal rat kidney.Proc. Natl Acad. Sci. USA 84, 1969?73.","journal-title":"Proc. Natl Acad. Sci. USA"},{"key":"CR33","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1016\/0092-8674(85)90034-0","volume":"43","author":"J. Roth","year":"1985","unstructured":"Roth, J., Taatjes, D. J., Lucocq, J. M., Weinstejn, J. &Paulson, J. C. (1985) Demonstration of an extensivetrans-tubular network continuous with the Golgi apparatus stack that may function in glycosylation.Cell 43, 287?95.","journal-title":"Cell"},{"key":"CR34","doi-asserted-by":"crossref","first-page":"14307","DOI":"10.1016\/S0021-9258(18)67019-X","volume":"261","author":"J. Roth","year":"1986","unstructured":"Roth, J., Taatjes, D. J., Weinstein, J., Paulson, J. C., Grebnwell, P. &Watkins, W. M. (1986) Differential subcompartmentation of terminal glycosylation in the Golgi apparatus of intestinal absorptive and goblet cells.J Biol Chem. 261, 14307?12.","journal-title":"J Biol Chem."},{"key":"CR35","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1016\/S0065-2318(08)60109-2","volume":"40","author":"R. Schauer","year":"1982","unstructured":"Schauer, R. (1982) Chemistry, metabolism, and biological functions of sialic acids.Adv. Carbohyd. Chem. Biochem. 40, 131?234.","journal-title":"Adv. Carbohyd. Chem. Biochem."},{"key":"CR36","doi-asserted-by":"crossref","first-page":"1596","DOI":"10.1016\/S0021-9258(19)75677-4","volume":"262","author":"N. Shibuya","year":"1987","unstructured":"Shibuya, N., Goldstein, I. J., Broekaert, W. F., Nsimba-Lubaki, M., Peeters, B. &Peumans, W. J. (1987a) The elderberry (Sambucus nigra L.) bark lectin recognizes the Neu5Ac(?2,6)Gal\/GalNAc sequence.J. Biol. Chem. 262, 1596?1601.","journal-title":"J. Biol. Chem."},{"key":"CR37","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/0003-9861(87)90074-9","volume":"254","author":"N. Shibuya","year":"1987","unstructured":"Shibuya, N., Goldstein, I. J., Broekaert, W. F., Nsimba-Lubaki, M., Peeters, B. &Peumans, W. J. (1987b) Fractionation of sialylated oligosaccharides, glycopeptides, and glycoproteins on immobilized elderberry (Sambucus nigra L.) bark lectin.Arch. Biochem. Biophys. 254, 1?8.","journal-title":"Arch. Biochem. Biophys."},{"key":"CR38","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1083\/jcb.90.2.533","volume":"90","author":"J. Slot","year":"1981","unstructured":"Slot, J. &Geuze, H. J. (1981) Sizing of protein A-colloidal gold probes for immunoelectron microscopy.J. Cell Biol. 90, 533?6.","journal-title":"J. Cell Biol."},{"key":"CR39","first-page":"87","volume":"38","author":"J. W. Slot","year":"1985","unstructured":"Slot, J. W. &Geuze, H. J. (1985) A new method of preparing gold probes for multiple-labelling cytochemistry.Eur. J. Cell Biol. 38, 87?93.","journal-title":"Eur. J. Cell Biol."},{"key":"CR40","first-page":"860","volume":"27","author":"E. C. Stathis","year":"1958","unstructured":"Stathis, E. C. &Fabrikanos, A. (1958) Preparation of colloidal gold.Chem. Ind. 27, 860?1.","journal-title":"Chem. Ind."},{"key":"CR41","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1007\/BF01680634","volume":"19","author":"D. J. Taatjes","year":"1987","unstructured":"Taatjes, D. J., Schaub, U. &Koth, J. (1987a) Light microscopical detection of antigens and lectin binding sites with gold-labelling reagents on semi-thin Lowicryl K4M sections: usefulness of the photochemical silver reaction for signal amplification.Histochem. J. 19, 235?45.","journal-title":"Histochem. J."},{"key":"CR42","first-page":"151","volume":"45","author":"D. J. Taatjes","year":"1987","unstructured":"Taatjes, D. J., Chen, T.-H., Ackerstr\u00f6m, B., Bj\u00f6rck, L., Carlemalm, E. &Roth, J. (1987b) Streptococcal protein G-gold complex: comparison with staphylococcal protein A-gold complex for spot blotting and immunolabelling.Eur. J. Cell Biol. 45, 151?9.","journal-title":"Eur. J. Cell Biol."},{"key":"CR43","doi-asserted-by":"crossref","first-page":"6803","DOI":"10.1016\/S0021-9258(18)48316-0","volume":"262","author":"T. Tai","year":"1987","unstructured":"Tai, T., Sze, L., Kawashima, I., Saxton, R. E. &Irie, R. F. (1987) Monoclonal antibody detects monosialogangliosides having a sialic acid ?2,3-galactosyl residue.J. Biol. Chem. 262, 6803?7.","journal-title":"J. Biol. Chem."},{"key":"CR44","doi-asserted-by":"crossref","first-page":"4350","DOI":"10.1073\/pnas.76.9.4350","volume":"76","author":"H. Towbin","year":"1979","unstructured":"Towbin, H., Staehelin, T. &Gordon, J. (1979) Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications.Proc. Natl Acad. Sci. USA 76, 4350?4.","journal-title":"Proc. Natl Acad. Sci. USA"},{"key":"CR45","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1007\/BF01002773","volume":"11","author":"K. Yamada","year":"1979","unstructured":"Yamada, K. &Shimizu, S. (1979) The use of peroxidaselabelledLimulus polyphemus agglutinin for the histochemistry of sialic acid-containing glycoproteins in light microscopy.Histochem. J. 11, 457?71.","journal-title":"Histochem. J."}],"container-title":["The Histochemical Journal"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF01002646.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/BF01002646\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF01002646","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,7,4]],"date-time":"2021-07-04T03:36:44Z","timestamp":1625369804000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/BF01002646"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1988,9]]},"references-count":45,"journal-issue":{"issue":"9","published-print":{"date-parts":[[1988,9]]}},"alternative-id":["BF01002646"],"URL":"https:\/\/doi.org\/10.1007\/bf01002646","relation":{},"ISSN":["0018-2214","1573-6865"],"issn-type":[{"value":"0018-2214","type":"print"},{"value":"1573-6865","type":"electronic"}],"subject":[],"published":{"date-parts":[[1988,9]]}}}